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The map label for this gene is uxaA [H]

Identifier: 159041705

GI number: 159041705

Start: 1196809

End: 1197984

Strand: Reverse

Name: uxaA [H]

Synonym: Cmaq_1140

Alternate gene names: 159041705

Gene position: 1197984-1196809 (Counterclockwise)

Preceding gene: 159041706

Following gene: 159041704

Centisome position: 57.66

GC content: 46.43

Gene sequence:

>1176_bases
GTGAGTGATGTGGCTGGCAAATACCCAACCATTAAGGCGTACATTAGGCCTGATGGAAGCGTAGGGGTAAGGAACCACGT
AGCCATAATACCCATTGATGACTTATCAAACACAGCCGCCTTAGGTGTGGCTAAGTTAATTAGGGGTACTGTGGCTATAC
CGCACCCATACGGTAGATTACAGTTCGGTAGGGACTTGAATCTACTATTCCATGTATTATCCGGCACTGGGGCTAATCCC
AATGTATACGGCGCCATAGTTATTGGTATTGAGGATAATTGGGCTAATAAGGTTGCTGATGTGATAGCTAAGACGGGTAA
GCCGGTTTACGTATTCAGTATTGAGGGTAATGGTGATTTAAAAACCATTGAGGCAGCGGCTAGGAAGGCTAAGGAGCTTG
TTCAGGATGCTGGTGAGCAGCAGAGAACTGAGGTTGATTTAACAGGCATAGTGTTCAGTATAAAGTGCGGTGAATCAGAC
ACCACATCAGGCTTAGCATCAAACCCAGCATTAGGGCATACTGTGGATAAGTTGGTGGATTTAGGGAATACGGTAATGTT
TGGTGAAACCTCAGAGCTAACGGGGGCTGAGGATATTGTAGCCAGTCGCATAAAGGATCCTGAGTTAAGGAGTAAATTCA
TGAGGATTTACAACGAGTACGTTGAGGTAATTGAAAGGGAAGGCGTTGACCTACTTGGTTCACAGCCAACTGAAGGCAAT
ATTAAAGGCGGTTTATCAACAATAGAGGAGAAGGCACTAGGCAACATTCAGAAATTAGGCACTAGGCCAATTACGTGTGT
TGCCGATTACCTGGACCCAGTACCAAGGAACGGGGGCTTATGCTTCGTTAACACTTCATCAGCAGCCGCGGAGGCTGTGA
CGTTATTCGCCGCTAAGGGCTCTGTGCTTCACTTCTTCACCACAGGTCAAGGTAACGTGGTGGGTCATCCAATAATACCT
GTTATCAAGATTTCAGCCAACCCAAAGACCGTTAAGGCAATGGGTGAGCACATTGACGTTGATGTATCAGACCTACTGGA
GCTTAAGGTTAGCCTACAGGAGGCTGGGGATAGGATCTTCAACTACGCGTTAAGGGTAATGAATGGTAGATTAACCGCAG
CTGAGGCGCTTCAGCATGATGAATTCTCACCCATTAAACTATACGTGAGTGCGTGA

Upstream 100 bases:

>100_bases
ATGGTAGGGTAATTGGGGTTGCTGTGAAGGATATTAAGGCTGGGGAACATGTTCATACACATAATCTAAAATCATTAAGG
TGGGGTAACTTAAGTAAAAG

Downstream 100 bases:

>100_bases
GTAATAATGCCTAAGTTAAACACCATTAAGTTAATACCAGTCTCAATACCGTACATTGATGATCCACCCACAGTATTTCA
GGAGGCTTGGGGTCGTCAAC

Product: D-galactarate dehydratase/Altronate hydrolase domain-containing protein

Products: NA

Alternate protein names: Altronic acid hydratase [H]

Number of amino acids: Translated: 391; Mature: 390

Protein sequence:

>391_residues
MSDVAGKYPTIKAYIRPDGSVGVRNHVAIIPIDDLSNTAALGVAKLIRGTVAIPHPYGRLQFGRDLNLLFHVLSGTGANP
NVYGAIVIGIEDNWANKVADVIAKTGKPVYVFSIEGNGDLKTIEAAARKAKELVQDAGEQQRTEVDLTGIVFSIKCGESD
TTSGLASNPALGHTVDKLVDLGNTVMFGETSELTGAEDIVASRIKDPELRSKFMRIYNEYVEVIEREGVDLLGSQPTEGN
IKGGLSTIEEKALGNIQKLGTRPITCVADYLDPVPRNGGLCFVNTSSAAAEAVTLFAAKGSVLHFFTTGQGNVVGHPIIP
VIKISANPKTVKAMGEHIDVDVSDLLELKVSLQEAGDRIFNYALRVMNGRLTAAEALQHDEFSPIKLYVSA

Sequences:

>Translated_391_residues
MSDVAGKYPTIKAYIRPDGSVGVRNHVAIIPIDDLSNTAALGVAKLIRGTVAIPHPYGRLQFGRDLNLLFHVLSGTGANP
NVYGAIVIGIEDNWANKVADVIAKTGKPVYVFSIEGNGDLKTIEAAARKAKELVQDAGEQQRTEVDLTGIVFSIKCGESD
TTSGLASNPALGHTVDKLVDLGNTVMFGETSELTGAEDIVASRIKDPELRSKFMRIYNEYVEVIEREGVDLLGSQPTEGN
IKGGLSTIEEKALGNIQKLGTRPITCVADYLDPVPRNGGLCFVNTSSAAAEAVTLFAAKGSVLHFFTTGQGNVVGHPIIP
VIKISANPKTVKAMGEHIDVDVSDLLELKVSLQEAGDRIFNYALRVMNGRLTAAEALQHDEFSPIKLYVSA
>Mature_390_residues
SDVAGKYPTIKAYIRPDGSVGVRNHVAIIPIDDLSNTAALGVAKLIRGTVAIPHPYGRLQFGRDLNLLFHVLSGTGANPN
VYGAIVIGIEDNWANKVADVIAKTGKPVYVFSIEGNGDLKTIEAAARKAKELVQDAGEQQRTEVDLTGIVFSIKCGESDT
TSGLASNPALGHTVDKLVDLGNTVMFGETSELTGAEDIVASRIKDPELRSKFMRIYNEYVEVIEREGVDLLGSQPTEGNI
KGGLSTIEEKALGNIQKLGTRPITCVADYLDPVPRNGGLCFVNTSSAAAEAVTLFAAKGSVLHFFTTGQGNVVGHPIIPV
IKISANPKTVKAMGEHIDVDVSDLLELKVSLQEAGDRIFNYALRVMNGRLTAAEALQHDEFSPIKLYVSA

Specific function: Hexuronate conversion to KDG. [C]

COG id: COG2721

COG function: function code G; Altronate dehydratase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the uxaA family [H]

Homologues:

Organism=Escherichia coli, GI1789475, Length=399, Percent_Identity=26.5664160401003, Blast_Score=120, Evalue=2e-28,
Organism=Escherichia coli, GI1789516, Length=392, Percent_Identity=26.530612244898, Blast_Score=114, Evalue=7e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007392
- InterPro:   IPR013974 [H]

Pfam domain/function: PF04295 GD_AH_C; PF08666 SAF [H]

EC number: =4.2.1.7 [H]

Molecular weight: Translated: 41752; Mature: 41621

Theoretical pI: Translated: 5.45; Mature: 5.45

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDVAGKYPTIKAYIRPDGSVGVRNHVAIIPIDDLSNTAALGVAKLIRGTVAIPHPYGRL
CCCCCCCCCEEEEEECCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHCCEECCCCCCCC
QFGRDLNLLFHVLSGTGANPNVYGAIVIGIEDNWANKVADVIAKTGKPVYVFSIEGNGDL
CCCCCHHHHHHHHHCCCCCCCEEEEEEEEECCCHHHHHHHHHHHCCCEEEEEEEECCCCH
KTIEAAARKAKELVQDAGEQQRTEVDLTGIVFSIKCGESDTTSGLASNPALGHTVDKLVD
HHHHHHHHHHHHHHHHCCHHHHCEEEEEEEEEEEEECCCCCCCCCCCCCCCCHHHHHHHH
LGNTVMFGETSELTGAEDIVASRIKDPELRSKFMRIYNEYVEVIEREGVDLLGSQPTEGN
CCCEEEECCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
IKGGLSTIEEKALGNIQKLGTRPITCVADYLDPVPRNGGLCFVNTSSAAAEAVTLFAAKG
CCCCHHHHHHHHHCCHHHHCCCCHHHHHHHHCCCCCCCCEEEEECCCHHHHEEEEEEECC
SVLHFFTTGQGNVVGHPIIPVIKISANPKTVKAMGEHIDVDVSDLLELKVSLQEAGDRIF
CEEEEEECCCCCEECCCCEEEEEECCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHH
NYALRVMNGRLTAAEALQHDEFSPIKLYVSA
HHHHHHHCCCCHHHHHHCCCCCCCEEEEEEC
>Mature Secondary Structure 
SDVAGKYPTIKAYIRPDGSVGVRNHVAIIPIDDLSNTAALGVAKLIRGTVAIPHPYGRL
CCCCCCCCEEEEEECCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHCCEECCCCCCCC
QFGRDLNLLFHVLSGTGANPNVYGAIVIGIEDNWANKVADVIAKTGKPVYVFSIEGNGDL
CCCCCHHHHHHHHHCCCCCCCEEEEEEEEECCCHHHHHHHHHHHCCCEEEEEEEECCCCH
KTIEAAARKAKELVQDAGEQQRTEVDLTGIVFSIKCGESDTTSGLASNPALGHTVDKLVD
HHHHHHHHHHHHHHHHCCHHHHCEEEEEEEEEEEEECCCCCCCCCCCCCCCCHHHHHHHH
LGNTVMFGETSELTGAEDIVASRIKDPELRSKFMRIYNEYVEVIEREGVDLLGSQPTEGN
CCCEEEECCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
IKGGLSTIEEKALGNIQKLGTRPITCVADYLDPVPRNGGLCFVNTSSAAAEAVTLFAAKG
CCCCHHHHHHHHHCCHHHHCCCCHHHHHHHHCCCCCCCCEEEEECCCHHHHEEEEEEECC
SVLHFFTTGQGNVVGHPIIPVIKISANPKTVKAMGEHIDVDVSDLLELKVSLQEAGDRIF
CEEEEEECCCCCEECCCCEEEEEECCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHH
NYALRVMNGRLTAAEALQHDEFSPIKLYVSA
HHHHHHHCCCCHHHHHHCCCCCCCEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9579062; 9384377 [H]