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The map label for this gene is thrC [H]

Identifier: 159041641

GI number: 159041641

Start: 1125054

End: 1126127

Strand: Reverse

Name: thrC [H]

Synonym: Cmaq_1074

Alternate gene names: 159041641

Gene position: 1126127-1125054 (Counterclockwise)

Preceding gene: 159041642

Following gene: 159041640

Centisome position: 54.2

GC content: 46.55

Gene sequence:

>1074_bases
ATGGTGCTTAACTTAACTAACATGAGCGGGGAGGTAACGTACAAGTGCCCTAAATGCGGCTTCACAACCGAGGCTAATAC
CTGGCTTATCAAGTGCCCTAGATGCGGGTCACCGTTGAATGTGAATTATGATTTAAGGAGACCTAGGGAGCTTAGTAGAA
GTGAATTAACGAGGATTCTACCTGTTAAGGAGCCGTTAAGCCTTGGTGAAGGTTTAACCCCACTGGTTAGGAGGGGTGAT
TACTACTTTAAGCTTGAGTACCTTAACCCCACTGGTTCATTTAAGGATAGGGGGTGGAGTCTTGCCCTATCAGTACTACG
TAATGACGTCACTGTGGTTGAGGATTCAAGCGGTAATGCTGGACTATCCCTAGCAGCATACTCCGCGGTTAAGGGGGTTA
GGGCTAGGATTTACGTCCCTAAGACGGCCCCTGAGGCTAAGAAGAGACTTATGAGGCTCCTAGGCGCTAATGTGGTTGAG
GCTGCAACTAGGGCTGATGCATCATCACTTGCCATGAGCTTCACAGAGGGGGTTTACGTTGGTCATTCATGGAACCCCTT
CTTCATACATGGCGTTAAGTTAATAGCTTATGAACTAGCATTAGAATTAGGGAACATTGATAATGTTGTTGCACCCCTAG
GTAACGGTACCTTAACCCTAGGCCTATACTTAGGTTTCAAGGAGGCTGAGGAATTGAAGCTTATTAAAGACACACCTAGG
ATAATAGCCGTTGAGGCATCAGGCTACGAGTGGGCTTACAGTATGCTTCACAACACACCCATGGGTGTTAAGGCAACCTT
ACCCGACGGCATAATAGTGCCCCAGCCACCTAGGTTAACTCAGATAATTGACGCGATACGGGACACTGGAGGTGACGTGG
TGGTTGTTAATGATCAGGGGGTTATTGAGGGGTTAAGGGAGGGTATTAGGTTAGGGTTCATAATTGAGCCAACAAGCGCA
GTTGTCTTTAAGGCCCTTAAGGAAGTGAACCTAAGTGGCACAACTGTAGTTATTTTAACGGGTTCAGGCTTAAAGCTGAG
TAATGAACTGTATCGGTTAATATACGGTGAATGA

Upstream 100 bases:

>100_bases
ACGGCTTAATTTAAAAAAGGCCCTAAGCAAGTATTTCAATAATACCTAGAAGTATTCCTAACCGTGAATTAGTTTTAAAG
CTGAGCACAGTTCCTTATTC

Downstream 100 bases:

>100_bases
TCTAAGACCCATGATTCACCTTAAATATCGTACTCATCCTCACTAGACTTAGTAAACCCTCGAGGACTAATTTATGTAAG
ATGCGTTAAGTTGAGTTAAT

Product: pyridoxal-5'-phosphate-dependent protein subunit beta

Products: NA

Alternate protein names: TS [H]

Number of amino acids: Translated: 357; Mature: 357

Protein sequence:

>357_residues
MVLNLTNMSGEVTYKCPKCGFTTEANTWLIKCPRCGSPLNVNYDLRRPRELSRSELTRILPVKEPLSLGEGLTPLVRRGD
YYFKLEYLNPTGSFKDRGWSLALSVLRNDVTVVEDSSGNAGLSLAAYSAVKGVRARIYVPKTAPEAKKRLMRLLGANVVE
AATRADASSLAMSFTEGVYVGHSWNPFFIHGVKLIAYELALELGNIDNVVAPLGNGTLTLGLYLGFKEAEELKLIKDTPR
IIAVEASGYEWAYSMLHNTPMGVKATLPDGIIVPQPPRLTQIIDAIRDTGGDVVVVNDQGVIEGLREGIRLGFIIEPTSA
VVFKALKEVNLSGTTVVILTGSGLKLSNELYRLIYGE

Sequences:

>Translated_357_residues
MVLNLTNMSGEVTYKCPKCGFTTEANTWLIKCPRCGSPLNVNYDLRRPRELSRSELTRILPVKEPLSLGEGLTPLVRRGD
YYFKLEYLNPTGSFKDRGWSLALSVLRNDVTVVEDSSGNAGLSLAAYSAVKGVRARIYVPKTAPEAKKRLMRLLGANVVE
AATRADASSLAMSFTEGVYVGHSWNPFFIHGVKLIAYELALELGNIDNVVAPLGNGTLTLGLYLGFKEAEELKLIKDTPR
IIAVEASGYEWAYSMLHNTPMGVKATLPDGIIVPQPPRLTQIIDAIRDTGGDVVVVNDQGVIEGLREGIRLGFIIEPTSA
VVFKALKEVNLSGTTVVILTGSGLKLSNELYRLIYGE
>Mature_357_residues
MVLNLTNMSGEVTYKCPKCGFTTEANTWLIKCPRCGSPLNVNYDLRRPRELSRSELTRILPVKEPLSLGEGLTPLVRRGD
YYFKLEYLNPTGSFKDRGWSLALSVLRNDVTVVEDSSGNAGLSLAAYSAVKGVRARIYVPKTAPEAKKRLMRLLGANVVE
AATRADASSLAMSFTEGVYVGHSWNPFFIHGVKLIAYELALELGNIDNVVAPLGNGTLTLGLYLGFKEAEELKLIKDTPR
IIAVEASGYEWAYSMLHNTPMGVKATLPDGIIVPQPPRLTQIIDAIRDTGGDVVVVNDQGVIEGLREGIRLGFIIEPTSA
VVFKALKEVNLSGTTVVILTGSGLKLSNELYRLIYGE

Specific function: Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine [H]

COG id: COG0498

COG function: function code E; Threonine synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the threonine synthase family [H]

Homologues:

Organism=Homo sapiens, GI11345492, Length=295, Percent_Identity=26.4406779661017, Blast_Score=82, Evalue=9e-16,
Organism=Escherichia coli, GI1789505, Length=234, Percent_Identity=28.2051282051282, Blast_Score=61, Evalue=1e-10,
Organism=Caenorhabditis elegans, GI17508781, Length=255, Percent_Identity=29.4117647058824, Blast_Score=68, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI71991565, Length=205, Percent_Identity=28.780487804878, Blast_Score=64, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001926
- InterPro:   IPR000634
- InterPro:   IPR004450 [H]

Pfam domain/function: PF00291 PALP [H]

EC number: =4.2.3.1 [H]

Molecular weight: Translated: 38948; Mature: 38948

Theoretical pI: Translated: 8.27; Mature: 8.27

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVLNLTNMSGEVTYKCPKCGFTTEANTWLIKCPRCGSPLNVNYDLRRPRELSRSELTRIL
CEEEEECCCCEEEEECCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCHHCCHHHHHHHC
PVKEPLSLGEGLTPLVRRGDYYFKLEYLNPTGSFKDRGWSLALSVLRNDVTVVEDSSGNA
CCCCCHHCCCCCCHHHHCCCEEEEEEEECCCCCCCCCCHHHHHHHHHCCEEEEECCCCCC
GLSLAAYSAVKGVRARIYVPKTAPEAKKRLMRLLGANVVEAATRADASSLAMSFTEGVYV
CEEHHHHHHHCCCEEEEEECCCCHHHHHHHHHHHCCHHHHHHHHCCHHHHHHHHHCCEEE
GHSWNPFFIHGVKLIAYELALELGNIDNVVAPLGNGTLTLGLYLGFKEAEELKLIKDTPR
CCCCCCEEEHHHHHHHHHHHHHHCCCCCEEEECCCCEEEEEEEECCCCCCCEEEEECCCC
IIAVEASGYEWAYSMLHNTPMGVKATLPDGIIVPQPPRLTQIIDAIRDTGGDVVVVNDQG
EEEEECCCCHHHHHHHHCCCCCEEEECCCCEECCCCCHHHHHHHHHHCCCCCEEEECCCH
VIEGLREGIRLGFIIEPTSAVVFKALKEVNLSGTTVVILTGSGLKLSNELYRLIYGE
HHHHHHCCCEEEEEECCHHHHHHHHHHHCCCCCCEEEEEECCCCEECCHHHEEECCC
>Mature Secondary Structure
MVLNLTNMSGEVTYKCPKCGFTTEANTWLIKCPRCGSPLNVNYDLRRPRELSRSELTRIL
CEEEEECCCCEEEEECCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCHHCCHHHHHHHC
PVKEPLSLGEGLTPLVRRGDYYFKLEYLNPTGSFKDRGWSLALSVLRNDVTVVEDSSGNA
CCCCCHHCCCCCCHHHHCCCEEEEEEEECCCCCCCCCCHHHHHHHHHCCEEEEECCCCCC
GLSLAAYSAVKGVRARIYVPKTAPEAKKRLMRLLGANVVEAATRADASSLAMSFTEGVYV
CEEHHHHHHHCCCEEEEEECCCCHHHHHHHHHHHCCHHHHHHHHCCHHHHHHHHHCCEEE
GHSWNPFFIHGVKLIAYELALELGNIDNVVAPLGNGTLTLGLYLGFKEAEELKLIKDTPR
CCCCCCEEEHHHHHHHHHHHHHHCCCCCEEEECCCCEEEEEEEECCCCCCCEEEEECCCC
IIAVEASGYEWAYSMLHNTPMGVKATLPDGIIVPQPPRLTQIIDAIRDTGGDVVVVNDQG
EEEEECCCCHHHHHHHHCCCCCEEEECCCCEECCCCCHHHHHHHHHHCCCCCEEEECCCH
VIEGLREGIRLGFIIEPTSAVVFKALKEVNLSGTTVVILTGSGLKLSNELYRLIYGE
HHHHHHCCCEEEEEECCHHHHHHHHHHHCCCCCCEEEEEECCCCEECCHHHEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]