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The map label for this gene is yleA [C]

Identifier: 159041572

GI number: 159041572

Start: 1056091

End: 1057359

Strand: Reverse

Name: yleA [C]

Synonym: Cmaq_1003

Alternate gene names: 159041572

Gene position: 1057359-1056091 (Counterclockwise)

Preceding gene: 159041573

Following gene: 159041571

Centisome position: 50.89

GC content: 43.58

Gene sequence:

>1269_bases
GTGCCCACGTACTACATTGAGACTTATGGTTGCTGGCTGAATAAGGCTGATTCAGCATTAATGGAGGAGGATTTAAGGAG
AATGGGTTACGTTAAGGTTAATGATCCTGCTCAAGCAGACTTAATACTAGTTAATACATGTGCTGTTAGGGAGGATTCAG
AGATTAGGGAACTTAAGGCTATTGAGAAGTACTCTAGGTTAGGTAAGAAGCTAATAGTGGCCGGGTGCTTAACTAAGGCA
AGGCCCAGTGAAATAATGAGACTAGCCCCTGACGCATTAATAGTGAATCCAAGTTCCGTTGAAAATTTGGCCGAGTTGTT
AAAGGGTGGTGTTAATTTAACTGAGAGGTTAATGGTTAGGATTCCTAAGTACTATGAATCAAGCCACGTTTACGTTGTGC
CTATTCAAGTTGGTTGCCTTGGTAACTGCTCATACTGCGTTATCAAATACACTAGGGGTGGTATGGGTTGGGTTAAGAGC
GCTGATTTAAGCGTGGTTAAGGAATCCATAGCCAAGGCAGTGGCAAGGGGTGCTAGGGAGATTTACTTAACTGGACAGGA
GATTTCAGCGTACGGTAAGGATAAGGGTTATGACTTAGTTGACTTACTTGAGGCAGTATTGAGGGATGTTGAGGGAAGGT
ACTTGATTAGGTTAGGTATGCTTGAGCCACTGGAGCTTGAGGGGATGATACATAGGTTAATTGATGTAATTAAGAATGAC
TGGAGAATCTACAGGTTCTTCCACATACCTGTGCAAAGCGGTAGTGATAAGGTGCTTAGATTAATGAAGCGTAAGTACAC
TGTGGATTTGTTTAAACGGGAAGTGGAGTTAATTAGGAGGAGCTTCCGTAACTCATTCATAGCCACAGACATCATAGTTG
GCCACCCTGGGGAGGATGATTCTGATTTCCAGGAGAGCGTTAGGTTGATTAGGGAACTAGGTATTGATAAGGTTCATGTC
GCCAGATATAGCCCAAGACCATTCACTGAGGCTGCTTACATGCGTCAAGTACCTGATCAGGTTAAGAAGCAGAGGAGCAG
CATGTTAAGTAAGGTGGCCCTTGAGGTGGCGTATTCCAGGAACCTTGAGTACGTTGGCGGCACCTACGAGGGGTTAATTA
GCTCAATTGGGTTTAAGGGTAGGGGACTTATGGCTAGGTTAATGGACTATAGGCCAGTTATCATTAATGAGGGTGACTTA
GGCTCATTCGTGAAAATTAAGGTAACTGGGGCCTCATCAATAAACTTAATCGGCAAAATAATTGAATGA

Upstream 100 bases:

>100_bases
CAGTAGTAAGAGAAGCATACGAAGTAAAGGTTACAGAGAGACACTAGGTGATTTTTAATACGTGTTTAAAGGTTTTTAAA
TAAAGCATGAATAGGGGATT

Downstream 100 bases:

>100_bases
AACCAATACCGGTTTCTTAACTAATCCATCACATTAATTAACCCTTAATGAGAAGCATGATTTCTTACTAGTAAAACTTA
ATAAGTATACTTAATGATAA

Product: RNA modification protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 422; Mature: 421

Protein sequence:

>422_residues
MPTYYIETYGCWLNKADSALMEEDLRRMGYVKVNDPAQADLILVNTCAVREDSEIRELKAIEKYSRLGKKLIVAGCLTKA
RPSEIMRLAPDALIVNPSSVENLAELLKGGVNLTERLMVRIPKYYESSHVYVVPIQVGCLGNCSYCVIKYTRGGMGWVKS
ADLSVVKESIAKAVARGAREIYLTGQEISAYGKDKGYDLVDLLEAVLRDVEGRYLIRLGMLEPLELEGMIHRLIDVIKND
WRIYRFFHIPVQSGSDKVLRLMKRKYTVDLFKREVELIRRSFRNSFIATDIIVGHPGEDDSDFQESVRLIRELGIDKVHV
ARYSPRPFTEAAYMRQVPDQVKKQRSSMLSKVALEVAYSRNLEYVGGTYEGLISSIGFKGRGLMARLMDYRPVIINEGDL
GSFVKIKVTGASSINLIGKIIE

Sequences:

>Translated_422_residues
MPTYYIETYGCWLNKADSALMEEDLRRMGYVKVNDPAQADLILVNTCAVREDSEIRELKAIEKYSRLGKKLIVAGCLTKA
RPSEIMRLAPDALIVNPSSVENLAELLKGGVNLTERLMVRIPKYYESSHVYVVPIQVGCLGNCSYCVIKYTRGGMGWVKS
ADLSVVKESIAKAVARGAREIYLTGQEISAYGKDKGYDLVDLLEAVLRDVEGRYLIRLGMLEPLELEGMIHRLIDVIKND
WRIYRFFHIPVQSGSDKVLRLMKRKYTVDLFKREVELIRRSFRNSFIATDIIVGHPGEDDSDFQESVRLIRELGIDKVHV
ARYSPRPFTEAAYMRQVPDQVKKQRSSMLSKVALEVAYSRNLEYVGGTYEGLISSIGFKGRGLMARLMDYRPVIINEGDL
GSFVKIKVTGASSINLIGKIIE
>Mature_421_residues
PTYYIETYGCWLNKADSALMEEDLRRMGYVKVNDPAQADLILVNTCAVREDSEIRELKAIEKYSRLGKKLIVAGCLTKAR
PSEIMRLAPDALIVNPSSVENLAELLKGGVNLTERLMVRIPKYYESSHVYVVPIQVGCLGNCSYCVIKYTRGGMGWVKSA
DLSVVKESIAKAVARGAREIYLTGQEISAYGKDKGYDLVDLLEAVLRDVEGRYLIRLGMLEPLELEGMIHRLIDVIKNDW
RIYRFFHIPVQSGSDKVLRLMKRKYTVDLFKREVELIRRSFRNSFIATDIIVGHPGEDDSDFQESVRLIRELGIDKVHVA
RYSPRPFTEAAYMRQVPDQVKKQRSSMLSKVALEVAYSRNLEYVGGTYEGLISSIGFKGRGLMARLMDYRPVIINEGDLG
SFVKIKVTGASSINLIGKIIE

Specific function: Unknown

COG id: COG0621

COG function: function code J; 2-methylthioadenine synthetase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 TRAM domain [H]

Homologues:

Organism=Homo sapiens, GI93277076, Length=422, Percent_Identity=32.4644549763033, Blast_Score=216, Evalue=4e-56,
Organism=Homo sapiens, GI28872784, Length=483, Percent_Identity=27.3291925465839, Blast_Score=138, Evalue=9e-33,
Organism=Homo sapiens, GI28872782, Length=483, Percent_Identity=27.3291925465839, Blast_Score=138, Evalue=1e-32,
Organism=Escherichia coli, GI1786882, Length=443, Percent_Identity=29.1196388261851, Blast_Score=165, Evalue=6e-42,
Organism=Escherichia coli, GI1787057, Length=430, Percent_Identity=27.4418604651163, Blast_Score=121, Evalue=1e-28,
Organism=Caenorhabditis elegans, GI71996771, Length=359, Percent_Identity=29.5264623955432, Blast_Score=157, Evalue=1e-38,
Organism=Caenorhabditis elegans, GI17553146, Length=465, Percent_Identity=25.1612903225806, Blast_Score=118, Evalue=5e-27,
Organism=Drosophila melanogaster, GI19922432, Length=434, Percent_Identity=30.6451612903226, Blast_Score=201, Evalue=6e-52,
Organism=Drosophila melanogaster, GI21356207, Length=402, Percent_Identity=25.6218905472637, Blast_Score=125, Evalue=4e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006638
- InterPro:   IPR005839
- InterPro:   IPR020612
- InterPro:   IPR013848
- InterPro:   IPR006466
- InterPro:   IPR007197
- InterPro:   IPR002792 [H]

Pfam domain/function: PF04055 Radical_SAM; PF01938 TRAM; PF00919 UPF0004 [H]

EC number: NA

Molecular weight: Translated: 47697; Mature: 47566

Theoretical pI: Translated: 9.09; Mature: 9.09

Prosite motif: PS50926 TRAM ; PS01278 UPF0004

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPTYYIETYGCWLNKADSALMEEDLRRMGYVKVNDPAQADLILVNTCAVREDSEIRELKA
CCCEEEEEECCHHCCHHHHHHHHHHHHCCCEEECCCCCCCEEEEEEECCCCCHHHHHHHH
IEKYSRLGKKLIVAGCLTKARPSEIMRLAPDALIVNPSSVENLAELLKGGVNLTERLMVR
HHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCEEEECCHHHHHHHHHHHCCCCHHHHHHHH
IPKYYESSHVYVVPIQVGCLGNCSYCVIKYTRGGMGWVKSADLSVVKESIAKAVARGARE
HHHHHCCCCEEEEEEEEEECCCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHCCCEE
IYLTGQEISAYGKDKGYDLVDLLEAVLRDVEGRYLIRLGMLEPLELEGMIHRLIDVIKND
EEEECHHHHCCCCCCCCCHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHHHHCC
WRIYRFFHIPVQSGSDKVLRLMKRKYTVDLFKREVELIRRSFRNSFIATDIIVGHPGEDD
CEEEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEECCCCCC
SDFQESVRLIRELGIDKVHVARYSPRPFTEAAYMRQVPDQVKKQRSSMLSKVALEVAYSR
HHHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
NLEYVGGTYEGLISSIGFKGRGLMARLMDYRPVIINEGDLGSFVKIKVTGASSINLIGKI
CCCCCCCCHHHHHHHCCCCCCHHHHHHHCCCCEEEECCCCCCEEEEEEECCCCHHHHHHH
IE
CC
>Mature Secondary Structure 
PTYYIETYGCWLNKADSALMEEDLRRMGYVKVNDPAQADLILVNTCAVREDSEIRELKA
CCEEEEEECCHHCCHHHHHHHHHHHHCCCEEECCCCCCCEEEEEEECCCCCHHHHHHHH
IEKYSRLGKKLIVAGCLTKARPSEIMRLAPDALIVNPSSVENLAELLKGGVNLTERLMVR
HHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCEEEECCHHHHHHHHHHHCCCCHHHHHHHH
IPKYYESSHVYVVPIQVGCLGNCSYCVIKYTRGGMGWVKSADLSVVKESIAKAVARGARE
HHHHHCCCCEEEEEEEEEECCCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHCCCEE
IYLTGQEISAYGKDKGYDLVDLLEAVLRDVEGRYLIRLGMLEPLELEGMIHRLIDVIKND
EEEECHHHHCCCCCCCCCHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHHHHCC
WRIYRFFHIPVQSGSDKVLRLMKRKYTVDLFKREVELIRRSFRNSFIATDIIVGHPGEDD
CEEEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEECCCCCC
SDFQESVRLIRELGIDKVHVARYSPRPFTEAAYMRQVPDQVKKQRSSMLSKVALEVAYSR
HHHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
NLEYVGGTYEGLISSIGFKGRGLMARLMDYRPVIINEGDLGSFVKIKVTGASSINLIGKI
CCCCCCCCHHHHHHHCCCCCCHHHHHHHCCCCEEEECCCCCCEEEEEEECCCCHHHHHHH
IE
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]