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The map label for this gene is dxs [C]

Identifier: 159041382

GI number: 159041382

Start: 844450

End: 846228

Strand: Reverse

Name: dxs [C]

Synonym: Cmaq_0809

Alternate gene names: 159041382

Gene position: 846228-844450 (Counterclockwise)

Preceding gene: 159041387

Following gene: 159041381

Centisome position: 40.73

GC content: 45.36

Gene sequence:

>1779_bases
ATGCTTAAAAATATAGATTGTATAGGCTGTTTAGATTGGTATGGAATTCGGGACCCACGTGGAATACCTGGAATGGTAAA
AGAGGCTAAGGTGAACCTGGTTAATAGGGTTAAGGAGATAAGTAATAAGGCCCGTTCAATATTGGTTGGGTTAAGCCTAA
TAGATCCACATATTCACTTGGGCTCATCCCTATCAAGCATAGATATTATAGCTACACTATACTTAATGACTAATGTACGT
GATAATGATCCATTAAGGAGGGATTACGTAATATTATCAAAGGGTCACGCAGCCCCAGCATTATACGTGGTGTTATCGGA
ATTAGGCCTAGTTAATAGGGAGGAGTTAATGATGATTAATGAACCCTGGAGCCCACTGCAGGGTCACCCTGAGGTTAAGT
TACCAACAGTACCAGTATCCACAGGTAGTCTAGCGCAGGGGTTAAGTACAGCCGTGGGTATTGCAAGGGGGTTAATGGCT
AGGGAGGCCTCAGGTAAGGTTTTCGTAATAGTGGGTGATGGTGAATTAGATGAGGGGCAGGCCTGGGAGGCGTTAATGGA
TATTGCTGAATCTAAGTTAAGCAACTTATTCATAATAATTGACTACAATGGTGTTCAATTAGATGGACCAGTGAGGGGTA
TTAAATCAACGTTAACTGAGGCACTTAAGTCACTGGGATTCACCGTACTGGAGTGTGATGGACATGACCCAGAGGCCTTG
ATTGATACTCTGATTCAAGCACATAAGGTAAATGGACCCAAGGTTATAGTAGCCAGAACCATTAGGGGGAAGGGGGTTTC
CGACATTGAGGGAACCAGTAAACAGAGGATACTGGATGATGGTGGGGAACCTGGCTTCGGATCAATGAGGGATGCTGTCG
GCAGGGCTCTCCTTGAGGCGGGTGAAAGGTACAATGACTTATACGTGGTTACAGCTGATGTAGGTGGGTCAACAAGGGCT
ATTTGGTTTAAGGAGAAGTTCCCCAACAGGTACATTGACGTTGGTATAGCTGAACAACACATGATTGGTGTAGCCAGTGG
ATTAGCCTTAACAGGCCTTAGACCTGTGGCCATTGGGTTCGCAATGTTCATAATGAGGGCTTGGGAACAGGTTAGGAATA
CGGTATCTAGGATGAATCTTAACGTTAAGATTATTGGAACCCACTCCGGCTTAAGCGATTACGCTGATGGGGCTTCCCAC
CAAACCTTCGAGGACATATCACTAATGAGGACTCTACCAAACATGACCATTGTAGTACCCGCCGACCCCAATGAGGCTGG
TAAAGCTGTGTTAGCGTTAATGGAGCATCAGGGACCAGCCTACGTCAGGATTGGTAGGGATTACGGACCCAGGGTAACTA
ATGGTGATGAATTCAAGCTAGGTAAGGCCTCAGTGCTTAGGGATGGGGATGATTTAGCAATTATTGGTGCTGGACCAGTC
CTATGGGATGCTTTAATGGCTGCTGAGGAATTAGGTAAAATGGGGGTATCGGTAATGGTCATTAACCTAAGCACGATTAA
ACCCATTGACGTTGACACTGTGGTTAAGGCAGCTAAGAGAACTGGGGCGGTATTGACTATTGAGGAGCATTCAACACATG
GTGGGGTTGGTTCAGCGGTAGCTGAGGTGCTTTCCCAAAATTACCCTGTGCCAATTAGGATGATTGGGATTAATGGGTTT
GGTAGGTCAGGTAGATCAACCAGGCAGTTAATGGAGTACATTGGTTTAACACATAGGAGGATTGTTAATGAGGCTCTCAC
GCTAATTAAGGGTGAGTAA

Upstream 100 bases:

>100_bases
TATTAAGCCTCATTTTTAGATTAATGAAGTGAATCCTGAGTAACCCTACTGATTACTCATGATGCACCTCAGTTAACTAT
AAATTATTAAATTATGGGTA

Downstream 100 bases:

>100_bases
TAATGCTGTGGCAGTTGAGGAAGAGTATTGATGAGGTTGATGATGAAATAATTAAGTTACTCGCCAGGAGGCTAACCATA
GCCGAAACCATAGGTGATGT

Product: transketolase central region

Products: NA

Alternate protein names: TK [H]

Number of amino acids: Translated: 592; Mature: 592

Protein sequence:

>592_residues
MLKNIDCIGCLDWYGIRDPRGIPGMVKEAKVNLVNRVKEISNKARSILVGLSLIDPHIHLGSSLSSIDIIATLYLMTNVR
DNDPLRRDYVILSKGHAAPALYVVLSELGLVNREELMMINEPWSPLQGHPEVKLPTVPVSTGSLAQGLSTAVGIARGLMA
REASGKVFVIVGDGELDEGQAWEALMDIAESKLSNLFIIIDYNGVQLDGPVRGIKSTLTEALKSLGFTVLECDGHDPEAL
IDTLIQAHKVNGPKVIVARTIRGKGVSDIEGTSKQRILDDGGEPGFGSMRDAVGRALLEAGERYNDLYVVTADVGGSTRA
IWFKEKFPNRYIDVGIAEQHMIGVASGLALTGLRPVAIGFAMFIMRAWEQVRNTVSRMNLNVKIIGTHSGLSDYADGASH
QTFEDISLMRTLPNMTIVVPADPNEAGKAVLALMEHQGPAYVRIGRDYGPRVTNGDEFKLGKASVLRDGDDLAIIGAGPV
LWDALMAAEELGKMGVSVMVINLSTIKPIDVDTVVKAAKRTGAVLTIEEHSTHGGVGSAVAEVLSQNYPVPIRMIGINGF
GRSGRSTRQLMEYIGLTHRRIVNEALTLIKGE

Sequences:

>Translated_592_residues
MLKNIDCIGCLDWYGIRDPRGIPGMVKEAKVNLVNRVKEISNKARSILVGLSLIDPHIHLGSSLSSIDIIATLYLMTNVR
DNDPLRRDYVILSKGHAAPALYVVLSELGLVNREELMMINEPWSPLQGHPEVKLPTVPVSTGSLAQGLSTAVGIARGLMA
REASGKVFVIVGDGELDEGQAWEALMDIAESKLSNLFIIIDYNGVQLDGPVRGIKSTLTEALKSLGFTVLECDGHDPEAL
IDTLIQAHKVNGPKVIVARTIRGKGVSDIEGTSKQRILDDGGEPGFGSMRDAVGRALLEAGERYNDLYVVTADVGGSTRA
IWFKEKFPNRYIDVGIAEQHMIGVASGLALTGLRPVAIGFAMFIMRAWEQVRNTVSRMNLNVKIIGTHSGLSDYADGASH
QTFEDISLMRTLPNMTIVVPADPNEAGKAVLALMEHQGPAYVRIGRDYGPRVTNGDEFKLGKASVLRDGDDLAIIGAGPV
LWDALMAAEELGKMGVSVMVINLSTIKPIDVDTVVKAAKRTGAVLTIEEHSTHGGVGSAVAEVLSQNYPVPIRMIGINGF
GRSGRSTRQLMEYIGLTHRRIVNEALTLIKGE
>Mature_592_residues
MLKNIDCIGCLDWYGIRDPRGIPGMVKEAKVNLVNRVKEISNKARSILVGLSLIDPHIHLGSSLSSIDIIATLYLMTNVR
DNDPLRRDYVILSKGHAAPALYVVLSELGLVNREELMMINEPWSPLQGHPEVKLPTVPVSTGSLAQGLSTAVGIARGLMA
REASGKVFVIVGDGELDEGQAWEALMDIAESKLSNLFIIIDYNGVQLDGPVRGIKSTLTEALKSLGFTVLECDGHDPEAL
IDTLIQAHKVNGPKVIVARTIRGKGVSDIEGTSKQRILDDGGEPGFGSMRDAVGRALLEAGERYNDLYVVTADVGGSTRA
IWFKEKFPNRYIDVGIAEQHMIGVASGLALTGLRPVAIGFAMFIMRAWEQVRNTVSRMNLNVKIIGTHSGLSDYADGASH
QTFEDISLMRTLPNMTIVVPADPNEAGKAVLALMEHQGPAYVRIGRDYGPRVTNGDEFKLGKASVLRDGDDLAIIGAGPV
LWDALMAAEELGKMGVSVMVINLSTIKPIDVDTVVKAAKRTGAVLTIEEHSTHGGVGSAVAEVLSQNYPVPIRMIGINGF
GRSGRSTRQLMEYIGLTHRRIVNEALTLIKGE

Specific function: Catalyzes The Acyloin Condensation Reaction Between C Atoms 2 And 3 Of Pyruvate And Glyceraldehyde 3-Phosphate To Yield 1-Deoxy-D-Xylulose-5-Phosphate (Dxp). [C]

COG id: COG3958

COG function: function code G; Transketolase, C-terminal subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transketolase family [H]

Homologues:

Organism=Homo sapiens, GI133778974, Length=632, Percent_Identity=31.6455696202532, Blast_Score=271, Evalue=1e-72,
Organism=Homo sapiens, GI205277463, Length=611, Percent_Identity=31.0965630114566, Blast_Score=261, Evalue=1e-69,
Organism=Homo sapiens, GI4507521, Length=611, Percent_Identity=31.0965630114566, Blast_Score=261, Evalue=1e-69,
Organism=Homo sapiens, GI225637461, Length=511, Percent_Identity=32.8767123287671, Blast_Score=233, Evalue=3e-61,
Organism=Homo sapiens, GI225637463, Length=511, Percent_Identity=32.8767123287671, Blast_Score=233, Evalue=3e-61,
Organism=Homo sapiens, GI225637459, Length=511, Percent_Identity=32.8767123287671, Blast_Score=233, Evalue=4e-61,
Organism=Homo sapiens, GI291084858, Length=269, Percent_Identity=24.907063197026, Blast_Score=82, Evalue=1e-15,
Organism=Homo sapiens, GI4557353, Length=255, Percent_Identity=25.8823529411765, Blast_Score=80, Evalue=4e-15,
Organism=Homo sapiens, GI34101272, Length=255, Percent_Identity=25.8823529411765, Blast_Score=80, Evalue=4e-15,
Organism=Escherichia coli, GI1786622, Length=584, Percent_Identity=26.7123287671233, Blast_Score=172, Evalue=6e-44,
Organism=Escherichia coli, GI1788808, Length=255, Percent_Identity=30.9803921568627, Blast_Score=92, Evalue=7e-20,
Organism=Escherichia coli, GI48994911, Length=253, Percent_Identity=28.8537549407115, Blast_Score=77, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17539652, Length=608, Percent_Identity=30.4276315789474, Blast_Score=253, Evalue=3e-67,
Organism=Caenorhabditis elegans, GI17538422, Length=274, Percent_Identity=25.5474452554745, Blast_Score=84, Evalue=2e-16,
Organism=Saccharomyces cerevisiae, GI6319698, Length=278, Percent_Identity=27.3381294964029, Blast_Score=82, Evalue=3e-16,
Organism=Saccharomyces cerevisiae, GI6325331, Length=203, Percent_Identity=32.0197044334975, Blast_Score=76, Evalue=2e-14,
Organism=Saccharomyces cerevisiae, GI6319593, Length=206, Percent_Identity=29.6116504854369, Blast_Score=73, Evalue=1e-13,
Organism=Drosophila melanogaster, GI45551847, Length=629, Percent_Identity=30.6836248012719, Blast_Score=241, Evalue=1e-63,
Organism=Drosophila melanogaster, GI45550715, Length=629, Percent_Identity=30.6836248012719, Blast_Score=241, Evalue=1e-63,
Organism=Drosophila melanogaster, GI24645119, Length=571, Percent_Identity=31.6987740805604, Blast_Score=236, Evalue=4e-62,
Organism=Drosophila melanogaster, GI24666278, Length=619, Percent_Identity=30.5331179321486, Blast_Score=235, Evalue=8e-62,
Organism=Drosophila melanogaster, GI21358145, Length=281, Percent_Identity=26.3345195729537, Blast_Score=83, Evalue=7e-16,
Organism=Drosophila melanogaster, GI24650940, Length=281, Percent_Identity=26.3345195729537, Blast_Score=83, Evalue=7e-16,
Organism=Drosophila melanogaster, GI160714828, Length=279, Percent_Identity=25.4480286738351, Blast_Score=70, Evalue=4e-12,
Organism=Drosophila melanogaster, GI160714832, Length=279, Percent_Identity=25.4480286738351, Blast_Score=70, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009014
- InterPro:   IPR015941
- InterPro:   IPR005475
- InterPro:   IPR020826
- InterPro:   IPR005476 [H]

Pfam domain/function: PF02779 Transket_pyr; PF02780 Transketolase_C [H]

EC number: =2.2.1.1 [H]

Molecular weight: Translated: 63847; Mature: 63847

Theoretical pI: Translated: 6.34; Mature: 6.34

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLKNIDCIGCLDWYGIRDPRGIPGMVKEAKVNLVNRVKEISNKARSILVGLSLIDPHIHL
CCCCCCEEEEHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHEEEEHHHCCCCCCC
GSSLSSIDIIATLYLMTNVRDNDPLRRDYVILSKGHAAPALYVVLSELGLVNREELMMIN
CCCCCHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHCCCCCCCEEEEC
EPWSPLQGHPEVKLPTVPVSTGSLAQGLSTAVGIARGLMAREASGKVFVIVGDGELDEGQ
CCCCCCCCCCCEECCEECCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCH
AWEALMDIAESKLSNLFIIIDYNGVQLDGPVRGIKSTLTEALKSLGFTVLECDGHDPEAL
HHHHHHHHHHHHHCCEEEEEECCCEEECCHHHHHHHHHHHHHHHCCCEEEEECCCCHHHH
IDTLIQAHKVNGPKVIVARTIRGKGVSDIEGTSKQRILDDGGEPGFGSMRDAVGRALLEA
HHHHHHHHCCCCCEEEEEEEECCCCCCCCCCCCHHHHHCCCCCCCCCHHHHHHHHHHHHC
GERYNDLYVVTADVGGSTRAIWFKEKFPNRYIDVGIAEQHMIGVASGLALTGLRPVAIGF
CCCCCEEEEEEECCCCCEEEEEEHHHCCCCEEECCCCHHHHHHHHCCHHHCCCHHHHHHH
AMFIMRAWEQVRNTVSRMNLNVKIIGTHSGLSDYADGASHQTFEDISLMRTLPNMTIVVP
HHHHHHHHHHHHHHHHHCCCEEEEEEECCCCHHHCCCCCCCHHHHHHHHHHCCCCEEEEE
ADPNEAGKAVLALMEHQGPAYVRIGRDYGPRVTNGDEFKLGKASVLRDGDDLAIIGAGPV
CCCCHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCEECCCHHHEECCCCEEEEECCHH
LWDALMAAEELGKMGVSVMVINLSTIKPIDVDTVVKAAKRTGAVLTIEEHSTHGGVGSAV
HHHHHHHHHHHHCCCEEEEEEEECCCCCCCHHHHHHHHHHCCCEEEEECCCCCCCHHHHH
AEVLSQNYPVPIRMIGINGFGRSGRSTRQLMEYIGLTHRRIVNEALTLIKGE
HHHHHCCCCCEEEEEEECCCCCCCCHHHHHHHHHCHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MLKNIDCIGCLDWYGIRDPRGIPGMVKEAKVNLVNRVKEISNKARSILVGLSLIDPHIHL
CCCCCCEEEEHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHEEEEHHHCCCCCCC
GSSLSSIDIIATLYLMTNVRDNDPLRRDYVILSKGHAAPALYVVLSELGLVNREELMMIN
CCCCCHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHCCCCCCCEEEEC
EPWSPLQGHPEVKLPTVPVSTGSLAQGLSTAVGIARGLMAREASGKVFVIVGDGELDEGQ
CCCCCCCCCCCEECCEECCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCH
AWEALMDIAESKLSNLFIIIDYNGVQLDGPVRGIKSTLTEALKSLGFTVLECDGHDPEAL
HHHHHHHHHHHHHCCEEEEEECCCEEECCHHHHHHHHHHHHHHHCCCEEEEECCCCHHHH
IDTLIQAHKVNGPKVIVARTIRGKGVSDIEGTSKQRILDDGGEPGFGSMRDAVGRALLEA
HHHHHHHHCCCCCEEEEEEEECCCCCCCCCCCCHHHHHCCCCCCCCCHHHHHHHHHHHHC
GERYNDLYVVTADVGGSTRAIWFKEKFPNRYIDVGIAEQHMIGVASGLALTGLRPVAIGF
CCCCCEEEEEEECCCCCEEEEEEHHHCCCCEEECCCCHHHHHHHHCCHHHCCCHHHHHHH
AMFIMRAWEQVRNTVSRMNLNVKIIGTHSGLSDYADGASHQTFEDISLMRTLPNMTIVVP
HHHHHHHHHHHHHHHHHCCCEEEEEEECCCCHHHCCCCCCCHHHHHHHHHHCCCCEEEEE
ADPNEAGKAVLALMEHQGPAYVRIGRDYGPRVTNGDEFKLGKASVLRDGDDLAIIGAGPV
CCCCHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCEECCCHHHEECCCCEEEEECCHH
LWDALMAAEELGKMGVSVMVINLSTIKPIDVDTVVKAAKRTGAVLTIEEHSTHGGVGSAV
HHHHHHHHHHHHCCCEEEEEEEECCCCCCCHHHHHHHHHHCCCEEEEECCCCCCCHHHHH
AEVLSQNYPVPIRMIGINGFGRSGRSTRQLMEYIGLTHRRIVNEALTLIKGE
HHHHHCCCCCEEEEEEECCCCCCCCHHHHHHHHHCHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]