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The map label for this gene is aroB [H]

Identifier: 159041379

GI number: 159041379

Start: 841405

End: 842457

Strand: Reverse

Name: aroB [H]

Synonym: Cmaq_0806

Alternate gene names: 159041379

Gene position: 842457-841405 (Counterclockwise)

Preceding gene: 159041380

Following gene: 159041378

Centisome position: 40.55

GC content: 42.36

Gene sequence:

>1053_bases
ATGAGGAGCTTCACTTATAGGAGTAGGTGTAGTGGTGAGGTAAGGGTTCTGGTTAATTACCCGCATGCCGATGAGTTAAG
TAAACTCCTTGATAAGTACACTAGCTGCATGATAATTACACCATCCTCCGTAAGCAGTTTAGTGAATTTCAGTAAATGCC
CAAGGATTATTATTAAGGATGGGGAAGAGGGTAAGGGCATTGAAACAGTCTTAAACATTATTAAGCAATCAATGGATAAT
TCCCTGGATAGGAGCGGGGTTATGATTGGGATTGGGGGTGGAAGCACACTTGATGTAACTGGGTTTGCTGCAGCAGTGTA
CATGAGGGGTGTGGATTACGTTAATGTACCCACCACTACATTAGCCATGGTTGATGCAGCCCTGGGGGGAAAAACAGGGG
TTAATGCCGCTGGTTTAAAGAATATTATTGGTGTAGTGAAGCAGCCCAGTGAAATCATAGTGGATTTAGCCTTCATTAAA
TCCCTACCAGCCTCAAATTACCTGGATGGTTTCGCTGAGGTTCTTAAGTATGGGGTAACTATGGATAAGGGGTTATTCGA
TAAGTTAAGCAGTAATGTTGATAAGGTGATGAATAGGGATGAGGGATTACTGGAGGATTTAATCTACGGTTCACTGGTTA
ATAAGGCTCATGTGGTTGAGGCTGATGAGTACGATACCCTAGGTATAAGAATAGTGCTTAACTATGGGCATACTATTGGA
CACGCATTAGAGTCAGCGTCAGGATTCAGCATCAGTCACGGTAAAGCAGTGGGGTTAGGCATGATTTGTGAATCAACCAT
TGGGGTTAAATTAGGTTACACGAACCCAGATATACCCGGTTACTTAACTGAATCACTAAGTGAACTTAACTTGATTCAAA
GCATTAAGGTTAACGCTGATTCCGCATTAAGAGCCATTACCGGTGATAAGAAGAGAAACGGTGGCTTCCTTAACTTACCC
ATTGTTACTGAATTAGGTGATTGGGTTAAGGTTAGGGTTAAGGTTGATGAGTACCTTAGGCTGGTGAAGGAGTCATGCAT
GTATTTGGCTTAA

Upstream 100 bases:

>100_bases
GGGAGGCTTTATCAGACTCCGAGCAGCAATTAACCTTCGATATGTTTAATGAATTAATGAGTAAGGCTAAGGCAGTAGCC
CAGGCAATAGGTAGGGGTAT

Downstream 100 bases:

>100_bases
TAGGTTATCCACTGAACTATACCCTATCACCTCAGATTCATAACTACGTCTTCAAGAGACTAAGAATTGATGCAGCGTAT
GTACCATTAAGGGTAGCGTC

Product: 3-dehydroquinate synthase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 350; Mature: 350

Protein sequence:

>350_residues
MRSFTYRSRCSGEVRVLVNYPHADELSKLLDKYTSCMIITPSSVSSLVNFSKCPRIIIKDGEEGKGIETVLNIIKQSMDN
SLDRSGVMIGIGGGSTLDVTGFAAAVYMRGVDYVNVPTTTLAMVDAALGGKTGVNAAGLKNIIGVVKQPSEIIVDLAFIK
SLPASNYLDGFAEVLKYGVTMDKGLFDKLSSNVDKVMNRDEGLLEDLIYGSLVNKAHVVEADEYDTLGIRIVLNYGHTIG
HALESASGFSISHGKAVGLGMICESTIGVKLGYTNPDIPGYLTESLSELNLIQSIKVNADSALRAITGDKKRNGGFLNLP
IVTELGDWVKVRVKVDEYLRLVKESCMYLA

Sequences:

>Translated_350_residues
MRSFTYRSRCSGEVRVLVNYPHADELSKLLDKYTSCMIITPSSVSSLVNFSKCPRIIIKDGEEGKGIETVLNIIKQSMDN
SLDRSGVMIGIGGGSTLDVTGFAAAVYMRGVDYVNVPTTTLAMVDAALGGKTGVNAAGLKNIIGVVKQPSEIIVDLAFIK
SLPASNYLDGFAEVLKYGVTMDKGLFDKLSSNVDKVMNRDEGLLEDLIYGSLVNKAHVVEADEYDTLGIRIVLNYGHTIG
HALESASGFSISHGKAVGLGMICESTIGVKLGYTNPDIPGYLTESLSELNLIQSIKVNADSALRAITGDKKRNGGFLNLP
IVTELGDWVKVRVKVDEYLRLVKESCMYLA
>Mature_350_residues
MRSFTYRSRCSGEVRVLVNYPHADELSKLLDKYTSCMIITPSSVSSLVNFSKCPRIIIKDGEEGKGIETVLNIIKQSMDN
SLDRSGVMIGIGGGSTLDVTGFAAAVYMRGVDYVNVPTTTLAMVDAALGGKTGVNAAGLKNIIGVVKQPSEIIVDLAFIK
SLPASNYLDGFAEVLKYGVTMDKGLFDKLSSNVDKVMNRDEGLLEDLIYGSLVNKAHVVEADEYDTLGIRIVLNYGHTIG
HALESASGFSISHGKAVGLGMICESTIGVKLGYTNPDIPGYLTESLSELNLIQSIKVNADSALRAITGDKKRNGGFLNLP
IVTELGDWVKVRVKVDEYLRLVKESCMYLA

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; second step. [C]

COG id: COG0337

COG function: function code E; 3-dehydroquinate synthetase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dehydroquinate synthase family [H]

Homologues:

Organism=Escherichia coli, GI1789791, Length=194, Percent_Identity=40.7216494845361, Blast_Score=155, Evalue=5e-39,
Organism=Saccharomyces cerevisiae, GI6320332, Length=341, Percent_Identity=30.4985337243402, Blast_Score=140, Evalue=4e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016303
- InterPro:   IPR002658
- InterPro:   IPR016037 [H]

Pfam domain/function: PF01761 DHQ_synthase [H]

EC number: =4.2.3.4 [H]

Molecular weight: Translated: 37747; Mature: 37747

Theoretical pI: Translated: 6.06; Mature: 6.06

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRSFTYRSRCSGEVRVLVNYPHADELSKLLDKYTSCMIITPSSVSSLVNFSKCPRIIIKD
CCCCCCCCCCCCCEEEEEECCCHHHHHHHHHHHCCEEEECCHHHHHHHHHHHCCEEEEEC
GEEGKGIETVLNIIKQSMDNSLDRSGVMIGIGGGSTLDVTGFAAAVYMRGVDYVNVPTTT
CCCCCCHHHHHHHHHHHHCCCCCCCCEEEEECCCCEEEHHHHHHHHHHHCCCEECCCHHH
LAMVDAALGGKTGVNAAGLKNIIGVVKQPSEIIVDLAFIKSLPASNYLDGFAEVLKYGVT
HHHHHHHCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCC
MDKGLFDKLSSNVDKVMNRDEGLLEDLIYGSLVNKAHVVEADEYDTLGIRIVLNYGHTIG
CCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCEEEECCCCCCEEEEEEEECCCHHH
HALESASGFSISHGKAVGLGMICESTIGVKLGYTNPDIPGYLTESLSELNLIQSIKVNAD
HHHHCCCCCEECCCCEEEHHHHHHCCCCEEECCCCCCCCHHHHHHHHHHHHHHHHCCCCH
SALRAITGDKKRNGGFLNLPIVTELGDWVKVRVKVDEYLRLVKESCMYLA
HHHHHHCCCCCCCCCEEECCHHHHCCCEEEEEEEHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MRSFTYRSRCSGEVRVLVNYPHADELSKLLDKYTSCMIITPSSVSSLVNFSKCPRIIIKD
CCCCCCCCCCCCCEEEEEECCCHHHHHHHHHHHCCEEEECCHHHHHHHHHHHCCEEEEEC
GEEGKGIETVLNIIKQSMDNSLDRSGVMIGIGGGSTLDVTGFAAAVYMRGVDYVNVPTTT
CCCCCCHHHHHHHHHHHHCCCCCCCCEEEEECCCCEEEHHHHHHHHHHHCCCEECCCHHH
LAMVDAALGGKTGVNAAGLKNIIGVVKQPSEIIVDLAFIKSLPASNYLDGFAEVLKYGVT
HHHHHHHCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCC
MDKGLFDKLSSNVDKVMNRDEGLLEDLIYGSLVNKAHVVEADEYDTLGIRIVLNYGHTIG
CCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCEEEECCCCCCEEEEEEEECCCHHH
HALESASGFSISHGKAVGLGMICESTIGVKLGYTNPDIPGYLTESLSELNLIQSIKVNAD
HHHHCCCCCEECCCCEEEHHHHHHCCCCEEECCCCCCCCHHHHHHHHHHHHHHHHCCCCH
SALRAITGDKKRNGGFLNLPIVTELGDWVKVRVKVDEYLRLVKESCMYLA
HHHHHHCCCCCCCCCEEECCHHHHCCCEEEEEEEHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11572479 [H]