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The map label for this gene is 159041369

Identifier: 159041369

GI number: 159041369

Start: 830279

End: 830686

Strand: Reverse

Name: 159041369

Synonym: Cmaq_0796

Alternate gene names: NA

Gene position: 830686-830279 (Counterclockwise)

Preceding gene: 159041370

Following gene: 159041367

Centisome position: 39.98

GC content: 43.14

Gene sequence:

>408_bases
ATGAAAATACCTGGTGTTGAGTATAAGACCCTATGCAGATACTGTAGCCTGAGTAATGAATTACTGATAGCGGAGGAGAG
CGGCTACGGTATCTATGCTTATGATGAACCCTTCAATAATGGGCACATAGTCATAGTGCCTAGGAGGCATGTATCCTTAA
GTGAATTAAGTGTTGAGGAATTGTATAAGGCTCTTAGGCTTGTTAAGAGGGCTGAGGCTACTTTAAGGAGTGTGTATCAT
CCGCAGGGCCTTAACATTGGATTAGTCGCTTATCCACATGTTGCCTTCCATATAGTTCCTAGGTGGGGTGGTGATGTCAG
CTTCATTAAGGTTTTCTTTAACGCTAAACCAATTCCAGAAACACCCATTCAGTACGCTGAACGCTTGAGAAGGGCTTGGA
GAAGTTAA

Upstream 100 bases:

>100_bases
ATTGCCCAAGCAGCCCAAGTCACTGAGGTTACTGTTAGGAATAGGTATAAGGAGCTTGCTAAGGAGTTAAACATAAAGAT
ACCGATTAAGTAACTTACTC

Downstream 100 bases:

>100_bases
CCCACAGGGTACTTAGGCACCACTTCATAAATAACCATAACCCTCTCGTAGTCGCTTGATAAGTTATCAAGGTTACTTAA
TTGCCTAATTTCAATAAGCT

Product: diadenosine tetraphosphate (Ap4A) hydrolase-like protein

Products: NA

Alternate protein names: ATP adenylyltransferase; Diadenosine 5',5'''-P1,P4-tetraphosphate phosphorylase; AP,A phosphorylase [H]

Number of amino acids: Translated: 135; Mature: 135

Protein sequence:

>135_residues
MKIPGVEYKTLCRYCSLSNELLIAEESGYGIYAYDEPFNNGHIVIVPRRHVSLSELSVEELYKALRLVKRAEATLRSVYH
PQGLNIGLVAYPHVAFHIVPRWGGDVSFIKVFFNAKPIPETPIQYAERLRRAWRS

Sequences:

>Translated_135_residues
MKIPGVEYKTLCRYCSLSNELLIAEESGYGIYAYDEPFNNGHIVIVPRRHVSLSELSVEELYKALRLVKRAEATLRSVYH
PQGLNIGLVAYPHVAFHIVPRWGGDVSFIKVFFNAKPIPETPIQYAERLRRAWRS
>Mature_135_residues
MKIPGVEYKTLCRYCSLSNELLIAEESGYGIYAYDEPFNNGHIVIVPRRHVSLSELSVEELYKALRLVKRAEATLRSVYH
PQGLNIGLVAYPHVAFHIVPRWGGDVSFIKVFFNAKPIPETPIQYAERLRRAWRS

Specific function: Catabolizes diadenosine 5',5'''-P1,P4-tetraphosphate (Ap4A) into ADP and ATP. It does not catalyze the reverse phosphorolysis reaction. The optimum substrates are dinucleoside polyphosphates containing four or five phosphate residues [H]

COG id: COG0537

COG function: function code FGR; Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HIT domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011146
- InterPro:   IPR011151
- InterPro:   IPR001310 [H]

Pfam domain/function: PF01230 HIT [H]

EC number: =2.7.7.53 [H]

Molecular weight: Translated: 15503; Mature: 15503

Theoretical pI: Translated: 9.31; Mature: 9.31

Prosite motif: PS51084 HIT_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIPGVEYKTLCRYCSLSNELLIAEESGYGIYAYDEPFNNGHIVIVPRRHVSLSELSVEE
CCCCCCCHHHHHHHHCCCCCEEEEECCCCEEEEECCCCCCCEEEEEECCCCCHHHCCHHH
LYKALRLVKRAEATLRSVYHPQGLNIGLVAYPHVAFHIVPRWGGDVSFIKVFFNAKPIPE
HHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCEEEEEEECCCCCEEEEEEEECCCCCCC
TPIQYAERLRRAWRS
CHHHHHHHHHHHHCC
>Mature Secondary Structure
MKIPGVEYKTLCRYCSLSNELLIAEESGYGIYAYDEPFNNGHIVIVPRRHVSLSELSVEE
CCCCCCCHHHHHHHHCCCCCEEEEECCCCEEEEECCCCCCCEEEEEECCCCCHHHCCHHH
LYKALRLVKRAEATLRSVYHPQGLNIGLVAYPHVAFHIVPRWGGDVSFIKVFFNAKPIPE
HHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCEEEEEEECCCCCEEEEEEEECCCCCCC
TPIQYAERLRRAWRS
CHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230; 12368430; 12218036 [H]