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The map label for this gene is eif2b [H]

Identifier: 159041161

GI number: 159041161

Start: 612369

End: 612779

Strand: Reverse

Name: eif2b [H]

Synonym: Cmaq_0582

Alternate gene names: 159041161

Gene position: 612779-612369 (Counterclockwise)

Preceding gene: 159041162

Following gene: 159041157

Centisome position: 29.5

GC content: 44.04

Gene sequence:

>411_bases
ATGTCGGTTGATCCAACTTACCTTAAGCTACTTGAGAGGGCTTACAAGATAGTGACACCTAAGGTTGAGAGGAGGAGGGA
GATACCTAAGCTTAGTGTTGAAATTGAACCCAGGAGGACTATGATTAGGAACTTTAAGGATATAGCCGATAGGTTGAATA
GGGATGTTACGCATATGGCTAGGTTCTTCATTAAGGAATTAGCTGTACCAGGTAATGTTGACTCTAATGGATCCCTAGTA
ATCTATGCTGAACGCACTCCAAGAACCCTTGAGGCGGTTTACGATAGGTACATTAAACTTTACGTAACATGCCCGGTCTG
CGGCTCCATAGATACATACCTTGTTAAAGAGGATAGAATATACGTACTTGTCTGCACAGCCTGTGGAGCCAGGACTCCTA
GAAGGGCCTAG

Upstream 100 bases:

>100_bases
ATGATTGACGCAGCCTATATTAAGGAGGTATGTATGGTAAGGTAACTGATAATTAAGTGATTCCTATACACTTATAAGTG
GGTACTGTGGGGTTGGGTTA

Downstream 100 bases:

>100_bases
GATTATTTATCGCTGAAGTGGATTTAATTATGGGTATTCACCGCCCTTAATGCCGTGTCCTCGAAGGTTATGGGTTTACC
ATGTGGGCAGGAGCTTGGCT

Product: translation initiation factor IF-2 subunit beta

Products: NA

Alternate protein names: aIF2-beta; eIF-2-beta [H]

Number of amino acids: Translated: 136; Mature: 135

Protein sequence:

>136_residues
MSVDPTYLKLLERAYKIVTPKVERRREIPKLSVEIEPRRTMIRNFKDIADRLNRDVTHMARFFIKELAVPGNVDSNGSLV
IYAERTPRTLEAVYDRYIKLYVTCPVCGSIDTYLVKEDRIYVLVCTACGARTPRRA

Sequences:

>Translated_136_residues
MSVDPTYLKLLERAYKIVTPKVERRREIPKLSVEIEPRRTMIRNFKDIADRLNRDVTHMARFFIKELAVPGNVDSNGSLV
IYAERTPRTLEAVYDRYIKLYVTCPVCGSIDTYLVKEDRIYVLVCTACGARTPRRA
>Mature_135_residues
SVDPTYLKLLERAYKIVTPKVERRREIPKLSVEIEPRRTMIRNFKDIADRLNRDVTHMARFFIKELAVPGNVDSNGSLVI
YAERTPRTLEAVYDRYIKLYVTCPVCGSIDTYLVKEDRIYVLVCTACGARTPRRA

Specific function: eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA [H]

COG id: COG1601

COG function: function code J; Translation initiation factor 2, beta subunit (eIF-2beta)/eIF-5 N-terminal domain

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the eIF-2-beta/eIF-5 family [H]

Homologues:

Organism=Homo sapiens, GI29826335, Length=136, Percent_Identity=37.5, Blast_Score=86, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17508049, Length=95, Percent_Identity=33.6842105263158, Blast_Score=74, Evalue=2e-14,
Organism=Saccharomyces cerevisiae, GI6325018, Length=134, Percent_Identity=33.5820895522388, Blast_Score=83, Evalue=1e-17,
Organism=Drosophila melanogaster, GI17647377, Length=136, Percent_Identity=36.0294117647059, Blast_Score=87, Evalue=3e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004458
- InterPro:   IPR002735
- InterPro:   IPR016189
- InterPro:   IPR016190 [H]

Pfam domain/function: PF01873 eIF-5_eIF-2B [H]

EC number: NA

Molecular weight: Translated: 15784; Mature: 15652

Theoretical pI: Translated: 9.77; Mature: 9.77

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.9 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
3.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVDPTYLKLLERAYKIVTPKVERRREIPKLSVEIEPRRTMIRNFKDIADRLNRDVTHMA
CCCCHHHHHHHHHHHHHCCCCHHHHHCCCCEEEEECHHHHHHHHHHHHHHHHCCCHHHHH
RFFIKELAVPGNVDSNGSLVIYAERTPRTLEAVYDRYIKLYVTCPVCGSIDTYLVKEDRI
HHHHHHHCCCCCCCCCCCEEEEECCCCHHHHHHHHHHEEEEEECCCCCCCCCEEEECCCE
YVLVCTACGARTPRRA
EEEEEECCCCCCCCCC
>Mature Secondary Structure 
SVDPTYLKLLERAYKIVTPKVERRREIPKLSVEIEPRRTMIRNFKDIADRLNRDVTHMA
CCCHHHHHHHHHHHHHCCCCHHHHHCCCCEEEEECHHHHHHHHHHHHHHHHCCCHHHHH
RFFIKELAVPGNVDSNGSLVIYAERTPRTLEAVYDRYIKLYVTCPVCGSIDTYLVKEDRI
HHHHHHHCCCCCCCCCCCEEEEECCCCHHHHHHHHHHEEEEEECCCCCCCCCEEEECCCE
YVLVCTACGARTPRRA
EEEEEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11792869 [H]