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The map label for this gene is etfA [H]

Identifier: 159041059

GI number: 159041059

Start: 514859

End: 515911

Strand: Reverse

Name: etfA [H]

Synonym: Cmaq_0476

Alternate gene names: 159041059

Gene position: 515911-514859 (Counterclockwise)

Preceding gene: 159041060

Following gene: 159041058

Centisome position: 24.83

GC content: 46.53

Gene sequence:

>1053_bases
ATGAGTAGTGCAAGAATATGCCCAGAGTGGCCTCAGGTAAATAAGAGTGAGTATAAGGGTATTTGGGTTTACATTGAGCA
TCAGAATGGTGTAATAAAGGACGGTAGCCTCCAGTTGATTGGTAAGGCTAGGGAATTAGCCGCGAAGATTAATGTGGATG
TCTCAGCAGTAATGATTGGACATAACCTAGGGGATTTGGTTAAGGAACCAATATACTATGGGGCGGATAGGGTTATTTAC
ATTGATGATGAGGCCCTATCAGTCTACATACCTCACCTCTACGCCTCAGTAATAGTTAACCTTGTTAATAAGTATAAGCC
TGAGGTGGTTTTATTCGCAGCAACAAAGAGGGGGAGGGAGTTAGCCCCATACGTTGCTAACACCCTTAGAGCCGGTATAA
CCGCTGACTGCACTGACTTAGACATTGACGTTAAGACGAGGGATCTTGATCAAGTTAGGCCAACATATGGAGGCAATATA
CTAGCCCACATTAGGACACCCAACAGGAGGCCTCAATTAGCGAGCGTTAGGCCTAACGTATTCCCAACACCACCAAGGGA
CACTAACCGTAAGGGTGAGGTTATTAGGGAGTCCCTGGATAAATTACCTAAGCCCAATGGTTCATTACTGGGTGTTAAAC
CAGTAATTAAGGGGGATAGTGACTTACCACCAGTGGAGAAGGCTGACCTAGTGGTTGTGGCTGGGAGGGGTGTGGCTGGG
CCTGAGGGTGTTAAGCTGCTTATTGAGTTGGCTAAGGCCCTTGGAGGCACTATTGGCGGTAGTAAGAAGGTTACTGATGC
TGGTTGGTTACCTGCTGATAGGCAGATTGGGCAAACCGGTAAGACGATTAGGCCCACTGTGTATATTGGTGTTGGTGTCA
GTGGGGCTATTCAGCACATTTTCGGTATGAAGGAGTCTAAGATAATAGTCGCCATTAACAGTGACCCCAATGCCCCAATC
TTCGAGTACGCTGACTACGGCATAGTTGGTGATTATAGGCAGGTGGTTCAGGCATTGCTTGAGACCTTAAGTTCAATGAG
GAAGACTAATTGA

Upstream 100 bases:

>100_bases
CTAAGCCAATACCTAGGAAGAAGCAGATATTCAAGGGTGATCCAAGGGAGGCGGCTAAGTGGCTTATTGAGAACTTAACC
AAGGAGGGGGTGATTAGGCT

Downstream 100 bases:

>100_bases
AGGATTAATCCTCAAAGCGAATCAACGCTTAAGGTTTATTTACTTAATCACCTTTAAAGGGATTCATGGAGAGTTTAGAG
GGTTTAAGCAGTTATGCTGA

Product: electron transfer flavoprotein subunit alpha

Products: NA

Alternate protein names: Alpha-ETF; Electron transfer flavoprotein large subunit; ETFLS [H]

Number of amino acids: Translated: 350; Mature: 349

Protein sequence:

>350_residues
MSSARICPEWPQVNKSEYKGIWVYIEHQNGVIKDGSLQLIGKARELAAKINVDVSAVMIGHNLGDLVKEPIYYGADRVIY
IDDEALSVYIPHLYASVIVNLVNKYKPEVVLFAATKRGRELAPYVANTLRAGITADCTDLDIDVKTRDLDQVRPTYGGNI
LAHIRTPNRRPQLASVRPNVFPTPPRDTNRKGEVIRESLDKLPKPNGSLLGVKPVIKGDSDLPPVEKADLVVVAGRGVAG
PEGVKLLIELAKALGGTIGGSKKVTDAGWLPADRQIGQTGKTIRPTVYIGVGVSGAIQHIFGMKESKIIVAINSDPNAPI
FEYADYGIVGDYRQVVQALLETLSSMRKTN

Sequences:

>Translated_350_residues
MSSARICPEWPQVNKSEYKGIWVYIEHQNGVIKDGSLQLIGKARELAAKINVDVSAVMIGHNLGDLVKEPIYYGADRVIY
IDDEALSVYIPHLYASVIVNLVNKYKPEVVLFAATKRGRELAPYVANTLRAGITADCTDLDIDVKTRDLDQVRPTYGGNI
LAHIRTPNRRPQLASVRPNVFPTPPRDTNRKGEVIRESLDKLPKPNGSLLGVKPVIKGDSDLPPVEKADLVVVAGRGVAG
PEGVKLLIELAKALGGTIGGSKKVTDAGWLPADRQIGQTGKTIRPTVYIGVGVSGAIQHIFGMKESKIIVAINSDPNAPI
FEYADYGIVGDYRQVVQALLETLSSMRKTN
>Mature_349_residues
SSARICPEWPQVNKSEYKGIWVYIEHQNGVIKDGSLQLIGKARELAAKINVDVSAVMIGHNLGDLVKEPIYYGADRVIYI
DDEALSVYIPHLYASVIVNLVNKYKPEVVLFAATKRGRELAPYVANTLRAGITADCTDLDIDVKTRDLDQVRPTYGGNIL
AHIRTPNRRPQLASVRPNVFPTPPRDTNRKGEVIRESLDKLPKPNGSLLGVKPVIKGDSDLPPVEKADLVVVAGRGVAGP
EGVKLLIELAKALGGTIGGSKKVTDAGWLPADRQIGQTGKTIRPTVYIGVGVSGAIQHIFGMKESKIIVAINSDPNAPIF
EYADYGIVGDYRQVVQALLETLSSMRKTN

Specific function: The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase) [H]

COG id: COG2025

COG function: function code C; Electron transfer flavoprotein, alpha subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ETF alpha-subunit/fixB family [H]

Homologues:

Organism=Homo sapiens, GI4503607, Length=336, Percent_Identity=33.0357142857143, Blast_Score=152, Evalue=6e-37,
Organism=Homo sapiens, GI189181759, Length=280, Percent_Identity=35.3571428571429, Blast_Score=142, Evalue=4e-34,
Organism=Escherichia coli, GI1787990, Length=254, Percent_Identity=35.4330708661417, Blast_Score=128, Evalue=5e-31,
Organism=Escherichia coli, GI1786226, Length=309, Percent_Identity=29.126213592233, Blast_Score=117, Evalue=8e-28,
Organism=Escherichia coli, GI87082157, Length=258, Percent_Identity=28.6821705426357, Blast_Score=82, Evalue=5e-17,
Organism=Caenorhabditis elegans, GI17506929, Length=332, Percent_Identity=31.9277108433735, Blast_Score=144, Evalue=9e-35,
Organism=Saccharomyces cerevisiae, GI6325261, Length=269, Percent_Identity=33.8289962825279, Blast_Score=134, Evalue=2e-32,
Organism=Drosophila melanogaster, GI17136898, Length=321, Percent_Identity=32.7102803738318, Blast_Score=152, Evalue=3e-37,
Organism=Drosophila melanogaster, GI24652801, Length=321, Percent_Identity=32.7102803738318, Blast_Score=152, Evalue=3e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001308
- InterPro:   IPR014730
- InterPro:   IPR014731
- InterPro:   IPR018206
- InterPro:   IPR014729 [H]

Pfam domain/function: PF01012 ETF; PF00766 ETF_alpha [H]

EC number: NA

Molecular weight: Translated: 38050; Mature: 37919

Theoretical pI: Translated: 9.41; Mature: 9.41

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSARICPEWPQVNKSEYKGIWVYIEHQNGVIKDGSLQLIGKARELAAKINVDVSAVMIG
CCCCCCCCCCCCCCCCCCCEEEEEEECCCCEEECCCEEEEHHHHHHHHHCCCCEEEEEEC
HNLGDLVKEPIYYGADRVIYIDDEALSVYIPHLYASVIVNLVNKYKPEVVLFAATKRGRE
CCHHHHHHHHHHCCCCEEEEEECCCEEEEHHHHHHHHHHHHHHHCCCCEEEEEECCCCCC
LAPYVANTLRAGITADCTDLDIDVKTRDLDQVRPTYGGNILAHIRTPNRRPQLASVRPNV
HHHHHHHHHHCCCCCCCCCCEEEEECCCHHHCCCCCCCCEEEEEECCCCCCCCCCCCCCC
FPTPPRDTNRKGEVIRESLDKLPKPNGSLLGVKPVIKGDSDLPPVEKADLVVVAGRGVAG
CCCCCCCCCCHHHHHHHHHHHCCCCCCCEEEEEEEECCCCCCCCCCCCCEEEEECCCCCC
PEGVKLLIELAKALGGTIGGSKKVTDAGWLPADRQIGQTGKTIRPTVYIGVGVSGAIQHI
HHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCEECCEEEEECCCHHHHHHH
FGMKESKIIVAINSDPNAPIFEYADYGIVGDYRQVVQALLETLSSMRKTN
HCCCCCEEEEEECCCCCCCEEECCCCCEEHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SSARICPEWPQVNKSEYKGIWVYIEHQNGVIKDGSLQLIGKARELAAKINVDVSAVMIG
CCCCCCCCCCCCCCCCCCEEEEEEECCCCEEECCCEEEEHHHHHHHHHCCCCEEEEEEC
HNLGDLVKEPIYYGADRVIYIDDEALSVYIPHLYASVIVNLVNKYKPEVVLFAATKRGRE
CCHHHHHHHHHHCCCCEEEEEECCCEEEEHHHHHHHHHHHHHHHCCCCEEEEEECCCCCC
LAPYVANTLRAGITADCTDLDIDVKTRDLDQVRPTYGGNILAHIRTPNRRPQLASVRPNV
HHHHHHHHHHCCCCCCCCCCEEEEECCCHHHCCCCCCCCEEEEEECCCCCCCCCCCCCCC
FPTPPRDTNRKGEVIRESLDKLPKPNGSLLGVKPVIKGDSDLPPVEKADLVVVAGRGVAG
CCCCCCCCCCHHHHHHHHHHHCCCCCCCEEEEEEEECCCCCCCCCCCCCEEEEECCCCCC
PEGVKLLIELAKALGGTIGGSKKVTDAGWLPADRQIGQTGKTIRPTVYIGVGVSGAIQHI
HHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCEECCEEEEECCCHHHHHHH
FGMKESKIIVAINSDPNAPIFEYADYGIVGDYRQVVQALLETLSSMRKTN
HCCCCCEEEEEECCCCCCCEEECCCCCEEHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8655474; 11466286 [H]