Click here to switch to the map view.

The map label for this gene is psmB1

Identifier: 159041041

GI number: 159041041

Start: 497707

End: 498327

Strand: Reverse

Name: psmB1

Synonym: Cmaq_0458

Alternate gene names: 159041041

Gene position: 498327-497707 (Counterclockwise)

Preceding gene: 159041042

Following gene: 159041040

Centisome position: 23.99

GC content: 48.15

Gene sequence:

>621_bases
GTGAGTAGGATTCATAATGATCCAAAGGTCCTATTAACTGGAACAACAACAGTGGGTGTGGTTACTAAGGAGGGTGTTGT
ATTAGCCACTGACAGGAGGGTTACCGCAGGCTACTACATAGCTCATAGGAAGGGTAGGAAGATATGGAAGATTGATAACC
ACGCGGCAGCAACAATGAGTGGGGCAGTGGCTGATGTACAAATGATACTAAATGAATTAACCCACTTAGCAATGAACTAT
AGGATAACGCACCAAGCCCCAGTACCAATTAAGACGCTAGCTAACTATGCCTCAGTAGTCATGTTCTACAGCAGGCCGAT
GATATACATAGCCCACATGATAATAGGTGGAGTGGATAATGAGGAGGGGCCGGTCCTATATGCGGTTGACTGGTACGGTA
GCTTCACAAGGGAGGAACGCTTCATGTCAACGGGCAGTGGTTCACCAACGGCCTTCGGTGTGCTTGAGGATGGTTATAGG
GATGACATGAGCCTTGATGATGCTGTTAAGCTAGCCACCAGGGCGGTTAGAGCGGCGATGCTTCATGACCCAGGAAGTGG
AGAGGGTGTTGACGTCATAACCATAACTAAGGAGGCTGGGTATAGGGAAGTACAGGCTTAA

Upstream 100 bases:

>100_bases
CAGCAAACCCAGCAACCACAGGCTACTCAGGAGGAGGCTCAACAGGCACAGGCGGCTGCACAACAGCCGCAGCAGATTCA
GCAGACTCAGGGTGGTTCCA

Downstream 100 bases:

>100_bases
ACAAGTTTACTCATTATCCTCCTCGTATTAAAACTAGTCAAGTATCCTCGCTTAGAGAGAAGCTTAATGACCTTATTCAC
AGTATTCTAAATTACCCTCA

Product: proteasome endopeptidase complex protein

Products: NA

Alternate protein names: 20S proteasome beta subunit 1; Proteasome core protein PsmB 1

Number of amino acids: Translated: 206; Mature: 205

Protein sequence:

>206_residues
MSRIHNDPKVLLTGTTTVGVVTKEGVVLATDRRVTAGYYIAHRKGRKIWKIDNHAAATMSGAVADVQMILNELTHLAMNY
RITHQAPVPIKTLANYASVVMFYSRPMIYIAHMIIGGVDNEEGPVLYAVDWYGSFTREERFMSTGSGSPTAFGVLEDGYR
DDMSLDDAVKLATRAVRAAMLHDPGSGEGVDVITITKEAGYREVQA

Sequences:

>Translated_206_residues
MSRIHNDPKVLLTGTTTVGVVTKEGVVLATDRRVTAGYYIAHRKGRKIWKIDNHAAATMSGAVADVQMILNELTHLAMNY
RITHQAPVPIKTLANYASVVMFYSRPMIYIAHMIIGGVDNEEGPVLYAVDWYGSFTREERFMSTGSGSPTAFGVLEDGYR
DDMSLDDAVKLATRAVRAAMLHDPGSGEGVDVITITKEAGYREVQA
>Mature_205_residues
SRIHNDPKVLLTGTTTVGVVTKEGVVLATDRRVTAGYYIAHRKGRKIWKIDNHAAATMSGAVADVQMILNELTHLAMNYR
ITHQAPVPIKTLANYASVVMFYSRPMIYIAHMIIGGVDNEEGPVLYAVDWYGSFTREERFMSTGSGSPTAFGVLEDGYRD
DMSLDDAVKLATRAVRAAMLHDPGSGEGVDVITITKEAGYREVQA

Specific function: Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation

COG id: COG0638

COG function: function code O; 20S proteasome, alpha and beta subunits

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase T1B family

Homologues:

Organism=Homo sapiens, GI4506203, Length=196, Percent_Identity=35.2040816326531, Blast_Score=96, Evalue=3e-20,
Organism=Homo sapiens, GI73747875, Length=194, Percent_Identity=33.5051546391753, Blast_Score=88, Evalue=4e-18,
Organism=Homo sapiens, GI4758970, Length=194, Percent_Identity=33.5051546391753, Blast_Score=88, Evalue=4e-18,
Organism=Homo sapiens, GI4506201, Length=208, Percent_Identity=32.2115384615385, Blast_Score=86, Evalue=2e-17,
Organism=Homo sapiens, GI4506191, Length=191, Percent_Identity=34.0314136125654, Blast_Score=86, Evalue=3e-17,
Organism=Homo sapiens, GI23110925, Length=192, Percent_Identity=30.7291666666667, Blast_Score=80, Evalue=1e-15,
Organism=Homo sapiens, GI153791216, Length=207, Percent_Identity=31.8840579710145, Blast_Score=79, Evalue=4e-15,
Organism=Homo sapiens, GI4506205, Length=184, Percent_Identity=28.2608695652174, Blast_Score=72, Evalue=5e-13,
Organism=Homo sapiens, GI156713442, Length=196, Percent_Identity=27.0408163265306, Blast_Score=71, Evalue=8e-13,
Organism=Homo sapiens, GI4506185, Length=196, Percent_Identity=27.0408163265306, Blast_Score=71, Evalue=8e-13,
Organism=Homo sapiens, GI23110942, Length=178, Percent_Identity=27.5280898876405, Blast_Score=70, Evalue=1e-12,
Organism=Homo sapiens, GI4506193, Length=202, Percent_Identity=24.2574257425743, Blast_Score=65, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI17508495, Length=197, Percent_Identity=34.5177664974619, Blast_Score=85, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI17508499, Length=190, Percent_Identity=29.4736842105263, Blast_Score=84, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI17541700, Length=188, Percent_Identity=30.3191489361702, Blast_Score=80, Evalue=8e-16,
Organism=Caenorhabditis elegans, GI17535357, Length=186, Percent_Identity=22.5806451612903, Blast_Score=72, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17508493, Length=192, Percent_Identity=28.125, Blast_Score=69, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6324731, Length=200, Percent_Identity=32.5, Blast_Score=90, Evalue=2e-19,
Organism=Saccharomyces cerevisiae, GI6325360, Length=193, Percent_Identity=28.4974093264249, Blast_Score=85, Evalue=6e-18,
Organism=Saccharomyces cerevisiae, GI6321574, Length=195, Percent_Identity=27.1794871794872, Blast_Score=74, Evalue=2e-14,
Organism=Saccharomyces cerevisiae, GI6322459, Length=184, Percent_Identity=27.1739130434783, Blast_Score=67, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6324938, Length=178, Percent_Identity=27.5280898876405, Blast_Score=64, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24639979, Length=197, Percent_Identity=31.4720812182741, Blast_Score=97, Evalue=1e-20,
Organism=Drosophila melanogaster, GI20130281, Length=191, Percent_Identity=34.0314136125654, Blast_Score=91, Evalue=6e-19,
Organism=Drosophila melanogaster, GI24653999, Length=194, Percent_Identity=30.4123711340206, Blast_Score=88, Evalue=3e-18,
Organism=Drosophila melanogaster, GI24584895, Length=191, Percent_Identity=31.413612565445, Blast_Score=84, Evalue=7e-17,
Organism=Drosophila melanogaster, GI21355573, Length=188, Percent_Identity=32.9787234042553, Blast_Score=82, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24652553, Length=188, Percent_Identity=32.9787234042553, Blast_Score=82, Evalue=2e-16,
Organism=Drosophila melanogaster, GI28573221, Length=191, Percent_Identity=31.9371727748691, Blast_Score=74, Evalue=5e-14,
Organism=Drosophila melanogaster, GI24664391, Length=180, Percent_Identity=27.2222222222222, Blast_Score=74, Evalue=8e-14,
Organism=Drosophila melanogaster, GI24654391, Length=201, Percent_Identity=26.3681592039801, Blast_Score=74, Evalue=9e-14,
Organism=Drosophila melanogaster, GI24654389, Length=201, Percent_Identity=26.3681592039801, Blast_Score=74, Evalue=9e-14,
Organism=Drosophila melanogaster, GI17737927, Length=170, Percent_Identity=27.6470588235294, Blast_Score=64, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PSB1_CALMQ (A8MBW0)

Other databases:

- EMBL:   CP000852
- RefSeq:   YP_001540293.1
- ProteinModelPortal:   A8MBW0
- SMR:   A8MBW0
- MEROPS:   T01.002
- GeneID:   5709933
- GenomeReviews:   CP000852_GR
- KEGG:   cma:Cmaq_0458
- HOGENOM:   HBG499923
- OMA:   MAYGVLE
- ProtClustDB:   CLSK899561
- GO:   GO:0005737
- HAMAP:   MF_02113_A
- InterPro:   IPR000243
- InterPro:   IPR001353
- PRINTS:   PR00141

Pfam domain/function: PF00227 Proteasome

EC number: =3.4.25.1

Molecular weight: Translated: 22566; Mature: 22435

Theoretical pI: Translated: 6.90; Mature: 6.90

Prosite motif: PS00854 PROTEASOME_B_1; PS51476 PROTEASOME_B_2

Important sites: ACT_SITE 15-15

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.9 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.4 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRIHNDPKVLLTGTTTVGVVTKEGVVLATDRRVTAGYYIAHRKGRKIWKIDNHAAATMS
CCCCCCCCEEEEECCCEEEEEEECCEEEEECCEEEEEEEEEECCCCEEEEECCCCHHHHH
GAVADVQMILNELTHLAMNYRITHQAPVPIKTLANYASVVMFYSRPMIYIAHMIIGGVDN
HHHHHHHHHHHHHHHHHHCEEEECCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCC
EEGPVLYAVDWYGSFTREERFMSTGSGSPTAFGVLEDGYRDDMSLDDAVKLATRAVRAAM
CCCCEEEEEECCCCCHHHHHHHHCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHH
LHDPGSGEGVDVITITKEAGYREVQA
HCCCCCCCCEEEEEEECCCCCEECCC
>Mature Secondary Structure 
SRIHNDPKVLLTGTTTVGVVTKEGVVLATDRRVTAGYYIAHRKGRKIWKIDNHAAATMS
CCCCCCCEEEEECCCEEEEEEECCEEEEECCEEEEEEEEEECCCCEEEEECCCCHHHHH
GAVADVQMILNELTHLAMNYRITHQAPVPIKTLANYASVVMFYSRPMIYIAHMIIGGVDN
HHHHHHHHHHHHHHHHHHCEEEECCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCC
EEGPVLYAVDWYGSFTREERFMSTGSGSPTAFGVLEDGYRDDMSLDDAVKLATRAVRAAM
CCCCEEEEEECCCCCHHHHHHHHCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHH
LHDPGSGEGVDVITITKEAGYREVQA
HCCCCCCCCEEEEEEECCCCCEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA