Click here to switch to the map view.

The map label for this gene is uxaA [H]

Identifier: 159040794

GI number: 159040794

Start: 244874

End: 246046

Strand: Reverse

Name: uxaA [H]

Synonym: Cmaq_0207

Alternate gene names: 159040794

Gene position: 246046-244874 (Counterclockwise)

Preceding gene: 159040795

Following gene: 159040792

Centisome position: 11.84

GC content: 47.23

Gene sequence:

>1173_bases
ATGAGCAGTAGGCCAACGGTAATGGGTTACATTAGGCCAGATGGTAGAGTTGGTATTAGGAACCACGTCCTAGTATTATC
AACAGTAATATGCTCAAGCATAGTAACCCGTAGAATTGCTGATCAGGTAAAGGGTGCAGTGGCTATTGAGAATCCCTTCG
GCTGCGGGCAACTTGAACCAGACCTACAAGTCACTAAGAGGACTCTTGCTGGAATGGCTAAGAACCCTAATGTGGGTGCA
GTATTAGTTGTTGGCCTTGGATGTGAGCAGATTCAGGCTGATGAACTTGCTGATGAAATAGCCAAGACAGGTAAGCCTGT
TGAGAGGGTGGTTATACAGGAGGAGAACGGTGGTACACCAGCGGCTATTGAGAAGGGTGTTAAGTTGCTCAGTAGGATGG
CTGAGGAGACTCTTACCCAGAGGCCAACTGAAGTGGATGCATCATCACTAGTAATGGGTGTTGAATGCGGTGGTTCAGAT
GCCACATCAGGCTTAGCCTCAAATCCAGTTGTGGGTTATGTGTCAGATAGGTTAATTGACTTAGGGGGAACAGTTATTTT
ATCGGAGACCCCTGAGATGATAGGGGCTGAGGATATTTTAGCTAAGAGGGCTGCATCAAAGGAGGTGGCTGATAAGGTTT
ACAATGCAATTAGGAGGTGGGTTGAATTAGCTGCATCACATAACGTTGACTTAGTTGGTACTCAACCAGCCCCTGGAAAC
ATAGCTGGAGGCATATCCACAATTGAGGAGAAGTCGCTTGGTGCCATAATTAAGGGTGGGTCAAGGCAGATTCAAGGCGT
ATTAAATTATGCGGAGGAGGTTAAGGGTAAGGGCCTCTGGATAATGGATACTCCAGGTTACGACATAATGTCAGTGGTGG
GTATGGTGGCTGGGGGAGCAACACTAGTAGTGTTCACCACAGGTAGGGGGACTCCAACCGGTAATCCAATAGCCCCGGTG
ATTAAGGTGACCGCTAACCCATACACATACGGTAAGATGAAGGAGAACATTGACTTCGATGCAAGCACCGTGATTAATGG
CACTGAGACTGTTGAGCAGGCTGGGGAGAGGTTACTTAACCTTGTCCTTGAGGTCGCCAGAGGTAGGCATACTAAGGCTG
AGTTACTTGGGCATACGGAATTCATGATACATAAGATAATACCATCCTTCTAA

Upstream 100 bases:

>100_bases
TAGGTAGGGCTAAGAGGGATATTAAGGCCGGGGAGCATGTTCATGTTCATAACCTTGAAAGCTTAACCTCAGTGCATAGT
GTATGTAGGGGTGAGGGTGC

Downstream 100 bases:

>100_bases
ATACGCATTGATCATTTATTTTAAATTTAAATTAATTTTCTAAATCTAAATTAGTTATAACACTGATTAAGCCTGAATCC
TCATTACCCTACTTAATTCA

Product: Altronate dehydratase

Products: NA

Alternate protein names: Altronic acid hydratase [H]

Number of amino acids: Translated: 390; Mature: 389

Protein sequence:

>390_residues
MSSRPTVMGYIRPDGRVGIRNHVLVLSTVICSSIVTRRIADQVKGAVAIENPFGCGQLEPDLQVTKRTLAGMAKNPNVGA
VLVVGLGCEQIQADELADEIAKTGKPVERVVIQEENGGTPAAIEKGVKLLSRMAEETLTQRPTEVDASSLVMGVECGGSD
ATSGLASNPVVGYVSDRLIDLGGTVILSETPEMIGAEDILAKRAASKEVADKVYNAIRRWVELAASHNVDLVGTQPAPGN
IAGGISTIEEKSLGAIIKGGSRQIQGVLNYAEEVKGKGLWIMDTPGYDIMSVVGMVAGGATLVVFTTGRGTPTGNPIAPV
IKVTANPYTYGKMKENIDFDASTVINGTETVEQAGERLLNLVLEVARGRHTKAELLGHTEFMIHKIIPSF

Sequences:

>Translated_390_residues
MSSRPTVMGYIRPDGRVGIRNHVLVLSTVICSSIVTRRIADQVKGAVAIENPFGCGQLEPDLQVTKRTLAGMAKNPNVGA
VLVVGLGCEQIQADELADEIAKTGKPVERVVIQEENGGTPAAIEKGVKLLSRMAEETLTQRPTEVDASSLVMGVECGGSD
ATSGLASNPVVGYVSDRLIDLGGTVILSETPEMIGAEDILAKRAASKEVADKVYNAIRRWVELAASHNVDLVGTQPAPGN
IAGGISTIEEKSLGAIIKGGSRQIQGVLNYAEEVKGKGLWIMDTPGYDIMSVVGMVAGGATLVVFTTGRGTPTGNPIAPV
IKVTANPYTYGKMKENIDFDASTVINGTETVEQAGERLLNLVLEVARGRHTKAELLGHTEFMIHKIIPSF
>Mature_389_residues
SSRPTVMGYIRPDGRVGIRNHVLVLSTVICSSIVTRRIADQVKGAVAIENPFGCGQLEPDLQVTKRTLAGMAKNPNVGAV
LVVGLGCEQIQADELADEIAKTGKPVERVVIQEENGGTPAAIEKGVKLLSRMAEETLTQRPTEVDASSLVMGVECGGSDA
TSGLASNPVVGYVSDRLIDLGGTVILSETPEMIGAEDILAKRAASKEVADKVYNAIRRWVELAASHNVDLVGTQPAPGNI
AGGISTIEEKSLGAIIKGGSRQIQGVLNYAEEVKGKGLWIMDTPGYDIMSVVGMVAGGATLVVFTTGRGTPTGNPIAPVI
KVTANPYTYGKMKENIDFDASTVINGTETVEQAGERLLNLVLEVARGRHTKAELLGHTEFMIHKIIPSF

Specific function: Hexuronate conversion to KDG. [C]

COG id: COG2721

COG function: function code G; Altronate dehydratase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the uxaA family [H]

Homologues:

Organism=Escherichia coli, GI1789475, Length=387, Percent_Identity=34.625322997416, Blast_Score=224, Evalue=7e-60,
Organism=Escherichia coli, GI1789516, Length=386, Percent_Identity=34.7150259067358, Blast_Score=194, Evalue=6e-51,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007392
- InterPro:   IPR013974 [H]

Pfam domain/function: PF04295 GD_AH_C; PF08666 SAF [H]

EC number: =4.2.1.7 [H]

Molecular weight: Translated: 41166; Mature: 41035

Theoretical pI: Translated: 5.31; Mature: 5.31

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSRPTVMGYIRPDGRVGIRNHVLVLSTVICSSIVTRRIADQVKGAVAIENPFGCGQLEP
CCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCCCCCC
DLQVTKRTLAGMAKNPNVGAVLVVGLGCEQIQADELADEIAKTGKPVERVVIQEENGGTP
HHHHHHHHHHCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHCCCCEEEEEEEECCCCCH
AAIEKGVKLLSRMAEETLTQRPTEVDASSLVMGVECGGSDATSGLASNPVVGYVSDRLID
HHHHHHHHHHHHHHHHHHHCCCCCCCHHHEEEEEECCCCCCCCCCCCCCEEEHHHHHHHH
LGGTVILSETPEMIGAEDILAKRAASKEVADKVYNAIRRWVELAASHNVDLVGTQPAPGN
CCCEEEEECCCHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCC
IAGGISTIEEKSLGAIIKGGSRQIQGVLNYAEEVKGKGLWIMDTPGYDIMSVVGMVAGGA
CCCCHHHHHHHHCCCEECCCHHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHCCCC
TLVVFTTGRGTPTGNPIAPVIKVTANPYTYGKMKENIDFDASTVINGTETVEQAGERLLN
EEEEEECCCCCCCCCCCCCEEEEECCCCCCCCHHCCCCCCHHHEECCHHHHHHHHHHHHH
LVLEVARGRHTKAELLGHTEFMIHKIIPSF
HHHHHHCCCCCHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
SSRPTVMGYIRPDGRVGIRNHVLVLSTVICSSIVTRRIADQVKGAVAIENPFGCGQLEP
CCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCCCCCC
DLQVTKRTLAGMAKNPNVGAVLVVGLGCEQIQADELADEIAKTGKPVERVVIQEENGGTP
HHHHHHHHHHCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHCCCCEEEEEEEECCCCCH
AAIEKGVKLLSRMAEETLTQRPTEVDASSLVMGVECGGSDATSGLASNPVVGYVSDRLID
HHHHHHHHHHHHHHHHHHHCCCCCCCHHHEEEEEECCCCCCCCCCCCCCEEEHHHHHHHH
LGGTVILSETPEMIGAEDILAKRAASKEVADKVYNAIRRWVELAASHNVDLVGTQPAPGN
CCCEEEEECCCHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCC
IAGGISTIEEKSLGAIIKGGSRQIQGVLNYAEEVKGKGLWIMDTPGYDIMSVVGMVAGGA
CCCCHHHHHHHHCCCEECCCHHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHCCCC
TLVVFTTGRGTPTGNPIAPVIKVTANPYTYGKMKENIDFDASTVINGTETVEQAGERLLN
EEEEEECCCCCCCCCCCCCEEEEECCCCCCCCHHCCCCCCHHHEECCHHHHHHHHHHHHH
LVLEVARGRHTKAELLGHTEFMIHKIIPSF
HHHHHHCCCCCHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9278503; 3038546 [H]