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The map label for this gene is asd [H]

Identifier: 159040600

GI number: 159040600

Start: 21262

End: 22293

Strand: Reverse

Name: asd [H]

Synonym: Cmaq_0008

Alternate gene names: 159040600

Gene position: 22293-21262 (Counterclockwise)

Preceding gene: 159040601

Following gene: 159040599

Centisome position: 1.07

GC content: 47.58

Gene sequence:

>1032_bases
GTGGGTGGTGTCATGGATAAGGTGAGGGTTTCAATACTTGGGGCAACGGGCCTAGTGGGGCAGTGGATGGTTAAGCTACT
TGAGAATCACCCATACATTGAAGTGACCGCCCTATCAGCCTCACCGGGTAAGGTTGGGCAGAGGTATGGTGATGTTGTTA
AGTGGTTCATAGAGGGCGACGTCCCTGAGTACGCGAGGGGAATTAAATTAACCTCAACTGACCCTGTGGATCAAAGGAAC
GTTGATGTTGTTTTATCAGCGTTACCTAATGATGTTGCTGAACCCGTTGAGGCTAAGCTACTTGAGGCTGGTTTAAACGT
AATATCTAATGCCTCCCCAAGGAGAATGGACCCTAATGTACCCTTAATAAACCCTGAGGTGAATTGGCAGCATCTTGAGG
TTTTAAGGGAATCCAAGGGATCTTGGCTCGTGAAGAACCCTAACTGCACATCAGCCATAATTACCCTGGCGATAAAGCCA
TTGGCGGAGCATATTAAGGAATTATACGTTACTACGCTTCAAGCTGTTTCAGGGGCTGGTTACATGGGTTTATCGTACCT
AGCCATTGAGGGTAATGTAATACCATTCATTAAGGGTGAGGAGGATAAGATAGCTGCTGAGTCAAATAAGATGCTGGGTA
TTATGGGTAAGGGTAAGTATGAACCATGGGGTAGACCCGTTAGGGTTACCTCAATAAGGGTCCCGGTTAAGTATGGTCAC
ATGGCCTCAATATTCATGGTTATGGATAAGGAGTACAGTGTTGATGATGTTAAACGTGAGTTAACAGGCTTCAAGTCACT
ACCCCAGGAGGCTAACCTACCCACTGCACCACCCAGGCCGATAATAGTATCCGATAGGCCTGACGCCCCCCAGCCGGCTA
GGGATCTGGATCACATGGCCGTCACTGTGGGTAGGTTAATGGCCTCAGGTAACGTTGTTAGGATGGTTGCCTTAGGCGAT
AACCTGGTTAGGGGTGCTGCGGGTATAACGATATTGACCTTAGAGACTATGAGGGCTATGAGGCTTATTTAA

Upstream 100 bases:

>100_bases
ACGACCCAGTGGACGTGGTAAATGATACTGAGGGTAACGCAGTCTCATCAATAGTTAAGGATCAGGATGAAGCGGTTAAG
TTGGCTAAGGACCTGCACAA

Downstream 100 bases:

>100_bases
GCACTCAATACTGTTTATTCCAGTGTCCTAGGTTTCTATGGTTACTTAGGGAAAGGTTTATATAGAAGCGGCTTCTGGGG
ATGCATATGTCAACAGCTCA

Product: aspartate-semialdehyde dehydrogenase

Products: NA

Alternate protein names: ASA dehydrogenase; ASADH [H]

Number of amino acids: Translated: 343; Mature: 342

Protein sequence:

>343_residues
MGGVMDKVRVSILGATGLVGQWMVKLLENHPYIEVTALSASPGKVGQRYGDVVKWFIEGDVPEYARGIKLTSTDPVDQRN
VDVVLSALPNDVAEPVEAKLLEAGLNVISNASPRRMDPNVPLINPEVNWQHLEVLRESKGSWLVKNPNCTSAIITLAIKP
LAEHIKELYVTTLQAVSGAGYMGLSYLAIEGNVIPFIKGEEDKIAAESNKMLGIMGKGKYEPWGRPVRVTSIRVPVKYGH
MASIFMVMDKEYSVDDVKRELTGFKSLPQEANLPTAPPRPIIVSDRPDAPQPARDLDHMAVTVGRLMASGNVVRMVALGD
NLVRGAAGITILTLETMRAMRLI

Sequences:

>Translated_343_residues
MGGVMDKVRVSILGATGLVGQWMVKLLENHPYIEVTALSASPGKVGQRYGDVVKWFIEGDVPEYARGIKLTSTDPVDQRN
VDVVLSALPNDVAEPVEAKLLEAGLNVISNASPRRMDPNVPLINPEVNWQHLEVLRESKGSWLVKNPNCTSAIITLAIKP
LAEHIKELYVTTLQAVSGAGYMGLSYLAIEGNVIPFIKGEEDKIAAESNKMLGIMGKGKYEPWGRPVRVTSIRVPVKYGH
MASIFMVMDKEYSVDDVKRELTGFKSLPQEANLPTAPPRPIIVSDRPDAPQPARDLDHMAVTVGRLMASGNVVRMVALGD
NLVRGAAGITILTLETMRAMRLI
>Mature_342_residues
GGVMDKVRVSILGATGLVGQWMVKLLENHPYIEVTALSASPGKVGQRYGDVVKWFIEGDVPEYARGIKLTSTDPVDQRNV
DVVLSALPNDVAEPVEAKLLEAGLNVISNASPRRMDPNVPLINPEVNWQHLEVLRESKGSWLVKNPNCTSAIITLAIKPL
AEHIKELYVTTLQAVSGAGYMGLSYLAIEGNVIPFIKGEEDKIAAESNKMLGIMGKGKYEPWGRPVRVTSIRVPVKYGHM
ASIFMVMDKEYSVDDVKRELTGFKSLPQEANLPTAPPRPIIVSDRPDAPQPARDLDHMAVTVGRLMASGNVVRMVALGDN
LVRGAAGITILTLETMRAMRLI

Specific function: This enzyme catalyzes the second step in the common metabolic pathway to synthesize Thr and Met from Asp [H]

COG id: COG0136

COG function: function code E; Aspartate-semialdehyde dehydrogenase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aspartate-semialdehyde dehydrogenase family [H]

Homologues:

Organism=Saccharomyces cerevisiae, GI6320362, Length=357, Percent_Identity=34.1736694677871, Blast_Score=172, Evalue=8e-44,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000319
- InterPro:   IPR005676
- InterPro:   IPR012080
- InterPro:   IPR016040
- InterPro:   IPR000534
- InterPro:   IPR012280 [H]

Pfam domain/function: PF01118 Semialdhyde_dh; PF02774 Semialdhyde_dhC [H]

EC number: =1.2.1.11 [H]

Molecular weight: Translated: 37410; Mature: 37279

Theoretical pI: Translated: 7.70; Mature: 7.70

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGGVMDKVRVSILGATGLVGQWMVKLLENHPYIEVTALSASPGKVGQRYGDVVKWFIEGD
CCCCHHHHEEEEECCCCHHHHHHHHHHHCCCEEEEEEECCCCCHHHHHHHHHEEEEECCC
VPEYARGIKLTSTDPVDQRNVDVVLSALPNDVAEPVEAKLLEAGLNVISNASPRRMDPNV
CHHHHCCEEECCCCCCCCCCHHHHEECCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
PLINPEVNWQHLEVLRESKGSWLVKNPNCTSAIITLAIKPLAEHIKELYVTTLQAVSGAG
CEECCCCCHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
YMGLSYLAIEGNVIPFIKGEEDKIAAESNKMLGIMGKGKYEPWGRPVRVTSIRVPVKYGH
CCCEEEEEEECCEEEEEECCCCCEECCCCCEEEEEECCCCCCCCCCEEEEEEEEEEECCC
MASIFMVMDKEYSVDDVKRELTGFKSLPQEANLPTAPPRPIIVSDRPDAPQPARDLDHMA
CEEEEEEECCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCEEECCCCCCCCCHHHHHHHH
VTVGRLMASGNVVRMVALGDNLVRGAAGITILTLETMRAMRLI
HHHHHHHHCCCEEEEEEECCCHHHCCCCEEEEEHHHHHHHHCC
>Mature Secondary Structure 
GGVMDKVRVSILGATGLVGQWMVKLLENHPYIEVTALSASPGKVGQRYGDVVKWFIEGD
CCCHHHHEEEEECCCCHHHHHHHHHHHCCCEEEEEEECCCCCHHHHHHHHHEEEEECCC
VPEYARGIKLTSTDPVDQRNVDVVLSALPNDVAEPVEAKLLEAGLNVISNASPRRMDPNV
CHHHHCCEEECCCCCCCCCCHHHHEECCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
PLINPEVNWQHLEVLRESKGSWLVKNPNCTSAIITLAIKPLAEHIKELYVTTLQAVSGAG
CEECCCCCHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
YMGLSYLAIEGNVIPFIKGEEDKIAAESNKMLGIMGKGKYEPWGRPVRVTSIRVPVKYGH
CCCEEEEEEECCEEEEEECCCCCEECCCCCEEEEEECCCCCCCCCCEEEEEEEEEEECCC
MASIFMVMDKEYSVDDVKRELTGFKSLPQEANLPTAPPRPIIVSDRPDAPQPARDLDHMA
CEEEEEEECCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCEEECCCCCCCCCHHHHHHHH
VTVGRLMASGNVVRMVALGDNLVRGAAGITILTLETMRAMRLI
HHHHHHHHCCCEEEEEEECCCHHHCCCCEEEEEHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9371463 [H]