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The map label for this gene is cutA-8 [H]

Identifier: 15899937

GI number: 15899937

Start: 2982208

End: 2984340

Strand: Direct

Name: cutA-8 [H]

Synonym: SSO3239

Alternate gene names: 15899937

Gene position: 2982208-2984340 (Clockwise)

Preceding gene: 15899936

Following gene: 15899938

Centisome position: 99.66

GC content: 37.65

Gene sequence:

>2133_bases
GTGTACGTTGGCAAACCTATTAAGCGAATCGAAGATCCTAAATTCTTAACTGGAGGCTCAACATACGTTGATGATATAGA
ACTTCCAGGTACATTATTTGTGGCATTTCTCAGATCGGTTAAACCACACGCTAAAATAAAGATAAAGAAGAATGGTAATA
ACGTATTTACTGGTTATGACATCAATCCAGGTAAGGATTTTCCAATACCCATAGAGGAGACAACTTACGTTGGTCAACCA
TTAGCTATTGTAGTAGGAAGGGATAGATATGAAGCTTATGACTTGTTAGAAAGTATTGAAGTAGAATATGAGGAGTTACC
TTACGTTATTGATCCTCAAGATGCTTTAAAAAACGATGTAAAAGTTTACAGTAAGAAGGAGTCTAATATTTACGAATATA
AGAAATGGGAAGGAGGAAATATTGAACAGAGTCTTAAAGAGGCTGATGTGGTAATTAACGGAGAGTTATATAATCAAAGA
GTAATAGCAAACCCCTTAGAAACTAGGGGAATATTAGCTTACTTCGATGGTAATAGGTTAAATGTATGGTCATCTACTCA
ATCAGCTCATTATCTTAGAAGAAATCTCATGAACTTTCTTGGAATTGATAACATAAGGGTAATTCAGCCAGATGTAGGAG
GAGCGTTTGGGAGTAAAATTATAGCTCATCCGGAAGAATATGCTATAGCTAAGCTAGCCTTAAAAATGAAGAGACCTTTA
AAGTGGATACCAACCAGGTCTGAAGAGATGCAGAGTGCAGGTCATGGAAGAGATAAGAGATTAAAGTTTAAGGTTGCAGT
AAAGAGAGATGGTACAATACTAGGTATAGATGGTACTTTAATTGCCGATTTGGGAGCGCCTTATCCAGACGCAAACGATG
ATGAGATAGGCAATGTTCACAGTACAGTTAGAATGCTATTGGGACCTTATAGGATTCAAAACGTGAGAATAGAGGAATAC
GCTGTAAACACCAACAAGGCACCTACTCAATCATATAGGGGAGCGGGTAGACCAGAGGCAACATATTTCATAGAGAGAAT
TATTAATATAATCTCTTTGGAGCTAGGAAAGGATGAATTTGATATAAGAGAGAAGAATTTGATTAGAGAACTACCATACA
AGAATGCCTTGGGTATAACCTATGATACTGGAGATTATATTGGTCTATTAAATAAAGCAAGAGAATACTATGAGACGTTG
AAAAAAGAAGCTAGCACGGATGAATGTATAGGTTCAAGTATGTACGTCGAAATAACAGCATTTGGCCCTTGGGAGACCGC
AAGAGTTCTAGCTAAAAGTGACGGAAAAATCATGATAATAACTGGCAGTGGACCTCATGGGCAAGGTGATGGTACTGCTT
TTGCCCAAATAGTAGCCGATGTTCTAGAGATTCCAATAGAGAATATTGAAGTTAGATGGGGAGACACTGATATAATTTCA
GATGGGATTGGAACTTGGGGAAGTAGAACAGTAACAATTGGTGGGTCAGCGATGTATAAGGCTGCAGAAGAGTTAAGGAG
AAGATTGATTGAAGTAAGTGCAAAAATGTTAAACGCTGACGTGGAAGAGGTAGAGTATAAGAATGGGATATTTTCGCATA
AGAAGAGCAGTAAGAGTTTTACTATAAAGGAAGTAATACAAAACGCTTATTCAATGGGATACTCCTTAGATGTAACCTAT
GTCTATAACGTAACTAAACCAGGTTACACTGTACCTTATGGAGTTCATTTAGCGTTAGTTAAGGTAGATAAAGAGACTGG
AAGTATAAGAGTGAGGAAATACATTGCCTTAGACGATGTTGGGAGAGTTATAAATCCACTACTTGCAGAAGGTCAGATAA
TTGGTGGGGCTTTACAAGGGATAGGACAAGCTATATATGAAGGAACAATATATAGTAAAGAGGGTTATTTGCTAAATTCA
AACTTAACCGACTATGGGTTTCCTACTGCAGTGGAAGCACCAAGGATTGAGTGGCATTACATTGAAAAGGGATTATCAGG
CCATCCTACTAATTCTAAAGGAATAGGCGAGGCTGGAGCTATTGCCTCAACTCCTGCTGTAGTAAATGCAGTAGAAAAGT
GCATTAGGAAGAAAATAGTTAACATGCCGATAAGACCAGAAGAGGTTATTTAA

Upstream 100 bases:

>100_bases
AAGATTTAATAACGAAATATGATATGAAAGAAACGACATTTTTATCTACACATCCAAATATTCACGTAAGACTTAAAAAC
ATCAACGAGTAGATTAGATT

Downstream 100 bases:

>100_bases
CTCATGCAAAGACATGTTATGTCATCTAAAGACTCTAAGATTTTTATCAACAAGATAAAAGAGAAGTATAATGTTGATAT
TTCTAATGCTAAATTAGAGG

Product: carbon monoxide dehydrogenase, large chain (cutA-8)

Products: NA

Alternate protein names: CO dehydrogenase subunit L; CO-DH L [H]

Number of amino acids: Translated: 710; Mature: 710

Protein sequence:

>710_residues
MYVGKPIKRIEDPKFLTGGSTYVDDIELPGTLFVAFLRSVKPHAKIKIKKNGNNVFTGYDINPGKDFPIPIEETTYVGQP
LAIVVGRDRYEAYDLLESIEVEYEELPYVIDPQDALKNDVKVYSKKESNIYEYKKWEGGNIEQSLKEADVVINGELYNQR
VIANPLETRGILAYFDGNRLNVWSSTQSAHYLRRNLMNFLGIDNIRVIQPDVGGAFGSKIIAHPEEYAIAKLALKMKRPL
KWIPTRSEEMQSAGHGRDKRLKFKVAVKRDGTILGIDGTLIADLGAPYPDANDDEIGNVHSTVRMLLGPYRIQNVRIEEY
AVNTNKAPTQSYRGAGRPEATYFIERIINIISLELGKDEFDIREKNLIRELPYKNALGITYDTGDYIGLLNKAREYYETL
KKEASTDECIGSSMYVEITAFGPWETARVLAKSDGKIMIITGSGPHGQGDGTAFAQIVADVLEIPIENIEVRWGDTDIIS
DGIGTWGSRTVTIGGSAMYKAAEELRRRLIEVSAKMLNADVEEVEYKNGIFSHKKSSKSFTIKEVIQNAYSMGYSLDVTY
VYNVTKPGYTVPYGVHLALVKVDKETGSIRVRKYIALDDVGRVINPLLAEGQIIGGALQGIGQAIYEGTIYSKEGYLLNS
NLTDYGFPTAVEAPRIEWHYIEKGLSGHPTNSKGIGEAGAIASTPAVVNAVEKCIRKKIVNMPIRPEEVI

Sequences:

>Translated_710_residues
MYVGKPIKRIEDPKFLTGGSTYVDDIELPGTLFVAFLRSVKPHAKIKIKKNGNNVFTGYDINPGKDFPIPIEETTYVGQP
LAIVVGRDRYEAYDLLESIEVEYEELPYVIDPQDALKNDVKVYSKKESNIYEYKKWEGGNIEQSLKEADVVINGELYNQR
VIANPLETRGILAYFDGNRLNVWSSTQSAHYLRRNLMNFLGIDNIRVIQPDVGGAFGSKIIAHPEEYAIAKLALKMKRPL
KWIPTRSEEMQSAGHGRDKRLKFKVAVKRDGTILGIDGTLIADLGAPYPDANDDEIGNVHSTVRMLLGPYRIQNVRIEEY
AVNTNKAPTQSYRGAGRPEATYFIERIINIISLELGKDEFDIREKNLIRELPYKNALGITYDTGDYIGLLNKAREYYETL
KKEASTDECIGSSMYVEITAFGPWETARVLAKSDGKIMIITGSGPHGQGDGTAFAQIVADVLEIPIENIEVRWGDTDIIS
DGIGTWGSRTVTIGGSAMYKAAEELRRRLIEVSAKMLNADVEEVEYKNGIFSHKKSSKSFTIKEVIQNAYSMGYSLDVTY
VYNVTKPGYTVPYGVHLALVKVDKETGSIRVRKYIALDDVGRVINPLLAEGQIIGGALQGIGQAIYEGTIYSKEGYLLNS
NLTDYGFPTAVEAPRIEWHYIEKGLSGHPTNSKGIGEAGAIASTPAVVNAVEKCIRKKIVNMPIRPEEVI
>Mature_710_residues
MYVGKPIKRIEDPKFLTGGSTYVDDIELPGTLFVAFLRSVKPHAKIKIKKNGNNVFTGYDINPGKDFPIPIEETTYVGQP
LAIVVGRDRYEAYDLLESIEVEYEELPYVIDPQDALKNDVKVYSKKESNIYEYKKWEGGNIEQSLKEADVVINGELYNQR
VIANPLETRGILAYFDGNRLNVWSSTQSAHYLRRNLMNFLGIDNIRVIQPDVGGAFGSKIIAHPEEYAIAKLALKMKRPL
KWIPTRSEEMQSAGHGRDKRLKFKVAVKRDGTILGIDGTLIADLGAPYPDANDDEIGNVHSTVRMLLGPYRIQNVRIEEY
AVNTNKAPTQSYRGAGRPEATYFIERIINIISLELGKDEFDIREKNLIRELPYKNALGITYDTGDYIGLLNKAREYYETL
KKEASTDECIGSSMYVEITAFGPWETARVLAKSDGKIMIITGSGPHGQGDGTAFAQIVADVLEIPIENIEVRWGDTDIIS
DGIGTWGSRTVTIGGSAMYKAAEELRRRLIEVSAKMLNADVEEVEYKNGIFSHKKSSKSFTIKEVIQNAYSMGYSLDVTY
VYNVTKPGYTVPYGVHLALVKVDKETGSIRVRKYIALDDVGRVINPLLAEGQIIGGALQGIGQAIYEGTIYSKEGYLLNS
NLTDYGFPTAVEAPRIEWHYIEKGLSGHPTNSKGIGEAGAIASTPAVVNAVEKCIRKKIVNMPIRPEEVI

Specific function: Catalyzes the oxidation of carbon monoxide to carbon dioxide [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI71773480, Length=776, Percent_Identity=23.3247422680412, Blast_Score=154, Evalue=4e-37,
Organism=Homo sapiens, GI91823271, Length=751, Percent_Identity=24.3675099866844, Blast_Score=152, Evalue=7e-37,
Organism=Escherichia coli, GI1789230, Length=750, Percent_Identity=25.4666666666667, Blast_Score=199, Evalue=4e-52,
Organism=Escherichia coli, GI1789246, Length=793, Percent_Identity=26.3556116015132, Blast_Score=194, Evalue=1e-50,
Organism=Escherichia coli, GI1786478, Length=591, Percent_Identity=23.3502538071066, Blast_Score=124, Evalue=3e-29,
Organism=Caenorhabditis elegans, GI17540638, Length=732, Percent_Identity=24.3169398907104, Blast_Score=154, Evalue=1e-37,
Organism=Caenorhabditis elegans, GI17539860, Length=752, Percent_Identity=24.7340425531915, Blast_Score=138, Evalue=8e-33,
Organism=Caenorhabditis elegans, GI32566215, Length=728, Percent_Identity=23.489010989011, Blast_Score=122, Evalue=8e-28,
Organism=Drosophila melanogaster, GI17737937, Length=750, Percent_Identity=25.3333333333333, Blast_Score=149, Evalue=7e-36,
Organism=Drosophila melanogaster, GI24647193, Length=682, Percent_Identity=25.6598240469208, Blast_Score=112, Evalue=6e-25,
Organism=Drosophila melanogaster, GI24647199, Length=694, Percent_Identity=23.9193083573487, Blast_Score=104, Evalue=2e-22,
Organism=Drosophila melanogaster, GI24647201, Length=736, Percent_Identity=22.554347826087, Blast_Score=85, Evalue=1e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000674
- InterPro:   IPR008274
- InterPro:   IPR012780 [H]

Pfam domain/function: PF01315 Ald_Xan_dh_C; PF02738 Ald_Xan_dh_C2 [H]

EC number: =1.2.99.2 [H]

Molecular weight: Translated: 79025; Mature: 79025

Theoretical pI: Translated: 6.09; Mature: 6.09

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYVGKPIKRIEDPKFLTGGSTYVDDIELPGTLFVAFLRSVKPHAKIKIKKNGNNVFTGYD
CCCCCCHHHCCCCCEEECCCCEEECCCCCHHHHHHHHHCCCCCEEEEEEECCCEEEEEEE
INPGKDFPIPIEETTYVGQPLAIVVGRDRYEAYDLLESIEVEYEELPYVIDPQDALKNDV
CCCCCCCCCCCCCCEECCCCEEEEEECCHHHHHHHHHHHCCCHHHCCEEECCHHHHCCCC
KVYSKKESNIYEYKKWEGGNIEQSLKEADVVINGELYNQRVIANPLETRGILAYFDGNRL
EEEECCCCCCEEEECCCCCCHHHHHHHCCEEEECCCCCCEEECCCCCCCCEEEEEECCEE
NVWSSTQSAHYLRRNLMNFLGIDNIRVIQPDVGGAFGSKIIAHPEEYAIAKLALKMKRPL
EEECCCHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCHHCCCHHHHHHHHHHHHHCCC
KWIPTRSEEMQSAGHGRDKRLKFKVAVKRDGTILGIDGTLIADLGAPYPDANDDEIGNVH
EECCCCHHHHHHCCCCCCCEEEEEEEEECCCEEEEECCEEEECCCCCCCCCCCCCCCHHH
STVRMLLGPYRIQNVRIEEYAVNTNKAPTQSYRGAGRPEATYFIERIINIISLELGKDEF
HHHHHHHCCCEEEEEEEEEEEECCCCCCCHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCC
DIREKNLIRELPYKNALGITYDTGDYIGLLNKAREYYETLKKEASTDECIGSSMYVEITA
CHHHHHHHHHCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHCCCCHHHCCCCEEEEEEE
FGPWETARVLAKSDGKIMIITGSGPHGQGDGTAFAQIVADVLEIPIENIEVRWGDTDIIS
ECCCHHHHHEECCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHCCCCCEEEEECCCHHHC
DGIGTWGSRTVTIGGSAMYKAAEELRRRLIEVSAKMLNADVEEVEYKNGIFSHKKSSKSF
CCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCCCCCCE
TIKEVIQNAYSMGYSLDVTYVYNVTKPGYTVPYGVHLALVKVDKETGSIRVRKYIALDDV
EHHHHHHHHHHCCCEEEEEEEEEECCCCCCCCCCEEEEEEEEECCCCCEEEEEEEEHHHH
GRVINPLLAEGQIIGGALQGIGQAIYEGTIYSKEGYLLNSNLTDYGFPTAVEAPRIEWHY
HHHHHHHHHCCEEEHHHHHHHHHHHHCCEEECCCCEEEECCCCCCCCCCCCCCCCCEEHH
IEKGLSGHPTNSKGIGEAGAIASTPAVVNAVEKCIRKKIVNMPIRPEEVI
HHCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCHHCCC
>Mature Secondary Structure
MYVGKPIKRIEDPKFLTGGSTYVDDIELPGTLFVAFLRSVKPHAKIKIKKNGNNVFTGYD
CCCCCCHHHCCCCCEEECCCCEEECCCCCHHHHHHHHHCCCCCEEEEEEECCCEEEEEEE
INPGKDFPIPIEETTYVGQPLAIVVGRDRYEAYDLLESIEVEYEELPYVIDPQDALKNDV
CCCCCCCCCCCCCCEECCCCEEEEEECCHHHHHHHHHHHCCCHHHCCEEECCHHHHCCCC
KVYSKKESNIYEYKKWEGGNIEQSLKEADVVINGELYNQRVIANPLETRGILAYFDGNRL
EEEECCCCCCEEEECCCCCCHHHHHHHCCEEEECCCCCCEEECCCCCCCCEEEEEECCEE
NVWSSTQSAHYLRRNLMNFLGIDNIRVIQPDVGGAFGSKIIAHPEEYAIAKLALKMKRPL
EEECCCHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCHHCCCHHHHHHHHHHHHHCCC
KWIPTRSEEMQSAGHGRDKRLKFKVAVKRDGTILGIDGTLIADLGAPYPDANDDEIGNVH
EECCCCHHHHHHCCCCCCCEEEEEEEEECCCEEEEECCEEEECCCCCCCCCCCCCCCHHH
STVRMLLGPYRIQNVRIEEYAVNTNKAPTQSYRGAGRPEATYFIERIINIISLELGKDEF
HHHHHHHCCCEEEEEEEEEEEECCCCCCCHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCC
DIREKNLIRELPYKNALGITYDTGDYIGLLNKAREYYETLKKEASTDECIGSSMYVEITA
CHHHHHHHHHCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHCCCCHHHCCCCEEEEEEE
FGPWETARVLAKSDGKIMIITGSGPHGQGDGTAFAQIVADVLEIPIENIEVRWGDTDIIS
ECCCHHHHHEECCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHCCCCCEEEEECCCHHHC
DGIGTWGSRTVTIGGSAMYKAAEELRRRLIEVSAKMLNADVEEVEYKNGIFSHKKSSKSF
CCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCCCCCCE
TIKEVIQNAYSMGYSLDVTYVYNVTKPGYTVPYGVHLALVKVDKETGSIRVRKYIALDDV
EHHHHHHHHHHCCCEEEEEEEEEECCCCCCCCCCEEEEEEEEECCCCCEEEEEEEEHHHH
GRVINPLLAEGQIIGGALQGIGQAIYEGTIYSKEGYLLNSNLTDYGFPTAVEAPRIEWHY
HHHHHHHHHCCEEEHHHHHHHHHHHHCCEEECCCCEEEECCCCCCCCCCCCCCCCCEEHH
IEKGLSGHPTNSKGIGEAGAIASTPAVVNAVEKCIRKKIVNMPIRPEEVI
HHCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10482497; 2818128; 10966817; 11076018 [H]