Click here to switch to the map view.

The map label for this gene is gabT-2 [H]

Identifier: 15899912

GI number: 15899912

Start: 2957760

End: 2959016

Strand: Direct

Name: gabT-2 [H]

Synonym: SSO3211

Alternate gene names: 15899912

Gene position: 2957760-2959016 (Clockwise)

Preceding gene: 15899908

Following gene: 15899914

Centisome position: 98.85

GC content: 37.23

Gene sequence:

>1257_bases
ATGAGCAAGAAAGTAGATGAGTTGATAAAAGAGGATCAAGAATATTTGATGCAATCCTTTAGGAGATGGTATCCATTTGT
AATAGATCACGGTTTTGGGGCAATAGTTTACGATATTGAAGGAAACGAGTACATTGATTTTAACGCGGGAATAGGAGTAG
TTGCATTAGGCCACAAAAACGAGAAGATCATTAATGCAGTAAAGGAGCAAATGGACAAGTTTTTCCATTATAGTCTTACA
GATTTCTACTATGAAGTTGCGATAGAAGTAGCGAAAAGATTATCCTCCTTAATGCCATTCTCAGCTAAGGTATTTTATGC
TAACAGTGGTACTGAGAGTGTTGAAGCAGCAATAAAGATAGCTAGAGGGCATACAGGGAGACAATGGATTATAGGTTTCA
TTAATTCCTTTCATGGAAGAACCTTAGGCTCCTTAGCCTTTACCTCAAGTAAAGCTATCCAAAGGAAATCGTTCTCTCCC
CTTTTACCATCAACATATTTAATCCCATATCCAGATAGGAGAGACCCACTATGTAAAGAAGAGTGTACTGAAGAGTTGTT
AGGATTTATAGAAGACTGGGTTTTCAAGAAGGTAGTCGATCCCAATGAAGTAGCTGCTTTTATTGCTGAGCCAATACAAG
GAGAAGGTGGGGTTATAGTACCTCCTAAGGATTTCTTTTATAAATTGAATAATTTACTTAAGAAATTTGGAATCTTACTT
ATCCTTGATGAAGTACAGACTGGAATCGGAAGAACTGGGAAAATGTTCGCATTTGAGCATTTCAATGTAACGCCAGATTT
AGTATGTTTAGCTAAGGCATTAGGTGGAGGACTTCCACTGGGTGCAGTTGTTGGAAGAAAGGAGATTATGGATTTGCCTC
CGGGTTCTCATGCTAACACTTTTGGGGGAAATCCATTAGCATTGGCTGCAGCGAATGTTATTTTAGAAGAGGTTCCGAAG
CTATTAGACCATGTAAGCAGTATAGGCAAGAAAATTATCGAGGAACTAACAGATACTAGATCACCTTACTTATATGATGT
CAGAGGATTAGGTCTTCTCATAGGTGCTGAGTTAAGAAAAAATGATAAACCATTTGTAGAAGGTCTAGAAAAAGTATTAT
ATAATTCTTTCAGAAGAGGAGTATTGGCAATAGGAGCTGGAGAATCGGTAGTTAGAATAGAACCTCCGCTAATAATAAGT
GAAGAGTTGGCCATGAAAGGTACTAAAATATTAAAGGAAGAAATAGAAAAACTTTAA

Upstream 100 bases:

>100_bases
AAAGATCGATAATTTATTGTATTACGAAAAACGAATAGTGAGTATTGTTACTTTAAGAAACTAGGAAAAATTAATATACT
ATAAGTTCGAAATTAAAACG

Downstream 100 bases:

>100_bases
CTTTTCTTTTCTACAAAGATTAGTATTAACGATAATACTATTAGGATGACATCGAGAGCTAAGGAGATATCTACATAATA
ATTAAATGGAAGTTTCTTTC

Product: 4-aminobutyrate aminotransferase

Products: NA

Alternate protein names: ACOAT [H]

Number of amino acids: Translated: 418; Mature: 417

Protein sequence:

>418_residues
MSKKVDELIKEDQEYLMQSFRRWYPFVIDHGFGAIVYDIEGNEYIDFNAGIGVVALGHKNEKIINAVKEQMDKFFHYSLT
DFYYEVAIEVAKRLSSLMPFSAKVFYANSGTESVEAAIKIARGHTGRQWIIGFINSFHGRTLGSLAFTSSKAIQRKSFSP
LLPSTYLIPYPDRRDPLCKEECTEELLGFIEDWVFKKVVDPNEVAAFIAEPIQGEGGVIVPPKDFFYKLNNLLKKFGILL
ILDEVQTGIGRTGKMFAFEHFNVTPDLVCLAKALGGGLPLGAVVGRKEIMDLPPGSHANTFGGNPLALAAANVILEEVPK
LLDHVSSIGKKIIEELTDTRSPYLYDVRGLGLLIGAELRKNDKPFVEGLEKVLYNSFRRGVLAIGAGESVVRIEPPLIIS
EELAMKGTKILKEEIEKL

Sequences:

>Translated_418_residues
MSKKVDELIKEDQEYLMQSFRRWYPFVIDHGFGAIVYDIEGNEYIDFNAGIGVVALGHKNEKIINAVKEQMDKFFHYSLT
DFYYEVAIEVAKRLSSLMPFSAKVFYANSGTESVEAAIKIARGHTGRQWIIGFINSFHGRTLGSLAFTSSKAIQRKSFSP
LLPSTYLIPYPDRRDPLCKEECTEELLGFIEDWVFKKVVDPNEVAAFIAEPIQGEGGVIVPPKDFFYKLNNLLKKFGILL
ILDEVQTGIGRTGKMFAFEHFNVTPDLVCLAKALGGGLPLGAVVGRKEIMDLPPGSHANTFGGNPLALAAANVILEEVPK
LLDHVSSIGKKIIEELTDTRSPYLYDVRGLGLLIGAELRKNDKPFVEGLEKVLYNSFRRGVLAIGAGESVVRIEPPLIIS
EELAMKGTKILKEEIEKL
>Mature_417_residues
SKKVDELIKEDQEYLMQSFRRWYPFVIDHGFGAIVYDIEGNEYIDFNAGIGVVALGHKNEKIINAVKEQMDKFFHYSLTD
FYYEVAIEVAKRLSSLMPFSAKVFYANSGTESVEAAIKIARGHTGRQWIIGFINSFHGRTLGSLAFTSSKAIQRKSFSPL
LPSTYLIPYPDRRDPLCKEECTEELLGFIEDWVFKKVVDPNEVAAFIAEPIQGEGGVIVPPKDFFYKLNNLLKKFGILLI
LDEVQTGIGRTGKMFAFEHFNVTPDLVCLAKALGGGLPLGAVVGRKEIMDLPPGSHANTFGGNPLALAAANVILEEVPKL
LDHVSSIGKKIIEELTDTRSPYLYDVRGLGLLIGAELRKNDKPFVEGLEKVLYNSFRRGVLAIGAGESVVRIEPPLIISE
ELAMKGTKILKEEIEKL

Specific function: Unknown

COG id: COG0160

COG function: function code E; 4-aminobutyrate aminotransferase and related aminotransferases

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily [H]

Homologues:

Organism=Homo sapiens, GI4557809, Length=424, Percent_Identity=33.9622641509434, Blast_Score=189, Evalue=3e-48,
Organism=Homo sapiens, GI13994255, Length=410, Percent_Identity=30.4878048780488, Blast_Score=176, Evalue=5e-44,
Organism=Homo sapiens, GI37574042, Length=395, Percent_Identity=30.379746835443, Blast_Score=158, Evalue=7e-39,
Organism=Homo sapiens, GI226442705, Length=397, Percent_Identity=30.4785894206549, Blast_Score=155, Evalue=9e-38,
Organism=Homo sapiens, GI226442709, Length=375, Percent_Identity=30.6666666666667, Blast_Score=154, Evalue=2e-37,
Organism=Homo sapiens, GI24119277, Length=446, Percent_Identity=27.5784753363229, Blast_Score=154, Evalue=2e-37,
Organism=Homo sapiens, GI284507298, Length=322, Percent_Identity=35.4037267080745, Blast_Score=147, Evalue=2e-35,
Organism=Homo sapiens, GI188536080, Length=421, Percent_Identity=28.0285035629454, Blast_Score=114, Evalue=2e-25,
Organism=Homo sapiens, GI38679950, Length=421, Percent_Identity=28.0285035629454, Blast_Score=114, Evalue=2e-25,
Organism=Homo sapiens, GI38679946, Length=421, Percent_Identity=28.0285035629454, Blast_Score=114, Evalue=2e-25,
Organism=Escherichia coli, GI1787560, Length=396, Percent_Identity=36.6161616161616, Blast_Score=249, Evalue=2e-67,
Organism=Escherichia coli, GI1789016, Length=419, Percent_Identity=32.6968973747017, Blast_Score=227, Evalue=1e-60,
Organism=Escherichia coli, GI145693181, Length=428, Percent_Identity=37.6168224299065, Blast_Score=226, Evalue=2e-60,
Organism=Escherichia coli, GI1788044, Length=417, Percent_Identity=36.4508393285372, Blast_Score=226, Evalue=3e-60,
Organism=Escherichia coli, GI1789759, Length=408, Percent_Identity=35.2941176470588, Blast_Score=222, Evalue=3e-59,
Organism=Escherichia coli, GI1786349, Length=319, Percent_Identity=33.2288401253918, Blast_Score=159, Evalue=4e-40,
Organism=Escherichia coli, GI1786991, Length=347, Percent_Identity=30.835734870317, Blast_Score=138, Evalue=7e-34,
Organism=Caenorhabditis elegans, GI25144271, Length=400, Percent_Identity=32.75, Blast_Score=190, Evalue=1e-48,
Organism=Caenorhabditis elegans, GI32564660, Length=426, Percent_Identity=32.8638497652582, Blast_Score=185, Evalue=3e-47,
Organism=Caenorhabditis elegans, GI71992977, Length=445, Percent_Identity=27.8651685393258, Blast_Score=157, Evalue=9e-39,
Organism=Caenorhabditis elegans, GI25144274, Length=282, Percent_Identity=33.6879432624113, Blast_Score=144, Evalue=1e-34,
Organism=Caenorhabditis elegans, GI17541228, Length=448, Percent_Identity=25.2232142857143, Blast_Score=108, Evalue=5e-24,
Organism=Caenorhabditis elegans, GI71981843, Length=157, Percent_Identity=31.2101910828025, Blast_Score=68, Evalue=7e-12,
Organism=Saccharomyces cerevisiae, GI6324432, Length=427, Percent_Identity=33.7236533957845, Blast_Score=209, Evalue=8e-55,
Organism=Saccharomyces cerevisiae, GI6323470, Length=438, Percent_Identity=33.3333333333333, Blast_Score=201, Evalue=2e-52,
Organism=Saccharomyces cerevisiae, GI6324386, Length=471, Percent_Identity=25.4777070063694, Blast_Score=111, Evalue=2e-25,
Organism=Saccharomyces cerevisiae, GI6321456, Length=427, Percent_Identity=26.463700234192, Blast_Score=107, Evalue=4e-24,
Organism=Drosophila melanogaster, GI21357415, Length=405, Percent_Identity=34.0740740740741, Blast_Score=179, Evalue=2e-45,
Organism=Drosophila melanogaster, GI28574759, Length=417, Percent_Identity=32.6139088729017, Blast_Score=173, Evalue=2e-43,
Organism=Drosophila melanogaster, GI161085790, Length=419, Percent_Identity=32.2195704057279, Blast_Score=171, Evalue=1e-42,
Organism=Drosophila melanogaster, GI21356575, Length=422, Percent_Identity=30.8056872037915, Blast_Score=168, Evalue=5e-42,
Organism=Drosophila melanogaster, GI281366494, Length=426, Percent_Identity=27.2300469483568, Blast_Score=111, Evalue=1e-24,
Organism=Drosophila melanogaster, GI24667139, Length=426, Percent_Identity=27.2300469483568, Blast_Score=111, Evalue=1e-24,
Organism=Drosophila melanogaster, GI24667143, Length=426, Percent_Identity=27.2300469483568, Blast_Score=111, Evalue=1e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004636
- InterPro:   IPR005814
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00202 Aminotran_3 [H]

EC number: =2.6.1.11 [H]

Molecular weight: Translated: 46522; Mature: 46391

Theoretical pI: Translated: 6.14; Mature: 6.14

Prosite motif: PS00600 AA_TRANSFER_CLASS_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKKVDELIKEDQEYLMQSFRRWYPFVIDHGFGAIVYDIEGNEYIDFNAGIGVVALGHKN
CCHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCEEEEEECCCEEEEECCCCCEEEECCCC
EKIINAVKEQMDKFFHYSLTDFYYEVAIEVAKRLSSLMPFSAKVFYANSGTESVEAAIKI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHH
ARGHTGRQWIIGFINSFHGRTLGSLAFTSSKAIQRKSFSPLLPSTYLIPYPDRRDPLCKE
HCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCCEEECCCCCCCCCHHH
ECTEELLGFIEDWVFKKVVDPNEVAAFIAEPIQGEGGVIVPPKDFFYKLNNLLKKFGILL
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCEEECCHHHHHHHHHHHHHHHHEE
ILDEVQTGIGRTGKMFAFEHFNVTPDLVCLAKALGGGLPLGAVVGRKEIMDLPPGSHANT
EEHHHHHCCCCCCCEEEEECCCCCHHHHHHHHHHCCCCCHHHHHCHHHHHCCCCCCCCCC
FGGNPLALAAANVILEEVPKLLDHVSSIGKKIIEELTDTRSPYLYDVRGLGLLIGAELRK
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCHHEEEHHHCC
NDKPFVEGLEKVLYNSFRRGVLAIGAGESVVRIEPPLIISEELAMKGTKILKEEIEKL
CCCHHHHHHHHHHHHHHCCCEEEEECCCCEEEECCCEEECHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SKKVDELIKEDQEYLMQSFRRWYPFVIDHGFGAIVYDIEGNEYIDFNAGIGVVALGHKN
CHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCEEEEEECCCEEEEECCCCCEEEECCCC
EKIINAVKEQMDKFFHYSLTDFYYEVAIEVAKRLSSLMPFSAKVFYANSGTESVEAAIKI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHH
ARGHTGRQWIIGFINSFHGRTLGSLAFTSSKAIQRKSFSPLLPSTYLIPYPDRRDPLCKE
HCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCCEEECCCCCCCCCHHH
ECTEELLGFIEDWVFKKVVDPNEVAAFIAEPIQGEGGVIVPPKDFFYKLNNLLKKFGILL
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCEEECCHHHHHHHHHHHHHHHHEE
ILDEVQTGIGRTGKMFAFEHFNVTPDLVCLAKALGGGLPLGAVVGRKEIMDLPPGSHANT
EEHHHHHCCCCCCCEEEEECCCCCHHHHHHHHHHCCCCCHHHHHCHHHHHCCCCCCCCCC
FGGNPLALAAANVILEEVPKLLDHVSSIGKKIIEELTDTRSPYLYDVRGLGLLIGAELRK
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCHHEEEHHHCC
NDKPFVEGLEKVLYNSFRRGVLAIGAGESVVRIEPPLIISEELAMKGTKILKEEIEKL
CCCHHHHHHHHHHHHHHCCCEEEEECCCCEEEECCCEEECHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11058132 [H]