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The map label for this gene is guaB [C]

Identifier: 15899877

GI number: 15899877

Start: 2920754

End: 2921149

Strand: Direct

Name: guaB [C]

Synonym: SSO3174

Alternate gene names: 15899877

Gene position: 2920754-2921149 (Clockwise)

Preceding gene: 15899876

Following gene: 15899878

Centisome position: 97.61

GC content: 37.37

Gene sequence:

>396_bases
ATGTATGTAGCCGATTTGATTACCAGAAACCCGCTTACAGTCAAGCCCGAAACAAGTATAAGAGATGCTGCTAAGATTAT
GAAAAGGGAAAATCTAGGTTCTCTTATAATAGTAGATGAGACAAATAAGCCAATTGGGATAGTTACTGAAAGGGATATTT
TAAGGGCAGTAGCAGATGAAGTAGCATTAGATTCTCCCGTTTCTACAATCATGACAAGAGGTTTGATAACCATTCCTCCA
AATAAGGATGTTACAGAGGCATTAATTATCATGTATCAAAATAACGTTAGACATCTAGCAGTAGTTGGACAAAGCGGGGA
ATTAGTCGGAGTAATATCTATTAGAGATGCTGCCAAGGCAGTAAATCTTTTGGCACTTGATCTATCAATATGGTGA

Upstream 100 bases:

>100_bases
ATAGGGCAGAAGAAATTAGGGTTCCCGCTTGGCATGATGTTATATGATATTTCCTTTTTTAGAGAAAAAATAAATAGTCT
AATACACTTACTATAATATT

Downstream 100 bases:

>100_bases
GTTACCTTATCTAAGTAAATTGTTAAAACTATAATGAATTAAATATTGACAACAATCTAATTCCACACTATAAATATTTT
TTAATACGAATTTAGTAGAT

Product: hypothetical protein

Products: H+; Nicotinamide adenine dinucleotide - reduced; Xanthosine 5'-phosphate [C]

Alternate protein names: ORF3 [H]

Number of amino acids: Translated: 131; Mature: 131

Protein sequence:

>131_residues
MYVADLITRNPLTVKPETSIRDAAKIMKRENLGSLIIVDETNKPIGIVTERDILRAVADEVALDSPVSTIMTRGLITIPP
NKDVTEALIIMYQNNVRHLAVVGQSGELVGVISIRDAAKAVNLLALDLSIW

Sequences:

>Translated_131_residues
MYVADLITRNPLTVKPETSIRDAAKIMKRENLGSLIIVDETNKPIGIVTERDILRAVADEVALDSPVSTIMTRGLITIPP
NKDVTEALIIMYQNNVRHLAVVGQSGELVGVISIRDAAKAVNLLALDLSIW
>Mature_131_residues
MYVADLITRNPLTVKPETSIRDAAKIMKRENLGSLIIVDETNKPIGIVTERDILRAVADEVALDSPVSTIMTRGLITIPP
NKDVTEALIIMYQNNVRHLAVVGQSGELVGVISIRDAAKAVNLLALDLSIW

Specific function: GMP biosynthesis from IMP; first step. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 CBS domains [H]

Homologues:

None

Paralogues:

None

Copy number: 600 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR000644 [H]

Pfam domain/function: PF00571 CBS [H]

EC number: 1.1.1.205 [C]

Molecular weight: Translated: 14286; Mature: 14286

Theoretical pI: Translated: 5.17; Mature: 5.17

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYVADLITRNPLTVKPETSIRDAAKIMKRENLGSLIIVDETNKPIGIVTERDILRAVADE
CCCHHHHCCCCEEECCCCCHHHHHHHHHHCCCCCEEEEECCCCCEEEEEHHHHHHHHHHH
VALDSPVSTIMTRGLITIPPNKDVTEALIIMYQNNVRHLAVVGQSGELVGVISIRDAAKA
HCCCCCHHHHHHCCEEEECCCCCCCCEEEEEEECCCEEEEEECCCCCEEEEEEECCHHHH
VNLLALDLSIW
HEEEEEEEECC
>Mature Secondary Structure
MYVADLITRNPLTVKPETSIRDAAKIMKRENLGSLIIVDETNKPIGIVTERDILRAVADE
CCCHHHHCCCCEEECCCCCHHHHHHHHHHCCCCCEEEEECCCCCEEEEEHHHHHHHHHHH
VALDSPVSTIMTRGLITIPPNKDVTEALIIMYQNNVRHLAVVGQSGELVGVISIRDAAKA
HCCCCCHHHHHHCCEEEECCCCCCCCEEEEEEECCCEEEEEECCCCCEEEEEEECCHHHH
VNLLALDLSIW
HEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NAD+ [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: H2O; IMP; Nicotinamide adenine dinucleotide [C]

Specific reaction: H2O + IMP + Nicotinamide adenine dinucleotide --> H+ + Nicotinamide adenine dinucleotide - reduced + Xanthosine 5'-phosphate [C]

General reaction: Redox reaction [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA