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The map label for this gene is cysI [H]

Identifier: 15899623

GI number: 15899623

Start: 2659937

End: 2661829

Strand: Reverse

Name: cysI [H]

Synonym: SSO2909

Alternate gene names: 15899623

Gene position: 2661829-2659937 (Counterclockwise)

Preceding gene: 15899624

Following gene: 15899622

Centisome position: 88.96

GC content: 37.61

Gene sequence:

>1893_bases
GTGAAGATTCCCATAGAGCCCAATTTTAGAACAGATCCTAAAGATTACAGTGAGGAAGAGAGAGCAAAGCTGAAAACTAA
AGGATTAACTGAGGATACAATAGGAATATATTCGTCATTCCACGACTTATCTAGAGAAGATCTCGAGAAGGAAGTGTCCT
TGATAGCTAAAAGTTTCGGGATATACATTGAATTCAATAGAGATAAGATGAAATTAAATGGAGTCAAAGATTGGATATAC
ATGGTAAGGCTACCGATTCCCGGAGGAGGTCCAATAAGCTCTAAACAATGGAGAATTTTAGACGATATTTCCAACAAATA
TACGATATCGGATGCTTATACTGGATATCCCTCACCATCTCTAAAACTGACTACGAGACAAGCTATTCAATTTCACCACG
TAAAGAAAAGGGATTTACCTAACCTTATAAGAGAGGTCGCTGAATCTGGTTTTCTCACTGTAAACGGTTGTGGAGATAAT
GTAAGGAATACGATAGCTTGCCCACTTTCCAAGTATTGGGTTTTCGACGCGAATTCATTAGCTAGAAAAATTGCTAACTA
CTTTAGATTACCTTTGGATTTATATCTTCAAGTCTTTGAAATACCTCTGATAGAAAATAGACAATTTGATAGAGAATCTT
TCAAATATGGTGAAAATCTTTTACCGAGAAAGTTTAAGATCGCCATAGCGGGGGTATTGAGAACAATTAACGGAAAGTAT
ATAATTGATAATTGCGTTGAAGTTCAATCCAACGATATAGGCATAGTCCCTTTAATAGAGGATGAAAAGGTAATAGGTTA
TCAAATATACGTTGGTGGATCAATGGGTGAGAACAATTCTTATCCAACTTTTTCGGCTCTTGGACTTCCGATTGGTACTG
TAGTAAACGATAGCGAATTAATAAAGGTGTTAGATGCTATTGTGACAATACAAGAGGAGTGGGGAGATAGGAAGAACAGG
CATTGGGCTAGATTCAAGTACGTTGTATATAAGATGGGATTGGAGTGGTTAAGGGAAAAAGTAAGGGAACACTCTGGGAT
ACAATTAGGCAAAATAGTTAAAGTAGATCTCACCCACAAGGACTTACATTTGGGTTGGATAAATTTAGGCGATAATAAGT
GGGCTTATGGTATTTTCGTTGAAAACGGTAGGCTAATAGACGGCAAAAACGGTAGGACAAAAAGTATGATCAGATATATT
GCAGATAATTTCGATAATTTAATGTTTTACATAACTCCAAATCAACATCTATTAATTACTGAAATAGACCAGCCGCAGAA
GGAGAAAATCGATGGGATACTTAGGGAGTTCAACTACGGATTCAGAGACGGAAAGCCATATTCCAGTTTAAGGATTAACT
CAACGGCGTGCGTAGGATTTCCAACATGTAAATTGTCCTTCACTGATTCTGAAAGATTCCTTCCAAGTCTAATTGACGAG
TTAGAGAGAAGAGGGTGGAAAGACATTCCAGTTTCAATAGGACTGTCAGGTTGTGTAGCTCAGTGTTCAAGACCAGCCCT
TCATCCCATTAGTTGGGTAGGTAGTGGATATGAGCTTTACATGTTAAAGATAGGTGGAGGAAATGGAAGTTTAGGAGAAC
CACTAATTGACTGGGACGAGAATTCTATTTACCTATATCAAGTTCCGTCCAATAGACTAGCTGATGTAACTGAAGCGTTA
TTTGAACTATACGAAAAGAATAAGGATATAAGTGAAGATCCTAGTCTAGTATTTAGGTTGCTGGGTAATAAGAAGATAAT
TGAGTGGTTGAAGGGTCACGAAAAGACTAAAGACCTCATGAAACCTCACAAGTTTGATAGAAAGATTGAGGGCTATAGGG
AGTATCACGATCTGCTAAGAAAACGTTTAGAGGAGGTGAGTAGATATGGGTAA

Upstream 100 bases:

>100_bases
GTACTAGACCAGTTAAACCTTGGGAGCATCCAAGAGCTGGTAGATGGTGGTGGGAGCAGAATAGTGACAAGGAATGTGGG
CTTCATTATAGAGAGGTGAA

Downstream 100 bases:

>100_bases
GGTAGTTTTAGTAGGTGCTGGTCCTGGTGATCCTGAACTAATAACGTTAAAGGGTATTAAATATTTACAAATGGCTGATG
TAATAGTCTACGATAAGTTA

Product: sulfite reductase hemoprotein beta component (cysI)

Products: NA

Alternate protein names: SiR-HP; SiRHP [H]

Number of amino acids: Translated: 630; Mature: 630

Protein sequence:

>630_residues
MKIPIEPNFRTDPKDYSEEERAKLKTKGLTEDTIGIYSSFHDLSREDLEKEVSLIAKSFGIYIEFNRDKMKLNGVKDWIY
MVRLPIPGGGPISSKQWRILDDISNKYTISDAYTGYPSPSLKLTTRQAIQFHHVKKRDLPNLIREVAESGFLTVNGCGDN
VRNTIACPLSKYWVFDANSLARKIANYFRLPLDLYLQVFEIPLIENRQFDRESFKYGENLLPRKFKIAIAGVLRTINGKY
IIDNCVEVQSNDIGIVPLIEDEKVIGYQIYVGGSMGENNSYPTFSALGLPIGTVVNDSELIKVLDAIVTIQEEWGDRKNR
HWARFKYVVYKMGLEWLREKVREHSGIQLGKIVKVDLTHKDLHLGWINLGDNKWAYGIFVENGRLIDGKNGRTKSMIRYI
ADNFDNLMFYITPNQHLLITEIDQPQKEKIDGILREFNYGFRDGKPYSSLRINSTACVGFPTCKLSFTDSERFLPSLIDE
LERRGWKDIPVSIGLSGCVAQCSRPALHPISWVGSGYELYMLKIGGGNGSLGEPLIDWDENSIYLYQVPSNRLADVTEAL
FELYEKNKDISEDPSLVFRLLGNKKIIEWLKGHEKTKDLMKPHKFDRKIEGYREYHDLLRKRLEEVSRYG

Sequences:

>Translated_630_residues
MKIPIEPNFRTDPKDYSEEERAKLKTKGLTEDTIGIYSSFHDLSREDLEKEVSLIAKSFGIYIEFNRDKMKLNGVKDWIY
MVRLPIPGGGPISSKQWRILDDISNKYTISDAYTGYPSPSLKLTTRQAIQFHHVKKRDLPNLIREVAESGFLTVNGCGDN
VRNTIACPLSKYWVFDANSLARKIANYFRLPLDLYLQVFEIPLIENRQFDRESFKYGENLLPRKFKIAIAGVLRTINGKY
IIDNCVEVQSNDIGIVPLIEDEKVIGYQIYVGGSMGENNSYPTFSALGLPIGTVVNDSELIKVLDAIVTIQEEWGDRKNR
HWARFKYVVYKMGLEWLREKVREHSGIQLGKIVKVDLTHKDLHLGWINLGDNKWAYGIFVENGRLIDGKNGRTKSMIRYI
ADNFDNLMFYITPNQHLLITEIDQPQKEKIDGILREFNYGFRDGKPYSSLRINSTACVGFPTCKLSFTDSERFLPSLIDE
LERRGWKDIPVSIGLSGCVAQCSRPALHPISWVGSGYELYMLKIGGGNGSLGEPLIDWDENSIYLYQVPSNRLADVTEAL
FELYEKNKDISEDPSLVFRLLGNKKIIEWLKGHEKTKDLMKPHKFDRKIEGYREYHDLLRKRLEEVSRYG
>Mature_630_residues
MKIPIEPNFRTDPKDYSEEERAKLKTKGLTEDTIGIYSSFHDLSREDLEKEVSLIAKSFGIYIEFNRDKMKLNGVKDWIY
MVRLPIPGGGPISSKQWRILDDISNKYTISDAYTGYPSPSLKLTTRQAIQFHHVKKRDLPNLIREVAESGFLTVNGCGDN
VRNTIACPLSKYWVFDANSLARKIANYFRLPLDLYLQVFEIPLIENRQFDRESFKYGENLLPRKFKIAIAGVLRTINGKY
IIDNCVEVQSNDIGIVPLIEDEKVIGYQIYVGGSMGENNSYPTFSALGLPIGTVVNDSELIKVLDAIVTIQEEWGDRKNR
HWARFKYVVYKMGLEWLREKVREHSGIQLGKIVKVDLTHKDLHLGWINLGDNKWAYGIFVENGRLIDGKNGRTKSMIRYI
ADNFDNLMFYITPNQHLLITEIDQPQKEKIDGILREFNYGFRDGKPYSSLRINSTACVGFPTCKLSFTDSERFLPSLIDE
LERRGWKDIPVSIGLSGCVAQCSRPALHPISWVGSGYELYMLKIGGGNGSLGEPLIDWDENSIYLYQVPSNRLADVTEAL
FELYEKNKDISEDPSLVFRLLGNKKIIEWLKGHEKTKDLMKPHKFDRKIEGYREYHDLLRKRLEEVSRYG

Specific function: Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate [H]

COG id: COG0155

COG function: function code P; Sulfite reductase, beta subunit (hemoprotein)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nitrite and sulfite reductase 4Fe-4S domain family [H]

Homologues:

Organism=Escherichia coli, GI1789122, Length=486, Percent_Identity=28.3950617283951, Blast_Score=193, Evalue=4e-50,
Organism=Saccharomyces cerevisiae, GI6322597, Length=553, Percent_Identity=31.1030741410488, Blast_Score=211, Evalue=3e-55,

Paralogues:

None

Copy number: 640 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011786
- InterPro:   IPR005117
- InterPro:   IPR006067
- InterPro:   IPR006066 [H]

Pfam domain/function: PF01077 NIR_SIR; PF03460 NIR_SIR_ferr [H]

EC number: =1.8.1.2 [H]

Molecular weight: Translated: 72475; Mature: 72475

Theoretical pI: Translated: 8.04; Mature: 8.04

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIPIEPNFRTDPKDYSEEERAKLKTKGLTEDTIGIYSSFHDLSREDLEKEVSLIAKSFG
CCCCCCCCCCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHCC
IYIEFNRDKMKLNGVKDWIYMVRLPIPGGGPISSKQWRILDDISNKYTISDAYTGYPSPS
EEEEECCCEEEECCCEEEEEEEEEECCCCCCCCCCCEEEHHCCCCCEEECCCCCCCCCCC
LKLTTRQAIQFHHVKKRDLPNLIREVAESGFLTVNGCGDNVRNTIACPLSKYWVFDANSL
EEEEHHHHHHHHHHHHCCHHHHHHHHHHCCCEEEECCCCCCCCEEECCCCEEEEECCHHH
ARKIANYFRLPLDLYLQVFEIPLIENRQFDRESFKYGENLLPRKFKIAIAGVLRTINGKY
HHHHHHHHCCCHHHHHHHHHCCCCCCCCCCHHHHHHCCCCCCCHHHHHHHHHHHHCCCCE
IIDNCVEVQSNDIGIVPLIEDEKVIGYQIYVGGSMGENNSYPTFSALGLPIGTVVNDSEL
EEECEEEECCCCEEEEEEECCCEEEEEEEEECCCCCCCCCCCCCCCCCCCCCEEECHHHH
IKVLDAIVTIQEEWGDRKNRHWARFKYVVYKMGLEWLREKVREHSGIQLGKIVKVDLTHK
HHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEECCEEEEEECCC
DLHLGWINLGDNKWAYGIFVENGRLIDGKNGRTKSMIRYIADNFDNLMFYITPNQHLLIT
EEEEEEEEECCCCEEEEEEEECCEEEECCCCCHHHHHHHHHCCCCCEEEEECCCCEEEEE
EIDQPQKEKIDGILREFNYGFRDGKPYSSLRINSTACVGFPTCKLSFTDSERFLPSLIDE
ECCCCHHHHHHHHHHHHCCCCCCCCCCCEEEECCEEEEECCEEEEEECCCHHHHHHHHHH
LERRGWKDIPVSIGLSGCVAQCSRPALHPISWVGSGYELYMLKIGGGNGSLGEPLIDWDE
HHHCCCCCCCEECCCHHHHHHCCCCCCCCHHHCCCCEEEEEEEEECCCCCCCCCCEECCC
NSIYLYQVPSNRLADVTEALFELYEKNKDISEDPSLVFRLLGNKKIIEWLKGHEKTKDLM
CCEEEEECCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCHHHHHHHHCCHHHHHHH
KPHKFDRKIEGYREYHDLLRKRLEEVSRYG
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKIPIEPNFRTDPKDYSEEERAKLKTKGLTEDTIGIYSSFHDLSREDLEKEVSLIAKSFG
CCCCCCCCCCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHCC
IYIEFNRDKMKLNGVKDWIYMVRLPIPGGGPISSKQWRILDDISNKYTISDAYTGYPSPS
EEEEECCCEEEECCCEEEEEEEEEECCCCCCCCCCCEEEHHCCCCCEEECCCCCCCCCCC
LKLTTRQAIQFHHVKKRDLPNLIREVAESGFLTVNGCGDNVRNTIACPLSKYWVFDANSL
EEEEHHHHHHHHHHHHCCHHHHHHHHHHCCCEEEECCCCCCCCEEECCCCEEEEECCHHH
ARKIANYFRLPLDLYLQVFEIPLIENRQFDRESFKYGENLLPRKFKIAIAGVLRTINGKY
HHHHHHHHCCCHHHHHHHHHCCCCCCCCCCHHHHHHCCCCCCCHHHHHHHHHHHHCCCCE
IIDNCVEVQSNDIGIVPLIEDEKVIGYQIYVGGSMGENNSYPTFSALGLPIGTVVNDSEL
EEECEEEECCCCEEEEEEECCCEEEEEEEEECCCCCCCCCCCCCCCCCCCCCEEECHHHH
IKVLDAIVTIQEEWGDRKNRHWARFKYVVYKMGLEWLREKVREHSGIQLGKIVKVDLTHK
HHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEECCEEEEEECCC
DLHLGWINLGDNKWAYGIFVENGRLIDGKNGRTKSMIRYIADNFDNLMFYITPNQHLLIT
EEEEEEEEECCCCEEEEEEEECCEEEECCCCCHHHHHHHHHCCCCCEEEEECCCCEEEEE
EIDQPQKEKIDGILREFNYGFRDGKPYSSLRINSTACVGFPTCKLSFTDSERFLPSLIDE
ECCCCHHHHHHHHHHHHCCCCCCCCCCCEEEECCEEEEECCEEEEEECCCHHHHHHHHHH
LERRGWKDIPVSIGLSGCVAQCSRPALHPISWVGSGYELYMLKIGGGNGSLGEPLIDWDE
HHHCCCCCCCEECCCHHHHHHCCCCCCCCHHHCCCCEEEEEEEEECCCCCCCCCCEECCC
NSIYLYQVPSNRLADVTEALFELYEKNKDISEDPSLVFRLLGNKKIIEWLKGHEKTKDLM
CCEEEEECCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCHHHHHHHHCCHHHHHHH
KPHKFDRKIEGYREYHDLLRKRLEEVSRYG
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA