Click here to switch to the map view.

The map label for this gene is adh-13 [C]

Identifier: 15899588

GI number: 15899588

Start: 2630800

End: 2631732

Strand: Reverse

Name: adh-13 [C]

Synonym: SSO2878

Alternate gene names: 15899588

Gene position: 2631732-2630800 (Counterclockwise)

Preceding gene: 15899589

Following gene: 15899587

Centisome position: 87.95

GC content: 38.37

Gene sequence:

>933_bases
ATGAAAGCGGCTATTTTAACACAGTTTAACTCACCCTTTATAATAGGTAACGCAGAGCCTCATGGAGTAGGAGTTAGAAT
AAACGTAGCGTATACTGGAATATGTGGAAGGGATCTAGTTATATGGAAGGGTGGATTTAAAAATCTCAAGCTACCCTTAA
TCCTAGGGCATGAAATAGTAGGTTACTATAATGGAAGACCAGTAGCTGTTTACCCAAATCTATATTGCGGAAGCTGTGAC
TATTGTAAAAGCGGGAAGGAGAATTTATGTGATAACGCTAGAATTTTAGGAGAGGGAGAGATAACTGGAGGATATGCAGA
GCAGGTCATTGTCCCAGAAAGAAATCTCATACCCTTGCCAGACGATAAACTCGAAAAATACGCAGCTACAATGGACCCAG
TTGCCACTGCAATTCACGCATCTAAACTTGCAGATTTAAAGAAGGATAGTAAAGTTTTGGTAACTGGGGCAGGTGGAGGA
GTAGGTATCCATCTTGTACAATACTTGAAATATTTAGGTATATCAAACGTTTATGGGTTATCATCTAAAGGAGAAAAGCT
TAAAGAATTGGGGGTAACGCCAGTGAGTGATATAAGAGGTGAAAAGTTTGATGCAATATTTGAACTAGTGGGTTCTAAAA
CCATAAACGATTCGTTAAGGGCATTAAAGAAGGAAGGTATTCTAGTTTTGATCGGAAATACTGAAGGGGAGCCGATAACG
CTATCAAGGCCAGCAATGAGCATAATGAGACAGCATAAAATAGTAGGTTCTGCATCTTATACTCAAGCAGAATACGAGGA
AGCCATTAAATTGGTAGGGTATGGGAAAATCAAAGCTATATACGAAATTTATGAATTAGAGAGAATAAATGAGGCATATA
GGAAAATGTTGGAGAGAAAGGTCTTAGGAAGAGCTATTTTAAAGGTAATCTGA

Upstream 100 bases:

>100_bases
GACGACGCGTTGGCTGGAAAGATTGAAGATAAGTGTATGTTTGTACCTAAATCTTTAAGTCAACAATGAATATATTAACA
ATCAATTCCTTTTTTAATAT

Downstream 100 bases:

>100_bases
CCTTCTTTCTACATGTTGTTCTTATAAGGTGATCACCTAAATATTATCTTTTCACATAGTTTTTTCTTTATTCACTTATG
ATTAATATATTACTTTTCGG

Product: zinc-containing alcohol dehydrogenase

Products: NA

Alternate protein names: Acryloyl-CoA reductase [H]

Number of amino acids: Translated: 310; Mature: 310

Protein sequence:

>310_residues
MKAAILTQFNSPFIIGNAEPHGVGVRINVAYTGICGRDLVIWKGGFKNLKLPLILGHEIVGYYNGRPVAVYPNLYCGSCD
YCKSGKENLCDNARILGEGEITGGYAEQVIVPERNLIPLPDDKLEKYAATMDPVATAIHASKLADLKKDSKVLVTGAGGG
VGIHLVQYLKYLGISNVYGLSSKGEKLKELGVTPVSDIRGEKFDAIFELVGSKTINDSLRALKKEGILVLIGNTEGEPIT
LSRPAMSIMRQHKIVGSASYTQAEYEEAIKLVGYGKIKAIYEIYELERINEAYRKMLERKVLGRAILKVI

Sequences:

>Translated_310_residues
MKAAILTQFNSPFIIGNAEPHGVGVRINVAYTGICGRDLVIWKGGFKNLKLPLILGHEIVGYYNGRPVAVYPNLYCGSCD
YCKSGKENLCDNARILGEGEITGGYAEQVIVPERNLIPLPDDKLEKYAATMDPVATAIHASKLADLKKDSKVLVTGAGGG
VGIHLVQYLKYLGISNVYGLSSKGEKLKELGVTPVSDIRGEKFDAIFELVGSKTINDSLRALKKEGILVLIGNTEGEPIT
LSRPAMSIMRQHKIVGSASYTQAEYEEAIKLVGYGKIKAIYEIYELERINEAYRKMLERKVLGRAILKVI
>Mature_310_residues
MKAAILTQFNSPFIIGNAEPHGVGVRINVAYTGICGRDLVIWKGGFKNLKLPLILGHEIVGYYNGRPVAVYPNLYCGSCD
YCKSGKENLCDNARILGEGEITGGYAEQVIVPERNLIPLPDDKLEKYAATMDPVATAIHASKLADLKKDSKVLVTGAGGG
VGIHLVQYLKYLGISNVYGLSSKGEKLKELGVTPVSDIRGEKFDAIFELVGSKTINDSLRALKKEGILVLIGNTEGEPIT
LSRPAMSIMRQHKIVGSASYTQAEYEEAIKLVGYGKIKAIYEIYELERINEAYRKMLERKVLGRAILKVI

Specific function: Plays a role in autotrophic carbon fixation via the 3- hydroxypropionate/4-hydroxybutyrate cycle. Catalyzes the acryloyl- CoA dependent NADPH oxidation and formation of propionyl-CoA [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the zinc-containing alcohol dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1790718, Length=306, Percent_Identity=27.7777777777778, Blast_Score=103, Evalue=1e-23,
Organism=Escherichia coli, GI226510992, Length=299, Percent_Identity=27.0903010033445, Blast_Score=103, Evalue=1e-23,
Organism=Escherichia coli, GI1787863, Length=208, Percent_Identity=32.2115384615385, Blast_Score=92, Evalue=6e-20,
Organism=Escherichia coli, GI1788073, Length=320, Percent_Identity=26.25, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI1788407, Length=325, Percent_Identity=26.1538461538462, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI1786518, Length=333, Percent_Identity=27.027027027027, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI1790045, Length=202, Percent_Identity=28.2178217821782, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI87081918, Length=342, Percent_Identity=26.3157894736842, Blast_Score=68, Evalue=6e-13,
Organism=Escherichia coli, GI87082401, Length=311, Percent_Identity=26.0450160771704, Blast_Score=62, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI17562876, Length=319, Percent_Identity=25.705329153605, Blast_Score=91, Evalue=9e-19,
Organism=Caenorhabditis elegans, GI71988145, Length=324, Percent_Identity=25.3086419753086, Blast_Score=88, Evalue=7e-18,
Organism=Caenorhabditis elegans, GI17562584, Length=337, Percent_Identity=26.4094955489614, Blast_Score=79, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17562878, Length=204, Percent_Identity=28.4313725490196, Blast_Score=79, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI17562582, Length=338, Percent_Identity=25.7396449704142, Blast_Score=78, Evalue=7e-15,
Organism=Saccharomyces cerevisiae, GI6319258, Length=336, Percent_Identity=28.5714285714286, Blast_Score=107, Evalue=3e-24,
Organism=Saccharomyces cerevisiae, GI6324486, Length=311, Percent_Identity=27.6527331189711, Blast_Score=88, Evalue=2e-18,
Organism=Saccharomyces cerevisiae, GI6322619, Length=317, Percent_Identity=26.1829652996845, Blast_Score=87, Evalue=5e-18,
Organism=Saccharomyces cerevisiae, GI6323961, Length=311, Percent_Identity=27.3311897106109, Blast_Score=86, Evalue=6e-18,
Organism=Saccharomyces cerevisiae, GI6319955, Length=317, Percent_Identity=26.1829652996845, Blast_Score=86, Evalue=9e-18,
Organism=Saccharomyces cerevisiae, GI6323729, Length=320, Percent_Identity=27.8125, Blast_Score=82, Evalue=1e-16,
Organism=Saccharomyces cerevisiae, GI6319621, Length=323, Percent_Identity=26.9349845201238, Blast_Score=80, Evalue=6e-16,
Organism=Saccharomyces cerevisiae, GI6319257, Length=320, Percent_Identity=25, Blast_Score=77, Evalue=4e-15,
Organism=Drosophila melanogaster, GI17137530, Length=178, Percent_Identity=30.3370786516854, Blast_Score=67, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR002085
- InterPro:   IPR002328
- InterPro:   IPR011032
- InterPro:   IPR016040
- InterPro:   IPR002364 [H]

Pfam domain/function: PF08240 ADH_N; PF00107 ADH_zinc_N [H]

EC number: =1.3.1.84 [H]

Molecular weight: Translated: 33877; Mature: 33877

Theoretical pI: Translated: 8.97; Mature: 8.97

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKAAILTQFNSPFIIGNAEPHGVGVRINVAYTGICGRDLVIWKGGFKNLKLPLILGHEIV
CCCEEEEECCCCEEEECCCCCCEEEEEEEEEECCCCCEEEEEECCCCCCEEEEEECCEEE
GYYNGRPVAVYPNLYCGSCDYCKSGKENLCDNARILGEGEITGGYAEQVIVPERNLIPLP
EEECCEEEEECCCCEECCCHHHCCCCCCCCCCCEEEECCCCCCCCCCEEECCCCCCCCCC
DDKLEKYAATMDPVATAIHASKLADLKKDSKVLVTGAGGGVGIHLVQYLKYLGISNVYGL
CHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHHCCCCCCCC
SSKGEKLKELGVTPVSDIRGEKFDAIFELVGSKTINDSLRALKKEGILVLIGNTEGEPIT
CCCCHHHHHCCCCCHHHHCCCHHHHHHHHHCCCCHHHHHHHHHHCCEEEEEECCCCCCEE
LSRPAMSIMRQHKIVGSASYTQAEYEEAIKLVGYGKIKAIYEIYELERINEAYRKMLERK
ECHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHH
VLGRAILKVI
HHHHHHHHHC
>Mature Secondary Structure
MKAAILTQFNSPFIIGNAEPHGVGVRINVAYTGICGRDLVIWKGGFKNLKLPLILGHEIV
CCCEEEEECCCCEEEECCCCCCEEEEEEEEEECCCCCEEEEEECCCCCCEEEEEECCEEE
GYYNGRPVAVYPNLYCGSCDYCKSGKENLCDNARILGEGEITGGYAEQVIVPERNLIPLP
EEECCEEEEECCCCEECCCHHHCCCCCCCCCCCEEEECCCCCCCCCCEEECCCCCCCCCC
DDKLEKYAATMDPVATAIHASKLADLKKDSKVLVTGAGGGVGIHLVQYLKYLGISNVYGL
CHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHHCCCCCCCC
SSKGEKLKELGVTPVSDIRGEKFDAIFELVGSKTINDSLRALKKEGILVLIGNTEGEPIT
CCCCHHHHHCCCCCHHHHCCCHHHHHHHHHCCCCHHHHHHHHHHCCEEEEEECCCCCCEE
LSRPAMSIMRQHKIVGSASYTQAEYEEAIKLVGYGKIKAIYEIYELERINEAYRKMLERK
ECHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHH
VLGRAILKVI
HHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA