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The map label for this gene is dgoD [H]

Identifier: 15899388

GI number: 15899388

Start: 2421630

End: 2422811

Strand: Reverse

Name: dgoD [H]

Synonym: SSO2665

Alternate gene names: 15899388

Gene position: 2422811-2421630 (Counterclockwise)

Preceding gene: 15899391

Following gene: 15899386

Centisome position: 80.97

GC content: 38.41

Gene sequence:

>1182_bases
ATGACAAAGATTTCAGAAATCGAAGCGTACATTTTAGGTAAGGAAGTAACAAGCGCTCAATGGGCTTCATTAATGGTACT
GGTAAGGGTAACCACAAACGATGGTAGAGTAGGCTGGGGAGAAACTGTAAGTGCCTTAAGGGCAGAAGCTGTGGCAAATT
TTGTAAAAAAGATAAATACTGTATTAAAAGGAAATGACGTGTTTAACGTTGAAAAGAACAGGCTAGAATGGTATAAACAT
GATTTCAATATGACTATCTCCTTAGAGTCTACAACAGCCTATAGTGCAGTAGATATAGCTTCTTGGGACATAATCGGAAA
AGAGTTAGGTGCTCCATTATATAAGCTGCTTGGAGGAAAAACAAGAGATAAAGTACTTGTCTACGCTAATGGTTGGTATC
AAAACTGCGTGAAGCCAGAGGACTTTGCGGAAAAAGCTAAGGAGATCGTAAAAATGGGATATAAGGCTTTGAAATTTGAC
CCATTTGGTCCGTACTTTAACGATATTTCAAAGAAAGGACTAGATATAGCTGAGGAGAGAGTAAAGGCTGTTAGAGAGGC
AGTTGGAGACAACGTGGATATTTTAATAGAGCATCACGGTAGGTTTAATGCGAATTCGGCTATTATGATAGCGAAAAGAC
TAGAGAAGTATAATCCATTGTTCATGGAAGAACCAATTCATCCTGAGGATGTGGAAGGACTTAGAAAATATAGGAACAAT
ACGAGCTTAAGGATTGCGTTAGGTGAAAGGATAATTAATAAACAGCAAGCCTTATACTTTATGAAAGAGGGATTAGTGGA
TTTCTTACAAGCTGATCTATACAGAATTGGTGGAGTTACTGAGACCAAGAAGGTAGTAGGGATTGCTGAGACCTTTGACG
TACAGATGGCTTTTCACAATGCTCAAGGTCCAATACTAAACGCCGTAACACTACAGTTTGACGCATTTATACCAAACTTC
TTAATACAAGAGTCTTTCTATGATTGGTTCCCGAGTTGGAAGAGGGAGCTAATATATAATGGTACTCCAATAGATAACGG
ATACGCTATAATACCGGAAAGACCGGGTTTAGGAGTTGAAGTAAATGAGAAAATGTTAGATAGTTTAAAGGTTAAAGGTG
AGGAGTACTTTAATCCAGAAGAACCAGTGTGGGTAGTTAAAGGAACTTGGAGAGACTATTAG

Upstream 100 bases:

>100_bases
TTGTAATTGAGATTGCTAAAATTGTCCTCCTTCTCATACAGTATATACCCTATTGTGTAGCCGATAAAAACTTTATTTTT
CCAAACCTTTACTTACATAC

Downstream 100 bases:

>100_bases
TTATATCTCGCCCTTGGTAATTTCTTCTGGATCCGGTTTTCTGCTTATTATTCTACCTCCATCAATTATAATTTCCGTTC
CGGTGATGAAGCTATTCAAA

Product: muconate cycloisomerase related protein

Products: NA

Alternate protein names: GalD [H]

Number of amino acids: Translated: 393; Mature: 392

Protein sequence:

>393_residues
MTKISEIEAYILGKEVTSAQWASLMVLVRVTTNDGRVGWGETVSALRAEAVANFVKKINTVLKGNDVFNVEKNRLEWYKH
DFNMTISLESTTAYSAVDIASWDIIGKELGAPLYKLLGGKTRDKVLVYANGWYQNCVKPEDFAEKAKEIVKMGYKALKFD
PFGPYFNDISKKGLDIAEERVKAVREAVGDNVDILIEHHGRFNANSAIMIAKRLEKYNPLFMEEPIHPEDVEGLRKYRNN
TSLRIALGERIINKQQALYFMKEGLVDFLQADLYRIGGVTETKKVVGIAETFDVQMAFHNAQGPILNAVTLQFDAFIPNF
LIQESFYDWFPSWKRELIYNGTPIDNGYAIIPERPGLGVEVNEKMLDSLKVKGEEYFNPEEPVWVVKGTWRDY

Sequences:

>Translated_393_residues
MTKISEIEAYILGKEVTSAQWASLMVLVRVTTNDGRVGWGETVSALRAEAVANFVKKINTVLKGNDVFNVEKNRLEWYKH
DFNMTISLESTTAYSAVDIASWDIIGKELGAPLYKLLGGKTRDKVLVYANGWYQNCVKPEDFAEKAKEIVKMGYKALKFD
PFGPYFNDISKKGLDIAEERVKAVREAVGDNVDILIEHHGRFNANSAIMIAKRLEKYNPLFMEEPIHPEDVEGLRKYRNN
TSLRIALGERIINKQQALYFMKEGLVDFLQADLYRIGGVTETKKVVGIAETFDVQMAFHNAQGPILNAVTLQFDAFIPNF
LIQESFYDWFPSWKRELIYNGTPIDNGYAIIPERPGLGVEVNEKMLDSLKVKGEEYFNPEEPVWVVKGTWRDY
>Mature_392_residues
TKISEIEAYILGKEVTSAQWASLMVLVRVTTNDGRVGWGETVSALRAEAVANFVKKINTVLKGNDVFNVEKNRLEWYKHD
FNMTISLESTTAYSAVDIASWDIIGKELGAPLYKLLGGKTRDKVLVYANGWYQNCVKPEDFAEKAKEIVKMGYKALKFDP
FGPYFNDISKKGLDIAEERVKAVREAVGDNVDILIEHHGRFNANSAIMIAKRLEKYNPLFMEEPIHPEDVEGLRKYRNNT
SLRIALGERIINKQQALYFMKEGLVDFLQADLYRIGGVTETKKVVGIAETFDVQMAFHNAQGPILNAVTLQFDAFIPNFL
IQESFYDWFPSWKRELIYNGTPIDNGYAIIPERPGLGVEVNEKMLDSLKVKGEEYFNPEEPVWVVKGTWRDY

Specific function: Catalyzes the dehydration of D-galactonate to 2-keto-3- deoxy-D-galactonate [H]

COG id: COG4948

COG function: function code MR; L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mandelate racemase/muconate lactonizing enzyme family. GalD subfamily [H]

Homologues:

Organism=Homo sapiens, GI42544119, Length=329, Percent_Identity=22.7963525835866, Blast_Score=69, Evalue=9e-12,
Organism=Homo sapiens, GI186972148, Length=329, Percent_Identity=22.7963525835866, Blast_Score=68, Evalue=1e-11,
Organism=Escherichia coli, GI48994953, Length=370, Percent_Identity=29.4594594594595, Blast_Score=164, Evalue=9e-42,
Organism=Escherichia coli, GI1787864, Length=369, Percent_Identity=27.9132791327913, Blast_Score=140, Evalue=2e-34,
Organism=Escherichia coli, GI226510960, Length=351, Percent_Identity=24.7863247863248, Blast_Score=86, Evalue=5e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018110
- InterPro:   IPR013342
- InterPro:   IPR013341
- InterPro:   IPR001354 [H]

Pfam domain/function: PF01188 MR_MLE; PF02746 MR_MLE_N [H]

EC number: =4.2.1.6 [H]

Molecular weight: Translated: 44762; Mature: 44631

Theoretical pI: Translated: 5.58; Mature: 5.58

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKISEIEAYILGKEVTSAQWASLMVLVRVTTNDGRVGWGETVSALRAEAVANFVKKINT
CCCHHHHHHEEECCHHHHHHHEEEEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHH
VLKGNDVFNVEKNRLEWYKHDFNMTISLESTTAYSAVDIASWDIIGKELGAPLYKLLGGK
HHCCCCEEECCHHHHHHEEECCCEEEEEECCCCCCEEEHHHHHHHHHHHCCHHHHHHCCC
TRDKVLVYANGWYQNCVKPEDFAEKAKEIVKMGYKALKFDPFGPYFNDISKKGLDIAEER
CCCEEEEEECCHHHCCCCHHHHHHHHHHHHHCCCHHEECCCCCCHHHHHHHCCCHHHHHH
VKAVREAVGDNVDILIEHHGRFNANSAIMIAKRLEKYNPLFMEEPIHPEDVEGLRKYRNN
HHHHHHHHCCCEEEEEEECCCCCCCCHHHHHHHHHHCCCCEECCCCCCCHHHHHHHHCCC
TSLRIALGERIINKQQALYFMKEGLVDFLQADLYRIGGVTETKKVVGIAETFDVQMAFHN
CEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHEEEHHHEEEEEEEEC
AQGPILNAVTLQFDAFIPNFLIQESFYDWFPSWKRELIYNGTPIDNGYAIIPERPGLGVE
CCCCEEEEEEEEEHHHCHHHHHHHHHHHHCHHHHHHHEECCCCCCCCEEEEECCCCCCCE
VNEKMLDSLKVKGEEYFNPEEPVWVVKGTWRDY
ECHHHHHHHHCCCCCCCCCCCCEEEEECCCCCC
>Mature Secondary Structure 
TKISEIEAYILGKEVTSAQWASLMVLVRVTTNDGRVGWGETVSALRAEAVANFVKKINT
CCHHHHHHEEECCHHHHHHHEEEEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHH
VLKGNDVFNVEKNRLEWYKHDFNMTISLESTTAYSAVDIASWDIIGKELGAPLYKLLGGK
HHCCCCEEECCHHHHHHEEECCCEEEEEECCCCCCEEEHHHHHHHHHHHCCHHHHHHCCC
TRDKVLVYANGWYQNCVKPEDFAEKAKEIVKMGYKALKFDPFGPYFNDISKKGLDIAEER
CCCEEEEEECCHHHCCCCHHHHHHHHHHHHHCCCHHEECCCCCCHHHHHHHCCCHHHHHH
VKAVREAVGDNVDILIEHHGRFNANSAIMIAKRLEKYNPLFMEEPIHPEDVEGLRKYRNN
HHHHHHHHCCCEEEEEEECCCCCCCCHHHHHHHHHHCCCCEECCCCCCCHHHHHHHHCCC
TSLRIALGERIINKQQALYFMKEGLVDFLQADLYRIGGVTETKKVVGIAETFDVQMAFHN
CEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHEEEHHHEEEEEEEEC
AQGPILNAVTLQFDAFIPNFLIQESFYDWFPSWKRELIYNGTPIDNGYAIIPERPGLGVE
CCCCEEEEEEEEEHHHCHHHHHHHHHHHHCHHHHHHHEECCCCCCCCEEEEECCCCCCCE
VNEKMLDSLKVKGEEYFNPEEPVWVVKGTWRDY
ECHHHHHHHHCCCCCCCCCCCCEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA