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The map label for this gene is prpD1 [H]

Identifier: 15899315

GI number: 15899315

Start: 2354060

End: 2355367

Strand: Direct

Name: prpD1 [H]

Synonym: SSO2586

Alternate gene names: 15899315

Gene position: 2354060-2355367 (Clockwise)

Preceding gene: 15899310

Following gene: 15899316

Centisome position: 78.67

GC content: 36.85

Gene sequence:

>1308_bases
ATGGAAATAGCTGAAAAGATTGCTGAATTTGTGAGTTCAGTAAATTATCAAAATTTAAGTGAAAAGGTTATACATGAGGC
AAAAAGAAGAATAATTGATGCAATAGCAGTAGCTCGTGGAGCATTAAATTCCCCACCTCATTTAGTTAACAAAAACGTGG
TAACATACTTTCTGGGTTCTGTACCTCTACTTTTTGGAGGAAATGCAACTCCAGATTTCGCAGCATTTTACAATACTTTC
TTAATTAGATATCTCGATTTTAATGATACTTACCTTTCAAAGGAGCCCCTACATCCTAGTGACATGATAGGGGCTTTCTT
ATCCTTAGGTTCCCTATTTAATTTAGAAGGGAAGGATGTAATAGAAGCTGTTGCTATAGGATATGAGGTCGGTGTAAAGT
TATGCGACGCAACATCATTGAGAAAGAAAGGTTTTGATCACGTGACTTTCCTTCAAGTTGGAGCTGCAGCAGGTTTAGCT
AAGATGTTAAAATTGGACGAAAAATCTACTGTTAACGCTATTTCATTAACATTAGTACCAAATATTGCACTTAGAGAGAC
TAGATCTGGGGAATTATCGATGTGGAAGGCTGGTGCAGCAGCAGATGCCTCAAGGAAAGCGGTTTTTGGAGCGCTATTAG
CTAAATTTGGAATGACGAGCCCTTCAAAGCCTTTCTCAGGTAGATTAGGTTTTGTAAACGTTGTGGCAAAAGATTTTGAC
TCTACGGTGTTTAATCGCCTAGAGGACGATGGTATACTTAAAACCAGCTTAAAGAAATATCCAGTGGAGTATCATGCTGA
GGCAGTGGTAGAAGCTGGGAAGAGTTTTAACGTTAACGTTGATGATATAATTAAGATAGAAGTCGAAACCTATGAAGCAG
CTAAGACAATAATAGCAGATGAGGAGAAATGGAATCCTACCAATAAGGAGACAGCAGATCATAGTCTGCCCTACATCCTG
GCTTATACCTTAATTAAGAAGGATTTCTGGCTTGACGCATACGATAAAGAGATGATATTTAATGAAAAAATAAGAAATTT
AATGAAAAAGATTACTGTTATTGAGGATGAAAAATATACTAGTATATATCCGAAGGAGCTACCCGTTAAGGTCACAATCT
ATACCACTAAGGGTAAAGATACGATCGAAGTTAGGAACCCTAGAGGATATTATAATAATCCAATGACTGATGCTGAAGTT
GAAGAAAAATACTTAAGGCTGAAAGGTAGAAAGGAAGAGTTAAATATTTTGTGGAATATGGAAGAATTAAAGGTGAAGGA
GATTGTCTCAAGTATTAAGGGAAGCTGA

Upstream 100 bases:

>100_bases
CATATTATCACGAGTATAAATATGCATTCTAAAGTATATTAAGCTTTTTTCAATGTTCATTATAGTTCGACTTTTATACT
CCCTTTAATTTTACTCTATT

Downstream 100 bases:

>100_bases
TTTCTTAATGGTTCCGGGAGTTTTTAATCCTTTTACTGCAATTCTGGCAAAAAAGGTAGGTTTTAAGGCTGTATACTTAT
CAGGTGCTGCTCTTACATCA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 435; Mature: 435

Protein sequence:

>435_residues
MEIAEKIAEFVSSVNYQNLSEKVIHEAKRRIIDAIAVARGALNSPPHLVNKNVVTYFLGSVPLLFGGNATPDFAAFYNTF
LIRYLDFNDTYLSKEPLHPSDMIGAFLSLGSLFNLEGKDVIEAVAIGYEVGVKLCDATSLRKKGFDHVTFLQVGAAAGLA
KMLKLDEKSTVNAISLTLVPNIALRETRSGELSMWKAGAAADASRKAVFGALLAKFGMTSPSKPFSGRLGFVNVVAKDFD
STVFNRLEDDGILKTSLKKYPVEYHAEAVVEAGKSFNVNVDDIIKIEVETYEAAKTIIADEEKWNPTNKETADHSLPYIL
AYTLIKKDFWLDAYDKEMIFNEKIRNLMKKITVIEDEKYTSIYPKELPVKVTIYTTKGKDTIEVRNPRGYYNNPMTDAEV
EEKYLRLKGRKEELNILWNMEELKVKEIVSSIKGS

Sequences:

>Translated_435_residues
MEIAEKIAEFVSSVNYQNLSEKVIHEAKRRIIDAIAVARGALNSPPHLVNKNVVTYFLGSVPLLFGGNATPDFAAFYNTF
LIRYLDFNDTYLSKEPLHPSDMIGAFLSLGSLFNLEGKDVIEAVAIGYEVGVKLCDATSLRKKGFDHVTFLQVGAAAGLA
KMLKLDEKSTVNAISLTLVPNIALRETRSGELSMWKAGAAADASRKAVFGALLAKFGMTSPSKPFSGRLGFVNVVAKDFD
STVFNRLEDDGILKTSLKKYPVEYHAEAVVEAGKSFNVNVDDIIKIEVETYEAAKTIIADEEKWNPTNKETADHSLPYIL
AYTLIKKDFWLDAYDKEMIFNEKIRNLMKKITVIEDEKYTSIYPKELPVKVTIYTTKGKDTIEVRNPRGYYNNPMTDAEV
EEKYLRLKGRKEELNILWNMEELKVKEIVSSIKGS
>Mature_435_residues
MEIAEKIAEFVSSVNYQNLSEKVIHEAKRRIIDAIAVARGALNSPPHLVNKNVVTYFLGSVPLLFGGNATPDFAAFYNTF
LIRYLDFNDTYLSKEPLHPSDMIGAFLSLGSLFNLEGKDVIEAVAIGYEVGVKLCDATSLRKKGFDHVTFLQVGAAAGLA
KMLKLDEKSTVNAISLTLVPNIALRETRSGELSMWKAGAAADASRKAVFGALLAKFGMTSPSKPFSGRLGFVNVVAKDFD
STVFNRLEDDGILKTSLKKYPVEYHAEAVVEAGKSFNVNVDDIIKIEVETYEAAKTIIADEEKWNPTNKETADHSLPYIL
AYTLIKKDFWLDAYDKEMIFNEKIRNLMKKITVIEDEKYTSIYPKELPVKVTIYTTKGKDTIEVRNPRGYYNNPMTDAEV
EEKYLRLKGRKEELNILWNMEELKVKEIVSSIKGS

Specific function: Catalyzes the dehydration of 2-methylcitrate to 2- methyl-cis-aconitate [H]

COG id: COG2079

COG function: function code R; Uncharacterized protein involved in propionate catabolism

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the prpD family [H]

Homologues:

Organism=Escherichia coli, GI1786528, Length=317, Percent_Identity=31.2302839116719, Blast_Score=123, Evalue=3e-29,
Organism=Saccharomyces cerevisiae, GI6325258, Length=327, Percent_Identity=32.4159021406728, Blast_Score=117, Evalue=3e-27,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005656 [H]

Pfam domain/function: PF03972 MmgE_PrpD [H]

EC number: =4.2.1.79 [H]

Molecular weight: Translated: 48672; Mature: 48672

Theoretical pI: Translated: 6.55; Mature: 6.55

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEIAEKIAEFVSSVNYQNLSEKVIHEAKRRIIDAIAVARGALNSPPHLVNKNVVTYFLGS
CCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHCCCHHHHHHCC
VPLLFGGNATPDFAAFYNTFLIRYLDFNDTYLSKEPLHPSDMIGAFLSLGSLFNLEGKDV
CCEEECCCCCCHHHHHHHHHHHHEECCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCHHH
IEAVAIGYEVGVKLCDATSLRKKGFDHVTFLQVGAAAGLAKMLKLDEKSTVNAISLTLVP
HHHHHHHHHHHHEEECCHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEEC
NIALRETRSGELSMWKAGAAADASRKAVFGALLAKFGMTSPSKPFSGRLGFVNVVAKDFD
CHHEECCCCCCEEEEECCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHH
STVFNRLEDDGILKTSLKKYPVEYHAEAVVEAGKSFNVNVDDIIKIEVETYEAAKTIIAD
HHHHHHHCCCCHHHHHHHHCCHHHHHHHHHHCCCCCCCCCCCEEEEEEEHHHHHHHHHCC
EEKWNPTNKETADHSLPYILAYTLIKKDFWLDAYDKEMIFNEKIRNLMKKITVIEDEKYT
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHEEECCCCCC
SIYPKELPVKVTIYTTKGKDTIEVRNPRGYYNNPMTDAEVEEKYLRLKGRKEELNILWNM
CCCCCCCCEEEEEEEECCCCEEEEECCCCCCCCCCCCHHHHHHHHHHCCCCCCEEEEECH
EELKVKEIVSSIKGS
HHHHHHHHHHHHCCC
>Mature Secondary Structure
MEIAEKIAEFVSSVNYQNLSEKVIHEAKRRIIDAIAVARGALNSPPHLVNKNVVTYFLGS
CCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHCCCHHHHHHCC
VPLLFGGNATPDFAAFYNTFLIRYLDFNDTYLSKEPLHPSDMIGAFLSLGSLFNLEGKDV
CCEEECCCCCCHHHHHHHHHHHHEECCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCHHH
IEAVAIGYEVGVKLCDATSLRKKGFDHVTFLQVGAAAGLAKMLKLDEKSTVNAISLTLVP
HHHHHHHHHHHHEEECCHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEEC
NIALRETRSGELSMWKAGAAADASRKAVFGALLAKFGMTSPSKPFSGRLGFVNVVAKDFD
CHHEECCCCCCEEEEECCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHH
STVFNRLEDDGILKTSLKKYPVEYHAEAVVEAGKSFNVNVDDIIKIEVETYEAAKTIIAD
HHHHHHHCCCCHHHHHHHHCCHHHHHHHHHHCCCCCCCCCCCEEEEEEEHHHHHHHHHCC
EEKWNPTNKETADHSLPYILAYTLIKKDFWLDAYDKEMIFNEKIRNLMKKITVIEDEKYT
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHEEECCCCCC
SIYPKELPVKVTIYTTKGKDTIEVRNPRGYYNNPMTDAEVEEKYLRLKGRKEELNILWNM
CCCCCCCCEEEEEEEECCCCEEEEECCCCCCCCCCCCHHHHHHHHHHCCCCCCEEEEECH
EELKVKEIVSSIKGS
HHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11976302; 12948626 [H]