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The map label for this gene is glnA-2 [H]

Identifier: 15899188

GI number: 15899188

Start: 2215993

End: 2217270

Strand: Direct

Name: glnA-2 [H]

Synonym: SSO2440

Alternate gene names: 15899188

Gene position: 2215993-2217270 (Clockwise)

Preceding gene: 15899187

Following gene: 15899189

Centisome position: 74.06

GC content: 34.27

Gene sequence:

>1278_bases
GTGTCTAAAGAGAATATATTTGATGCTTTAAAATCTGGAAAAATAGATTATGTGAGAGTAGAATTTGTAGATATATTAGG
GAATACTAAGGGTAGGTCTCTTAGAAGGGCAGAATTCGAAAATGTAATAAATGACAATAAGGGAGTTGATTATCCAGAAT
CCTTAGCATTAATGGATTACAAAGATAGACCGATAAAATCAAGGTATGAGGATATTATTGCTATACCCGATCTGAACACC
TTTGTTGCAATACCGTATTTAGAAAGAACTGCTAGGGTACTCTCATTTTTGGCTCAACCTGATGGTTTACCGTATCCATA
TTGTAGTAGATCTATACTAAATAAGGCAATAGAGAAGTTAAAAGAAGCTGGTTATACGCTACAAGTTTCATTTGAACCGA
CATTTTATCTCTTGAATTCTGCTCTTAATCCAGCAGACTATTCTAAAGCTTTCTCGTTAGAAGGATTATTGGAACAGCAG
AACTTCCTTAAATTGCTTATAAAATATTTAGAAGAAATCGATATAAAAGTTGAAACTATTAATAAACACTATGGTCCGGG
TCAATACGAGGTTAAGCTTTCGCAAAAACCCGTTTTAGAGGCTGCAGATTCCCTAATTTCCAGTAGGGAAGTGATTAGGG
ATACTGCCAAAATGAATAATGTGATTGCTACTTTTATGCCTAAACCATTTAAAGATTACCCAAGTAGCAGTATGGATATC
ACATTAAGTCTGCAAACAGTAGACGGAAAGGACATCATGTACGATCCTAATGACTCTAAGGGAATTGGGCTTAGTAAGAT
TGCATATAATTTCATTTCTGGAATATTAGAGCACCTTCCTTCAATATTATCTATCGCTGCACCAACTGTTAATTCATATA
AGAGATTTAAGGAAGTAGTAACTCCAAACATGCCGGGAATAGGCTCTGAAAGGCACTACATAGTGAGATTACCAAGTTAT
TATAAGGATACTCATCAAGTAGAGTTCAGATTAGCAGATCCACTGGCGAATCCGTACATTCTGTTAGCCAGTATGATATA
TGCAGGTTTAGATGGTATAGAAAGAAATCTTATGGCTAATGTAAATGAGTATTATGGCACATTGCCACAAACCCTTAAGG
AATCTTTAAGTAGATTGGAAAATGATACATATATGAAGTATAATTTAGGTCAAGATTTGATTTCCATCTACATTAATATT
AAAAATATAGAGATAGAAGAATACGAATCACAAATAACTGAATGGGAAAGAGACTACTATCTAAAGGCAGGATGGTAA

Upstream 100 bases:

>100_bases
GGGCTGAGGGTTAATATTAAATACGTGAAATCCTATGATGCCCAGAACTATTTGTGTTAACATTTATTAAATTATTCTAC
AAATAGTTGATGAGATAAAA

Downstream 100 bases:

>100_bases
ATGCTAGGTGCTATTCTGAAAAATTTCGGTGAGGAGCTAAGTCTTGAAGACGTAAGAGAACCTTCTAACGGAATTGTTCT
AAAAGTTCTAGCCACTGGAC

Product: glutamine synthetase (glutamate ammonia ligase) (GS). (glnA-2)

Products: NA

Alternate protein names: GS; Glutamate--ammonia ligase [H]

Number of amino acids: Translated: 425; Mature: 424

Protein sequence:

>425_residues
MSKENIFDALKSGKIDYVRVEFVDILGNTKGRSLRRAEFENVINDNKGVDYPESLALMDYKDRPIKSRYEDIIAIPDLNT
FVAIPYLERTARVLSFLAQPDGLPYPYCSRSILNKAIEKLKEAGYTLQVSFEPTFYLLNSALNPADYSKAFSLEGLLEQQ
NFLKLLIKYLEEIDIKVETINKHYGPGQYEVKLSQKPVLEAADSLISSREVIRDTAKMNNVIATFMPKPFKDYPSSSMDI
TLSLQTVDGKDIMYDPNDSKGIGLSKIAYNFISGILEHLPSILSIAAPTVNSYKRFKEVVTPNMPGIGSERHYIVRLPSY
YKDTHQVEFRLADPLANPYILLASMIYAGLDGIERNLMANVNEYYGTLPQTLKESLSRLENDTYMKYNLGQDLISIYINI
KNIEIEEYESQITEWERDYYLKAGW

Sequences:

>Translated_425_residues
MSKENIFDALKSGKIDYVRVEFVDILGNTKGRSLRRAEFENVINDNKGVDYPESLALMDYKDRPIKSRYEDIIAIPDLNT
FVAIPYLERTARVLSFLAQPDGLPYPYCSRSILNKAIEKLKEAGYTLQVSFEPTFYLLNSALNPADYSKAFSLEGLLEQQ
NFLKLLIKYLEEIDIKVETINKHYGPGQYEVKLSQKPVLEAADSLISSREVIRDTAKMNNVIATFMPKPFKDYPSSSMDI
TLSLQTVDGKDIMYDPNDSKGIGLSKIAYNFISGILEHLPSILSIAAPTVNSYKRFKEVVTPNMPGIGSERHYIVRLPSY
YKDTHQVEFRLADPLANPYILLASMIYAGLDGIERNLMANVNEYYGTLPQTLKESLSRLENDTYMKYNLGQDLISIYINI
KNIEIEEYESQITEWERDYYLKAGW
>Mature_424_residues
SKENIFDALKSGKIDYVRVEFVDILGNTKGRSLRRAEFENVINDNKGVDYPESLALMDYKDRPIKSRYEDIIAIPDLNTF
VAIPYLERTARVLSFLAQPDGLPYPYCSRSILNKAIEKLKEAGYTLQVSFEPTFYLLNSALNPADYSKAFSLEGLLEQQN
FLKLLIKYLEEIDIKVETINKHYGPGQYEVKLSQKPVLEAADSLISSREVIRDTAKMNNVIATFMPKPFKDYPSSSMDIT
LSLQTVDGKDIMYDPNDSKGIGLSKIAYNFISGILEHLPSILSIAAPTVNSYKRFKEVVTPNMPGIGSERHYIVRLPSYY
KDTHQVEFRLADPLANPYILLASMIYAGLDGIERNLMANVNEYYGTLPQTLKESLSRLENDTYMKYNLGQDLISIYINIK
NIEIEEYESQITEWERDYYLKAGW

Specific function: Unknown

COG id: COG0174

COG function: function code E; Glutamine synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glutamine synthetase family [H]

Homologues:

Organism=Homo sapiens, GI221307485, Length=447, Percent_Identity=24.8322147651007, Blast_Score=119, Evalue=4e-27,
Organism=Escherichia coli, GI87081870, Length=441, Percent_Identity=26.7573696145125, Blast_Score=140, Evalue=2e-34,
Organism=Escherichia coli, GI1790301, Length=441, Percent_Identity=24.7165532879819, Blast_Score=91, Evalue=1e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008147
- InterPro:   IPR014746
- InterPro:   IPR008146
- InterPro:   IPR004809 [H]

Pfam domain/function: PF00120 Gln-synt_C; PF03951 Gln-synt_N [H]

EC number: =6.3.1.2 [H]

Molecular weight: Translated: 48585; Mature: 48454

Theoretical pI: Translated: 4.95; Mature: 4.95

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKENIFDALKSGKIDYVRVEFVDILGNTKGRSLRRAEFENVINDNKGVDYPESLALMDY
CCHHHHHHHHHCCCCEEEEEEEEEECCCCCCCHHHHHHHHHHHCCCCCCCCCCCEEEECC
KDRPIKSRYEDIIAIPDLNTFVAIPYLERTARVLSFLAQPDGLPYPYCSRSILNKAIEKL
CCCCHHHHHHCEEECCCCCCEEECHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHH
KEAGYTLQVSFEPTFYLLNSALNPADYSKAFSLEGLLEQQNFLKLLIKYLEEIDIKVETI
HHCCCEEEEECCCHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEE
NKHYGPGQYEVKLSQKPVLEAADSLISSREVIRDTAKMNNVIATFMPKPFKDYPSSSMDI
CCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCHHEECCCCCCCCCCCCCCEE
TLSLQTVDGKDIMYDPNDSKGIGLSKIAYNFISGILEHLPSILSIAAPTVNSYKRFKEVV
EEEEEEECCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
TPNMPGIGSERHYIVRLPSYYKDTHQVEFRLADPLANPYILLASMIYAGLDGIERNLMAN
CCCCCCCCCCCEEEEECCHHHCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHC
VNEYYGTLPQTLKESLSRLENDTYMKYNLGQDLISIYINIKNIEIEEYESQITEWERDYY
CHHHHCCCHHHHHHHHHHHCCCCEEEEECCHHEEEEEEEEECCCHHHHHHHHHHHHHCEE
LKAGW
EECCC
>Mature Secondary Structure 
SKENIFDALKSGKIDYVRVEFVDILGNTKGRSLRRAEFENVINDNKGVDYPESLALMDY
CHHHHHHHHHCCCCEEEEEEEEEECCCCCCCHHHHHHHHHHHCCCCCCCCCCCEEEECC
KDRPIKSRYEDIIAIPDLNTFVAIPYLERTARVLSFLAQPDGLPYPYCSRSILNKAIEKL
CCCCHHHHHHCEEECCCCCCEEECHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHH
KEAGYTLQVSFEPTFYLLNSALNPADYSKAFSLEGLLEQQNFLKLLIKYLEEIDIKVETI
HHCCCEEEEECCCHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEE
NKHYGPGQYEVKLSQKPVLEAADSLISSREVIRDTAKMNNVIATFMPKPFKDYPSSSMDI
CCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCHHEECCCCCCCCCCCCCCEE
TLSLQTVDGKDIMYDPNDSKGIGLSKIAYNFISGILEHLPSILSIAAPTVNSYKRFKEVV
EEEEEEECCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
TPNMPGIGSERHYIVRLPSYYKDTHQVEFRLADPLANPYILLASMIYAGLDGIERNLMAN
CCCCCCCCCCCEEEEECCHHHCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHC
VNEYYGTLPQTLKESLSRLENDTYMKYNLGQDLISIYINIKNIEIEEYESQITEWERDYY
CHHHHCCCHHHHHHHHHHHCCCCEEEEECCHHEEEEEEEEECCCHHHHHHHHHHHHHCEE
LKAGW
EECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11016950 [H]