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The map label for this gene is nagD-like [H]

Identifier: 15899113

GI number: 15899113

Start: 2149856

End: 2150650

Strand: Direct

Name: nagD-like [H]

Synonym: SSO2355

Alternate gene names: 15899113

Gene position: 2149856-2150650 (Clockwise)

Preceding gene: 15899112

Following gene: 15899114

Centisome position: 71.85

GC content: 36.35

Gene sequence:

>795_bases
ATGTCAGTACTTAACGGCTATCAATTAATAATAAGTGATGTAGATGGGGTAATAGTAAGAGAAGGAGATCCAATATGGGA
GAATATTCAAGCGCTAAGGAATATACAAAATAACGGAGTTAAGATCATATTTGTAACAAACAACTCTGGTTTTAGTAGGA
TCTTATTATCTAGGCAGTTATCATACTTAGGCCTTAAAGTTACCCCAGATATGATAATTACAAGTGGTTTAGCTGCAGCA
ATTTATATGAAAGAAAAACTCAATGTCAAATCAGTATTCGCAGTAGGCGAAGAGGGCCTTATTGAAGAATTGAAAAATCA
CGGTTTTTTAGTATTCTCAAGCGCAGAATCAGAGAGAATTTTACCAGACGCGGTCGTAATGGGATTAGATAGGTTAAGTA
CCTATGATAAACTGTCGTTAGCCATGAGGTGCATAAGCAAAGGATCGAAATTTATAGTAACAAATATGGACAGGCTTTGG
CCAGCTAAGGATGGATTAAAATTGGGTGCCGGTGCGTTAGCTAGTTCTATAATTTACGCGTTAAGAAGGGATCCGGACTT
CATAGCTGGGAAACCTAATACTTGGATAGTAGAAATAGCCATGCGGATTTCTAATGTTAAGAAGTTAGATAAGATTCTAG
TTATAGGAGATCAAATAGAGACTGATATCCAGATGGGGTACAATATAGGTGCCGACACTGCATTAGTCTTAACTGGAATA
TCAAACGTAGATGATGTTGATAGGAGTAATGTTAAGCCGAAATATGTAGTAAATACTTTATTAGACCTTTTGTGA

Upstream 100 bases:

>100_bases
GAAAACGTAGTCTATACTGCATTTGGGCTTTTTGGTTTTGTAAGTAACCAAGAAGAATTAGAGCAAAAAATTAAAGAGAA
GATTGAGGTGTTAATGCGAA

Downstream 100 bases:

>100_bases
AATTGTAGAAAGAATACTTAAAAACTATTACGCAAATATAAACATGTATGGAAAAGATCGAATACGACGCTGTTGTAATT
GGAGGAGGACTAGCAGGATT

Product: phosphatase, putative (nagD-like)

Products: 4-nitrophenol; phosphate

Alternate protein names: NA

Number of amino acids: Translated: 264; Mature: 263

Protein sequence:

>264_residues
MSVLNGYQLIISDVDGVIVREGDPIWENIQALRNIQNNGVKIIFVTNNSGFSRILLSRQLSYLGLKVTPDMIITSGLAAA
IYMKEKLNVKSVFAVGEEGLIEELKNHGFLVFSSAESERILPDAVVMGLDRLSTYDKLSLAMRCISKGSKFIVTNMDRLW
PAKDGLKLGAGALASSIIYALRRDPDFIAGKPNTWIVEIAMRISNVKKLDKILVIGDQIETDIQMGYNIGADTALVLTGI
SNVDDVDRSNVKPKYVVNTLLDLL

Sequences:

>Translated_264_residues
MSVLNGYQLIISDVDGVIVREGDPIWENIQALRNIQNNGVKIIFVTNNSGFSRILLSRQLSYLGLKVTPDMIITSGLAAA
IYMKEKLNVKSVFAVGEEGLIEELKNHGFLVFSSAESERILPDAVVMGLDRLSTYDKLSLAMRCISKGSKFIVTNMDRLW
PAKDGLKLGAGALASSIIYALRRDPDFIAGKPNTWIVEIAMRISNVKKLDKILVIGDQIETDIQMGYNIGADTALVLTGI
SNVDDVDRSNVKPKYVVNTLLDLL
>Mature_263_residues
SVLNGYQLIISDVDGVIVREGDPIWENIQALRNIQNNGVKIIFVTNNSGFSRILLSRQLSYLGLKVTPDMIITSGLAAAI
YMKEKLNVKSVFAVGEEGLIEELKNHGFLVFSSAESERILPDAVVMGLDRLSTYDKLSLAMRCISKGSKFIVTNMDRLWP
AKDGLKLGAGALASSIIYALRRDPDFIAGKPNTWIVEIAMRISNVKKLDKILVIGDQIETDIQMGYNIGADTALVLTGIS
NVDDVDRSNVKPKYVVNTLLDLL

Specific function: Unknown

COG id: COG0647

COG function: function code G; Predicted sugar phosphatases of the HAD superfamily

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAD-like hydrolase superfamily. NagD family [H]

Homologues:

Organism=Homo sapiens, GI10092677, Length=280, Percent_Identity=28.2142857142857, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI108796653, Length=288, Percent_Identity=26.3888888888889, Blast_Score=91, Evalue=9e-19,
Organism=Homo sapiens, GI14149777, Length=261, Percent_Identity=26.0536398467433, Blast_Score=75, Evalue=7e-14,
Organism=Escherichia coli, GI1786890, Length=254, Percent_Identity=27.9527559055118, Blast_Score=117, Evalue=1e-27,
Organism=Caenorhabditis elegans, GI17560956, Length=293, Percent_Identity=26.2798634812287, Blast_Score=78, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI17562458, Length=293, Percent_Identity=26.2798634812287, Blast_Score=78, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI17558880, Length=293, Percent_Identity=26.2798634812287, Blast_Score=77, Evalue=7e-15,
Organism=Caenorhabditis elegans, GI193210059, Length=276, Percent_Identity=25.7246376811594, Blast_Score=69, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6319965, Length=244, Percent_Identity=28.2786885245902, Blast_Score=104, Evalue=1e-23,
Organism=Drosophila melanogaster, GI24666141, Length=263, Percent_Identity=31.5589353612167, Blast_Score=113, Evalue=2e-25,
Organism=Drosophila melanogaster, GI24656326, Length=260, Percent_Identity=26.1538461538462, Blast_Score=87, Evalue=1e-17,
Organism=Drosophila melanogaster, GI24656330, Length=254, Percent_Identity=31.496062992126, Blast_Score=81, Evalue=8e-16,
Organism=Drosophila melanogaster, GI22026920, Length=248, Percent_Identity=27.4193548387097, Blast_Score=72, Evalue=3e-13,
Organism=Drosophila melanogaster, GI19920940, Length=231, Percent_Identity=27.2727272727273, Blast_Score=72, Evalue=4e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005834
- InterPro:   IPR023214
- InterPro:   IPR006357
- InterPro:   IPR006354
- InterPro:   IPR023215 [H]

Pfam domain/function: PF00702 Hydrolase [H]

EC number: 3.1.3.41

Molecular weight: Translated: 29032; Mature: 28901

Theoretical pI: Translated: 6.04; Mature: 6.04

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVLNGYQLIISDVDGVIVREGDPIWENIQALRNIQNNGVKIIFVTNNSGFSRILLSRQL
CCCCCCCEEEEECCCEEEEECCCCHHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHHH
SYLGLKVTPDMIITSGLAAAIYMKEKLNVKSVFAVGEEGLIEELKNHGFLVFSSAESERI
HHCEEEECHHHHHHHHHHHHHHHHHHCCHHHHHHCCCHHHHHHHHCCCEEEEECCCCCCC
LPDAVVMGLDRLSTYDKLSLAMRCISKGSKFIVTNMDRLWPAKDGLKLGAGALASSIIYA
CHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECHHHHCCCCCCCCHHHHHHHHHHHHH
LRRDPDFIAGKPNTWIVEIAMRISNVKKLDKILVIGDQIETDIQMGYNIGADTALVLTGI
HHCCCCCCCCCCCCEEEHHHHHHHHHHHHHHEEEECCCCCCHHHHCCCCCCCCEEEEECC
SNVDDVDRSNVKPKYVVNTLLDLL
CCCCCCCCCCCCHHHHHHHHHHHC
>Mature Secondary Structure 
SVLNGYQLIISDVDGVIVREGDPIWENIQALRNIQNNGVKIIFVTNNSGFSRILLSRQL
CCCCCCEEEEECCCEEEEECCCCHHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHHH
SYLGLKVTPDMIITSGLAAAIYMKEKLNVKSVFAVGEEGLIEELKNHGFLVFSSAESERI
HHCEEEECHHHHHHHHHHHHHHHHHHCCHHHHHHCCCHHHHHHHHCCCEEEEECCCCCCC
LPDAVVMGLDRLSTYDKLSLAMRCISKGSKFIVTNMDRLWPAKDGLKLGAGALASSIIYA
CHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECHHHHCCCCCCCCHHHHHHHHHHHHH
LRRDPDFIAGKPNTWIVEIAMRISNVKKLDKILVIGDQIETDIQMGYNIGADTALVLTGI
HHCCCCCCCCCCCCEEEHHHHHHHHHHHHHHEEEECCCCCCHHHHCCCCCCCCEEEEECC
SNVDDVDRSNVKPKYVVNTLLDLL
CCCCCCCCCCCCHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 4-nitrophenyl phosphate; H2O

Specific reaction: 4-nitrophenyl phosphate + H2O = 4-nitrophenol + phosphate

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA