Click here to switch to the map view.

The map label for this gene is 15898951

Identifier: 15898951

GI number: 15898951

Start: 1995866

End: 1996393

Strand: Direct

Name: 15898951

Synonym: SSO2171

Alternate gene names: NA

Gene position: 1995866-1996393 (Clockwise)

Preceding gene: 15898948

Following gene: 15898952

Centisome position: 66.7

GC content: 32.58

Gene sequence:

>528_bases
ATGTTAGAAGAGTCGAAGAATGCTTTAAGGGTATTTATAACTGGTAACCCCGGTGTTGGGAAAACTACAATATTACTCTT
TTTAATTAATAAATTAAGTGAGAATAATTACAAAGTTGCTGGATTTTATTGCCCAGAGGTGAGAGAGAATGGAAGAAGAA
TAGGTTTTAGAATAGTAGATATAACTACCAATGAAGGAGACTGGTTGGCTAAAGAAAACGCGCCTGGAAGAGTGAAAATA
GGGAAATATACAGTTTTAGAAGATAGTGCTAAAAGAATAACTGAGATTACATTGTCTAACATTAATAAGGCAGATGTTTT
AGCAATAGACGAAATTGGGCCAATGGAGTTAAAAATACCTACAATAAAGAAATTAATTGAGACTATTCTAAATAATCAAA
AACCTTTGATTGCAGTGTTACATAGGACACAAAAACCCATGGGAGGAAGAATCTACGTAATTACCGTTGAAAATAGGGAT
TCGATAAAGTACGAGATTTTGAATTACATATTAAGTAGCCTAGATTAA

Upstream 100 bases:

>100_bases
CTAAATTTAAGGCATTAGCCAGCTATAACTTGATCTGGATTACGAATATCTAAAATAAGTGATAAATAAAGATAAATCAG
TAGAGTCATTGATATAATCG

Downstream 100 bases:

>100_bases
CTTCTTCTATGGCCTTTTCTAAATTCTCTTCATTCAGATGGTATTATACGTTAAATATTTGCTCAACAAATATTCTCATA
ATGGTAATGCATGAATATAT

Product: putative NTPase

Products: NA

Alternate protein names: NTPase THEP1; Nucleoside triphosphate phosphohydrolase

Number of amino acids: Translated: 175; Mature: 175

Protein sequence:

>175_residues
MLEESKNALRVFITGNPGVGKTTILLFLINKLSENNYKVAGFYCPEVRENGRRIGFRIVDITTNEGDWLAKENAPGRVKI
GKYTVLEDSAKRITEITLSNINKADVLAIDEIGPMELKIPTIKKLIETILNNQKPLIAVLHRTQKPMGGRIYVITVENRD
SIKYEILNYILSSLD

Sequences:

>Translated_175_residues
MLEESKNALRVFITGNPGVGKTTILLFLINKLSENNYKVAGFYCPEVRENGRRIGFRIVDITTNEGDWLAKENAPGRVKI
GKYTVLEDSAKRITEITLSNINKADVLAIDEIGPMELKIPTIKKLIETILNNQKPLIAVLHRTQKPMGGRIYVITVENRD
SIKYEILNYILSSLD
>Mature_175_residues
MLEESKNALRVFITGNPGVGKTTILLFLINKLSENNYKVAGFYCPEVRENGRRIGFRIVDITTNEGDWLAKENAPGRVKI
GKYTVLEDSAKRITEITLSNINKADVLAIDEIGPMELKIPTIKKLIETILNNQKPLIAVLHRTQKPMGGRIYVITVENRD
SIKYEILNYILSSLD

Specific function: Has nucleotide phosphatase activity towards ATP, GTP, CTP, TTP and UTP. May hydrolyze nucleoside diphosphates with lower efficiency

COG id: COG1618

COG function: function code F; Predicted nucleotide kinase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the THEP1 NTPase family

Homologues:

Organism=Homo sapiens, GI14150100, Length=189, Percent_Identity=33.3333333333333, Blast_Score=75, Evalue=3e-14,
Organism=Drosophila melanogaster, GI85726488, Length=182, Percent_Identity=30.2197802197802, Blast_Score=73, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NTPTH_SULSO (Q97WP0)

Other databases:

- EMBL:   AE006641
- PIR:   C90386
- RefSeq:   NP_343556.1
- ProteinModelPortal:   Q97WP0
- SMR:   Q97WP0
- GeneID:   1453673
- GenomeReviews:   AE006641_GR
- KEGG:   sso:SSO2171
- NMPDR:   fig|273057.1.peg.1979
- HOGENOM:   HBG574935
- OMA:   MEFKSNE
- ProtClustDB:   PRK13695
- BioCyc:   SSOL273057:SSO2171-MONOMER
- HAMAP:   MF_00796
- InterPro:   IPR003593
- InterPro:   IPR004948
- SMART:   SM00382

Pfam domain/function: PF03266 DUF265

EC number: =3.6.1.15

Molecular weight: Translated: 19730; Mature: 19730

Theoretical pI: Translated: 9.56; Mature: 9.56

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLEESKNALRVFITGNPGVGKTTILLFLINKLSENNYKVAGFYCPEVRENGRRIGFRIVD
CCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHCCCCEEEEEEECCHHHCCCCEEEEEEEE
ITTNEGDWLAKENAPGRVKIGKYTVLEDSAKRITEITLSNINKADVLAIDEIGPMELKIP
EEECCCCEEEECCCCCEEEECEEEEECCCHHHHHHHHHCCCCCCCEEEECCCCCEEEECH
TIKKLIETILNNQKPLIAVLHRTQKPMGGRIYVITVENRDSIKYEILNYILSSLD
HHHHHHHHHHCCCCCEEEEEECCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHCC
>Mature Secondary Structure
MLEESKNALRVFITGNPGVGKTTILLFLINKLSENNYKVAGFYCPEVRENGRRIGFRIVD
CCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHCCCCEEEEEEECCHHHCCCCEEEEEEEE
ITTNEGDWLAKENAPGRVKIGKYTVLEDSAKRITEITLSNINKADVLAIDEIGPMELKIP
EEECCCCEEEECCCCCEEEECEEEEECCCHHHHHHHHHCCCCCCCEEEECCCCCEEEECH
TIKKLIETILNNQKPLIAVLHRTQKPMGGRIYVITVENRDSIKYEILNYILSSLD
HHHHHHHHHHCCCCCEEEEEECCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11427726