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The map label for this gene is oxlT [H]

Identifier: 15898911

GI number: 15898911

Start: 1953502

End: 1954794

Strand: Direct

Name: oxlT [H]

Synonym: SSO2127

Alternate gene names: 15898911

Gene position: 1953502-1954794 (Clockwise)

Preceding gene: 15898910

Following gene: 15898912

Centisome position: 65.29

GC content: 39.21

Gene sequence:

>1293_bases
ATGATGAGTAGTAAGTGGTTTGAAAAAGGATGGTTTAGGTGGATGCTAGTAGTAGGTGCAACTATTTCTATGGCACTTGT
TAGTGTGTATGAATATTCATGGACATTATATACTGTACCTCTAGGTAGAGTATTTCACGTAGCTCCAGGATCACCAGCCC
TAGGACTTACATATACAATATATATTATCGTCCAAGCATTATCGATGTTCGTTGCAGGTAGGATTGCGGATAGGTATGGT
CCTAGACTAATTTCCATGTTAGGTGGGATAATTACTGGCATTGGATATATTAGCTCTGCCTTTGCTAAATCCTTGCCTAT
ACTATATCTTACCTATGGTTTCGGAAGTATAGGAGTGGGCATAATATACGGTACTGCCATAAGTACTGCTGTCAAATGGT
TCCCTGATAAAAGAGGTCTAGCCACTGGAATTATAGAAATAGGTTTCGGTGGAGGATCATTCGCATTATCCCCTTTGATA
CAATATATTATCACCTCAATTAGTTACACAGCTGCATTCACTTACATGGGAATTGTGCAACTAATAGTTATAACTCTGCT
GGCGTTCTTCTTTGCTTATCCTCCTCCCCAATGGTTACCTAAGGGCTTTAATGCTGAGGAGTACGAGAAAAAACGTAAGA
TGATAAAGAGAAGCAAAAATGATTATACTGTATCGCAAATGGTAAAGACATGGCAATGGTGGGTAATTTATATAGCGTTT
TTCCTTATTGCTGGATCCGGCTTATCCATTATTGGACATTTAATACCATACGGTAGATCACTAGGATTTAGTATAGCTGC
TGTAATTGCGGTATTTTTATTTCCCTTTGCCAATGGGTTAGGAAGATTTGTTATGGGTACTGTATCTGACTATTTAGGAA
GACCTTATACTATGACGCTGTCATTTGGAATTAGTGGGATTTCCATGCTCTCAATAGCATTCATACCGAAGATTGCATCA
CTATACCTTGCTTTGATTTTCCTAACAGCATTCACGTGGGGACCATTATTCTCTTTGTTCCCACCACTGGTGGGTGACTA
TTATGGACCTAAACACTCTGGAGCTAATTATGGATTAACTTACACTGCAAAGGCGTTAGCAGGCATATTTGCCGGTTATG
GTGCATCAATATTGTTTACCTCATATGGCATAAAGGAGACATTAATTATAACTGGTTCAATGGCTATAATGTCTGCTATC
CTAGCCTTAACTCTAAGACCACCGAAAATACCTACTGCGCAGATTGCCGGTGCTGAAAGCCAGAAAGGTAGTATAGAGTC
CAAAACTAAGTAA

Upstream 100 bases:

>100_bases
ATTTTATGCAAGGAATTTTGATGAGCAATAGTTATATTTCTAATAAATATAGGCTAATTTTAGAAACAAAAGTTAAAACC
ATTTTTTACGTATAGAATGA

Downstream 100 bases:

>100_bases
TTTTTCTATAAAGGGTTTTTATCATAATTCCTATTATTTTTTATTTTTCCAGAAAATTTCTTAATAATCAAGTTAAACTT
TCTTCCCCATATCTTGCACA

Product: transport protein, permease

Products: NA

Alternate protein names: OFA; Oxalate:formate antiport protein; Oxalate:formate exchange protein [H]

Number of amino acids: Translated: 430; Mature: 430

Protein sequence:

>430_residues
MMSSKWFEKGWFRWMLVVGATISMALVSVYEYSWTLYTVPLGRVFHVAPGSPALGLTYTIYIIVQALSMFVAGRIADRYG
PRLISMLGGIITGIGYISSAFAKSLPILYLTYGFGSIGVGIIYGTAISTAVKWFPDKRGLATGIIEIGFGGGSFALSPLI
QYIITSISYTAAFTYMGIVQLIVITLLAFFFAYPPPQWLPKGFNAEEYEKKRKMIKRSKNDYTVSQMVKTWQWWVIYIAF
FLIAGSGLSIIGHLIPYGRSLGFSIAAVIAVFLFPFANGLGRFVMGTVSDYLGRPYTMTLSFGISGISMLSIAFIPKIAS
LYLALIFLTAFTWGPLFSLFPPLVGDYYGPKHSGANYGLTYTAKALAGIFAGYGASILFTSYGIKETLIITGSMAIMSAI
LALTLRPPKIPTAQIAGAESQKGSIESKTK

Sequences:

>Translated_430_residues
MMSSKWFEKGWFRWMLVVGATISMALVSVYEYSWTLYTVPLGRVFHVAPGSPALGLTYTIYIIVQALSMFVAGRIADRYG
PRLISMLGGIITGIGYISSAFAKSLPILYLTYGFGSIGVGIIYGTAISTAVKWFPDKRGLATGIIEIGFGGGSFALSPLI
QYIITSISYTAAFTYMGIVQLIVITLLAFFFAYPPPQWLPKGFNAEEYEKKRKMIKRSKNDYTVSQMVKTWQWWVIYIAF
FLIAGSGLSIIGHLIPYGRSLGFSIAAVIAVFLFPFANGLGRFVMGTVSDYLGRPYTMTLSFGISGISMLSIAFIPKIAS
LYLALIFLTAFTWGPLFSLFPPLVGDYYGPKHSGANYGLTYTAKALAGIFAGYGASILFTSYGIKETLIITGSMAIMSAI
LALTLRPPKIPTAQIAGAESQKGSIESKTK
>Mature_430_residues
MMSSKWFEKGWFRWMLVVGATISMALVSVYEYSWTLYTVPLGRVFHVAPGSPALGLTYTIYIIVQALSMFVAGRIADRYG
PRLISMLGGIITGIGYISSAFAKSLPILYLTYGFGSIGVGIIYGTAISTAVKWFPDKRGLATGIIEIGFGGGSFALSPLI
QYIITSISYTAAFTYMGIVQLIVITLLAFFFAYPPPQWLPKGFNAEEYEKKRKMIKRSKNDYTVSQMVKTWQWWVIYIAF
FLIAGSGLSIIGHLIPYGRSLGFSIAAVIAVFLFPFANGLGRFVMGTVSDYLGRPYTMTLSFGISGISMLSIAFIPKIAS
LYLALIFLTAFTWGPLFSLFPPLVGDYYGPKHSGANYGLTYTAKALAGIFAGYGASILFTSYGIKETLIITGSMAIMSAI
LALTLRPPKIPTAQIAGAESQKGSIESKTK

Specific function: Anion transporter that carries out the exchange of divalent oxalate with monovalent formate, the product of oxalate decarboxylation, at the plasma membrane, and in doing so catalyzes the vectorial portion of a proton-motive metabolic cycle that drives ATP

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. OFA (TC 2.A.1.11) family [H]

Homologues:

Organism=Homo sapiens, GI291621700, Length=333, Percent_Identity=24.6246246246246, Blast_Score=67, Evalue=5e-11,
Organism=Escherichia coli, GI1789969, Length=353, Percent_Identity=28.0453257790368, Blast_Score=134, Evalue=2e-32,
Organism=Drosophila melanogaster, GI281360217, Length=127, Percent_Identity=34.6456692913386, Blast_Score=69, Evalue=5e-12,
Organism=Drosophila melanogaster, GI28573971, Length=127, Percent_Identity=34.6456692913386, Blast_Score=69, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196
- InterPro:   IPR004741 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 46854; Mature: 46854

Theoretical pI: Translated: 10.11; Mature: 10.11

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMSSKWFEKGWFRWMLVVGATISMALVSVYEYSWTLYTVPLGRVFHVAPGSPALGLTYTI
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEEEECCCEEEECCCCCCCHHHHHH
YIIVQALSMFVAGRIADRYGPRLISMLGGIITGIGYISSAFAKSLPILYLTYGFGSIGVG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCHHHHH
IIYGTAISTAVKWFPDKRGLATGIIEIGFGGGSFALSPLIQYIITSISYTAAFTYMGIVQ
HHHHHHHHHHHHHCCCCCCCEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LIVITLLAFFFAYPPPQWLPKGFNAEEYEKKRKMIKRSKNDYTVSQMVKTWQWWVIYIAF
HHHHHHHHHHHCCCCHHHCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHH
FLIAGSGLSIIGHLIPYGRSLGFSIAAVIAVFLFPFANGLGRFVMGTVSDYLGRPYTMTL
HHHHCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEE
SFGISGISMLSIAFIPKIASLYLALIFLTAFTWGPLFSLFPPLVGDYYGPKHSGANYGLT
ECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHH
YTAKALAGIFAGYGASILFTSYGIKETLIITGSMAIMSAILALTLRPPKIPTAQIAGAES
HHHHHHHHHHHHCCHHHHHHHCCCCEEEEEECHHHHHHHHHHHHCCCCCCCCHHCCCCCC
QKGSIESKTK
CCCCCCCCCC
>Mature Secondary Structure
MMSSKWFEKGWFRWMLVVGATISMALVSVYEYSWTLYTVPLGRVFHVAPGSPALGLTYTI
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEEEECCCEEEECCCCCCCHHHHHH
YIIVQALSMFVAGRIADRYGPRLISMLGGIITGIGYISSAFAKSLPILYLTYGFGSIGVG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCHHHHH
IIYGTAISTAVKWFPDKRGLATGIIEIGFGGGSFALSPLIQYIITSISYTAAFTYMGIVQ
HHHHHHHHHHHHHCCCCCCCEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LIVITLLAFFFAYPPPQWLPKGFNAEEYEKKRKMIKRSKNDYTVSQMVKTWQWWVIYIAF
HHHHHHHHHHHCCCCHHHCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHH
FLIAGSGLSIIGHLIPYGRSLGFSIAAVIAVFLFPFANGLGRFVMGTVSDYLGRPYTMTL
HHHHCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEE
SFGISGISMLSIAFIPKIASLYLALIFLTAFTWGPLFSLFPPLVGDYYGPKHSGANYGLT
ECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHH
YTAKALAGIFAGYGASILFTSYGIKETLIITGSMAIMSAILALTLRPPKIPTAQIAGAES
HHHHHHHHHHHHCCHHHHHHHCCCCEEEEEECHHHHHHHHHHHHCCCCCCCCHHCCCCCC
QKGSIESKTK
CCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8636101; 9651403; 11919184; 11113128; 11274108; 11500368 [H]