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The map label for this gene is garD [H]

Identifier: 15898102

GI number: 15898102

Start: 1084762

End: 1085925

Strand: Reverse

Name: garD [H]

Synonym: SSO1259

Alternate gene names: 15898102

Gene position: 1085925-1084762 (Counterclockwise)

Preceding gene: 15898103

Following gene: 15898101

Centisome position: 36.29

GC content: 40.72

Gene sequence:

>1164_bases
ATGGAAAAACCAATAATAAGGGGTTACATTAGGGAAAACGGTAGTGTAGGAGTTAGGAATTACGTAGCTGTAATACCAGT
AGATGATTTATCAAATTCCGCTTCAATAGGGGTATCGAAATTAATTAGGGGTACGGTAGCTATTCCCCATCCCTACGGTA
GATTACAGTTTGGTAAGGATTTAGACTTACTCTTTCACGTATTATCTGGTACTGGTGCAAATCCAAACGTAGCTGCTGCA
ATAGTTATAGGAATTGAGGAAAACTGGGCAAATAAGGTAGCTGATAAGATAGCTGAGACTGGTAAGCCAGTTGAGGTCTT
CCCAGTTGAGGGAAATGGTGATTTGAAAGTAATAGAGAAAGCTAGCAGAAAGGCAAAGGAGTTCGTCCAAGAGGCTAGTG
AGAAGCAGAGGACTGAAGTGGACCTATCATCTTTAGTTTTAAGCATTAAGTGTGGCGAGAGCGATACAACATCTGGTTTA
GCGTCAAACCCAGCAACCGGTTATGCTGTGGATAAATTGATAGATTACGGTTCAACAGTGATGTTTGGAGAGACCTCAGA
GTTAACTGGTGCTGAAGACATTGTAGCCAGTAGGATACAAGATCCGGTTTTGAGGGATAAGTTCATGAGGATTTATAACG
AATACGTTGCTTTCATTGAGAGTCAAGGAGTCGACCTATTAGGCTCACAACCAACTGAGGGAAACATTAAGGGAGGATTA
TCGACTATAGAGGAAAAGGCTCTAGGGAATATTCAAAAATTAGGCACTAAACCAATTACTTGTGTGTTAGACTATTTGGA
TCCATTAGGGAAGGGATCATCTAGACTGTGTTTCGTTAATACTTCGTCTGCTGCTGCTGAGGCAGTTACGCTGTTTGCCG
CTAAGGGTTCAGTACTTCACTTGTTTACAACTGGGCAAGGGAATGTAGTTGGTCATCCGATAATTCCTGTAGTAAAAATT
TCCGCAAATCCAAAGACTATTGCAACAATGAGTGAGCATATTGACGTTGACGTTTCTGATTTACTTCAATTGAAGGTTAG
CTTAAAAGAAGCAGGGGAAAGAATATTCAACTATACGATTAGGGTTGCCAACGGTAGGTTAACTTCAGCGGAGATATTAC
AACATGAGGAGTTCTCTCCAATAAAGCTTTACATAAGTGCTTAA

Upstream 100 bases:

>100_bases
TTGTAATAAAGTATGGTAGACCAATAGGGTCTGCTATAAAGGATATTAAAGTAGGAGAACATGTGCACGTACACAATATA
AGATCTAACAGGTGGGGTAA

Downstream 100 bases:

>100_bases
AGATGAAAGTTAAGCCTTTTTCTTTATCCATCCCCTTTAATACTGAACCTCCCTCTGATTGGAAGGATGCGTGGGATGTG
CAGCTCTACGTTAAAGTGGA

Product: galactarate dehydratase, putative (garD)

Products: NA

Alternate protein names: Altronic acid hydratase [H]

Number of amino acids: Translated: 387; Mature: 387

Protein sequence:

>387_residues
MEKPIIRGYIRENGSVGVRNYVAVIPVDDLSNSASIGVSKLIRGTVAIPHPYGRLQFGKDLDLLFHVLSGTGANPNVAAA
IVIGIEENWANKVADKIAETGKPVEVFPVEGNGDLKVIEKASRKAKEFVQEASEKQRTEVDLSSLVLSIKCGESDTTSGL
ASNPATGYAVDKLIDYGSTVMFGETSELTGAEDIVASRIQDPVLRDKFMRIYNEYVAFIESQGVDLLGSQPTEGNIKGGL
STIEEKALGNIQKLGTKPITCVLDYLDPLGKGSSRLCFVNTSSAAAEAVTLFAAKGSVLHLFTTGQGNVVGHPIIPVVKI
SANPKTIATMSEHIDVDVSDLLQLKVSLKEAGERIFNYTIRVANGRLTSAEILQHEEFSPIKLYISA

Sequences:

>Translated_387_residues
MEKPIIRGYIRENGSVGVRNYVAVIPVDDLSNSASIGVSKLIRGTVAIPHPYGRLQFGKDLDLLFHVLSGTGANPNVAAA
IVIGIEENWANKVADKIAETGKPVEVFPVEGNGDLKVIEKASRKAKEFVQEASEKQRTEVDLSSLVLSIKCGESDTTSGL
ASNPATGYAVDKLIDYGSTVMFGETSELTGAEDIVASRIQDPVLRDKFMRIYNEYVAFIESQGVDLLGSQPTEGNIKGGL
STIEEKALGNIQKLGTKPITCVLDYLDPLGKGSSRLCFVNTSSAAAEAVTLFAAKGSVLHLFTTGQGNVVGHPIIPVVKI
SANPKTIATMSEHIDVDVSDLLQLKVSLKEAGERIFNYTIRVANGRLTSAEILQHEEFSPIKLYISA
>Mature_387_residues
MEKPIIRGYIRENGSVGVRNYVAVIPVDDLSNSASIGVSKLIRGTVAIPHPYGRLQFGKDLDLLFHVLSGTGANPNVAAA
IVIGIEENWANKVADKIAETGKPVEVFPVEGNGDLKVIEKASRKAKEFVQEASEKQRTEVDLSSLVLSIKCGESDTTSGL
ASNPATGYAVDKLIDYGSTVMFGETSELTGAEDIVASRIQDPVLRDKFMRIYNEYVAFIESQGVDLLGSQPTEGNIKGGL
STIEEKALGNIQKLGTKPITCVLDYLDPLGKGSSRLCFVNTSSAAAEAVTLFAAKGSVLHLFTTGQGNVVGHPIIPVVKI
SANPKTIATMSEHIDVDVSDLLQLKVSLKEAGERIFNYTIRVANGRLTSAEILQHEEFSPIKLYISA

Specific function: Hexuronate conversion to KDG. [C]

COG id: COG2721

COG function: function code G; Altronate dehydratase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the uxaA family [H]

Homologues:

Organism=Escherichia coli, GI1789475, Length=390, Percent_Identity=26.9230769230769, Blast_Score=125, Evalue=5e-30,
Organism=Escherichia coli, GI1789516, Length=251, Percent_Identity=28.6852589641434, Blast_Score=119, Evalue=3e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007392
- InterPro:   IPR013974 [H]

Pfam domain/function: PF04295 GD_AH_C; PF08666 SAF [H]

EC number: =4.2.1.7 [H]

Molecular weight: Translated: 41490; Mature: 41490

Theoretical pI: Translated: 5.31; Mature: 5.31

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEKPIIRGYIRENGSVGVRNYVAVIPVDDLSNSASIGVSKLIRGTVAIPHPYGRLQFGKD
CCCCCEEHEEECCCCCCCCCEEEEEEECCCCCCCHHHHHHHHHCCEECCCCCCCCCCCCC
LDLLFHVLSGTGANPNVAAAIVIGIEENWANKVADKIAETGKPVEVFPVEGNGDLKVIEK
HHHHHHHHHCCCCCCCEEEEEEEEECHHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHH
ASRKAKEFVQEASEKQRTEVDLSSLVLSIKCGESDTTSGLASNPATGYAVDKLIDYGSTV
HHHHHHHHHHHHHHHHHHHCCHHHEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHCCCEE
MFGETSELTGAEDIVASRIQDPVLRDKFMRIYNEYVAFIESQGVDLLGSQPTEGNIKGGL
EECCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCEECCCCCCCCCCCCCH
STIEEKALGNIQKLGTKPITCVLDYLDPLGKGSSRLCFVNTSSAAAEAVTLFAAKGSVLH
HHHHHHHHCCHHHHCCCCHHHHHHHHHCCCCCCCEEEEEECCCHHHHEEEEEEECCCEEE
LFTTGQGNVVGHPIIPVVKISANPKTIATMSEHIDVDVSDLLQLKVSLKEAGERIFNYTI
EEECCCCCEECCCCEEEEEECCCCCEEEEHHHHCCCCHHHHHHHHHHHHHHHHHHEEEEE
RVANGRLTSAEILQHEEFSPIKLYISA
EEECCCCCHHHHHHCCCCCCEEEEEEC
>Mature Secondary Structure
MEKPIIRGYIRENGSVGVRNYVAVIPVDDLSNSASIGVSKLIRGTVAIPHPYGRLQFGKD
CCCCCEEHEEECCCCCCCCCEEEEEEECCCCCCCHHHHHHHHHCCEECCCCCCCCCCCCC
LDLLFHVLSGTGANPNVAAAIVIGIEENWANKVADKIAETGKPVEVFPVEGNGDLKVIEK
HHHHHHHHHCCCCCCCEEEEEEEEECHHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHH
ASRKAKEFVQEASEKQRTEVDLSSLVLSIKCGESDTTSGLASNPATGYAVDKLIDYGSTV
HHHHHHHHHHHHHHHHHHHCCHHHEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHCCCEE
MFGETSELTGAEDIVASRIQDPVLRDKFMRIYNEYVAFIESQGVDLLGSQPTEGNIKGGL
EECCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCEECCCCCCCCCCCCCH
STIEEKALGNIQKLGTKPITCVLDYLDPLGKGSSRLCFVNTSSAAAEAVTLFAAKGSVLH
HHHHHHHHCCHHHHCCCCHHHHHHHHHCCCCCCCEEEEEECCCHHHHEEEEEEECCCEEE
LFTTGQGNVVGHPIIPVVKISANPKTIATMSEHIDVDVSDLLQLKVSLKEAGERIFNYTI
EEECCCCCEECCCCEEEEEECCCCCEEEEHHHHCCCCHHHHHHHHHHHHHHHHHHEEEEE
RVANGRLTSAEILQHEEFSPIKLYISA
EEECCCCCHHHHHHCCCCCCEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9579062; 9384377 [H]