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The map label for this gene is fabG-1 [H]

Identifier: 15897853

GI number: 15897853

Start: 833436

End: 834233

Strand: Direct

Name: fabG-1 [H]

Synonym: SSO0975

Alternate gene names: 15897853

Gene position: 833436-834233 (Clockwise)

Preceding gene: 15897852

Following gene: 15897854

Centisome position: 27.85

GC content: 35.71

Gene sequence:

>798_bases
ATGAACATCAATATTTCTGGTAAAAGAGTCCTCGTTACAGCATCCACAGAAGGCATTGGTAGGGGGATTGCAGAGGCTTT
TTTAAGAGAAGGATGCAACGTTGTAATATCTTCTAGGAATAAAGATAAAATAGAAAAAGCTATTTTAGAAATGAGAAAAA
TAGGACCATCAGTATGGGGCTTTCCAGCAGATCTAACTGATTTTAAGTCTCTAGAGGAGTTAGTTGGCTACGCTTTAAAG
ATCATGAACGGAATCGACATTTTGGTTGTAAACTCTGGAAATCCTCCTAAAGAGCCTTCCTATTTTTTTGAGAACACTAT
GGAGGATTGGGAATATGCTACTAAACTGTATCTATTAAGTGCAATAAAACTTACAAATCTAGTATATCAATACATGAAGG
CTCAAAGATGGGGTAGAATATTCTTCTTATCCTCATGGACAATCAAAGAGCCTCAACGAATATTCTCGTTAGCAGATATT
ACAAGAGCACCATTAATTCAGATGGCAAAACTACTTAGCAAAGAATTGGGGGAATACAACGTAAACGTTAACGTAATCTT
AATGGGTAGTTTTGAAACTGAAGGAGCTAAGAGATCCTTAAAAAAATATGCAGAAAAAGTTGGTCAACCATTAGATGTTA
TTTGGAAGAGGGAGGTAATTTCTCAAATTCCTATTGGAAGGACTGGGGACATAAAGAATGAGTTAGGTTCTCTTTTGGTA
TTTTTATCATCAGACTACGCAGGATATATTAATGGGACATCAATTCTAATAGATGGTGGAATGTCAAGAGCGATTTAA

Upstream 100 bases:

>100_bases
AGAAGCATTAGGATATTCTGAGGCCGATTTCATCTCAGTTGTAGAAGTCTTCAAGAAACTCTCACCTAAAACCTAAAAAT
CTCCTTTTTATACCTAAATT

Downstream 100 bases:

>100_bases
GGGCTAAAATAAACCTTTAATATTACCCTTGAAGGACTTAAGGTATTATACTTCATCTAACTCATGGAAAGGTTTATAAA
ATTAGTCCTATAGTAGTATT

Product: 3-oxoacyl-(acyl carrier protein) reductase (fabG-1)

Products: NA

Alternate protein names: 3-ketoacyl-acyl carrier protein reductase [H]

Number of amino acids: Translated: 265; Mature: 265

Protein sequence:

>265_residues
MNINISGKRVLVTASTEGIGRGIAEAFLREGCNVVISSRNKDKIEKAILEMRKIGPSVWGFPADLTDFKSLEELVGYALK
IMNGIDILVVNSGNPPKEPSYFFENTMEDWEYATKLYLLSAIKLTNLVYQYMKAQRWGRIFFLSSWTIKEPQRIFSLADI
TRAPLIQMAKLLSKELGEYNVNVNVILMGSFETEGAKRSLKKYAEKVGQPLDVIWKREVISQIPIGRTGDIKNELGSLLV
FLSSDYAGYINGTSILIDGGMSRAI

Sequences:

>Translated_265_residues
MNINISGKRVLVTASTEGIGRGIAEAFLREGCNVVISSRNKDKIEKAILEMRKIGPSVWGFPADLTDFKSLEELVGYALK
IMNGIDILVVNSGNPPKEPSYFFENTMEDWEYATKLYLLSAIKLTNLVYQYMKAQRWGRIFFLSSWTIKEPQRIFSLADI
TRAPLIQMAKLLSKELGEYNVNVNVILMGSFETEGAKRSLKKYAEKVGQPLDVIWKREVISQIPIGRTGDIKNELGSLLV
FLSSDYAGYINGTSILIDGGMSRAI
>Mature_265_residues
MNINISGKRVLVTASTEGIGRGIAEAFLREGCNVVISSRNKDKIEKAILEMRKIGPSVWGFPADLTDFKSLEELVGYALK
IMNGIDILVVNSGNPPKEPSYFFENTMEDWEYATKLYLLSAIKLTNLVYQYMKAQRWGRIFFLSSWTIKEPQRIFSLADI
TRAPLIQMAKLLSKELGEYNVNVNVILMGSFETEGAKRSLKKYAEKVGQPLDVIWKREVISQIPIGRTGDIKNELGSLLV
FLSSDYAGYINGTSILIDGGMSRAI

Specific function: 7-Alpha-Dehydroxylation Of Cholic Acid, Yielding Deoxycholic Acid And Lithocholic Acid, Respectively. Highest Affinity With Taurochenodeoxycholic Acid. [C]

COG id: COG1028

COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI32483357, Length=265, Percent_Identity=28.6792452830189, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI5031737, Length=259, Percent_Identity=26.6409266409266, Blast_Score=91, Evalue=1e-18,
Organism=Homo sapiens, GI126723750, Length=263, Percent_Identity=25.8555133079848, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI126723191, Length=186, Percent_Identity=30.1075268817204, Blast_Score=83, Evalue=3e-16,
Organism=Homo sapiens, GI33667109, Length=187, Percent_Identity=28.3422459893048, Blast_Score=82, Evalue=4e-16,
Organism=Homo sapiens, GI7705925, Length=263, Percent_Identity=25.8555133079848, Blast_Score=82, Evalue=6e-16,
Organism=Homo sapiens, GI4503301, Length=235, Percent_Identity=30.2127659574468, Blast_Score=72, Evalue=3e-13,
Organism=Homo sapiens, GI32455239, Length=209, Percent_Identity=24.8803827751196, Blast_Score=66, Evalue=3e-11,
Organism=Homo sapiens, GI5031765, Length=209, Percent_Identity=24.8803827751196, Blast_Score=66, Evalue=3e-11,
Organism=Escherichia coli, GI1787905, Length=259, Percent_Identity=25.4826254826255, Blast_Score=93, Evalue=2e-20,
Organism=Escherichia coli, GI87082100, Length=260, Percent_Identity=29.6153846153846, Blast_Score=92, Evalue=5e-20,
Organism=Escherichia coli, GI1787335, Length=259, Percent_Identity=27.4131274131274, Blast_Score=89, Evalue=4e-19,
Organism=Escherichia coli, GI1790717, Length=262, Percent_Identity=23.2824427480916, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI1789208, Length=259, Percent_Identity=25.8687258687259, Blast_Score=82, Evalue=3e-17,
Organism=Escherichia coli, GI87082160, Length=261, Percent_Identity=27.2030651340996, Blast_Score=78, Evalue=7e-16,
Organism=Escherichia coli, GI1789378, Length=258, Percent_Identity=25.968992248062, Blast_Score=62, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI17561402, Length=264, Percent_Identity=28.4090909090909, Blast_Score=99, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI17560676, Length=261, Percent_Identity=28.735632183908, Blast_Score=98, Evalue=4e-21,
Organism=Caenorhabditis elegans, GI17562910, Length=269, Percent_Identity=30.4832713754647, Blast_Score=89, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17560150, Length=263, Percent_Identity=28.5171102661597, Blast_Score=85, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI17562906, Length=269, Percent_Identity=27.5092936802974, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17562990, Length=266, Percent_Identity=27.4436090225564, Blast_Score=79, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17562904, Length=272, Percent_Identity=28.3088235294118, Blast_Score=78, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI193204405, Length=274, Percent_Identity=27.007299270073, Blast_Score=73, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17562908, Length=271, Percent_Identity=25.830258302583, Blast_Score=71, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI17551412, Length=279, Percent_Identity=27.2401433691756, Blast_Score=71, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI72000259, Length=268, Percent_Identity=27.6119402985075, Blast_Score=71, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI17538480, Length=275, Percent_Identity=25.4545454545455, Blast_Score=71, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI17531453, Length=266, Percent_Identity=27.4436090225564, Blast_Score=67, Evalue=9e-12,
Organism=Caenorhabditis elegans, GI17563726, Length=266, Percent_Identity=26.6917293233083, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17559104, Length=267, Percent_Identity=25.0936329588015, Blast_Score=66, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6324126, Length=262, Percent_Identity=25.5725190839695, Blast_Score=64, Evalue=2e-11,
Organism=Drosophila melanogaster, GI21355319, Length=258, Percent_Identity=27.1317829457364, Blast_Score=98, Evalue=5e-21,
Organism=Drosophila melanogaster, GI24639444, Length=263, Percent_Identity=25.8555133079848, Blast_Score=82, Evalue=5e-16,
Organism=Drosophila melanogaster, GI23397609, Length=258, Percent_Identity=26.3565891472868, Blast_Score=68, Evalue=6e-12,
Organism=Drosophila melanogaster, GI21358495, Length=200, Percent_Identity=26.5, Blast_Score=67, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011284
- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.1.1.100 [H]

Molecular weight: Translated: 29674; Mature: 29674

Theoretical pI: Translated: 9.36; Mature: 9.36

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNINISGKRVLVTASTEGIGRGIAEAFLREGCNVVISSRNKDKIEKAILEMRKIGPSVWG
CCCCCCCCEEEEEECCCHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHCCCCCCC
FPADLTDFKSLEELVGYALKIMNGIDILVVNSGNPPKEPSYFFENTMEDWEYATKLYLLS
CCCCHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
AIKLTNLVYQYMKAQRWGRIFFLSSWTIKEPQRIFSLADITRAPLIQMAKLLSKELGEYN
HHHHHHHHHHHHHHHHCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
VNVNVILMGSFETEGAKRSLKKYAEKVGQPLDVIWKREVISQIPIGRTGDIKNELGSLLV
CCEEEEEEECCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHEEE
FLSSDYAGYINGTSILIDGGMSRAI
HCCCCCCCEECCCEEEEECCHHCCC
>Mature Secondary Structure
MNINISGKRVLVTASTEGIGRGIAEAFLREGCNVVISSRNKDKIEKAILEMRKIGPSVWG
CCCCCCCCEEEEEECCCHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHCCCCCCC
FPADLTDFKSLEELVGYALKIMNGIDILVVNSGNPPKEPSYFFENTMEDWEYATKLYLLS
CCCCHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
AIKLTNLVYQYMKAQRWGRIFFLSSWTIKEPQRIFSLADITRAPLIQMAKLLSKELGEYN
HHHHHHHHHHHHHHHHCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
VNVNVILMGSFETEGAKRSLKKYAEKVGQPLDVIWKREVISQIPIGRTGDIKNELGSLLV
CCEEEEEEECCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHEEE
FLSSDYAGYINGTSILIDGGMSRAI
HCCCCCCCEECCCEEEEECCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9537320 [H]