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The map label for this gene is moaC

Identifier: 15897672

GI number: 15897672

Start: 655295

End: 655744

Strand: Reverse

Name: moaC

Synonym: SSO0770

Alternate gene names: 15897672

Gene position: 655744-655295 (Counterclockwise)

Preceding gene: 15897673

Following gene: 15897666

Centisome position: 21.91

GC content: 32.44

Gene sequence:

>450_bases
ATGAGTTCCGAAGCTAAGATGGTAGATATATCTCAAAAGGAAACTGTATTAAGAGAGGCTGAAGCTGAGGGATTCATTAA
ACTAAAGAACGATACTATAAAGAGAATTATAGAAAATGAAATAGAGAAGGGTAACGTAATTACTGTTGCTAAGACTGCAG
GGATTATGGCTGCAAAGAAAACTTCTGAGCTTCTACCTCTATGCCATTTAATACCATTAGAAAATGTTGATATTGATATA
AAAATTGAGAATAGTGGTATAAGAGTTAGATCTAAGGTGAAGGCCCATTATAAGACTGGAGTAGAAATGGAGGCACTAGT
TGCTACATCTATCTCCTTGTTAACTATTTGGGATATGGTAAAAAAATATGAAAAAGATGAGAACGGAAAATATCCATATA
CCATGATTGATGATATAAAAGTAATAGATAAAATAAAGGAGAAAGACTAA

Upstream 100 bases:

>100_bases
TTAATTGAAGTAATAGGTAGTGATAAAAAAATAGTAAGATTAAATTACTCTAACCCTAAAGTAGTAATCTTGATTAACCT
ATTAGAAGAGCTGGATAAAA

Downstream 100 bases:

>100_bases
GATTTAGATATGGAACTAAGATACTCCTTTTCTTTCGTATTTAAATTAAGATGTTTATCGTATTTTTTATAGAATAGTAG
GAAAAATGGATATGTGTCAT

Product: putative molybdenum cofactor biosynthesis protein MoaC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 149; Mature: 148

Protein sequence:

>149_residues
MSSEAKMVDISQKETVLREAEAEGFIKLKNDTIKRIIENEIEKGNVITVAKTAGIMAAKKTSELLPLCHLIPLENVDIDI
KIENSGIRVRSKVKAHYKTGVEMEALVATSISLLTIWDMVKKYEKDENGKYPYTMIDDIKVIDKIKEKD

Sequences:

>Translated_149_residues
MSSEAKMVDISQKETVLREAEAEGFIKLKNDTIKRIIENEIEKGNVITVAKTAGIMAAKKTSELLPLCHLIPLENVDIDI
KIENSGIRVRSKVKAHYKTGVEMEALVATSISLLTIWDMVKKYEKDENGKYPYTMIDDIKVIDKIKEKD
>Mature_148_residues
SSEAKMVDISQKETVLREAEAEGFIKLKNDTIKRIIENEIEKGNVITVAKTAGIMAAKKTSELLPLCHLIPLENVDIDIK
IENSGIRVRSKVKAHYKTGVEMEALVATSISLLTIWDMVKKYEKDENGKYPYTMIDDIKVIDKIKEKD

Specific function: Together with moaA, is involved in the conversion of a guanosine derivative (5'-GTP) into molybdopterin precursor Z

COG id: COG0315

COG function: function code H; Molybdenum cofactor biosynthesis enzyme

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the moaC family

Homologues:

Organism=Escherichia coli, GI1787001, Length=127, Percent_Identity=43.3070866141732, Blast_Score=114, Evalue=3e-27,
Organism=Caenorhabditis elegans, GI32566331, Length=122, Percent_Identity=48.3606557377049, Blast_Score=107, Evalue=2e-24,
Organism=Drosophila melanogaster, GI28574492, Length=123, Percent_Identity=43.0894308943089, Blast_Score=105, Evalue=1e-23,
Organism=Drosophila melanogaster, GI28574490, Length=126, Percent_Identity=42.8571428571429, Blast_Score=103, Evalue=4e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MOAC_SULSO (Q9UXF7)

Other databases:

- EMBL:   Y18930
- EMBL:   AE006641
- PIR:   D90226
- RefSeq:   NP_342277.1
- ProteinModelPortal:   Q9UXF7
- SMR:   Q9UXF7
- GeneID:   1455034
- GenomeReviews:   AE006641_GR
- KEGG:   sso:SSO0770
- NMPDR:   fig|273057.1.peg.700
- HOGENOM:   HBG605231
- OMA:   PMCHPLM
- ProtClustDB:   PRK12343
- BioCyc:   SSOL273057:SSO0770-MONOMER
- HAMAP:   MF_01224_A
- InterPro:   IPR023045
- InterPro:   IPR023047
- InterPro:   IPR002820
- Gene3D:   G3DSA:3.30.70.640
- TIGRFAMs:   TIGR00581

Pfam domain/function: PF01967 MoaC; SSF55040 MoaC

EC number: NA

Molecular weight: Translated: 16838; Mature: 16707

Theoretical pI: Translated: 6.55; Mature: 6.55

Prosite motif: NA

Important sites: ACT_SITE 118-118

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSEAKMVDISQKETVLREAEAEGFIKLKNDTIKRIIENEIEKGNVITVAKTAGIMAAKK
CCCCCCEEECCHHHHHHHHHCCCCEEEECHHHHHHHHHHHCCCCCEEEEEECCCEEHHHC
TSELLPLCHLIPLENVDIDIKIENSGIRVRSKVKAHYKTGVEMEALVATSISLLTIWDMV
HHHHHHHHHHCCCCCCEEEEEECCCCEEEHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
KKYEKDENGKYPYTMIDDIKVIDKIKEKD
HHHCCCCCCCCCEEEHHHHHHHHHHHCCC
>Mature Secondary Structure 
SSEAKMVDISQKETVLREAEAEGFIKLKNDTIKRIIENEIEKGNVITVAKTAGIMAAKK
CCCCCEEECCHHHHHHHHHCCCCEEEECHHHHHHHHHHHCCCCCEEEEEECCCEEHHHC
TSELLPLCHLIPLENVDIDIKIENSGIRVRSKVKAHYKTGVEMEALVATSISLLTIWDMV
HHHHHHHHHHCCCCCCEEEEEECCCCEEEHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
KKYEKDENGKYPYTMIDDIKVIDKIKEKD
HHHCCCCCCCCCEEEHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Involved in molybdopterin biosynthesis [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10701121; 11427726