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The map label for this gene is psmB1 [H]

Identifier: 15897668

GI number: 15897668

Start: 651906

End: 652583

Strand: Direct

Name: psmB1 [H]

Synonym: SSO0766

Alternate gene names: 15897668

Gene position: 651906-652583 (Clockwise)

Preceding gene: 15897667

Following gene: 15897669

Centisome position: 21.79

GC content: 34.96

Gene sequence:

>678_bases
ATGAACCCTAAATTAACTGTCACCTTTTTATTCTTGCTTTTAATGGTAATTATGGGGAATGAGTTGCAATTAGAAAATAA
GATACTTAAGGGAACTACAACTGTAGGAATTAGAGTAAATGATGGAGTAATCCTTGCGGCAGATAGAAGAGCTAGTGCAG
GGTTTTTCGTAGCTAATAAAATGGTTAGAAAAGTATTATATATTACAGATAAAATCGGAATAACTACCGCAGGTAGTGTA
GCAGATTTACAGTTTATATACGATGTATTGAAAAATATATATCATTATAATAGTATTACTAAATACGGGCCAATTTCTAT
AAAGGGAATTGCAACCAGGCTAGCAAATGTATTATCTGCAACAAAATATTTTCCCTATATCGTTCAAATCTTGATAGGTG
GTTACGATGATCAGCCAAGATTATTCAACTTGGATTATTTAGGCGATATAACTGAAGAAAATTACGTCGCAACTGGTTCT
GGTTCTCCAGTAGCTATGGGAGTGCTAGAAGATGAGTATAATCCCAAAATGACTTTAGATGAGGCAGCTGACCTAGCTAA
GAGAGCTGTGTTCTCAGCAATAAAGCGGGATTCCTTTACGGGTACAGGTGTTATAGTAGCAAAAATTCACAGTAAAGGAC
ACGAGGAATTAGAGTTCTACTTAAATAAGAAGATGTGA

Upstream 100 bases:

>100_bases
GGTTTAATGATAAGCGGAGAATTGTATAAAGACGGGGATTTACTTGAAGTCGCTGAATATATTTTAAACATTGTAGGAAA
ACATTAACGATCTACTGGGA

Downstream 100 bases:

>100_bases
AGCGTTTTTAATTTTGAATAGTGAAAGTATATATTCGATGAGAGTAGTATCTTCAGCCTTTAAGAATGAGGATTTTATAC
CTATTAAATATACTTGTGAT

Product: proteasome subunit

Products: NA

Alternate protein names: 20S proteasome beta subunit 1; Proteasome core protein PsmB 1 [H]

Number of amino acids: Translated: 225; Mature: 225

Protein sequence:

>225_residues
MNPKLTVTFLFLLLMVIMGNELQLENKILKGTTTVGIRVNDGVILAADRRASAGFFVANKMVRKVLYITDKIGITTAGSV
ADLQFIYDVLKNIYHYNSITKYGPISIKGIATRLANVLSATKYFPYIVQILIGGYDDQPRLFNLDYLGDITEENYVATGS
GSPVAMGVLEDEYNPKMTLDEAADLAKRAVFSAIKRDSFTGTGVIVAKIHSKGHEELEFYLNKKM

Sequences:

>Translated_225_residues
MNPKLTVTFLFLLLMVIMGNELQLENKILKGTTTVGIRVNDGVILAADRRASAGFFVANKMVRKVLYITDKIGITTAGSV
ADLQFIYDVLKNIYHYNSITKYGPISIKGIATRLANVLSATKYFPYIVQILIGGYDDQPRLFNLDYLGDITEENYVATGS
GSPVAMGVLEDEYNPKMTLDEAADLAKRAVFSAIKRDSFTGTGVIVAKIHSKGHEELEFYLNKKM
>Mature_225_residues
MNPKLTVTFLFLLLMVIMGNELQLENKILKGTTTVGIRVNDGVILAADRRASAGFFVANKMVRKVLYITDKIGITTAGSV
ADLQFIYDVLKNIYHYNSITKYGPISIKGIATRLANVLSATKYFPYIVQILIGGYDDQPRLFNLDYLGDITEENYVATGS
GSPVAMGVLEDEYNPKMTLDEAADLAKRAVFSAIKRDSFTGTGVIVAKIHSKGHEELEFYLNKKM

Specific function: Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation [H]

COG id: COG0638

COG function: function code O; 20S proteasome, alpha and beta subunits

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase T1B family [H]

Homologues:

Organism=Homo sapiens, GI4506201, Length=188, Percent_Identity=31.9148936170213, Blast_Score=96, Evalue=3e-20,
Organism=Homo sapiens, GI4758970, Length=204, Percent_Identity=31.8627450980392, Blast_Score=93, Evalue=2e-19,
Organism=Homo sapiens, GI73747875, Length=186, Percent_Identity=31.7204301075269, Blast_Score=93, Evalue=2e-19,
Organism=Homo sapiens, GI153791216, Length=198, Percent_Identity=31.8181818181818, Blast_Score=87, Evalue=1e-17,
Organism=Homo sapiens, GI4506203, Length=206, Percent_Identity=30.0970873786408, Blast_Score=81, Evalue=7e-16,
Organism=Homo sapiens, GI4506191, Length=190, Percent_Identity=31.5789473684211, Blast_Score=76, Evalue=2e-14,
Organism=Homo sapiens, GI4506193, Length=218, Percent_Identity=27.0642201834862, Blast_Score=75, Evalue=6e-14,
Organism=Homo sapiens, GI23110925, Length=192, Percent_Identity=26.0416666666667, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI22538465, Length=187, Percent_Identity=26.7379679144385, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI22538467, Length=220, Percent_Identity=25.9090909090909, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17508499, Length=212, Percent_Identity=32.0754716981132, Blast_Score=100, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI17541700, Length=210, Percent_Identity=28.5714285714286, Blast_Score=91, Evalue=6e-19,
Organism=Caenorhabditis elegans, GI17508495, Length=182, Percent_Identity=31.8681318681319, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17508491, Length=167, Percent_Identity=27.5449101796407, Blast_Score=66, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17535357, Length=185, Percent_Identity=24.3243243243243, Blast_Score=66, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6325360, Length=189, Percent_Identity=30.6878306878307, Blast_Score=90, Evalue=3e-19,
Organism=Saccharomyces cerevisiae, GI6322459, Length=213, Percent_Identity=29.1079812206573, Blast_Score=87, Evalue=3e-18,
Organism=Saccharomyces cerevisiae, GI6324731, Length=200, Percent_Identity=32, Blast_Score=80, Evalue=4e-16,
Organism=Saccharomyces cerevisiae, GI6320849, Length=186, Percent_Identity=32.258064516129, Blast_Score=77, Evalue=3e-15,
Organism=Saccharomyces cerevisiae, GI6321574, Length=207, Percent_Identity=25.6038647342995, Blast_Score=62, Evalue=5e-11,
Organism=Drosophila melanogaster, GI20130281, Length=184, Percent_Identity=32.0652173913043, Blast_Score=104, Evalue=4e-23,
Organism=Drosophila melanogaster, GI21355573, Length=184, Percent_Identity=30.9782608695652, Blast_Score=92, Evalue=4e-19,
Organism=Drosophila melanogaster, GI24652553, Length=184, Percent_Identity=30.9782608695652, Blast_Score=92, Evalue=4e-19,
Organism=Drosophila melanogaster, GI24653999, Length=200, Percent_Identity=30, Blast_Score=88, Evalue=4e-18,
Organism=Drosophila melanogaster, GI24584895, Length=205, Percent_Identity=29.7560975609756, Blast_Score=83, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24639979, Length=197, Percent_Identity=29.4416243654822, Blast_Score=75, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24664391, Length=194, Percent_Identity=29.3814432989691, Blast_Score=75, Evalue=5e-14,
Organism=Drosophila melanogaster, GI24654391, Length=206, Percent_Identity=26.6990291262136, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24654389, Length=206, Percent_Identity=26.6990291262136, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24581176, Length=169, Percent_Identity=30.7692307692308, Blast_Score=66, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR019983
- InterPro:   IPR000243
- InterPro:   IPR016050
- InterPro:   IPR001353 [H]

Pfam domain/function: PF00227 Proteasome [H]

EC number: =3.4.25.1 [H]

Molecular weight: Translated: 24903; Mature: 24903

Theoretical pI: Translated: 9.05; Mature: 9.05

Prosite motif: PS00854 PROTEASOME_B

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNPKLTVTFLFLLLMVIMGNELQLENKILKGTTTVGIRVNDGVILAADRRASAGFFVANK
CCCCCHHHHHHHHHHHHHCCCEEECCCEECCCEEEEEEECCCEEEEECCCCCCCHHHHHH
MVRKVLYITDKIGITTAGSVADLQFIYDVLKNIYHYNSITKYGPISIKGIATRLANVLSA
HHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCEEHHHHHHHHHHHHHH
TKYFPYIVQILIGGYDDQPRLFNLDYLGDITEENYVATGSGSPVAMGVLEDEYNPKMTLD
HHHHHHHHHHHHCCCCCCCCEEEEHHCCCCCCCCEEEECCCCCEEEEEEECCCCCCCCHH
EAADLAKRAVFSAIKRDSFTGTGVIVAKIHSKGHEELEFYLNKKM
HHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCHHHHHHCCCCC
>Mature Secondary Structure
MNPKLTVTFLFLLLMVIMGNELQLENKILKGTTTVGIRVNDGVILAADRRASAGFFVANK
CCCCCHHHHHHHHHHHHHCCCEEECCCEECCCEEEEEEECCCEEEEECCCCCCCHHHHHH
MVRKVLYITDKIGITTAGSVADLQFIYDVLKNIYHYNSITKYGPISIKGIATRLANVLSA
HHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCEEHHHHHHHHHHHHHH
TKYFPYIVQILIGGYDDQPRLFNLDYLGDITEENYVATGSGSPVAMGVLEDEYNPKMTLD
HHHHHHHHHHHHCCCCCCCCEEEEHHCCCCCCCCEEEECCCCCEEEEEEECCCCCCCCHH
EAADLAKRAVFSAIKRDSFTGTGVIVAKIHSKGHEELEFYLNKKM
HHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA