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The map label for this gene is ywlC [H]

Identifier: 15897573

GI number: 15897573

Start: 572859

End: 573935

Strand: Reverse

Name: ywlC [H]

Synonym: SSO0664

Alternate gene names: 15897573

Gene position: 573935-572859 (Counterclockwise)

Preceding gene: 15897575

Following gene: 15897572

Centisome position: 19.18

GC content: 36.86

Gene sequence:

>1077_bases
ATGACTGAAGTACTTAAGGTCGATCCATTATATCCAGAATTAGATAAGATAAAAAAGGCTGCTAATGTAATAAAAGCCGG
CGGTACTGTAGTCTTTCCTACAGAAACTGTTTATGGATTAGGCGCAAACGCTCTAGATCCAGAAGCGGTGAAAAAGATAT
TCATCGCTAAAAATAGACCAATGGACAATCCTCTTATAGTTCATATATCAAATATAGATCAGCTTTATGAAGTAGCTAAA
GATATACCCAAAAAAATAATCAATTTAGTGAATATAGTGTGGCCCGGACCATTAACATTTGTCTTAAAGAAAACAGAGAA
AGTTCCTAAAGAGACCACCGGAGGGCTAGAAACTGTAGCAGTAAGAATGCCAGCTCATCCAGTTGCATTGGCTTTAATAA
ATGAAAGTGGCGTTCCAATAGCAGCGCCAAGTGCGAATTTGGCAACAAAACCTAGCCCTACTAGGGTAGAACATGTAATT
GATGACATATATGGAAAAGTAGATGTAATATTGGATTCTGGAGAAACGTTTTTTGGCGTCGAATCAACAGTTATAAACGT
TACAGTTGACCCTCCAGTACTTTTAAGGCCTGGTCCATTTAGTGTGGAAGAATTAGAAAGGTTATTTGGAAAGGTCGTTG
TTCCAGAACAAGCTAAAGGTACAGCGGAGTTTGACGTTGCATTAGCACCTGGCATGAAATATAAGCATTATGCTCCTACA
AAAAGGTTGCTAGTAGTTGAAAACAGAAGTGTACTACGTGGCGTCATCAACGAATTGCAAAAGAGAAGTTGTAGGATAGC
GCTTTTGTGCGCGAGTGAAGTTTGTAAGCAATTTCGAGGAGAAAAAATTGAAATAATAGAGCTCGGAAGTGAAAATAACC
TCTATGAGATATCTAGAAACTTATTTGATAGCTTTAGGAAGTTAGATAAATCTAATGTAGATATTGGAGTTATTCATAGT
ATTAGTGAGAAAGGAATAGGATTGGCAATAATGAATAGGACAAGAAAGGCATCCGGTTTCTCTTCAATTTATAATATAGA
AGATGTGTGGAAGTATGTTGGTAATAAGACTCAATAA

Upstream 100 bases:

>100_bases
AATAACTTTATTCAGAGATCACCTCAAAAATCATCAAATCATTTTTCTTGACTCATCATCGACAAGTATATTTTCTTGTT
AATCTTTAAAGTTAAAAATA

Downstream 100 bases:

>100_bases
GGTTACATCTACACAAGATTTCGCAGAAGCAATTAGCAATATGTTGTTTGAAGATTTTCTGGTAATCGCAGAGGAGCAAA
CTAAAGCTAGGGGAAGATTA

Product: hypothetical protein

Products: NA

Alternate protein names: t(6)A37 threonylcarbamoyladenosine biosynthesis protein YwlC [H]

Number of amino acids: Translated: 358; Mature: 357

Protein sequence:

>358_residues
MTEVLKVDPLYPELDKIKKAANVIKAGGTVVFPTETVYGLGANALDPEAVKKIFIAKNRPMDNPLIVHISNIDQLYEVAK
DIPKKIINLVNIVWPGPLTFVLKKTEKVPKETTGGLETVAVRMPAHPVALALINESGVPIAAPSANLATKPSPTRVEHVI
DDIYGKVDVILDSGETFFGVESTVINVTVDPPVLLRPGPFSVEELERLFGKVVVPEQAKGTAEFDVALAPGMKYKHYAPT
KRLLVVENRSVLRGVINELQKRSCRIALLCASEVCKQFRGEKIEIIELGSENNLYEISRNLFDSFRKLDKSNVDIGVIHS
ISEKGIGLAIMNRTRKASGFSSIYNIEDVWKYVGNKTQ

Sequences:

>Translated_358_residues
MTEVLKVDPLYPELDKIKKAANVIKAGGTVVFPTETVYGLGANALDPEAVKKIFIAKNRPMDNPLIVHISNIDQLYEVAK
DIPKKIINLVNIVWPGPLTFVLKKTEKVPKETTGGLETVAVRMPAHPVALALINESGVPIAAPSANLATKPSPTRVEHVI
DDIYGKVDVILDSGETFFGVESTVINVTVDPPVLLRPGPFSVEELERLFGKVVVPEQAKGTAEFDVALAPGMKYKHYAPT
KRLLVVENRSVLRGVINELQKRSCRIALLCASEVCKQFRGEKIEIIELGSENNLYEISRNLFDSFRKLDKSNVDIGVIHS
ISEKGIGLAIMNRTRKASGFSSIYNIEDVWKYVGNKTQ
>Mature_357_residues
TEVLKVDPLYPELDKIKKAANVIKAGGTVVFPTETVYGLGANALDPEAVKKIFIAKNRPMDNPLIVHISNIDQLYEVAKD
IPKKIINLVNIVWPGPLTFVLKKTEKVPKETTGGLETVAVRMPAHPVALALINESGVPIAAPSANLATKPSPTRVEHVID
DIYGKVDVILDSGETFFGVESTVINVTVDPPVLLRPGPFSVEELERLFGKVVVPEQAKGTAEFDVALAPGMKYKHYAPTK
RLLVVENRSVLRGVINELQKRSCRIALLCASEVCKQFRGEKIEIIELGSENNLYEISRNLFDSFRKLDKSNVDIGVIHSI
SEKGIGLAIMNRTRKASGFSSIYNIEDVWKYVGNKTQ

Specific function: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (Probable) [H]

COG id: COG0009

COG function: function code J; Putative translation factor (SUA5)

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 YrdC-like domain [H]

Homologues:

Organism=Homo sapiens, GI58761510, Length=195, Percent_Identity=26.6666666666667, Blast_Score=72, Evalue=5e-13,
Organism=Escherichia coli, GI2367210, Length=149, Percent_Identity=32.8859060402685, Blast_Score=85, Evalue=7e-18,
Organism=Escherichia coli, GI87081864, Length=203, Percent_Identity=27.5862068965517, Blast_Score=84, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17537239, Length=197, Percent_Identity=27.9187817258883, Blast_Score=83, Evalue=2e-16,
Organism=Saccharomyces cerevisiae, GI6321269, Length=409, Percent_Identity=38.8753056234719, Blast_Score=223, Evalue=5e-59,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017945
- InterPro:   IPR005145
- InterPro:   IPR004388
- InterPro:   IPR006070
- InterPro:   IPR010923 [H]

Pfam domain/function: PF03481 SUA5; PF01300 Sua5_yciO_yrdC [H]

EC number: NA

Molecular weight: Translated: 39394; Mature: 39263

Theoretical pI: Translated: 8.71; Mature: 8.71

Prosite motif: PS51163 YRDC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTEVLKVDPLYPELDKIKKAANVIKAGGTVVFPTETVYGLGANALDPEAVKKIFIAKNRP
CCCEEECCCCCCCHHHHHHHHHHHHCCCEEEECCCCEEECCCCCCCHHHHHHHHHCCCCC
MDNPLIVHISNIDQLYEVAKDIPKKIINLVNIVWPGPLTFVLKKTEKVPKETTGGLETVA
CCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEHHHHCCCCCCCCCEEEE
VRMPAHPVALALINESGVPIAAPSANLATKPSPTRVEHVIDDIYGKVDVILDSGETFFGV
EECCCCCEEEEEECCCCCEEECCCCCCCCCCCCHHHHHHHHHHCCEEEEEEECCCEEEEE
ESTVINVTVDPPVLLRPGPFSVEELERLFGKVVVPEQAKGTAEFDVALAPGMKYKHYAPT
EEEEEEEEECCCEEECCCCCCHHHHHHHHCCEECCCCCCCCCEEEEEECCCCCCCCCCCC
KRLLVVENRSVLRGVINELQKRSCRIALLCASEVCKQFRGEKIEIIELGSENNLYEISRN
CEEEEECCHHHHHHHHHHHHHCCCEEEEEEHHHHHHHHCCCEEEEEEECCCCCHHHHHHH
LFDSFRKLDKSNVDIGVIHSISEKGIGLAIMNRTRKASGFSSIYNIEDVWKYVGNKTQ
HHHHHHHHCCCCCCEEEEECCCCCCCEEEEECCCCCCCCHHHHCCHHHHHHHHCCCCC
>Mature Secondary Structure 
TEVLKVDPLYPELDKIKKAANVIKAGGTVVFPTETVYGLGANALDPEAVKKIFIAKNRP
CCEEECCCCCCCHHHHHHHHHHHHCCCEEEECCCCEEECCCCCCCHHHHHHHHHCCCCC
MDNPLIVHISNIDQLYEVAKDIPKKIINLVNIVWPGPLTFVLKKTEKVPKETTGGLETVA
CCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEHHHHCCCCCCCCCEEEE
VRMPAHPVALALINESGVPIAAPSANLATKPSPTRVEHVIDDIYGKVDVILDSGETFFGV
EECCCCCEEEEEECCCCCEEECCCCCCCCCCCCHHHHHHHHHHCCEEEEEEECCCEEEEE
ESTVINVTVDPPVLLRPGPFSVEELERLFGKVVVPEQAKGTAEFDVALAPGMKYKHYAPT
EEEEEEEEECCCEEECCCCCCHHHHHHHHCCEECCCCCCCCCEEEEEECCCCCCCCCCCC
KRLLVVENRSVLRGVINELQKRSCRIALLCASEVCKQFRGEKIEIIELGSENNLYEISRN
CEEEEECCHHHHHHHHHHHHHCCCEEEEEEHHHHHHHHCCCEEEEEEECCCCCHHHHHHH
LFDSFRKLDKSNVDIGVIHSISEKGIGLAIMNRTRKASGFSSIYNIEDVWKYVGNKTQ
HHHHHHHHCCCCCCEEEEECCCCCCCEEEEECCCCCCCCHHHHCCHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]