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The map label for this gene is atpI

Identifier: 15897481

GI number: 15897481

Start: 493405

End: 495510

Strand: Reverse

Name: atpI

Synonym: SSO0559

Alternate gene names: 15897481

Gene position: 495510-493405 (Counterclockwise)

Preceding gene: 15897494

Following gene: 15897479

Centisome position: 16.56

GC content: 35.42

Gene sequence:

>2106_bases
GTGCTATTGCCAGAGAATATGGTCAGATTACAGATAATTTCTGATAAATCAGCGATAGACCCTATTATAACTAAACTCCT
CAAGCTCGGCATGTTTCAACCAGAAGACCCCCTTTACCCATTAGGCAATGAAAGAATAGAAGATGCTAGAAGACTTATCA
CGGCAGTACAAGATCACGTAAGTAAATTAAAAATAATCATGGAATTAGGAGGATTAGTAATAGAACCATTGGGGAGCATC
AAAGTAAGTAGTTGGATCAAGGCTGCACAAGATGTCAGTGAAGAGGCGTCGAAATTAGAAGAAAGGTACAAGGAACTATT
AGAGGAAATAGGCAGACTGAGATCAGAGAAAGATCTTTATCAGCAACAGTTAAAAGAGCTAGAACCGATTAAGTCAATAA
CTGTAGAATTATCCAAACTATATTCTTTGGAACTATTTGACGTAATATTAGCTCAAGTTGATGAGGACAAGTTAAGGCTT
ATCAACCAAATTATAGGTGATTCCAACTTCGTGTATTATACGAGGTTTGGAGAGGAAAGGTATATTGTTCTAATCATCGC
CGAGAAGAATATTAATGTAGATAAGAAATTGAGAGAAGCTGGGGTTAGGAGATATGAGCTACAAGAAGGAAAATCCCCTT
TTCAGCTCTATAACGAAATTTTAGAAAGAATAAATCAAATAAACATTATTTTAGAAAGAACTAGAGAAGAATTAGCAAAG
AAAGTGAAGACTGAGGAGAACTATATTAAAAATGTATACGGTAAATTACTGACTGTTCGTGATGCGCTAAATATCATGAA
TAAAGCTAGAGTCTCTGAATACTATTTGCAAATAGAAGGTTATTTTCCTGAAAAACATGTTAAAAAAGTACAGAATGAGA
TTAATAATTTAGCATTTATGGATTATATAAGGCCTAGGAGATATGGTGAAAAAGAGGAACCACCGACATTAGTTGAATTA
CCAAAGTCCATAAAGGTTTTAGAATCCTTAGTCGAAATATATGGCTCACCATCCTATTGGGAAATATCACCTATAGTCTT
CCTTGTTTTTACTTTCCCAATACTATTTGGTTTAATGTTCCCCGATTTTGGGAACGCCTTAGTTTTATTGCTATTCTCAA
TATGGTTTTACAGATATGGGAAGAAGAGAGGAAGTGAAAATATTCCTAAATTATCCATAATTCTAATATACTCAAGTATA
GTTGCAATCATAACGGGTTTACTAGCTAGAGATTTCTTTGGTCCATTACCAGTAGGTGGATTAAGGGAGATATTAAATAA
TGGGAACTATAGCGCAGGGCCTCTTTACAACTTATGGCCAATCCCAGCAAGTGTATCCGAGGCAATAAAGTTTCTCTTAC
CATTCGGAGAGTACAGTACTAGTGTTAGTATAGAAAATACTATGATATTTTCAGTATTACTGGGAGCCCTAGCGCTATTT
GTGAGCTCCTTATTAGGTGTTATAGATGCAATTAGAAAGAAGGATCCAGAATTCTTGTTCTTGGAGAAACTCCCACTATT
CTTACTGTACGTAGTTCCAATATTTATCTTCATGTATGGTATAACCGATCCAGCCAATTTCTTTACCGTAGATCAACAGA
TATTAGGCCAAATACTTAACGCCGTTCTTATGAAATCCTTTAGTGAAAATATTGTAGGTTACGGAATAGTTTGGTGGACT
TCGTTTGCACTATTATATAATTGGGCTGCTCACGCAATTTTAGTTAAAAGGCATGATAATGCTACGTGGGGTTCTGCGAT
TGCTATGGGGTTCATAGAAGGTGGATTTGAGGGAGCCCTACTATTATTGTCTAATACTATTTCATTTATAAGAGTCTTAG
TATTCGCTTTATCACACTATTATATACTATATGCATTCTCTTATATGGCCTACTTAGTTGCACCATCCACAACTACTATA
GGAGTCCTAATAAACCCCATAGCAATTATCATATTGATTATAGGGAACTTGTTAGCTATAGGCTTAGAAGGGTTAGTAGT
ATTTATACAAGATTTAAGGCTTCATTTCTACGAGATGTTCAGTAAGTTCTATGAAGGAAGAGGAAGAAAATTCGAGCCGG
TTATGGCTTACGTCTCACTTGAGTAA

Upstream 100 bases:

>100_bases
TCTCCAACTACAAACACTTTACCCATTGCGAATTAATTCTAAATAACAGAGATTAAATACTTATAAGTGACCTACTAATA
CATATCCCGAGGTAATTGAA

Downstream 100 bases:

>100_bases
GGTAGGTCTTATTTTTTCTATATCTTTCCTTATTTTTTCCAGTTTATCCTTTATCTTAGACTCAAATTCTGGTTCAAGTT
TCTTGAAAAGTACATTAACT

Product: V-type ATP synthase subunit I

Products: ADP; phosphate; H+

Alternate protein names: V-ATPase subunit I

Number of amino acids: Translated: 701; Mature: 701

Protein sequence:

>701_residues
MLLPENMVRLQIISDKSAIDPIITKLLKLGMFQPEDPLYPLGNERIEDARRLITAVQDHVSKLKIIMELGGLVIEPLGSI
KVSSWIKAAQDVSEEASKLEERYKELLEEIGRLRSEKDLYQQQLKELEPIKSITVELSKLYSLELFDVILAQVDEDKLRL
INQIIGDSNFVYYTRFGEERYIVLIIAEKNINVDKKLREAGVRRYELQEGKSPFQLYNEILERINQINIILERTREELAK
KVKTEENYIKNVYGKLLTVRDALNIMNKARVSEYYLQIEGYFPEKHVKKVQNEINNLAFMDYIRPRRYGEKEEPPTLVEL
PKSIKVLESLVEIYGSPSYWEISPIVFLVFTFPILFGLMFPDFGNALVLLLFSIWFYRYGKKRGSENIPKLSIILIYSSI
VAIITGLLARDFFGPLPVGGLREILNNGNYSAGPLYNLWPIPASVSEAIKFLLPFGEYSTSVSIENTMIFSVLLGALALF
VSSLLGVIDAIRKKDPEFLFLEKLPLFLLYVVPIFIFMYGITDPANFFTVDQQILGQILNAVLMKSFSENIVGYGIVWWT
SFALLYNWAAHAILVKRHDNATWGSAIAMGFIEGGFEGALLLLSNTISFIRVLVFALSHYYILYAFSYMAYLVAPSTTTI
GVLINPIAIIILIIGNLLAIGLEGLVVFIQDLRLHFYEMFSKFYEGRGRKFEPVMAYVSLE

Sequences:

>Translated_701_residues
MLLPENMVRLQIISDKSAIDPIITKLLKLGMFQPEDPLYPLGNERIEDARRLITAVQDHVSKLKIIMELGGLVIEPLGSI
KVSSWIKAAQDVSEEASKLEERYKELLEEIGRLRSEKDLYQQQLKELEPIKSITVELSKLYSLELFDVILAQVDEDKLRL
INQIIGDSNFVYYTRFGEERYIVLIIAEKNINVDKKLREAGVRRYELQEGKSPFQLYNEILERINQINIILERTREELAK
KVKTEENYIKNVYGKLLTVRDALNIMNKARVSEYYLQIEGYFPEKHVKKVQNEINNLAFMDYIRPRRYGEKEEPPTLVEL
PKSIKVLESLVEIYGSPSYWEISPIVFLVFTFPILFGLMFPDFGNALVLLLFSIWFYRYGKKRGSENIPKLSIILIYSSI
VAIITGLLARDFFGPLPVGGLREILNNGNYSAGPLYNLWPIPASVSEAIKFLLPFGEYSTSVSIENTMIFSVLLGALALF
VSSLLGVIDAIRKKDPEFLFLEKLPLFLLYVVPIFIFMYGITDPANFFTVDQQILGQILNAVLMKSFSENIVGYGIVWWT
SFALLYNWAAHAILVKRHDNATWGSAIAMGFIEGGFEGALLLLSNTISFIRVLVFALSHYYILYAFSYMAYLVAPSTTTI
GVLINPIAIIILIIGNLLAIGLEGLVVFIQDLRLHFYEMFSKFYEGRGRKFEPVMAYVSLE
>Mature_701_residues
MLLPENMVRLQIISDKSAIDPIITKLLKLGMFQPEDPLYPLGNERIEDARRLITAVQDHVSKLKIIMELGGLVIEPLGSI
KVSSWIKAAQDVSEEASKLEERYKELLEEIGRLRSEKDLYQQQLKELEPIKSITVELSKLYSLELFDVILAQVDEDKLRL
INQIIGDSNFVYYTRFGEERYIVLIIAEKNINVDKKLREAGVRRYELQEGKSPFQLYNEILERINQINIILERTREELAK
KVKTEENYIKNVYGKLLTVRDALNIMNKARVSEYYLQIEGYFPEKHVKKVQNEINNLAFMDYIRPRRYGEKEEPPTLVEL
PKSIKVLESLVEIYGSPSYWEISPIVFLVFTFPILFGLMFPDFGNALVLLLFSIWFYRYGKKRGSENIPKLSIILIYSSI
VAIITGLLARDFFGPLPVGGLREILNNGNYSAGPLYNLWPIPASVSEAIKFLLPFGEYSTSVSIENTMIFSVLLGALALF
VSSLLGVIDAIRKKDPEFLFLEKLPLFLLYVVPIFIFMYGITDPANFFTVDQQILGQILNAVLMKSFSENIVGYGIVWWT
SFALLYNWAAHAILVKRHDNATWGSAIAMGFIEGGFEGALLLLSNTISFIRVLVFALSHYYILYAFSYMAYLVAPSTTTI
GVLINPIAIIILIIGNLLAIGLEGLVVFIQDLRLHFYEMFSKFYEGRGRKFEPVMAYVSLE

Specific function: Produces ATP from ADP in the presence of a proton gradient across the membrane

COG id: COG1269

COG function: function code C; Archaeal/vacuolar-type H+-ATPase subunit I

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential)

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the V-ATPase 116 kDa subunit family

Homologues:

Organism=Homo sapiens, GI42741679, Length=238, Percent_Identity=25.6302521008403, Blast_Score=70, Evalue=8e-12,
Organism=Caenorhabditis elegans, GI17542706, Length=186, Percent_Identity=26.8817204301075, Blast_Score=73, Evalue=6e-13,
Organism=Drosophila melanogaster, GI24647955, Length=338, Percent_Identity=24.2603550295858, Blast_Score=79, Evalue=2e-14,
Organism=Drosophila melanogaster, GI21357019, Length=338, Percent_Identity=24.2603550295858, Blast_Score=79, Evalue=2e-14,
Organism=Drosophila melanogaster, GI21357061, Length=228, Percent_Identity=28.9473684210526, Blast_Score=73, Evalue=7e-13,
Organism=Drosophila melanogaster, GI24583722, Length=312, Percent_Identity=24.3589743589744, Blast_Score=71, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24650967, Length=230, Percent_Identity=24.3478260869565, Blast_Score=70, Evalue=4e-12,
Organism=Drosophila melanogaster, GI24650965, Length=230, Percent_Identity=24.3478260869565, Blast_Score=70, Evalue=4e-12,
Organism=Drosophila melanogaster, GI24650959, Length=230, Percent_Identity=24.3478260869565, Blast_Score=70, Evalue=4e-12,
Organism=Drosophila melanogaster, GI24650961, Length=230, Percent_Identity=24.3478260869565, Blast_Score=70, Evalue=4e-12,
Organism=Drosophila melanogaster, GI45551995, Length=230, Percent_Identity=24.3478260869565, Blast_Score=70, Evalue=4e-12,
Organism=Drosophila melanogaster, GI24650963, Length=230, Percent_Identity=24.3478260869565, Blast_Score=70, Evalue=4e-12,
Organism=Drosophila melanogaster, GI281362794, Length=230, Percent_Identity=24.3478260869565, Blast_Score=70, Evalue=4e-12,
Organism=Drosophila melanogaster, GI281362792, Length=230, Percent_Identity=24.3478260869565, Blast_Score=70, Evalue=4e-12,
Organism=Drosophila melanogaster, GI21358171, Length=230, Percent_Identity=24.3478260869565, Blast_Score=70, Evalue=5e-12,
Organism=Drosophila melanogaster, GI24650956, Length=230, Percent_Identity=24.3478260869565, Blast_Score=70, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): VATI_SULSO (Q9UWW3)

Other databases:

- EMBL:   Y18930
- EMBL:   AE006641
- PIR:   E90202
- RefSeq:   NP_342086.1
- ProteinModelPortal:   Q9UWW3
- GeneID:   1454843
- GenomeReviews:   AE006641_GR
- KEGG:   sso:SSO0559
- NMPDR:   fig|273057.1.peg.509
- HOGENOM:   HBG553426
- OMA:   LLETMTN
- ProtClustDB:   PRK05771
- BioCyc:   SSOL273057:SSO0559-MONOMER
- BRENDA:   3.6.3.14
- InterPro:   IPR002490
- PANTHER:   PTHR11629

Pfam domain/function: PF01496 V_ATPase_I

EC number: 3.6.3.14

Molecular weight: Translated: 80133; Mature: 80133

Theoretical pI: Translated: 5.53; Mature: 5.53

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0xcba54b4)-; HASH(0xc8d8a48)-; HASH(0xd36d7bc)-; HASH(0xcceba14)-; HASH(0xd13236c)-; HASH(0xb1d3850)-; HASH(0xc8f50b8)-; HASH(0xcef4db8)-; HASH(0xc8db7b4)-; HASH(0xd1fdb44)-;

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLLPENMVRLQIISDKSAIDPIITKLLKLGMFQPEDPLYPLGNERIEDARRLITAVQDHV
CCCCCCCEEEEEECCCHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHH
SKLKIIMELGGLVIEPLGSIKVSSWIKAAQDVSEEASKLEERYKELLEEIGRLRSEKDLY
HHHHHHHHHCCHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHH
QQQLKELEPIKSITVELSKLYSLELFDVILAQVDEDKLRLINQIIGDSNFVYYTRFGEER
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCEEEEEEECCCE
YIVLIIAEKNINVDKKLREAGVRRYELQEGKSPFQLYNEILERINQINIILERTREELAK
EEEEEEECCCCCHHHHHHHCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KVKTEENYIKNVYGKLLTVRDALNIMNKARVSEYYLQIEGYFPEKHVKKVQNEINNLAFM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCHHHHHHHHHHHHHHHHH
DYIRPRRYGEKEEPPTLVELPKSIKVLESLVEIYGSPSYWEISPIVFLVFTFPILFGLMF
HHHHHHCCCCCCCCCHHHHCCHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHHHC
PDFGNALVLLLFSIWFYRYGKKRGSENIPKLSIILIYSSIVAIITGLLARDFFGPLPVGG
CCCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHH
LREILNNGNYSAGPLYNLWPIPASVSEAIKFLLPFGEYSTSVSIENTMIFSVLLGALALF
HHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCEEHHHHHHHHHHHHHHHHH
VSSLLGVIDAIRKKDPEFLFLEKLPLFLLYVVPIFIFMYGITDPANFFTVDQQILGQILN
HHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
AVLMKSFSENIVGYGIVWWTSFALLYNWAAHAILVKRHDNATWGSAIAMGFIEGGFEGAL
HHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCHHHHHHHHHHHCCCCHHH
LLLSNTISFIRVLVFALSHYYILYAFSYMAYLVAPSTTTIGVLINPIAIIILIIGNLLAI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHH
GLEGLVVFIQDLRLHFYEMFSKFYEGRGRKFEPVMAYVSLE
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECH
>Mature Secondary Structure
MLLPENMVRLQIISDKSAIDPIITKLLKLGMFQPEDPLYPLGNERIEDARRLITAVQDHV
CCCCCCCEEEEEECCCHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHH
SKLKIIMELGGLVIEPLGSIKVSSWIKAAQDVSEEASKLEERYKELLEEIGRLRSEKDLY
HHHHHHHHHCCHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHH
QQQLKELEPIKSITVELSKLYSLELFDVILAQVDEDKLRLINQIIGDSNFVYYTRFGEER
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCEEEEEEECCCE
YIVLIIAEKNINVDKKLREAGVRRYELQEGKSPFQLYNEILERINQINIILERTREELAK
EEEEEEECCCCCHHHHHHHCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KVKTEENYIKNVYGKLLTVRDALNIMNKARVSEYYLQIEGYFPEKHVKKVQNEINNLAFM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCHHHHHHHHHHHHHHHHH
DYIRPRRYGEKEEPPTLVELPKSIKVLESLVEIYGSPSYWEISPIVFLVFTFPILFGLMF
HHHHHHCCCCCCCCCHHHHCCHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHHHC
PDFGNALVLLLFSIWFYRYGKKRGSENIPKLSIILIYSSIVAIITGLLARDFFGPLPVGG
CCCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHH
LREILNNGNYSAGPLYNLWPIPASVSEAIKFLLPFGEYSTSVSIENTMIFSVLLGALALF
HHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCEEHHHHHHHHHHHHHHHHH
VSSLLGVIDAIRKKDPEFLFLEKLPLFLLYVVPIFIFMYGITDPANFFTVDQQILGQILN
HHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
AVLMKSFSENIVGYGIVWWTSFALLYNWAAHAILVKRHDNATWGSAIAMGFIEGGFEGAL
HHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCHHHHHHHHHHHCCCCHHH
LLLSNTISFIRVLVFALSHYYILYAFSYMAYLVAPSTTTIGVLINPIAIIILIIGNLLAI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHH
GLEGLVVFIQDLRLHFYEMFSKFYEGRGRKFEPVMAYVSLE
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; H2O; H+

Specific reaction: ATP + H2O + H+(in) = ADP + phosphate + H+(out)

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10701121; 11427726