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The map label for this gene is tkt-1 [C]

Identifier: 15897243

GI number: 15897243

Start: 255258

End: 256103

Strand: Direct

Name: tkt-1 [C]

Synonym: SSO0297

Alternate gene names: 15897243

Gene position: 255258-256103 (Clockwise)

Preceding gene: 15897225

Following gene: 15897244

Centisome position: 8.53

GC content: 38.65

Gene sequence:

>846_bases
GTGGGGATTGATATTGTTCCAATGGAAAAAGGTGGAGGGAGTGATGGAACTCCAATATCAATAGAGGAATTGGACAAGTT
AAGACAAGTAGCTGAAAAGGCAAGAAGAAATGTAATAAAAATGCTATTTTATGATCAAACAATACATGTGGGATCGTCCC
TAAGTAGCATAGAGATATTAACTACGTTAATATTCAAGCATATAAGGACGGATTCAAGCTTAGTGAATAAAGACTGGCTT
ATTTTAAGTAAAGGCCATGCAGCGCCAGCTCTTTATGCCGTTTTAGCTGAAAAAGGTTACATAAAAGAAGAGGAACTTTG
GAGAATACAAGATATAACGGGATTATTACAAGGGCATCCAGAAACTTTTATTCCCGGTGTAGATATGTCGACTGGTAGTT
TAGGGCAAGGTTTGAGCTTTGGAATAGGTGTTGCTACTGGTATAAAGATGGCCAACGGCACTGGAAGAGTATATGTCATA
ATGGGTGATGGTGAACAGGATGAGGGAGAAATATGGGAGGCTATGACGCATGCAGTAGTTAGAAATCTTGATAACTTAAT
TGCATTTATAGAGATGAACAATTTCCAGCTTGATGGTTCAACAGATGAGATAAAACCAAAGAACTTCTTACCTAAGGTAT
GGGAAGCAGTAGGTTGGAAAGTATTAAACTGCGATGGGCATGATTTCATTAGTATTACTAATGCAGTTAACGAGGCATAT
AAGGCAAGCAAGCCCGTAGTAATATTCGCTAAGACTGTAAGAGGAAAGGGGTTTCCTCCAATAGAAAATACCCATAAACA
GAGGTCCAGTCCAGATGATGCAAGGAAATATTTACTCAATGCGTGA

Upstream 100 bases:

>100_bases
CTGTTGAATTCCTAATCCTAAAACTATTAGTTGCCTAGAATATCTTTCCACAAGATTATAATGTAGAATAATCTTTAAAA
ATAAGTGTTGCCTACTAAAA

Downstream 100 bases:

>100_bases
AACCTTCGGAAGGCTATTAGCAGACCTAGGGGATAAGAACAAGGATCTAGTCGTGATAACTGCAGATGTAGGAGACTCTA
CCAGAGCGCTATACTTTAGA

Product: transketolase, N-terminal section (tkt-1)

Products: NA

Alternate protein names: TK [H]

Number of amino acids: Translated: 281; Mature: 280

Protein sequence:

>281_residues
MGIDIVPMEKGGGSDGTPISIEELDKLRQVAEKARRNVIKMLFYDQTIHVGSSLSSIEILTTLIFKHIRTDSSLVNKDWL
ILSKGHAAPALYAVLAEKGYIKEEELWRIQDITGLLQGHPETFIPGVDMSTGSLGQGLSFGIGVATGIKMANGTGRVYVI
MGDGEQDEGEIWEAMTHAVVRNLDNLIAFIEMNNFQLDGSTDEIKPKNFLPKVWEAVGWKVLNCDGHDFISITNAVNEAY
KASKPVVIFAKTVRGKGFPPIENTHKQRSSPDDARKYLLNA

Sequences:

>Translated_281_residues
MGIDIVPMEKGGGSDGTPISIEELDKLRQVAEKARRNVIKMLFYDQTIHVGSSLSSIEILTTLIFKHIRTDSSLVNKDWL
ILSKGHAAPALYAVLAEKGYIKEEELWRIQDITGLLQGHPETFIPGVDMSTGSLGQGLSFGIGVATGIKMANGTGRVYVI
MGDGEQDEGEIWEAMTHAVVRNLDNLIAFIEMNNFQLDGSTDEIKPKNFLPKVWEAVGWKVLNCDGHDFISITNAVNEAY
KASKPVVIFAKTVRGKGFPPIENTHKQRSSPDDARKYLLNA
>Mature_280_residues
GIDIVPMEKGGGSDGTPISIEELDKLRQVAEKARRNVIKMLFYDQTIHVGSSLSSIEILTTLIFKHIRTDSSLVNKDWLI
LSKGHAAPALYAVLAEKGYIKEEELWRIQDITGLLQGHPETFIPGVDMSTGSLGQGLSFGIGVATGIKMANGTGRVYVIM
GDGEQDEGEIWEAMTHAVVRNLDNLIAFIEMNNFQLDGSTDEIKPKNFLPKVWEAVGWKVLNCDGHDFISITNAVNEAYK
ASKPVVIFAKTVRGKGFPPIENTHKQRSSPDDARKYLLNA

Specific function: Unknown

COG id: COG3959

COG function: function code G; Transketolase, N-terminal subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transketolase family [H]

Homologues:

Organism=Homo sapiens, GI133778974, Length=264, Percent_Identity=35.2272727272727, Blast_Score=157, Evalue=8e-39,
Organism=Homo sapiens, GI205277463, Length=254, Percent_Identity=35.4330708661417, Blast_Score=152, Evalue=4e-37,
Organism=Homo sapiens, GI4507521, Length=254, Percent_Identity=35.4330708661417, Blast_Score=152, Evalue=4e-37,
Organism=Homo sapiens, GI225637463, Length=147, Percent_Identity=36.0544217687075, Blast_Score=97, Evalue=2e-20,
Organism=Homo sapiens, GI225637459, Length=147, Percent_Identity=36.0544217687075, Blast_Score=97, Evalue=2e-20,
Organism=Homo sapiens, GI225637461, Length=147, Percent_Identity=36.0544217687075, Blast_Score=97, Evalue=2e-20,
Organism=Escherichia coli, GI48994911, Length=268, Percent_Identity=31.7164179104478, Blast_Score=102, Evalue=3e-23,
Organism=Escherichia coli, GI1788808, Length=252, Percent_Identity=32.5396825396825, Blast_Score=100, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI17539652, Length=250, Percent_Identity=33.2, Blast_Score=141, Evalue=4e-34,
Organism=Saccharomyces cerevisiae, GI6319593, Length=231, Percent_Identity=32.034632034632, Blast_Score=94, Evalue=2e-20,
Organism=Saccharomyces cerevisiae, GI6325331, Length=202, Percent_Identity=34.1584158415842, Blast_Score=94, Evalue=3e-20,
Organism=Drosophila melanogaster, GI24666278, Length=259, Percent_Identity=38.2239382239382, Blast_Score=144, Evalue=6e-35,
Organism=Drosophila melanogaster, GI45551847, Length=254, Percent_Identity=35.8267716535433, Blast_Score=137, Evalue=1e-32,
Organism=Drosophila melanogaster, GI45550715, Length=254, Percent_Identity=35.8267716535433, Blast_Score=137, Evalue=1e-32,
Organism=Drosophila melanogaster, GI24645119, Length=211, Percent_Identity=37.914691943128, Blast_Score=127, Evalue=9e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005474 [H]

Pfam domain/function: PF00456 Transketolase_N [H]

EC number: =2.2.1.1 [H]

Molecular weight: Translated: 30941; Mature: 30810

Theoretical pI: Translated: 5.91; Mature: 5.91

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGIDIVPMEKGGGSDGTPISIEELDKLRQVAEKARRNVIKMLFYDQTIHVGSSLSSIEIL
CCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCEEECCCCCHHHHHH
TTLIFKHIRTDSSLVNKDWLILSKGHAAPALYAVLAEKGYIKEEELWRIQDITGLLQGHP
HHHHHHHHCCCCHHCCCCEEEEECCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCC
ETFIPGVDMSTGSLGQGLSFGIGVATGIKMANGTGRVYVIMGDGEQDEGEIWEAMTHAVV
CCCCCCCCCCCCCCCCCCHHHHHHHHCEEEECCCCEEEEEECCCCCCHHHHHHHHHHHHH
RNLDNLIAFIEMNNFQLDGSTDEIKPKNFLPKVWEAVGWKVLNCDGHDFISITNAVNEAY
HHHHHEEEEEEECCEEECCCCCCCCCCHHHHHHHHHHCCEEEECCCCCHHHHHHHHHHHH
KASKPVVIFAKTVRGKGFPPIENTHKQRSSPDDARKYLLNA
HCCCCEEEEEEECCCCCCCCCCCHHHHCCCHHHHHHHHCCC
>Mature Secondary Structure 
GIDIVPMEKGGGSDGTPISIEELDKLRQVAEKARRNVIKMLFYDQTIHVGSSLSSIEIL
CCEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCEEECCCCCHHHHHH
TTLIFKHIRTDSSLVNKDWLILSKGHAAPALYAVLAEKGYIKEEELWRIQDITGLLQGHP
HHHHHHHHCCCCHHCCCCEEEEECCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCC
ETFIPGVDMSTGSLGQGLSFGIGVATGIKMANGTGRVYVIMGDGEQDEGEIWEAMTHAVV
CCCCCCCCCCCCCCCCCCHHHHHHHHCEEEECCCCEEEEEECCCCCCHHHHHHHHHHHHH
RNLDNLIAFIEMNNFQLDGSTDEIKPKNFLPKVWEAVGWKVLNCDGHDFISITNAVNEAY
HHHHHEEEEEEECCEEECCCCCCCCCCHHHHHHHHHHCCEEEECCCCCHHHHHHHHHHHH
KASKPVVIFAKTVRGKGFPPIENTHKQRSSPDDARKYLLNA
HCCCCEEEEEEECCCCCCCCCCCHHHHCCCHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]