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The map label for this gene is purP [H]

Identifier: 15897187

GI number: 15897187

Start: 208923

End: 209972

Strand: Direct

Name: purP [H]

Synonym: SSO0241

Alternate gene names: 15897187

Gene position: 208923-209972 (Clockwise)

Preceding gene: 15897186

Following gene: 15897188

Centisome position: 6.98

GC content: 34.38

Gene sequence:

>1050_bases
ATGAATGTTAAGATAGCTGCATTAGCTAGTCATTCTGCACTTGACGTCTTCGATGGAGCTAAAGATGAAGGTTTTCAAAC
AATAGGGCTGTGTAAAAAGGGAAGAGAAAGACCTTATTTGGAATTTAAAGCAATCATGGATAAATGCATAATTTTGGAAG
ATTTCAAAGAAATAATCTCAGATAAGGTACAAAGTATACTACTCAGCGAAAATGCCATAATTGTTCCTAATAGGAGCTTA
GCGGTTTATGTAGGTTATGATGGAATAGAAAAAATGAAAACGAAAGTCTTCGGCAATAGATATATGTTACGATGGGAAGA
AAGGATAGGTGAGAAAAATTATTATAAAATACTAAATGAGGCGAAGATCTCTATACCCAAATTATTCAAACCAGAAGAGA
TTGATAGACCAGTAATAGTTAAACTACCTGAGGCCAAAAGGAAAGTTGAGAGAGGATTCTTTTTCGCTGTAAACAAGGAA
GATTTCGAAGCTAAACTCAACGAATTATTGAGAAATAACGTAATAGATAATGAAGGTTTAAAAAATATGGTAATAGAGGA
ATTTGTGTTTGGAGCTCACTTTAATCTTAACTACTTCTACAGCCCAATATTTAATAGATTAGAATTAATAAGCGTGGATA
GAAGAATTCAAAGTGACTGGGATAGCTTATATAGATTGCCTGCTGACATTCAAATAAAATTAGGTAGGATACCAAAACTA
ATAGAGGTTGGCCATGAGCCAGTAACAATAAGAGAAAGCTTGTTGGAAAAAGTCTTTGAGATAGGATATAGGTTTGTAGA
CGCCACACAAAAACTTGAGCCCCCTGGGATAATAGGACCCTTTACTCTACAAGTTATGGTGACCCCAGATTTGGATCTTG
TCGTATACGATGTTGCCCCAAGAATTGGAGGTGGTACAAATGTATATATGGGAACTGGGAGTCAATACTCTAAATTTTAC
TTCGGAAAGCCAATAAGTTTAGGAAGAAGAATAGCATTAGAGATAAAGCATGCTATAATAAATAATCTTACCGAAAAAAT
ACTAACTTAA

Upstream 100 bases:

>100_bases
TTGGCTTTACTGGGATGAGCCCATGAGTATAGGAAGAAGGATCGCAAGAGAAATCAGAGTCGCAAACGAAAAAGATAAGT
TAAGCCTCGTGGTGAGCTAA

Downstream 100 bases:

>100_bases
TATGTCATTATGATTTTTACGTTAATTAAGAAGATGTTATCGAAGTATCTAGGTTTCTATAATGACAGATAAGGCATAGA
TATACTTAAATAAGATAAAG

Product: 5-formaminoimidazole-4-carboxamide-1-(beta)-D- ribofuranosyl 5'-monophosphate synthetase-like protein

Products: NA

Alternate protein names: 5-aminoimidazole-4-carboxamide-1-beta-D-ribofuranosyl 5'-monophosphate--formate ligase [H]

Number of amino acids: Translated: 349; Mature: 349

Protein sequence:

>349_residues
MNVKIAALASHSALDVFDGAKDEGFQTIGLCKKGRERPYLEFKAIMDKCIILEDFKEIISDKVQSILLSENAIIVPNRSL
AVYVGYDGIEKMKTKVFGNRYMLRWEERIGEKNYYKILNEAKISIPKLFKPEEIDRPVIVKLPEAKRKVERGFFFAVNKE
DFEAKLNELLRNNVIDNEGLKNMVIEEFVFGAHFNLNYFYSPIFNRLELISVDRRIQSDWDSLYRLPADIQIKLGRIPKL
IEVGHEPVTIRESLLEKVFEIGYRFVDATQKLEPPGIIGPFTLQVMVTPDLDLVVYDVAPRIGGGTNVYMGTGSQYSKFY
FGKPISLGRRIALEIKHAIINNLTEKILT

Sequences:

>Translated_349_residues
MNVKIAALASHSALDVFDGAKDEGFQTIGLCKKGRERPYLEFKAIMDKCIILEDFKEIISDKVQSILLSENAIIVPNRSL
AVYVGYDGIEKMKTKVFGNRYMLRWEERIGEKNYYKILNEAKISIPKLFKPEEIDRPVIVKLPEAKRKVERGFFFAVNKE
DFEAKLNELLRNNVIDNEGLKNMVIEEFVFGAHFNLNYFYSPIFNRLELISVDRRIQSDWDSLYRLPADIQIKLGRIPKL
IEVGHEPVTIRESLLEKVFEIGYRFVDATQKLEPPGIIGPFTLQVMVTPDLDLVVYDVAPRIGGGTNVYMGTGSQYSKFY
FGKPISLGRRIALEIKHAIINNLTEKILT
>Mature_349_residues
MNVKIAALASHSALDVFDGAKDEGFQTIGLCKKGRERPYLEFKAIMDKCIILEDFKEIISDKVQSILLSENAIIVPNRSL
AVYVGYDGIEKMKTKVFGNRYMLRWEERIGEKNYYKILNEAKISIPKLFKPEEIDRPVIVKLPEAKRKVERGFFFAVNKE
DFEAKLNELLRNNVIDNEGLKNMVIEEFVFGAHFNLNYFYSPIFNRLELISVDRRIQSDWDSLYRLPADIQIKLGRIPKL
IEVGHEPVTIRESLLEKVFEIGYRFVDATQKLEPPGIIGPFTLQVMVTPDLDLVVYDVAPRIGGGTNVYMGTGSQYSKFY
FGKPISLGRRIALEIKHAIINNLTEKILT

Specific function: Catalyzes the ATP- and formate-dependent formylation of 5-aminoimidazole-4-carboxamide-1-beta-d-ribofuranosyl 5'- monophosphate (AICAR) to 5-formaminoimidazole-4-carboxamide-1- beta-d-ribofuranosyl 5'-monophosphate (FAICAR) in the absence of folates [H]

COG id: COG1759

COG function: function code R; ATP-utilizing enzymes of ATP-grasp superfamily (probably carboligases)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ATP-grasp domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011761
- InterPro:   IPR013815
- InterPro:   IPR013816
- InterPro:   IPR009720
- InterPro:   IPR010672
- InterPro:   IPR013817 [H]

Pfam domain/function: PF06849 DUF1246; PF06973 DUF1297 [H]

EC number: NA

Molecular weight: Translated: 40019; Mature: 40019

Theoretical pI: Translated: 8.54; Mature: 8.54

Prosite motif: PS50975 ATP_GRASP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNVKIAALASHSALDVFDGAKDEGFQTIGLCKKGRERPYLEFKAIMDKCIILEDFKEIIS
CCEEEEEECCCCCHHHCCCCCCCCCEEHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHH
DKVQSILLSENAIIVPNRSLAVYVGYDGIEKMKTKVFGNRYMLRWEERIGEKNYYKILNE
HHHHHHHHCCCEEEECCCCEEEEECCCCHHHHHHHHCCCCEEEEEHHHCCCCHHHHHHHH
AKISIPKLFKPEEIDRPVIVKLPEAKRKVERGFFFAVNKEDFEAKLNELLRNNVIDNEGL
HHCCCCCCCCCCCCCCCEEEECCHHHHHHHCCEEEEECCHHHHHHHHHHHHHCCCCCCCH
KNMVIEEFVFGAHFNLNYFYSPIFNRLELISVDRRIQSDWDSLYRLPADIQIKLGRIPKL
HHHHHHHHHHCCEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCHH
IEVGHEPVTIRESLLEKVFEIGYRFVDATQKLEPPGIIGPFTLQVMVTPDLDLVVYDVAP
HHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEECCCCCEEEEECCC
RIGGGTNVYMGTGSQYSKFYFGKPISLGRRIALEIKHAIINNLTEKILT
CCCCCCEEEEECCCCCCCEECCCCHHHCCCHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNVKIAALASHSALDVFDGAKDEGFQTIGLCKKGRERPYLEFKAIMDKCIILEDFKEIIS
CCEEEEEECCCCCHHHCCCCCCCCCEEHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHH
DKVQSILLSENAIIVPNRSLAVYVGYDGIEKMKTKVFGNRYMLRWEERIGEKNYYKILNE
HHHHHHHHCCCEEEECCCCEEEEECCCCHHHHHHHHCCCCEEEEEHHHCCCCHHHHHHHH
AKISIPKLFKPEEIDRPVIVKLPEAKRKVERGFFFAVNKEDFEAKLNELLRNNVIDNEGL
HHCCCCCCCCCCCCCCCEEEECCHHHHHHHCCEEEEECCHHHHHHHHHHHHHCCCCCCCH
KNMVIEEFVFGAHFNLNYFYSPIFNRLELISVDRRIQSDWDSLYRLPADIQIKLGRIPKL
HHHHHHHHHHCCEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCHH
IEVGHEPVTIRESLLEKVFEIGYRFVDATQKLEPPGIIGPFTLQVMVTPDLDLVVYDVAP
HHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEECCCCCEEEEECCC
RIGGGTNVYMGTGSQYSKFYFGKPISLGRRIALEIKHAIINNLTEKILT
CCCCCCEEEEECCCCCCCEECCCCHHHCCCHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA