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The map label for this gene is rpoA2 [H]

Identifier: 15897170

GI number: 15897170

Start: 189372

End: 190559

Strand: Reverse

Name: rpoA2 [H]

Synonym: SSO0223

Alternate gene names: 15897170

Gene position: 190559-189372 (Counterclockwise)

Preceding gene: 15897171

Following gene: 15897169

Centisome position: 6.37

GC content: 35.1

Gene sequence:

>1188_bases
GTGGAAGGCATGATTGATGAGAAAGATAAGCCCTATTTAGAGGAGAAAGTGAAGCAAGCTTCCAATATCCTCCCTCAAAA
AATTGTAGACGATTTGAAAAATTTGATATTAAACAAGGAAATAATAGTGACGAGAGATGAGATTGATAAAATCTTCGATT
TGGCTATTAAAGAGTATAGTGAAGGGTTAATAGCTCCAGGAGAGGCTATTGGAATTGTAGCCGCACAGTCAGTAGGTGAG
CCCGGTACCCAAATGACATTAAGGACTTTCCATTTTGCGGGTATAAGAGAGTTAAATGTAACTTTAGGACTTCCAAGGCT
AATAGAAATTGTGGATGCGAAGAAAGTTCCATCTACTCCAATGATGACTATTTATTTAACTGATGAATACAAGCGTGATA
GGGATAAAGCGTTAGAAGTCGCCAGAAAATTAGAATATACGAAAATAGAAAATGTAGTGAGTTCAACTAGTATCGATATA
GCCTCAATGTCCATTATTCTCCAACTCGATAATGAAATGTTAAAAGATAAAGGCGTTACTGTAGATGATGTTAAAAAAGC
TATAGGTAGATTGAAATTAGGAGATTTTATGATAGAAGAATCTGAGGATAGTACATTAAACATAAATTTCGCTAATATAG
ATAGTATAGCTGCGCTATTTAAACTAAGGGATAAGATACTTAATACCAAAATAAAGGGAATAAAGGGTATAAAACGTGCT
ATAGTCCAGAAAAAGGGCGATGAGTATATCATTTTAACCGATGGTTCAAATTTATCTGGTGTTCTTAGTGTAAAAGGAGT
TGACGTAGCTAAAGTAGAGACTAATAATATCCGTGAGATTGAGGAAGTATTTGGAATAGAAGCGGCAAGGGAAATTATAA
TTAGGGAGATTAGTAAAGTATTAGCAGAACAAGGATTGGATGTTGATATAAGGCATATATTATTAATTGCGGACGTGATG
ACGAGAACGGGTATTGTAAGGCAGATAGGTAGACATGGTGTAACTGGAGAGAAGAATAGTGTATTAGCAAGAGCTGCATT
TGAAGTTACTGTAAAACATCTTTTAGATGCTGCGGCTAGAGGAGATGTAGAAGAATTTAAAGGTGTAGTAGAAAACATTA
TAATTGGTCATCCAATTAAACTAGGTACTGGAATGGTTGAATTAACAATGAGGCCGATATTAAGGTGA

Upstream 100 bases:

>100_bases
AAGTTGTTCAAGTAGCGTATGGTGATGATGGTGTATTTCCCATGTATTCAGCTCATGGTAAAACGGTAGATGTAAATAGA
ATCTTTGAGAGAGTCGTGGG

Downstream 100 bases:

>100_bases
TAAAAGTGTCAGAACAACAAGTTTCATTTGAAGGAGAGTTAAAATCACTTTTGAAAACTGGTAAAGTTATTTTTGGTGCT
AAGAGAGCGATAAAATATAT

Product: DNA-directed RNA polymerase subunit A''

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 395; Mature: 395

Protein sequence:

>395_residues
MEGMIDEKDKPYLEEKVKQASNILPQKIVDDLKNLILNKEIIVTRDEIDKIFDLAIKEYSEGLIAPGEAIGIVAAQSVGE
PGTQMTLRTFHFAGIRELNVTLGLPRLIEIVDAKKVPSTPMMTIYLTDEYKRDRDKALEVARKLEYTKIENVVSSTSIDI
ASMSIILQLDNEMLKDKGVTVDDVKKAIGRLKLGDFMIEESEDSTLNINFANIDSIAALFKLRDKILNTKIKGIKGIKRA
IVQKKGDEYIILTDGSNLSGVLSVKGVDVAKVETNNIREIEEVFGIEAAREIIIREISKVLAEQGLDVDIRHILLIADVM
TRTGIVRQIGRHGVTGEKNSVLARAAFEVTVKHLLDAAARGDVEEFKGVVENIIIGHPIKLGTGMVELTMRPILR

Sequences:

>Translated_395_residues
MEGMIDEKDKPYLEEKVKQASNILPQKIVDDLKNLILNKEIIVTRDEIDKIFDLAIKEYSEGLIAPGEAIGIVAAQSVGE
PGTQMTLRTFHFAGIRELNVTLGLPRLIEIVDAKKVPSTPMMTIYLTDEYKRDRDKALEVARKLEYTKIENVVSSTSIDI
ASMSIILQLDNEMLKDKGVTVDDVKKAIGRLKLGDFMIEESEDSTLNINFANIDSIAALFKLRDKILNTKIKGIKGIKRA
IVQKKGDEYIILTDGSNLSGVLSVKGVDVAKVETNNIREIEEVFGIEAAREIIIREISKVLAEQGLDVDIRHILLIADVM
TRTGIVRQIGRHGVTGEKNSVLARAAFEVTVKHLLDAAARGDVEEFKGVVENIIIGHPIKLGTGMVELTMRPILR
>Mature_395_residues
MEGMIDEKDKPYLEEKVKQASNILPQKIVDDLKNLILNKEIIVTRDEIDKIFDLAIKEYSEGLIAPGEAIGIVAAQSVGE
PGTQMTLRTFHFAGIRELNVTLGLPRLIEIVDAKKVPSTPMMTIYLTDEYKRDRDKALEVARKLEYTKIENVVSSTSIDI
ASMSIILQLDNEMLKDKGVTVDDVKKAIGRLKLGDFMIEESEDSTLNINFANIDSIAALFKLRDKILNTKIKGIKGIKRA
IVQKKGDEYIILTDGSNLSGVLSVKGVDVAKVETNNIREIEEVFGIEAAREIIIREISKVLAEQGLDVDIRHILLIADVM
TRTGIVRQIGRHGVTGEKNSVLARAAFEVTVKHLLDAAARGDVEEFKGVVENIIIGHPIKLGTGMVELTMRPILR

Specific function: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates [H]

COG id: COG0086

COG function: function code K; DNA-directed RNA polymerase, beta' subunit/160 kD subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RNA polymerase beta' chain family [H]

Homologues:

Organism=Homo sapiens, GI39725938, Length=359, Percent_Identity=34.8189415041783, Blast_Score=203, Evalue=3e-52,
Organism=Homo sapiens, GI4505939, Length=451, Percent_Identity=29.9334811529933, Blast_Score=194, Evalue=1e-49,
Organism=Homo sapiens, GI103471997, Length=78, Percent_Identity=53.8461538461538, Blast_Score=86, Evalue=7e-17,
Organism=Caenorhabditis elegans, GI25145495, Length=372, Percent_Identity=34.1397849462366, Blast_Score=196, Evalue=2e-50,
Organism=Caenorhabditis elegans, GI71987878, Length=434, Percent_Identity=31.7972350230415, Blast_Score=192, Evalue=3e-49,
Organism=Caenorhabditis elegans, GI71998295, Length=140, Percent_Identity=39.2857142857143, Blast_Score=87, Evalue=2e-17,
Organism=Saccharomyces cerevisiae, GI6320061, Length=411, Percent_Identity=30.4136253041363, Blast_Score=195, Evalue=1e-50,
Organism=Saccharomyces cerevisiae, GI6324690, Length=400, Percent_Identity=33.75, Blast_Score=192, Evalue=5e-50,
Organism=Saccharomyces cerevisiae, GI6324917, Length=73, Percent_Identity=58.9041095890411, Blast_Score=88, Evalue=2e-18,
Organism=Drosophila melanogaster, GI17530899, Length=394, Percent_Identity=33.248730964467, Blast_Score=205, Evalue=5e-53,
Organism=Drosophila melanogaster, GI281360912, Length=344, Percent_Identity=36.046511627907, Blast_Score=199, Evalue=2e-51,
Organism=Drosophila melanogaster, GI17647875, Length=160, Percent_Identity=34.375, Blast_Score=97, Evalue=2e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007081
- InterPro:   IPR012757 [H]

Pfam domain/function: PF04998 RNA_pol_Rpb1_5 [H]

EC number: =2.7.7.6 [H]

Molecular weight: Translated: 43806; Mature: 43806

Theoretical pI: Translated: 5.43; Mature: 5.43

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEGMIDEKDKPYLEEKVKQASNILPQKIVDDLKNLILNKEIIVTRDEIDKIFDLAIKEYS
CCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHH
EGLIAPGEAIGIVAAQSVGEPGTQMTLRTFHFAGIRELNVTLGLPRLIEIVDAKKVPSTP
CCCCCCCCHHEEEEHHCCCCCCCCEEEHHHHHCCCEEEEEEECCHHHHHHHHHCCCCCCC
MMTIYLTDEYKRDRDKALEVARKLEYTKIENVVSSTSIDIASMSIILQLDNEMLKDKGVT
EEEEEECCHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHEEEEEEECHHHHHHCCCC
VDDVKKAIGRLKLGDFMIEESEDSTLNINFANIDSIAALFKLRDKILNTKIKGIKGIKRA
HHHHHHHHCCCCHHHEEEECCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IVQKKGDEYIILTDGSNLSGVLSVKGVDVAKVETNNIREIEEVFGIEAAREIIIREISKV
HHHCCCCCEEEEECCCCCCEEEEECCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHH
LAEQGLDVDIRHILLIADVMTRTGIVRQIGRHGVTGEKNSVLARAAFEVTVKHLLDAAAR
HHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHC
GDVEEFKGVVENIIIGHPIKLGTGMVELTMRPILR
CCHHHHHHHHHHHHCCCCHHHCCCHHHHHHHHCCC
>Mature Secondary Structure
MEGMIDEKDKPYLEEKVKQASNILPQKIVDDLKNLILNKEIIVTRDEIDKIFDLAIKEYS
CCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHH
EGLIAPGEAIGIVAAQSVGEPGTQMTLRTFHFAGIRELNVTLGLPRLIEIVDAKKVPSTP
CCCCCCCCHHEEEEHHCCCCCCCCEEEHHHHHCCCEEEEEEECCHHHHHHHHHCCCCCCC
MMTIYLTDEYKRDRDKALEVARKLEYTKIENVVSSTSIDIASMSIILQLDNEMLKDKGVT
EEEEEECCHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHEEEEEEECHHHHHHCCCC
VDDVKKAIGRLKLGDFMIEESEDSTLNINFANIDSIAALFKLRDKILNTKIKGIKGIKRA
HHHHHHHHCCCCHHHEEEECCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IVQKKGDEYIILTDGSNLSGVLSVKGVDVAKVETNNIREIEEVFGIEAAREIIIREISKV
HHHCCCCCEEEEECCCCCCEEEEECCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHH
LAEQGLDVDIRHILLIADVMTRTGIVRQIGRHGVTGEKNSVLARAAFEVTVKHLLDAAAR
HHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHC
GDVEEFKGVVENIIIGHPIKLGTGMVELTMRPILR
CCHHHHHHHHHHHHCCCCHHHCCCHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA