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The map label for this gene is pld

Identifier: 15893193

GI number: 15893193

Start: 1170552

End: 1171154

Strand: Reverse

Name: pld

Synonym: RC1270

Alternate gene names: 15893193

Gene position: 1171154-1170552 (Counterclockwise)

Preceding gene: 15893194

Following gene: 15893191

Centisome position: 92.31

GC content: 31.67

Gene sequence:

>603_bases
ATGAAGAGAAAAAATAATAAATTTATAGAAATATCTATTGCCTTTATTTTGGGAATTGCTTTAGGTCTTTATGGACAGAA
TCCGGATTATTTTACTAATCTAATAAGTCAAAAATCATTAGCTTTATCTGCTCTGCAAATAAAGCATTACAATATTTCAG
AGCTTTCAAGAAGTAAAGTTAGTACATGTTTTACTCCGCCTGCCGGTTGTACTAAGTTTATAGCCAATCAGATAGATAAA
GCTGAAGAATCTATTTATATGCAGGCATACGGTATGAGCGATGCGTTAATTACTACTGCACTTATTAATGCACAAGCGCG
AGGAGTAAAGGTTAGAATATTGCTTGATCGTAGTAATTTAAAGCAAAAATTTTCTAAATTACATGAATTACAACGAGCAA
AAATTGATGTAGATATAGATAAAGTACCGGGAATCGCTCATAATAAAGTTATAATTATTGATAAAAAGAAAGTAATAACC
GGTTCGTTTAATTTCACGGCTGCTGCCGATAAACGTAATGCTGAAAATGTAATTATTATAGAAGATCAGGAGCTAGCAGA
ATCTTATTTACAAAATTGGTTAAACAGAAAGGCGAGCAACTGA

Upstream 100 bases:

>100_bases
CATGGCAATCTCATGAGATTTTGCTTCGTCAATTACTTTGTACTTTTCCTCGCAATGACGGAAAAGCCGATCTATGCAAT
GCCTAAAATATAAATAAGTC

Downstream 100 bases:

>100_bases
GAGGAGATTCCCACTATGTCATTCTTGCGAAAGCAGGAATCTAGTAGCTAAAAGATATAAATAAAACATTTTTGATGACA
TTCACTAGCTTGTTTGAAAT

Product: hypothetical protein

Products: NA

Alternate protein names: PLD; Choline phosphatase

Number of amino acids: Translated: 200; Mature: 200

Protein sequence:

>200_residues
MKRKNNKFIEISIAFILGIALGLYGQNPDYFTNLISQKSLALSALQIKHYNISELSRSKVSTCFTPPAGCTKFIANQIDK
AEESIYMQAYGMSDALITTALINAQARGVKVRILLDRSNLKQKFSKLHELQRAKIDVDIDKVPGIAHNKVIIIDKKKVIT
GSFNFTAAADKRNAENVIIIEDQELAESYLQNWLNRKASN

Sequences:

>Translated_200_residues
MKRKNNKFIEISIAFILGIALGLYGQNPDYFTNLISQKSLALSALQIKHYNISELSRSKVSTCFTPPAGCTKFIANQIDK
AEESIYMQAYGMSDALITTALINAQARGVKVRILLDRSNLKQKFSKLHELQRAKIDVDIDKVPGIAHNKVIIIDKKKVIT
GSFNFTAAADKRNAENVIIIEDQELAESYLQNWLNRKASN
>Mature_200_residues
MKRKNNKFIEISIAFILGIALGLYGQNPDYFTNLISQKSLALSALQIKHYNISELSRSKVSTCFTPPAGCTKFIANQIDK
AEESIYMQAYGMSDALITTALINAQARGVKVRILLDRSNLKQKFSKLHELQRAKIDVDIDKVPGIAHNKVIIIDKKKVIT
GSFNFTAAADKRNAENVIIIEDQELAESYLQNWLNRKASN

Specific function: Could be a virulence factor

COG id: COG1502

COG function: function code I; Phosphatidylserine/phosphatidylglycerophosphate/cardiolipin synthases and related enzymes

Gene ontology:

Cell location: Secreted (Potential)

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PLD phosphodiesterase domain

Homologues:

Organism=Homo sapiens, GI270265812, Length=103, Percent_Identity=35.9223300970874, Blast_Score=71, Evalue=8e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PLD_RICCN (Q92G53)

Other databases:

- EMBL:   AE006914
- PIR:   F97858
- RefSeq:   NP_360907.1
- ProteinModelPortal:   Q92G53
- SMR:   Q92G53
- GeneID:   928420
- GenomeReviews:   AE006914_GR
- KEGG:   rco:RC1270
- NMPDR:   fig|272944.1.peg.1270
- OMA:   DNRNAEN
- ProtClustDB:   CLSK871092
- BioCyc:   RCON272944:RC1270-MONOMER
- BRENDA:   3.1.4.4
- GO:   GO:0009405
- InterPro:   IPR001736
- SMART:   SM00155

Pfam domain/function: NA

EC number: =3.1.4.4

Molecular weight: Translated: 22418; Mature: 22418

Theoretical pI: Translated: 10.07; Mature: 10.07

Prosite motif: PS50035 PLD

Important sites: ACT_SITE 147-147 ACT_SITE 149-149 ACT_SITE 154-154

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRKNNKFIEISIAFILGIALGLYGQNPDYFTNLISQKSLALSALQIKHYNISELSRSKV
CCCCCCCEEEEEHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHEEECCCHHHHHHHHH
STCFTPPAGCTKFIANQIDKAEESIYMQAYGMSDALITTALINAQARGVKVRILLDRSNL
HHCCCCCCHHHHHHHHHHHHHHHHEEEEECCCCHHHHHHHHHHCCCCCEEEEEEECCHHH
KQKFSKLHELQRAKIDVDIDKVPGIAHNKVIIIDKKKVITGSFNFTAAADKRNAENVIII
HHHHHHHHHHHHHHCCEEHHHCCCCCCCEEEEEECCEEEEECCCEEEECCCCCCCCEEEE
EDQELAESYLQNWLNRKASN
ECHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MKRKNNKFIEISIAFILGIALGLYGQNPDYFTNLISQKSLALSALQIKHYNISELSRSKV
CCCCCCCEEEEEHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHEEECCCHHHHHHHHH
STCFTPPAGCTKFIANQIDKAEESIYMQAYGMSDALITTALINAQARGVKVRILLDRSNL
HHCCCCCCHHHHHHHHHHHHHHHHEEEEECCCCHHHHHHHHHHCCCCCEEEEEEECCHHH
KQKFSKLHELQRAKIDVDIDKVPGIAHNKVIIIDKKKVITGSFNFTAAADKRNAENVIII
HHHHHHHHHHHHHHCCEEHHHCCCCCCCEEEEEECCEEEEECCCEEEECCCCCCCCEEEE
EDQELAESYLQNWLNRKASN
ECHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11557893