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The map label for this gene is lpxK [H]

Identifier: 15893015

GI number: 15893015

Start: 1017829

End: 1018794

Strand: Reverse

Name: lpxK [H]

Synonym: RC1092

Alternate gene names: 15893015

Gene position: 1018794-1017829 (Counterclockwise)

Preceding gene: 15893016

Following gene: 15893014

Centisome position: 80.3

GC content: 30.75

Gene sequence:

>966_bases
ATGATCAAACTTTTATATCCTGAATTTTGGCAGAAGCGAAATATTATAGCTTATTTGCTTTTGCCTATAAGCGTGATATA
TAAATTTTTAGGCTATTTACGAGCTAGTTTAGCACGTCCTATTATGTTGCCTGCTAAAGTTATTTGTGTCGGTAATTGTA
GCGTAGGAGGTACGGGTAAGACGCAGATAGTAATGTATCTAGCCAAATTACTAAAATCTAGAAATGTAAGTTTTGTAATA
GTAACTAAGGCTTATGGTAGTAACCTTAAAAGTGCAACTACCATACATCAAGGACATACAGCATTAGAGGTAGGAGATGA
GGGGGTAATACTTGCAAAGTACGGAGCAGTTATTGCGACTAAAAATATTAAAGAGATTGTGCCGTTACTTAACGAGCTTA
AACCTGATATAATAATAGTTGATGATTTCCTACAAAATCCTTATTTTCATAAAGACTTTACTATAGTCTCAGTAGATAGC
CAAAGGCTTTTCGGCAACGGTTTTCTAATTCCTGCCGGTCCTTTAAGACAATATCCAAATAAAGCCCTTGATGCAGCTGA
TTTAATTTTTTTAGTCAGTAGCCACCAAGATAAAATACCAAATATTTTAACTCCTTATGTCAATAAGTTAATAAATGCTC
AAATAGTTCCTTCAAATAATATAGATAAAACTAAAAATTATTTTGCTTTTAGCGGTATCGGTAATCCTGAGCGTTTCTTT
GCGACTTTAAAAAATTACGGATTAAATATAACCGGTTACAAAATTTTTCCTGATCATTATAATTATTTACAAGCAGATTT
AGAAAATTTATATTCATTAGCTAAAGAGCATAATGCTACCTTAGTTACTACAAGAAAAGATCATGTTAAGTTTAATGATT
TAAATAATAATATTGTCTGTCTAGATGTAGAATTATCTATAAACCATCCTGATTTATTAAATGAAAAAATTTTTAAAAAA
GCTTAG

Upstream 100 bases:

>100_bases
TGGTAATGCAACGGGTGAACATTTGCATTTTGAAATTCTGTTAGATAATAAAGCAATCAATCCGTTTGACTTTATTTTTA
ACTACCATAAATGTTAAACT

Downstream 100 bases:

>100_bases
ATATTTAATTGAGTATTTTATCGTTGTTATATTCCTGAAAGTAATAGGAATATTCGGTGTAGATAAAGCGGCGGATATTT
GTAGTTTTATAGCAAGAAAA

Product: tetraacyldisaccharide 4'-kinase

Products: NA

Alternate protein names: Lipid A 4'-kinase [H]

Number of amino acids: Translated: 321; Mature: 321

Protein sequence:

>321_residues
MIKLLYPEFWQKRNIIAYLLLPISVIYKFLGYLRASLARPIMLPAKVICVGNCSVGGTGKTQIVMYLAKLLKSRNVSFVI
VTKAYGSNLKSATTIHQGHTALEVGDEGVILAKYGAVIATKNIKEIVPLLNELKPDIIIVDDFLQNPYFHKDFTIVSVDS
QRLFGNGFLIPAGPLRQYPNKALDAADLIFLVSSHQDKIPNILTPYVNKLINAQIVPSNNIDKTKNYFAFSGIGNPERFF
ATLKNYGLNITGYKIFPDHYNYLQADLENLYSLAKEHNATLVTTRKDHVKFNDLNNNIVCLDVELSINHPDLLNEKIFKK
A

Sequences:

>Translated_321_residues
MIKLLYPEFWQKRNIIAYLLLPISVIYKFLGYLRASLARPIMLPAKVICVGNCSVGGTGKTQIVMYLAKLLKSRNVSFVI
VTKAYGSNLKSATTIHQGHTALEVGDEGVILAKYGAVIATKNIKEIVPLLNELKPDIIIVDDFLQNPYFHKDFTIVSVDS
QRLFGNGFLIPAGPLRQYPNKALDAADLIFLVSSHQDKIPNILTPYVNKLINAQIVPSNNIDKTKNYFAFSGIGNPERFF
ATLKNYGLNITGYKIFPDHYNYLQADLENLYSLAKEHNATLVTTRKDHVKFNDLNNNIVCLDVELSINHPDLLNEKIFKK
A
>Mature_321_residues
MIKLLYPEFWQKRNIIAYLLLPISVIYKFLGYLRASLARPIMLPAKVICVGNCSVGGTGKTQIVMYLAKLLKSRNVSFVI
VTKAYGSNLKSATTIHQGHTALEVGDEGVILAKYGAVIATKNIKEIVPLLNELKPDIIIVDDFLQNPYFHKDFTIVSVDS
QRLFGNGFLIPAGPLRQYPNKALDAADLIFLVSSHQDKIPNILTPYVNKLINAQIVPSNNIDKTKNYFAFSGIGNPERFF
ATLKNYGLNITGYKIFPDHYNYLQADLENLYSLAKEHNATLVTTRKDHVKFNDLNNNIVCLDVELSINHPDLLNEKIFKK
A

Specific function: Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) [H]

COG id: COG1663

COG function: function code M; Tetraacyldisaccharide-1-P 4'-kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the lpxK family [H]

Homologues:

Organism=Escherichia coli, GI1787144, Length=318, Percent_Identity=31.1320754716981, Blast_Score=140, Evalue=1e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003758 [H]

Pfam domain/function: PF02606 LpxK [H]

EC number: =2.7.1.130 [H]

Molecular weight: Translated: 36059; Mature: 36059

Theoretical pI: Translated: 9.59; Mature: 9.59

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIKLLYPEFWQKRNIIAYLLLPISVIYKFLGYLRASLARPIMLPAKVICVGNCSVGGTGK
CEEEECHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCCCH
TQIVMYLAKLLKSRNVSFVIVTKAYGSNLKSATTIHQGHTALEVGDEGVILAKYGAVIAT
HHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCEEEECCCEEEEECCCCEEEEECCCEEEE
KNIKEIVPLLNELKPDIIIVDDFLQNPYFHKDFTIVSVDSQRLFGNGFLIPAGPLRQYPN
CCHHHHHHHHHHCCCCEEEEEHHHCCCCCCCCEEEEEECCCEEECCCEEECCCHHHHCCC
KALDAADLIFLVSSHQDKIPNILTPYVNKLINAQIVPSNNIDKTKNYFAFSGIGNPERFF
HHCCHHHEEEEEECCCCCCCCHHHHHHHHHHCCEECCCCCCCCCCCEEEEECCCCHHHHH
ATLKNYGLNITGYKIFPDHYNYLQADLENLYSLAKEHNATLVTTRKDHVKFNDLNNNIVC
HHHHHCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHCCCEEEEEECCCEEEECCCCCEEE
LDVELSINHPDLLNEKIFKKA
EEEEEECCCCHHHHHHHHHCC
>Mature Secondary Structure
MIKLLYPEFWQKRNIIAYLLLPISVIYKFLGYLRASLARPIMLPAKVICVGNCSVGGTGK
CEEEECHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCCCH
TQIVMYLAKLLKSRNVSFVIVTKAYGSNLKSATTIHQGHTALEVGDEGVILAKYGAVIAT
HHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCEEEECCCEEEEECCCCEEEEECCCEEEE
KNIKEIVPLLNELKPDIIIVDDFLQNPYFHKDFTIVSVDSQRLFGNGFLIPAGPLRQYPN
CCHHHHHHHHHHCCCCEEEEEHHHCCCCCCCCEEEEEECCCEEECCCEEECCCHHHHCCC
KALDAADLIFLVSSHQDKIPNILTPYVNKLINAQIVPSNNIDKTKNYFAFSGIGNPERFF
HHCCHHHEEEEEECCCCCCCCHHHHHHHHHHCCEECCCCCCCCCCCEEEEECCCCHHHHH
ATLKNYGLNITGYKIFPDHYNYLQADLENLYSLAKEHNATLVTTRKDHVKFNDLNNNIVC
HHHHHCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHCCCEEEEEECCCEEEECCCCCEEE
LDVELSINHPDLLNEKIFKKA
EEEEEECCCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA