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The map label for this gene is sucC [H]

Identifier: 15892522

GI number: 15892522

Start: 585799

End: 586959

Strand: Reverse

Name: sucC [H]

Synonym: RC0599

Alternate gene names: 15892522

Gene position: 586959-585799 (Counterclockwise)

Preceding gene: 15892523

Following gene: 15892521

Centisome position: 46.26

GC content: 36.52

Gene sequence:

>1161_bases
ATGAATATTCATGAATATCAAGCAAAAGAGATTTTAAGAAAATACGGCGTACCTACTTCCACCGGGCTAGTTGTTACGAA
AACCGAAAAGATTAATGAAACCATAGATAAATTAAATACGGAAGTATATGTGGTTAAAGCACAAATACATGCCGGCGGTA
GAGGTAAAGCAGGCGGTGTTAAGGTTGTTAAGAGTAAAGAAGAAGCCAAAAAAGTTGCTCATGACATGTTTGGTATTAAT
TTAGTAACGCATCAAACAGGACCTCAAGGACAAAAAGTAAACCGTCTTTATATCGAATCAGGTTGTGATATTTTAAAAGA
ATATTATTTTAGTATAGTATTTGATAGATCGGCTAGCTGTATTACTTTTATAGCTTCTACAGAAGGAGGAATTGATATTG
AAGCAGTAGCAGAAAAAACTCCGGACAAAATTATTAAATTTTCCGTTGATCCTGCAACCGGTTTACAAGATTTTCATATG
CGAGGCATAGCTTATGAGTTAGGCTTTAAGGATAACCAAGCTAAACAGATGAAAGAAATAGTAAAATCAGTCTATAATGC
TTTTATTGAAACCGATGCAACACAAATTGAAATCAACCCATTAATTGTAAATAGCGACGGGAACTTATTAGCTTTAGATG
CAAAAATTACTTTTGACGATAACGGCTTATTTCGGCATCCGAATATTACGGCAATGCGTGATCATGATGAAGAAGATCCT
CTAGAAACTAGAGCCGCAAATGCAGGACTTAGCTATGTAAAAATGGACGGTAATATCGGTTGTATGGTTAACGGTGCCGG
TCTTGCCATGGCCACTATGGATATTATTAAACTTTACGGTGCTTCGCCTGCTAATTTCTTGGATGTCGGTGGTGGAGCTG
ATCGTGAGCGTGTAAAAGAAGCTTTAAAAATAATTTTATCTGATAAAGAAGTACAAGGGATTCTAGTTAATATTTTCGGC
GGTATCATGCGTTGTGATATTATAGCAGAAGGGATTATTGCCGCTGCAAAAGACATAGGTATAAAAGTACCGTTAGTAGT
TCGTTTAGCCGGTACAAACGTTGAAAAAGGCGAAGAAATTTTATCAAATTCCGGTTTAGCAATAATACCGGCACATGATT
TAGCAGATGCGGCAAATAAAATAGTTGAAGCGATACGGTAG

Upstream 100 bases:

>100_bases
GTGCTAATAAGTTTATCACTTTTGATAAAGACCTAGTAAGAGAAGTTAAAAATGCATCTTATCCATAAAAATTAATAGCA
ATTTAAATAAATTATTTAAA

Downstream 100 bases:

>100_bases
ATAACCGTCATGAGCTATACAGGCATTGACCTTGTTGTATAGCTCGAAAAACCAGTTCAGTGTCATACCGTGGCTTGACC
ACAGTATCCATAAAAAAATT

Product: succinyl-CoA synthetase subunit beta

Products: NA

Alternate protein names: Succinyl-CoA synthetase subunit beta; SCS-beta [H]

Number of amino acids: Translated: 386; Mature: 386

Protein sequence:

>386_residues
MNIHEYQAKEILRKYGVPTSTGLVVTKTEKINETIDKLNTEVYVVKAQIHAGGRGKAGGVKVVKSKEEAKKVAHDMFGIN
LVTHQTGPQGQKVNRLYIESGCDILKEYYFSIVFDRSASCITFIASTEGGIDIEAVAEKTPDKIIKFSVDPATGLQDFHM
RGIAYELGFKDNQAKQMKEIVKSVYNAFIETDATQIEINPLIVNSDGNLLALDAKITFDDNGLFRHPNITAMRDHDEEDP
LETRAANAGLSYVKMDGNIGCMVNGAGLAMATMDIIKLYGASPANFLDVGGGADRERVKEALKIILSDKEVQGILVNIFG
GIMRCDIIAEGIIAAAKDIGIKVPLVVRLAGTNVEKGEEILSNSGLAIIPAHDLADAANKIVEAIR

Sequences:

>Translated_386_residues
MNIHEYQAKEILRKYGVPTSTGLVVTKTEKINETIDKLNTEVYVVKAQIHAGGRGKAGGVKVVKSKEEAKKVAHDMFGIN
LVTHQTGPQGQKVNRLYIESGCDILKEYYFSIVFDRSASCITFIASTEGGIDIEAVAEKTPDKIIKFSVDPATGLQDFHM
RGIAYELGFKDNQAKQMKEIVKSVYNAFIETDATQIEINPLIVNSDGNLLALDAKITFDDNGLFRHPNITAMRDHDEEDP
LETRAANAGLSYVKMDGNIGCMVNGAGLAMATMDIIKLYGASPANFLDVGGGADRERVKEALKIILSDKEVQGILVNIFG
GIMRCDIIAEGIIAAAKDIGIKVPLVVRLAGTNVEKGEEILSNSGLAIIPAHDLADAANKIVEAIR
>Mature_386_residues
MNIHEYQAKEILRKYGVPTSTGLVVTKTEKINETIDKLNTEVYVVKAQIHAGGRGKAGGVKVVKSKEEAKKVAHDMFGIN
LVTHQTGPQGQKVNRLYIESGCDILKEYYFSIVFDRSASCITFIASTEGGIDIEAVAEKTPDKIIKFSVDPATGLQDFHM
RGIAYELGFKDNQAKQMKEIVKSVYNAFIETDATQIEINPLIVNSDGNLLALDAKITFDDNGLFRHPNITAMRDHDEEDP
LETRAANAGLSYVKMDGNIGCMVNGAGLAMATMDIIKLYGASPANFLDVGGGADRERVKEALKIILSDKEVQGILVNIFG
GIMRCDIIAEGIIAAAKDIGIKVPLVVRLAGTNVEKGEEILSNSGLAIIPAHDLADAANKIVEAIR

Specific function: Tricarboxylic acid cycle. [C]

COG id: COG0045

COG function: function code C; Succinyl-CoA synthetase, beta subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ATP-grasp domain [H]

Homologues:

Organism=Homo sapiens, GI11321583, Length=390, Percent_Identity=46.1538461538462, Blast_Score=345, Evalue=4e-95,
Organism=Homo sapiens, GI157779135, Length=383, Percent_Identity=44.3864229765013, Blast_Score=324, Evalue=7e-89,
Organism=Homo sapiens, GI294862256, Length=363, Percent_Identity=43.801652892562, Blast_Score=303, Evalue=2e-82,
Organism=Escherichia coli, GI1786948, Length=385, Percent_Identity=52.2077922077922, Blast_Score=400, Evalue=1e-113,
Organism=Caenorhabditis elegans, GI17539378, Length=394, Percent_Identity=43.9086294416244, Blast_Score=333, Evalue=1e-91,
Organism=Caenorhabditis elegans, GI17567829, Length=391, Percent_Identity=44.5012787723785, Blast_Score=332, Evalue=2e-91,
Organism=Saccharomyces cerevisiae, GI6321683, Length=393, Percent_Identity=45.29262086514, Blast_Score=343, Evalue=3e-95,
Organism=Drosophila melanogaster, GI21356231, Length=393, Percent_Identity=46.8193384223919, Blast_Score=338, Evalue=4e-93,
Organism=Drosophila melanogaster, GI161078106, Length=386, Percent_Identity=44.559585492228, Blast_Score=323, Evalue=1e-88,
Organism=Drosophila melanogaster, GI24645208, Length=386, Percent_Identity=44.559585492228, Blast_Score=323, Evalue=1e-88,
Organism=Drosophila melanogaster, GI281361397, Length=387, Percent_Identity=44.702842377261, Blast_Score=321, Evalue=5e-88,
Organism=Drosophila melanogaster, GI281361395, Length=387, Percent_Identity=44.702842377261, Blast_Score=321, Evalue=5e-88,

Paralogues:

None

Copy number: 340 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2361 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 3,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011761
- InterPro:   IPR013650
- InterPro:   IPR013815
- InterPro:   IPR013816
- InterPro:   IPR005811
- InterPro:   IPR017866
- InterPro:   IPR005809
- InterPro:   IPR016102 [H]

Pfam domain/function: PF08442 ATP-grasp_2; PF00549 Ligase_CoA [H]

EC number: =6.2.1.5 [H]

Molecular weight: Translated: 41821; Mature: 41821

Theoretical pI: Translated: 5.49; Mature: 5.49

Prosite motif: PS50975 ATP_GRASP ; PS01217 SUCCINYL_COA_LIG_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIHEYQAKEILRKYGVPTSTGLVVTKTEKINETIDKLNTEVYVVKAQIHAGGRGKAGGV
CCCHHHHHHHHHHHCCCCCCCCEEEEEHHHHHHHHHHCCCEEEEEEEEEECCCCCCCCCE
KVVKSKEEAKKVAHDMFGINLVTHQTGPQGQKVNRLYIESGCDILKEYYFSIVFDRSASC
EEEECHHHHHHHHHHHHCEEEEEECCCCCCCCEEEEEEHHHHHHHHHHHHEEEECCCCCE
ITFIASTEGGIDIEAVAEKTPDKIIKFSVDPATGLQDFHMRGIAYELGFKDNQAKQMKEI
EEEEEECCCCCEEEECCCCCCCCEEEEECCCCCCCHHHHHCCEEEEECCCCCHHHHHHHH
VKSVYNAFIETDATQIEINPLIVNSDGNLLALDAKITFDDNGLFRHPNITAMRDHDEEDP
HHHHHHHHHCCCCCEEEEEEEEECCCCCEEEEEEEEEECCCCEEECCCEEEECCCCCCCC
LETRAANAGLSYVKMDGNIGCMVNGAGLAMATMDIIKLYGASPANFLDVGGGADRERVKE
HHHHHHCCCCEEEEECCCEEEEEECCCHHHHHHHHHHHHCCCCCCEEECCCCCCHHHHHH
ALKIILSDKEVQGILVNIFGGIMRCDIIAEGIIAAAKDIGIKVPLVVRLAGTNVEKGEEI
HHHHHHCCCCHHEEHHHHHHHHHHHHHHHHHHHHHHHHCCEECEEEEEEECCCCHHHHHH
LSNSGLAIIPAHDLADAANKIVEAIR
HHCCCEEEEECHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNIHEYQAKEILRKYGVPTSTGLVVTKTEKINETIDKLNTEVYVVKAQIHAGGRGKAGGV
CCCHHHHHHHHHHHCCCCCCCCEEEEEHHHHHHHHHHCCCEEEEEEEEEECCCCCCCCCE
KVVKSKEEAKKVAHDMFGINLVTHQTGPQGQKVNRLYIESGCDILKEYYFSIVFDRSASC
EEEECHHHHHHHHHHHHCEEEEEECCCCCCCCEEEEEEHHHHHHHHHHHHEEEECCCCCE
ITFIASTEGGIDIEAVAEKTPDKIIKFSVDPATGLQDFHMRGIAYELGFKDNQAKQMKEI
EEEEEECCCCCEEEECCCCCCCCEEEEECCCCCCCHHHHHCCEEEEECCCCCHHHHHHHH
VKSVYNAFIETDATQIEINPLIVNSDGNLLALDAKITFDDNGLFRHPNITAMRDHDEEDP
HHHHHHHHHCCCCCEEEEEEEEECCCCCEEEEEEEEEECCCCEEECCCEEEECCCCCCCC
LETRAANAGLSYVKMDGNIGCMVNGAGLAMATMDIIKLYGASPANFLDVGGGADRERVKE
HHHHHHCCCCEEEEECCCEEEEEECCCHHHHHHHHHHHHCCCCCCEEECCCCCCHHHHHH
ALKIILSDKEVQGILVNIFGGIMRCDIIAEGIIAAAKDIGIKVPLVVRLAGTNVEKGEEI
HHHHHHCCCCHHEEHHHHHHHHHHHHHHHHHHHHHHHHCCEECEEEEEEECCCCHHHHHH
LSNSGLAIIPAHDLADAANKIVEAIR
HHCCCEEEEECHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA