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The map label for this gene is mdtB [H]

Identifier: 15892489

GI number: 15892489

Start: 558213

End: 558677

Strand: Reverse

Name: mdtB [H]

Synonym: RC0566

Alternate gene names: 15892489

Gene position: 558677-558213 (Counterclockwise)

Preceding gene: 15892490

Following gene: 15892488

Centisome position: 44.03

GC content: 37.85

Gene sequence:

>465_bases
ATGCCTTATTCCTATACGGGACAAATCTTAGTTTTTACCGACGCCGCTCAAACTATTTCTTTTGATGCGATGGTGCAAGA
ACAACAACAAGTAAGTGATGTATTACTTAAAAATCCTAATATAGATTCATTTTTTTCTGCCGTAGGTGTTTCAGGTAGAA
ACTCTGCCGTAAATCAGGGTACGATTTTGATTAGCTTAAAACCTCGTGATCAAAGAATAGGAGCTGACGCCGTTATAGAT
CAGTTACGTTCAAAACTAAATCATTTAGTAGGTTTAAGGGTATATATCCAGAACGTACCTACTATTACGATCGACGGACC
AGCAACCAAAAGCCAATATCAATATACTATGCAAGAACTCGATCAAGATGTGCTATTTAGCTTTGCACCGAAATTAAAGG
ACAAGCTCGCACGACTGCCAGGTTTTATTAACGTAACTTCGGATTTACAAATAGCACAGCCATAA

Upstream 100 bases:

>100_bases
TAACAACAGTAGTAGAGCATTCAAAAACTACTATGCTTATATTTTTCTCTTAGTAATCATCGCAACGGCTTATTTATTTG
GGAAAGTACGCAAAGGCTTT

Downstream 100 bases:

>100_bases
ACTTTAGTGCAGATTGATAGATATAAGGCTGCAAAACTCGGTATATTAGTCGAGCACGTCCAGAATATCTTATATGCAGC
TTACGGTGCTGAGCAGATTT

Product: RND efflux transporter

Products: NA

Alternate protein names: Multidrug transporter MdtB [H]

Number of amino acids: Translated: 154; Mature: 153

Protein sequence:

>154_residues
MPYSYTGQILVFTDAAQTISFDAMVQEQQQVSDVLLKNPNIDSFFSAVGVSGRNSAVNQGTILISLKPRDQRIGADAVID
QLRSKLNHLVGLRVYIQNVPTITIDGPATKSQYQYTMQELDQDVLFSFAPKLKDKLARLPGFINVTSDLQIAQP

Sequences:

>Translated_154_residues
MPYSYTGQILVFTDAAQTISFDAMVQEQQQVSDVLLKNPNIDSFFSAVGVSGRNSAVNQGTILISLKPRDQRIGADAVID
QLRSKLNHLVGLRVYIQNVPTITIDGPATKSQYQYTMQELDQDVLFSFAPKLKDKLARLPGFINVTSDLQIAQP
>Mature_153_residues
PYSYTGQILVFTDAAQTISFDAMVQEQQQVSDVLLKNPNIDSFFSAVGVSGRNSAVNQGTILISLKPRDQRIGADAVIDQ
LRSKLNHLVGLRVYIQNVPTITIDGPATKSQYQYTMQELDQDVLFSFAPKLKDKLARLPGFINVTSDLQIAQP

Specific function: Could Be A Drug Efflux Pump (By Similarity). [C]

COG id: COG0841

COG function: function code V; Cation/multidrug efflux pump

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AcrB/AcrD/AcrF (TC 2.A.6) family [H]

Homologues:

Organism=Escherichia coli, GI1788390, Length=137, Percent_Identity=37.956204379562, Blast_Score=96, Evalue=2e-21,
Organism=Escherichia coli, GI1788391, Length=150, Percent_Identity=36, Blast_Score=81, Evalue=3e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001036
- InterPro:   IPR022831 [H]

Pfam domain/function: PF00873 ACR_tran [H]

EC number: NA

Molecular weight: Translated: 17032; Mature: 16900

Theoretical pI: Translated: 5.83; Mature: 5.83

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPYSYTGQILVFTDAAQTISFDAMVQEQQQVSDVLLKNPNIDSFFSAVGVSGRNSAVNQG
CCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCCCCC
TILISLKPRDQRIGADAVIDQLRSKLNHLVGLRVYIQNVPTITIDGPATKSQYQYTMQEL
EEEEEECCCCHHCCHHHHHHHHHHHHHHHHHHHEEECCCCEEEECCCCCCHHHHHHHHHH
DQDVLFSFAPKLKDKLARLPGFINVTSDLQIAQP
CHHHHHHHHHHHHHHHHHCCCEEEECCCEEECCC
>Mature Secondary Structure 
PYSYTGQILVFTDAAQTISFDAMVQEQQQVSDVLLKNPNIDSFFSAVGVSGRNSAVNQG
CCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCCCCC
TILISLKPRDQRIGADAVIDQLRSKLNHLVGLRVYIQNVPTITIDGPATKSQYQYTMQEL
EEEEEECCCCHHCCHHHHHHHHHHHHHHHHHHHEEECCCCEEEECCCCCCHHHHHHHHHH
DQDVLFSFAPKLKDKLARLPGFINVTSDLQIAQP
CHHHHHHHHHHHHHHHHHCCCEEEECCCEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA