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The map label for this gene is kdsB [H]

Identifier: 15892447

GI number: 15892447

Start: 514186

End: 514926

Strand: Reverse

Name: kdsB [H]

Synonym: RC0524

Alternate gene names: 15892447

Gene position: 514926-514186 (Counterclockwise)

Preceding gene: 15892448

Following gene: 15892446

Centisome position: 40.59

GC content: 35.49

Gene sequence:

>741_bases
ATGCGGCATCAGGACGTGGCTATAATTATCCCCTCAAGGCTAAGTTCAACTAGGCTTAAACAAAAACCGCTGCAGCTTAT
CGGCTCTATAACTTTAATCGAGCGGGTATTCAAACAAGTAAATCAAGCGGGCCTTGAGCATACATATGTTGCAACCGACT
CGGAAGAAATAGCAAGCGTTATTACAAAAGTCGGAGGAAAAGTAATATTCACGGATAGTGCTATCCCAACCGGTACTGAT
CGTACTTATGAAGCTTTTAAATTAATTCCAAATAATCAAAACATTAATTACATAGTTAATGTACAGGGAGATATGCCTTT
CATTGAACCTAGCTCTATTTTGAAAATTATAGAATATTTAAAAAACAGCAAATACGATGTTGTTACACCGATAGTAAAAG
TAGATAGGGAATCAGTGAAAGCTAGTAGTAATGTTACCGTAGCGGTTGACTCGGCGGGAACAGCATTGTATTTTTCGCGT
AGTCTTATTCCAAACGGTGCAGAAGAATTTTTATATCATGTAGGTATGTATGGTTTTCGCAAAAACGCTTTAGAAAAATT
TGTATCTCTTAAGCCAACTTTTTTAGAAAAAACAGAACGTTTAGAACAATTACGTGTCCTTGAAAACGGCATGACTATAG
GTACATGTTTAGTTGAGAATGTTCCTATTTCCGTAGATACGGAAGAAGACTTAAAAAAAGCAGTAAAATTTTACGAAAAT
ATTAGTAAACTAGGTTTATAA

Upstream 100 bases:

>100_bases
TCTTAAATATATTGCATATATTCAAAAATTATGTTTTACTTTATCGCCGAAAAAGGCTAATCTGTCAACAATTATTTTTT
AATTTAAACTTAGGAAGTTT

Downstream 100 bases:

>100_bases
TAATGGTACATTTCATTTTTGTTACCGGCGGCGTTGTTTCATCACTCGGTAAAGGTCTAACGGCAGCATCTCTTGCTATG
CTATTGCAAGCGAAAGGTTT

Product: 3-deoxy-manno-octulosonate cytidylyltransferase

Products: NA

Alternate protein names: CMP-2-keto-3-deoxyoctulosonic acid synthase; CKS; CMP-KDO synthase [H]

Number of amino acids: Translated: 246; Mature: 246

Protein sequence:

>246_residues
MRHQDVAIIIPSRLSSTRLKQKPLQLIGSITLIERVFKQVNQAGLEHTYVATDSEEIASVITKVGGKVIFTDSAIPTGTD
RTYEAFKLIPNNQNINYIVNVQGDMPFIEPSSILKIIEYLKNSKYDVVTPIVKVDRESVKASSNVTVAVDSAGTALYFSR
SLIPNGAEEFLYHVGMYGFRKNALEKFVSLKPTFLEKTERLEQLRVLENGMTIGTCLVENVPISVDTEEDLKKAVKFYEN
ISKLGL

Sequences:

>Translated_246_residues
MRHQDVAIIIPSRLSSTRLKQKPLQLIGSITLIERVFKQVNQAGLEHTYVATDSEEIASVITKVGGKVIFTDSAIPTGTD
RTYEAFKLIPNNQNINYIVNVQGDMPFIEPSSILKIIEYLKNSKYDVVTPIVKVDRESVKASSNVTVAVDSAGTALYFSR
SLIPNGAEEFLYHVGMYGFRKNALEKFVSLKPTFLEKTERLEQLRVLENGMTIGTCLVENVPISVDTEEDLKKAVKFYEN
ISKLGL
>Mature_246_residues
MRHQDVAIIIPSRLSSTRLKQKPLQLIGSITLIERVFKQVNQAGLEHTYVATDSEEIASVITKVGGKVIFTDSAIPTGTD
RTYEAFKLIPNNQNINYIVNVQGDMPFIEPSSILKIIEYLKNSKYDVVTPIVKVDRESVKASSNVTVAVDSAGTALYFSR
SLIPNGAEEFLYHVGMYGFRKNALEKFVSLKPTFLEKTERLEQLRVLENGMTIGTCLVENVPISVDTEEDLKKAVKFYEN
ISKLGL

Specific function: Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria [H]

COG id: COG1212

COG function: function code M; CMP-2-keto-3-deoxyoctulosonic acid synthetase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the kdsB family [H]

Homologues:

Organism=Escherichia coli, GI1787147, Length=239, Percent_Identity=35.5648535564854, Blast_Score=138, Evalue=4e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003329
- InterPro:   IPR004528 [H]

Pfam domain/function: PF02348 CTP_transf_3 [H]

EC number: =2.7.7.38 [H]

Molecular weight: Translated: 27476; Mature: 27476

Theoretical pI: Translated: 7.58; Mature: 7.58

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRHQDVAIIIPSRLSSTRLKQKPLQLIGSITLIERVFKQVNQAGLEHTYVATDSEEIASV
CCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCHHHHHHH
ITKVGGKVIFTDSAIPTGTDRTYEAFKLIPNNQNINYIVNVQGDMPFIEPSSILKIIEYL
HHHHCCEEEEECCCCCCCCCCCEEHEEECCCCCCCEEEEEECCCCCCCCHHHHHHHHHHH
KNSKYDVVTPIVKVDRESVKASSNVTVAVDSAGTALYFSRSLIPNGAEEFLYHVGMYGFR
HCCCCEEEHHHHHHHHHHHCCCCCEEEEEECCCCEEEEECCCCCCCHHHHHHHHHHHHHH
KNALEKFVSLKPTFLEKTERLEQLRVLENGMTIGTCLVENVPISVDTEEDLKKAVKFYEN
HHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCEEEHHHHCCCCCCCCCHHHHHHHHHHHHH
ISKLGL
HHHHCC
>Mature Secondary Structure
MRHQDVAIIIPSRLSSTRLKQKPLQLIGSITLIERVFKQVNQAGLEHTYVATDSEEIASV
CCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCHHHHHHH
ITKVGGKVIFTDSAIPTGTDRTYEAFKLIPNNQNINYIVNVQGDMPFIEPSSILKIIEYL
HHHHCCEEEEECCCCCCCCCCCEEHEEECCCCCCCEEEEEECCCCCCCCHHHHHHHHHHH
KNSKYDVVTPIVKVDRESVKASSNVTVAVDSAGTALYFSRSLIPNGAEEFLYHVGMYGFR
HCCCCEEEHHHHHHHHHHHCCCCCEEEEEECCCCEEEEECCCCCCCHHHHHHHHHHHHHH
KNALEKFVSLKPTFLEKTERLEQLRVLENGMTIGTCLVENVPISVDTEEDLKKAVKFYEN
HHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCEEEHHHHCCCCCCCCCHHHHHHHHHHHHH
ISKLGL
HHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA