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The map label for this gene is nuoA [H]

Identifier: 15892408

GI number: 15892408

Start: 480321

End: 480719

Strand: Reverse

Name: nuoA [H]

Synonym: RC0485

Alternate gene names: 15892408

Gene position: 480719-480321 (Counterclockwise)

Preceding gene: 15892409

Following gene: 15892407

Centisome position: 37.89

GC content: 30.33

Gene sequence:

>399_bases
ATGACGGAACAATATAATAAAAAACATATGCTACAAAACTCAGAACTTTTACAAGAATATCTACCGATTGCTATATTTTT
CGGTATTGCGGTATTGGTTTCCGGTTTAATAATGATTCTACCTAACCTATTATCGACAAAAAAATATAATAAAGATAAGC
TAGAACCTTATGAGTGCGGTTTTGAGCCTTTTAGCGATGCAAGATCAAAATTTGACATATGTTTTTACTTAGTTGCTATT
TTATTTATTATCTTTGATCTTGAAATTGCATTTTTAGTGCCTTGGGCTATTAGTCTTAATACGATAGGTAAAATAGGCTT
TTTCTCAATGATGTTTTTCTTATTCGTACTTATTATCGGATTCATATATGAATGGAAGAAAGGAGCTTTAGACTGGTAG

Upstream 100 bases:

>100_bases
TCATTAAATCTACGTCATTGCAAGCAGCCATAGGCTGCGTGGCAATCTCATCAAATATCCTGAGATTGCTTCGTCGCATT
ACTGTGCAATTCTTCTCGCA

Downstream 100 bases:

>100_bases
TAATATGAAAAATAATTTTTATCAAGAAGACGAATTATTAAGTAACGAGCTTTCTAATAGAGGATTCTTACTCACTAAAG
TTGATGACGTTATAGGCTGG

Product: NADH dehydrogenase subunit A

Products: NA

Alternate protein names: NADH dehydrogenase I subunit A; NDH-1 subunit A; NUO1 [H]

Number of amino acids: Translated: 132; Mature: 131

Protein sequence:

>132_residues
MTEQYNKKHMLQNSELLQEYLPIAIFFGIAVLVSGLIMILPNLLSTKKYNKDKLEPYECGFEPFSDARSKFDICFYLVAI
LFIIFDLEIAFLVPWAISLNTIGKIGFFSMMFFLFVLIIGFIYEWKKGALDW

Sequences:

>Translated_132_residues
MTEQYNKKHMLQNSELLQEYLPIAIFFGIAVLVSGLIMILPNLLSTKKYNKDKLEPYECGFEPFSDARSKFDICFYLVAI
LFIIFDLEIAFLVPWAISLNTIGKIGFFSMMFFLFVLIIGFIYEWKKGALDW
>Mature_131_residues
TEQYNKKHMLQNSELLQEYLPIAIFFGIAVLVSGLIMILPNLLSTKKYNKDKLEPYECGFEPFSDARSKFDICFYLVAIL
FIIFDLEIAFLVPWAISLNTIGKIGFFSMMFFLFVLIIGFIYEWKKGALDW

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG0838

COG function: function code C; NADH:ubiquinone oxidoreductase subunit 3 (chain A)

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I subunit 3 family [H]

Homologues:

Organism=Escherichia coli, GI1788625, Length=123, Percent_Identity=33.3333333333333, Blast_Score=82, Evalue=1e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023043
- InterPro:   IPR000440 [H]

Pfam domain/function: PF00507 Oxidored_q4 [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 15403; Mature: 15271

Theoretical pI: Translated: 5.11; Mature: 5.11

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTEQYNKKHMLQNSELLQEYLPIAIFFGIAVLVSGLIMILPNLLSTKKYNKDKLEPYECG
CCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHCC
FEPFSDARSKFDICFYLVAILFIIFDLEIAFLVPWAISLNTIGKIGFFSMMFFLFVLIIG
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FIYEWKKGALDW
HHHHHHHCCCCC
>Mature Secondary Structure 
TEQYNKKHMLQNSELLQEYLPIAIFFGIAVLVSGLIMILPNLLSTKKYNKDKLEPYECG
CCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHCC
FEPFSDARSKFDICFYLVAILFIIFDLEIAFLVPWAISLNTIGKIGFFSMMFFLFVLIIG
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FIYEWKKGALDW
HHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA