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The map label for this gene is frr [H]

Identifier: 15892120

GI number: 15892120

Start: 204380

End: 204940

Strand: Reverse

Name: frr [H]

Synonym: RC0197

Alternate gene names: 15892120

Gene position: 204940-204380 (Counterclockwise)

Preceding gene: 15892121

Following gene: 15892119

Centisome position: 16.15

GC content: 37.61

Gene sequence:

>561_bases
ATGGATAAAGAGCATTTAAAGAAAAACTTACAAGAAAAGATGGAGAAAGCTCTAAAAGTTTTAGATCATGAGCTTAAAGG
GCTACGTACCGGTAGAGCTTCAGTGAATTTACTTGATAGCGTAACCGTGGAAGCTTACGGGAGTAAAATGCCGCTTTCAC
AAGTTGCTTCTCTATCCACCCCTGATGCACGAACAATTAACGTGCAGGTTTGGGATAAATCTATGGTATCATCGGTAGAG
AAAGGAATTACGATAGCAAATCTTGGCTTAACTCCTGCAACGGACGGTCAATTAATCAGACTGCCGATACCGGCTTTAAC
TGAAGAAAGACGTACAGCACTGGTAAAACTTGCTCATAAATACGGTGAAGATACTAAAATTTCATTACGTAATATTAGAA
GAGACGGCAATGAAGCACTTAAAAAGCTAGAAAAGGATAACGTTATCGCAAAAGATGAGCATCATAGCTTATCTGAACAA
GTACAAAAGCTAACCGATGATTATAGTAGTAAAGTTGACTCGGTAATAAAACAAAAAGAACAAGAAATAATGACTGTTTG
A

Upstream 100 bases:

>100_bases
GACGGAAAAACCAATCTACACGGGAATTACATCGGGGACATTTCCTAATACATATAACAATGTCTCAATTCGTGTACTAA
TAATATATGGATAAATAAAG

Downstream 100 bases:

>100_bases
TTTTCTATGTCATTCCTGCTTTAGATTTGTTTCGTGGATACTAAATCATCATTGCGAAGAGGCCATTGTTGCGTGGACCG
GTAAAATCCACTGTGTCACC

Product: ribosome recycling factor

Products: NA

Alternate protein names: RRF; Ribosome-releasing factor [H]

Number of amino acids: Translated: 186; Mature: 186

Protein sequence:

>186_residues
MDKEHLKKNLQEKMEKALKVLDHELKGLRTGRASVNLLDSVTVEAYGSKMPLSQVASLSTPDARTINVQVWDKSMVSSVE
KGITIANLGLTPATDGQLIRLPIPALTEERRTALVKLAHKYGEDTKISLRNIRRDGNEALKKLEKDNVIAKDEHHSLSEQ
VQKLTDDYSSKVDSVIKQKEQEIMTV

Sequences:

>Translated_186_residues
MDKEHLKKNLQEKMEKALKVLDHELKGLRTGRASVNLLDSVTVEAYGSKMPLSQVASLSTPDARTINVQVWDKSMVSSVE
KGITIANLGLTPATDGQLIRLPIPALTEERRTALVKLAHKYGEDTKISLRNIRRDGNEALKKLEKDNVIAKDEHHSLSEQ
VQKLTDDYSSKVDSVIKQKEQEIMTV
>Mature_186_residues
MDKEHLKKNLQEKMEKALKVLDHELKGLRTGRASVNLLDSVTVEAYGSKMPLSQVASLSTPDARTINVQVWDKSMVSSVE
KGITIANLGLTPATDGQLIRLPIPALTEERRTALVKLAHKYGEDTKISLRNIRRDGNEALKKLEKDNVIAKDEHHSLSEQ
VQKLTDDYSSKVDSVIKQKEQEIMTV

Specific function: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another [H]

COG id: COG0233

COG function: function code J; Ribosome recycling factor

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RRF family [H]

Homologues:

Organism=Homo sapiens, GI20270317, Length=177, Percent_Identity=28.8135593220339, Blast_Score=71, Evalue=5e-13,
Organism=Homo sapiens, GI291042689, Length=149, Percent_Identity=30.8724832214765, Blast_Score=69, Evalue=3e-12,
Organism=Escherichia coli, GI1786368, Length=179, Percent_Identity=40.7821229050279, Blast_Score=154, Evalue=3e-39,

Paralogues:

None

Copy number: 840 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002661
- InterPro:   IPR015998 [H]

Pfam domain/function: PF01765 RRF [H]

EC number: NA

Molecular weight: Translated: 20812; Mature: 20812

Theoretical pI: Translated: 9.34; Mature: 9.34

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDKEHLKKNLQEKMEKALKVLDHELKGLRTGRASVNLLDSVTVEAYGSKMPLSQVASLST
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCHHHHHHCCC
PDARTINVQVWDKSMVSSVEKGITIANLGLTPATDGQLIRLPIPALTEERRTALVKLAHK
CCCEEEEEEECCHHHHHHHHHCCEEEECCCCCCCCCCEEEECCCHHHHHHHHHHHHHHHH
YGEDTKISLRNIRRDGNEALKKLEKDNVIAKDEHHSLSEQVQKLTDDYSSKVDSVIKQKE
HCCCCHHHHHHHHCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QEIMTV
HHHCCC
>Mature Secondary Structure
MDKEHLKKNLQEKMEKALKVLDHELKGLRTGRASVNLLDSVTVEAYGSKMPLSQVASLST
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCHHHHHHCCC
PDARTINVQVWDKSMVSSVEKGITIANLGLTPATDGQLIRLPIPALTEERRTALVKLAHK
CCCEEEEEEECCHHHHHHHHHCCEEEECCCCCCCCCCEEEECCCHHHHHHHHHHHHHHHH
YGEDTKISLRNIRRDGNEALKKLEKDNVIAKDEHHSLSEQVQKLTDDYSSKVDSVIKQKE
HCCCCHHHHHHHHCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QEIMTV
HHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA