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The map label for this gene is aatA [H]

Identifier: 15892043

GI number: 15892043

Start: 118092

End: 119297

Strand: Reverse

Name: aatA [H]

Synonym: RC0120

Alternate gene names: 15892043

Gene position: 119297-118092 (Counterclockwise)

Preceding gene: 15892044

Following gene: 15892042

Centisome position: 9.4

GC content: 33.83

Gene sequence:

>1206_bases
ATGTCAATTATTTCTACGAGGCTAAGTTCTATAAAACCGTCGCCGACCCTTGCAGTCGTTAAAAAAACTCTTGAACTTAA
AAAAGCGGGAGTTGATATTATCACACTCGGTGCCGGTGAGCCTGATTTTGATACGCCTGACAATATTAAGGAAGGAGCGA
TTAAAGCGATTAAAGACGGCTTTACTAAATATACTAACGTTGAGGGTATGCCTCTTTTAAAGCAAGCAATAAAAGACAAA
TTCAAACGTGAAAATAATATAGATTACGAACTTGATGAAATAATAGTAAGCACCGGCGGTAAACAAGTTATATATAATTT
GTTTATGGCATCTTTAGACCAAGGGGATGAGGTAATTATTCCAGCACCCTATTGGGTTTCATATCCTGATATGGTTGCAC
TTAGCACAGGAACACCTGTTTTTGTAAATTGCGGAATTGAAAATAACTTTAAATTAAGTGCAGAAGCTTTAGAACGTTCA
ATTACGGATAAAACTAAGTGGCTTATTATTAACTCACCTAGTAATCCAACAGGTGCAAGCTATAATTTTGAAGAACTAGA
AAATATTGCTAAAGTTTTAAGAAAATATTCACATGTAAACGTAATGTCCGATGATATTTACGAGCATATTACTTTTGATG
ATTTTAAATTTTATACATTAGCCCAAATAGCACCTGATTTAAAAAAGAGAATATTTACCGTAAACGGAGTATCTAAAGCT
TATTCTATGACGGGTTGGCGTATAGGCTACGGTGCAGGCTCTAAAACTTTGATTAAAGCAATGACTATTATTCAGTCGCA
AAGTACTTCAAACCCTTGTTCAATAAGTCAAATGGCTGCTATTGAAGCATTAAACGGTCCTCAAGATTATATAAAGCCTA
ATGCTTTAAATTGTCAAAAAAAGCGTGATCTTGCTTTATCAATTTTGAAAAGAGTAAAATATTTTGAATGCTATAAGCCG
GAAGGGGCGTTTTACTTATTTGTTAAATGCGATAAAATATTTGGGCATAAAACTAAATCAGGAACAATTATTGCAAATAG
TAATGATTTTGCCGAATATTTACTTGAAGAAGCAAAAGTTGCAGTAGTACCTGGTATCGCTTTCGGCTTAGAGGGATATT
TTAGAATCTCTTATGCTACTTCTATGGAAGAGCTAGAAAAAGCTTGTATTAGAATTGAGAAAACAATTGATGTCATTCCT
GCTTAA

Upstream 100 bases:

>100_bases
GTCACGTAGAATTAACCACGAACATAGACTAATATATTCTGTCAATACTAAACAAATTATAATATATAATTGTAGCTTTC
ATTTAATACGGACTCAAACT

Downstream 100 bases:

>100_bases
GGCTTTGCATGGATACCAAATCGTCATTGCGAGCAGCCATAGGCTGCGTGACAATTTCGTCAAATATCCTGAGATTGCTT
CGTCACTTACTTCGTAATTT

Product: aspartate aminotransferase

Products: NA

Alternate protein names: AspAT; Transaminase A [H]

Number of amino acids: Translated: 401; Mature: 400

Protein sequence:

>401_residues
MSIISTRLSSIKPSPTLAVVKKTLELKKAGVDIITLGAGEPDFDTPDNIKEGAIKAIKDGFTKYTNVEGMPLLKQAIKDK
FKRENNIDYELDEIIVSTGGKQVIYNLFMASLDQGDEVIIPAPYWVSYPDMVALSTGTPVFVNCGIENNFKLSAEALERS
ITDKTKWLIINSPSNPTGASYNFEELENIAKVLRKYSHVNVMSDDIYEHITFDDFKFYTLAQIAPDLKKRIFTVNGVSKA
YSMTGWRIGYGAGSKTLIKAMTIIQSQSTSNPCSISQMAAIEALNGPQDYIKPNALNCQKKRDLALSILKRVKYFECYKP
EGAFYLFVKCDKIFGHKTKSGTIIANSNDFAEYLLEEAKVAVVPGIAFGLEGYFRISYATSMEELEKACIRIEKTIDVIP
A

Sequences:

>Translated_401_residues
MSIISTRLSSIKPSPTLAVVKKTLELKKAGVDIITLGAGEPDFDTPDNIKEGAIKAIKDGFTKYTNVEGMPLLKQAIKDK
FKRENNIDYELDEIIVSTGGKQVIYNLFMASLDQGDEVIIPAPYWVSYPDMVALSTGTPVFVNCGIENNFKLSAEALERS
ITDKTKWLIINSPSNPTGASYNFEELENIAKVLRKYSHVNVMSDDIYEHITFDDFKFYTLAQIAPDLKKRIFTVNGVSKA
YSMTGWRIGYGAGSKTLIKAMTIIQSQSTSNPCSISQMAAIEALNGPQDYIKPNALNCQKKRDLALSILKRVKYFECYKP
EGAFYLFVKCDKIFGHKTKSGTIIANSNDFAEYLLEEAKVAVVPGIAFGLEGYFRISYATSMEELEKACIRIEKTIDVIP
A
>Mature_400_residues
SIISTRLSSIKPSPTLAVVKKTLELKKAGVDIITLGAGEPDFDTPDNIKEGAIKAIKDGFTKYTNVEGMPLLKQAIKDKF
KRENNIDYELDEIIVSTGGKQVIYNLFMASLDQGDEVIIPAPYWVSYPDMVALSTGTPVFVNCGIENNFKLSAEALERSI
TDKTKWLIINSPSNPTGASYNFEELENIAKVLRKYSHVNVMSDDIYEHITFDDFKFYTLAQIAPDLKKRIFTVNGVSKAY
SMTGWRIGYGAGSKTLIKAMTIIQSQSTSNPCSISQMAAIEALNGPQDYIKPNALNCQKKRDLALSILKRVKYFECYKPE
GAFYLFVKCDKIFGHKTKSGTIIANSNDFAEYLLEEAKVAVVPGIAFGLEGYFRISYATSMEELEKACIRIEKTIDVIPA

Specific function: Unknown

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI95147551, Length=343, Percent_Identity=28.2798833819242, Blast_Score=142, Evalue=4e-34,
Organism=Homo sapiens, GI169881279, Length=343, Percent_Identity=28.2798833819242, Blast_Score=142, Evalue=4e-34,
Organism=Homo sapiens, GI56713254, Length=367, Percent_Identity=27.7929155313352, Blast_Score=140, Evalue=2e-33,
Organism=Homo sapiens, GI56713256, Length=367, Percent_Identity=27.7929155313352, Blast_Score=140, Evalue=2e-33,
Organism=Homo sapiens, GI4507369, Length=316, Percent_Identity=27.5316455696203, Blast_Score=103, Evalue=3e-22,
Organism=Homo sapiens, GI169881281, Length=339, Percent_Identity=24.188790560472, Blast_Score=100, Evalue=4e-21,
Organism=Escherichia coli, GI1788722, Length=383, Percent_Identity=31.0704960835509, Blast_Score=155, Evalue=6e-39,
Organism=Escherichia coli, GI1788627, Length=382, Percent_Identity=28.0104712041885, Blast_Score=145, Evalue=4e-36,
Organism=Escherichia coli, GI1786816, Length=371, Percent_Identity=24.7978436657682, Blast_Score=124, Evalue=1e-29,
Organism=Caenorhabditis elegans, GI17567663, Length=375, Percent_Identity=26.1333333333333, Blast_Score=134, Evalue=6e-32,
Organism=Caenorhabditis elegans, GI71994476, Length=361, Percent_Identity=26.0387811634349, Blast_Score=127, Evalue=7e-30,
Organism=Caenorhabditis elegans, GI71994472, Length=361, Percent_Identity=26.0387811634349, Blast_Score=127, Evalue=7e-30,
Organism=Caenorhabditis elegans, GI17567369, Length=357, Percent_Identity=27.4509803921569, Blast_Score=124, Evalue=8e-29,
Organism=Caenorhabditis elegans, GI71981209, Length=337, Percent_Identity=24.0356083086053, Blast_Score=65, Evalue=7e-11,
Organism=Saccharomyces cerevisiae, GI6322401, Length=232, Percent_Identity=29.7413793103448, Blast_Score=110, Evalue=4e-25,
Organism=Saccharomyces cerevisiae, GI6320317, Length=342, Percent_Identity=23.3918128654971, Blast_Score=80, Evalue=7e-16,
Organism=Saccharomyces cerevisiae, GI6323118, Length=340, Percent_Identity=23.8235294117647, Blast_Score=77, Evalue=4e-15,
Organism=Drosophila melanogaster, GI28573069, Length=391, Percent_Identity=25.3196930946292, Blast_Score=125, Evalue=6e-29,
Organism=Drosophila melanogaster, GI24646114, Length=391, Percent_Identity=25.3196930946292, Blast_Score=125, Evalue=6e-29,
Organism=Drosophila melanogaster, GI28573067, Length=391, Percent_Identity=25.3196930946292, Blast_Score=125, Evalue=6e-29,
Organism=Drosophila melanogaster, GI28573065, Length=391, Percent_Identity=25.3196930946292, Blast_Score=125, Evalue=6e-29,
Organism=Drosophila melanogaster, GI18859735, Length=392, Percent_Identity=22.1938775510204, Blast_Score=104, Evalue=1e-22,
Organism=Drosophila melanogaster, GI24641770, Length=395, Percent_Identity=25.0632911392405, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24641760, Length=395, Percent_Identity=25.0632911392405, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24641768, Length=395, Percent_Identity=25.0632911392405, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24641766, Length=395, Percent_Identity=25.0632911392405, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24641764, Length=395, Percent_Identity=25.0632911392405, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI45551451, Length=395, Percent_Identity=25.0632911392405, Blast_Score=67, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001176
- InterPro:   IPR004839
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.1 [H]

Molecular weight: Translated: 44577; Mature: 44446

Theoretical pI: Translated: 7.30; Mature: 7.30

Prosite motif: PS00105 AA_TRANSFER_CLASS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSIISTRLSSIKPSPTLAVVKKTLELKKAGVDIITLGAGEPDFDTPDNIKEGAIKAIKDG
CCHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCHHHHHHHHHHHC
FTKYTNVEGMPLLKQAIKDKFKRENNIDYELDEIIVSTGGKQVIYNLFMASLDQGDEVII
CHHHCCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHCCCCHHHHHHHHHHHCCCCCEEEE
PAPYWVSYPDMVALSTGTPVFVNCGIENNFKLSAEALERSITDKTKWLIINSPSNPTGAS
CCCCEECCCCEEEEECCCCEEEECCCCCCCEEEHHHHHHHHCCCEEEEEEECCCCCCCCC
YNFEELENIAKVLRKYSHVNVMSDDIYEHITFDDFKFYTLAQIAPDLKKRIFTVNGVSKA
CCHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHEEEECCCHHH
YSMTGWRIGYGAGSKTLIKAMTIIQSQSTSNPCSISQMAAIEALNGPQDYIKPNALNCQK
HHCCCEEEEECCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCCHHHCCCCCCCCHH
KRDLALSILKRVKYFECYKPEGAFYLFVKCDKIFGHKTKSGTIIANSNDFAEYLLEEAKV
HHHHHHHHHHHHHHHEEECCCCCEEEEEEEEHHHCCCCCCCEEEECCCHHHHHHHHHCCE
AVVPGIAFGLEGYFRISYATSMEELEKACIRIEKTIDVIPA
EEECCHHHCCCCEEEEEEHHCHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
SIISTRLSSIKPSPTLAVVKKTLELKKAGVDIITLGAGEPDFDTPDNIKEGAIKAIKDG
CHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCHHHHHHHHHHHC
FTKYTNVEGMPLLKQAIKDKFKRENNIDYELDEIIVSTGGKQVIYNLFMASLDQGDEVII
CHHHCCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHCCCCHHHHHHHHHHHCCCCCEEEE
PAPYWVSYPDMVALSTGTPVFVNCGIENNFKLSAEALERSITDKTKWLIINSPSNPTGAS
CCCCEECCCCEEEEECCCCEEEECCCCCCCEEEHHHHHHHHCCCEEEEEEECCCCCCCCC
YNFEELENIAKVLRKYSHVNVMSDDIYEHITFDDFKFYTLAQIAPDLKKRIFTVNGVSKA
CCHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHEEEECCCHHH
YSMTGWRIGYGAGSKTLIKAMTIIQSQSTSNPCSISQMAAIEALNGPQDYIKPNALNCQK
HHCCCEEEEECCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCCHHHCCCCCCCCHH
KRDLALSILKRVKYFECYKPEGAFYLFVKCDKIFGHKTKSGTIIANSNDFAEYLLEEAKV
HHHHHHHHHHHHHHHEEECCCCCEEEEEEEEHHHCCCCCCCEEEECCCHHHHHHHHHCCE
AVVPGIAFGLEGYFRISYATSMEELEKACIRIEKTIDVIPA
EEECCHHHCCCCEEEEEEHHCHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA