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The map label for this gene is hesB1 [C]

Identifier: 15892016

GI number: 15892016

Start: 85658

End: 85990

Strand: Reverse

Name: hesB1 [C]

Synonym: RC0093

Alternate gene names: 15892016

Gene position: 85990-85658 (Counterclockwise)

Preceding gene: 15892021

Following gene: 15892003

Centisome position: 6.78

GC content: 34.53

Gene sequence:

>333_bases
GTGACGATAACAATTACGGATAGAGCTTTTGAACGGGTTTGCGAGTTAGTAAAGCTAGAAAAAGATAAGAATTTAGTACT
GCGAATTTCGGTTGATAGCGGCGGTTGCTCAGGACTTATGTATAATTACGAACTAGTCTCAAAAGATAATATAGAGCAAG
ATGATTATGTCATTACTAAACATAATGCTACAATTATTATTGATCCTATCTCTCAAAAATTTATACTAGATTGCACTCTT
GATTTTATAGAAGAACTAGGCAGTTCATATTTCAACGTTAGTAATCCGCAAGCTAAAGCAAAATGCGGCTGCGGTAATTC
TTTCTCAGTGTAA

Upstream 100 bases:

>100_bases
GGCTGCTCGCAATGCCGATTGGGTATCCACACAACAAACCAACTTGAAAAATATCAAGATATACTATATAATTTATGAGA
CTTTTACAAGGTAATTTTAA

Downstream 100 bases:

>100_bases
ATGCAAGTATTGTGAGTGGACATTGTTATTAGAATGCCGATGTCATTCCTGCAACAGCAGCAATGACATCGCAACGTCAA
ACTTTTAATGTTAATCATTA

Product: hesB protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 110; Mature: 109

Protein sequence:

>110_residues
MTITITDRAFERVCELVKLEKDKNLVLRISVDSGGCSGLMYNYELVSKDNIEQDDYVITKHNATIIIDPISQKFILDCTL
DFIEELGSSYFNVSNPQAKAKCGCGNSFSV

Sequences:

>Translated_110_residues
MTITITDRAFERVCELVKLEKDKNLVLRISVDSGGCSGLMYNYELVSKDNIEQDDYVITKHNATIIIDPISQKFILDCTL
DFIEELGSSYFNVSNPQAKAKCGCGNSFSV
>Mature_109_residues
TITITDRAFERVCELVKLEKDKNLVLRISVDSGGCSGLMYNYELVSKDNIEQDDYVITKHNATIIIDPISQKFILDCTLD
FIEELGSSYFNVSNPQAKAKCGCGNSFSV

Specific function: Unknown

COG id: COG0316

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hesB/iscA family [H]

Homologues:

Organism=Homo sapiens, GI160420328, Length=109, Percent_Identity=36.697247706422, Blast_Score=71, Evalue=2e-13,
Organism=Escherichia coli, GI1786351, Length=110, Percent_Identity=36.3636363636364, Blast_Score=88, Evalue=1e-19,
Organism=Escherichia coli, GI1788877, Length=110, Percent_Identity=35.4545454545455, Blast_Score=70, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI71998452, Length=108, Percent_Identity=37.962962962963, Blast_Score=72, Evalue=7e-14,
Organism=Caenorhabditis elegans, GI193209025, Length=109, Percent_Identity=34.8623853211009, Blast_Score=64, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI25146411, Length=109, Percent_Identity=34.8623853211009, Blast_Score=64, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6325324, Length=130, Percent_Identity=32.3076923076923, Blast_Score=65, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24649697, Length=85, Percent_Identity=36.4705882352941, Blast_Score=63, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000361
- InterPro:   IPR016092
- InterPro:   IPR017870 [H]

Pfam domain/function: PF01521 Fe-S_biosyn [H]

EC number: NA

Molecular weight: Translated: 12293; Mature: 12162

Theoretical pI: Translated: 4.49; Mature: 4.49

Prosite motif: PS01152 HESB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.5 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
6.4 %Cys+Met (Translated Protein)
4.6 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTITITDRAFERVCELVKLEKDKNLVLRISVDSGGCSGLMYNYELVSKDNIEQDDYVITK
CEEEECHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCEEEEEEEEECCCCCCCCCEEEEE
HNATIIIDPISQKFILDCTLDFIEELGSSYFNVSNPQAKAKCGCGNSFSV
CCCEEEECCCCCEEEEEEHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
TITITDRAFERVCELVKLEKDKNLVLRISVDSGGCSGLMYNYELVSKDNIEQDDYVITK
EEEECHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCEEEEEEEEECCCCCCCCCEEEEE
HNATIIIDPISQKFILDCTLDFIEELGSSYFNVSNPQAKAKCGCGNSFSV
CCCEEEECCCCCEEEEEEHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9823893 [H]