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The map label for this gene is argD [H]

Identifier: 158425652

GI number: 158425652

Start: 4598035

End: 4599243

Strand: Reverse

Name: argD [H]

Synonym: AZC_4028

Alternate gene names: 158425652

Gene position: 4599243-4598035 (Counterclockwise)

Preceding gene: 158425654

Following gene: 158425651

Centisome position: 85.65

GC content: 69.07

Gene sequence:

>1209_bases
GTGATATCCCCCGTTCTGCCGACCTATGCACGCATCAACCTGGAATTCGAGCGGGGAGAGGGCTGCTGGCTCGTGACGAC
GGACGGGCGACGTTATCTCGACTTCACCGCCGGCATCGCGGTCAATGTGCTGGGTCACGCCAATCCCTATCTGGCGCAGG
CCCTGACCGAGCAGGCGGGCAAGCTCTGGCACACCTCGAACCTGTTCCGCATCGCCGGCGGCGAGCGGCTGGCCGAGCGC
CTCACGCAGGCGACCTTCGCCGATACGGTCTTCTTCACCAATTCCGGTGCGGAAGCGCTGGAGTGCGCCATCAAGATGGC
GCGCAAATACCAGTATGTCTCCGGCCATCCCGAGCGGAACCGCCTCATCGCCTTCGAGGGCGCCTTCCACGGACGCACGC
TCGCGACCATCGCCGCCGGCGGCAATGCCAAGTATCTCGAAGGCTTCGGCCCCGAGCTGCCGGGCTTCGACCATGTGCCC
TTCGGCGATCTGGAGGCGGTGAAGGCGGCCATCGGCCCCGCCACCGCCGGCATCCTGCTGGAACCCATCCAGGGCGAGGG
CGGTGTGCGCGTGCCGCCGTCCGGCTTCCTCGCCGCCCTGCGGGCGCTGTGCGACGAGCACGGCCTGCTGCTGGTGCTGG
ACGAGGTGCAGAGCGGCGTCGGCCGCACCGGCAAGCTGTTCGCCCACGAATGGGCGGGCGTCACGCCGGACATCATGTCG
GTCGCCAAGGGCATCGGCGGCGGCTTCCCCATGGGCGCCTGCCTCGCCACGGAAGAAGCGGCCAAGGGCATGACGCTGGG
CACCCACGGCTCCACCTATGGCGGCAACCCGCTCGCCATGGCGGTGGGCAATGCGGTGCTGGACAAGGTTCTGGAGCCGT
CCTTCCTGGAGCATGTGAACCAGATCAGCCTGCGCTTCACGCAGCTTCTGGCCGGCGTGAAGGACCGCCATCCCGGCGTC
ATCGCCGAGGTGCGCGGCCAGGGCCTGCTGCTCGGCCTGCGCGCCAATGTGCCGGCGGGCGATCTCGTGGTGGCGCTGCG
CGAGGAGGGCCTGCTGGCCCCCGGCGCCGGCGACAATGTTGTGCGCCTCCTGCCGCCTCTGGTGGTCAGCGAGGAAGAAG
TGAAGCTTGCGGCGGAAAAGATCGAGGCGGCTTGCCGGCGGATCGAGGACGGGCTTGCAGCCGCGCCGGTGAAGGGGGCC
GCCGAATGA

Upstream 100 bases:

>100_bases
ATAGCTAGAATCACCCATGTCGGGCTGCCCCGCTTGGGCGGCCTTTTTCCGTTTGTCCCTGCGCCACTCCGGCGCTCAAC
CCTCGTGAGGAGGGGTTCCC

Downstream 100 bases:

>100_bases
GCGGGAATGGTGTGCGTCACTTTCTGGATCTGACGGATCTGGAGGCAGTGGACCTGCGCGGGGTGCTGGAGCTCTCCAAG
CAGCTGAAGGCCAAGCGCAA

Product: acetylornithine and succinylornithine aminotransferase

Products: NA

Alternate protein names: ACOAT [H]

Number of amino acids: Translated: 402; Mature: 402

Protein sequence:

>402_residues
MISPVLPTYARINLEFERGEGCWLVTTDGRRYLDFTAGIAVNVLGHANPYLAQALTEQAGKLWHTSNLFRIAGGERLAER
LTQATFADTVFFTNSGAEALECAIKMARKYQYVSGHPERNRLIAFEGAFHGRTLATIAAGGNAKYLEGFGPELPGFDHVP
FGDLEAVKAAIGPATAGILLEPIQGEGGVRVPPSGFLAALRALCDEHGLLLVLDEVQSGVGRTGKLFAHEWAGVTPDIMS
VAKGIGGGFPMGACLATEEAAKGMTLGTHGSTYGGNPLAMAVGNAVLDKVLEPSFLEHVNQISLRFTQLLAGVKDRHPGV
IAEVRGQGLLLGLRANVPAGDLVVALREEGLLAPGAGDNVVRLLPPLVVSEEEVKLAAEKIEAACRRIEDGLAAAPVKGA
AE

Sequences:

>Translated_402_residues
MISPVLPTYARINLEFERGEGCWLVTTDGRRYLDFTAGIAVNVLGHANPYLAQALTEQAGKLWHTSNLFRIAGGERLAER
LTQATFADTVFFTNSGAEALECAIKMARKYQYVSGHPERNRLIAFEGAFHGRTLATIAAGGNAKYLEGFGPELPGFDHVP
FGDLEAVKAAIGPATAGILLEPIQGEGGVRVPPSGFLAALRALCDEHGLLLVLDEVQSGVGRTGKLFAHEWAGVTPDIMS
VAKGIGGGFPMGACLATEEAAKGMTLGTHGSTYGGNPLAMAVGNAVLDKVLEPSFLEHVNQISLRFTQLLAGVKDRHPGV
IAEVRGQGLLLGLRANVPAGDLVVALREEGLLAPGAGDNVVRLLPPLVVSEEEVKLAAEKIEAACRRIEDGLAAAPVKGA
AE
>Mature_402_residues
MISPVLPTYARINLEFERGEGCWLVTTDGRRYLDFTAGIAVNVLGHANPYLAQALTEQAGKLWHTSNLFRIAGGERLAER
LTQATFADTVFFTNSGAEALECAIKMARKYQYVSGHPERNRLIAFEGAFHGRTLATIAAGGNAKYLEGFGPELPGFDHVP
FGDLEAVKAAIGPATAGILLEPIQGEGGVRVPPSGFLAALRALCDEHGLLLVLDEVQSGVGRTGKLFAHEWAGVTPDIMS
VAKGIGGGFPMGACLATEEAAKGMTLGTHGSTYGGNPLAMAVGNAVLDKVLEPSFLEHVNQISLRFTQLLAGVKDRHPGV
IAEVRGQGLLLGLRANVPAGDLVVALREEGLLAPGAGDNVVRLLPPLVVSEEEVKLAAEKIEAACRRIEDGLAAAPVKGA
AE

Specific function: Catalyzes The Transmination Of N(2)-Succinylornithine And Alpha-Ketoglutarate Into N(2)-Succinylglutamate Semialdehyde And Glutamate. Can Also Act As A Acetylornithine Aminotransferase. [C]

COG id: COG4992

COG function: function code E; Ornithine/acetylornithine aminotransferase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily [H]

Homologues:

Organism=Homo sapiens, GI4557809, Length=383, Percent_Identity=35.7702349869452, Blast_Score=230, Evalue=2e-60,
Organism=Homo sapiens, GI284507298, Length=296, Percent_Identity=37.8378378378378, Blast_Score=193, Evalue=2e-49,
Organism=Homo sapiens, GI13994255, Length=442, Percent_Identity=30.5429864253394, Blast_Score=174, Evalue=2e-43,
Organism=Homo sapiens, GI37574042, Length=431, Percent_Identity=26.9141531322506, Blast_Score=136, Evalue=4e-32,
Organism=Homo sapiens, GI24119277, Length=423, Percent_Identity=26.9503546099291, Blast_Score=132, Evalue=5e-31,
Organism=Homo sapiens, GI226442705, Length=431, Percent_Identity=26.6821345707657, Blast_Score=128, Evalue=8e-30,
Organism=Homo sapiens, GI226442709, Length=396, Percent_Identity=27.5252525252525, Blast_Score=128, Evalue=1e-29,
Organism=Homo sapiens, GI188536080, Length=427, Percent_Identity=25.5269320843091, Blast_Score=101, Evalue=1e-21,
Organism=Homo sapiens, GI38679950, Length=427, Percent_Identity=25.5269320843091, Blast_Score=101, Evalue=1e-21,
Organism=Homo sapiens, GI38679946, Length=427, Percent_Identity=25.5269320843091, Blast_Score=101, Evalue=1e-21,
Organism=Escherichia coli, GI1788044, Length=388, Percent_Identity=46.9072164948454, Blast_Score=335, Evalue=2e-93,
Organism=Escherichia coli, GI1789759, Length=388, Percent_Identity=44.8453608247423, Blast_Score=322, Evalue=3e-89,
Organism=Escherichia coli, GI145693181, Length=396, Percent_Identity=37.8787878787879, Blast_Score=231, Evalue=9e-62,
Organism=Escherichia coli, GI1787560, Length=415, Percent_Identity=36.6265060240964, Blast_Score=201, Evalue=7e-53,
Organism=Escherichia coli, GI1789016, Length=400, Percent_Identity=35.25, Blast_Score=200, Evalue=2e-52,
Organism=Escherichia coli, GI1786991, Length=418, Percent_Identity=30.1435406698565, Blast_Score=138, Evalue=5e-34,
Organism=Escherichia coli, GI1786349, Length=312, Percent_Identity=31.4102564102564, Blast_Score=132, Evalue=4e-32,
Organism=Caenorhabditis elegans, GI25144271, Length=380, Percent_Identity=36.3157894736842, Blast_Score=240, Evalue=8e-64,
Organism=Caenorhabditis elegans, GI32564660, Length=452, Percent_Identity=30.5309734513274, Blast_Score=186, Evalue=1e-47,
Organism=Caenorhabditis elegans, GI25144274, Length=260, Percent_Identity=38.4615384615385, Blast_Score=180, Evalue=9e-46,
Organism=Caenorhabditis elegans, GI71992977, Length=408, Percent_Identity=26.9607843137255, Blast_Score=125, Evalue=5e-29,
Organism=Caenorhabditis elegans, GI17541228, Length=451, Percent_Identity=23.7250554323725, Blast_Score=97, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI71981843, Length=163, Percent_Identity=33.1288343558282, Blast_Score=95, Evalue=8e-20,
Organism=Saccharomyces cerevisiae, GI6324432, Length=394, Percent_Identity=37.0558375634518, Blast_Score=262, Evalue=6e-71,
Organism=Saccharomyces cerevisiae, GI6323470, Length=400, Percent_Identity=34.75, Blast_Score=229, Evalue=6e-61,
Organism=Saccharomyces cerevisiae, GI6324386, Length=376, Percent_Identity=25.7978723404255, Blast_Score=99, Evalue=1e-21,
Organism=Saccharomyces cerevisiae, GI6321456, Length=425, Percent_Identity=23.7647058823529, Blast_Score=97, Evalue=5e-21,
Organism=Drosophila melanogaster, GI21357415, Length=381, Percent_Identity=34.6456692913386, Blast_Score=221, Evalue=6e-58,
Organism=Drosophila melanogaster, GI161085790, Length=440, Percent_Identity=31.3636363636364, Blast_Score=185, Evalue=6e-47,
Organism=Drosophila melanogaster, GI28574759, Length=438, Percent_Identity=30.8219178082192, Blast_Score=181, Evalue=9e-46,
Organism=Drosophila melanogaster, GI21356575, Length=424, Percent_Identity=28.7735849056604, Blast_Score=130, Evalue=1e-30,
Organism=Drosophila melanogaster, GI281366494, Length=440, Percent_Identity=23.6363636363636, Blast_Score=98, Evalue=1e-20,
Organism=Drosophila melanogaster, GI24667139, Length=440, Percent_Identity=23.6363636363636, Blast_Score=98, Evalue=1e-20,
Organism=Drosophila melanogaster, GI24667143, Length=440, Percent_Identity=23.6363636363636, Blast_Score=98, Evalue=1e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004636
- InterPro:   IPR005814
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00202 Aminotran_3 [H]

EC number: =2.6.1.11 [H]

Molecular weight: Translated: 42268; Mature: 42268

Theoretical pI: Translated: 5.62; Mature: 5.62

Prosite motif: PS00600 AA_TRANSFER_CLASS_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MISPVLPTYARINLEFERGEGCWLVTTDGRRYLDFTAGIAVNVLGHANPYLAQALTEQAG
CCCCCCCCEEEEEEEEECCCEEEEEECCCCEEEEEECCEEEEEECCCCHHHHHHHHHHHH
KLWHTSNLFRIAGGERLAERLTQATFADTVFFTNSGAEALECAIKMARKYQYVSGHPERN
CEEECCCEEEECCHHHHHHHHHHHHHHHEEEEECCCHHHHHHHHHHHHHHHHHCCCCCCC
RLIAFEGAFHGRTLATIAAGGNAKYLEGFGPELPGFDHVPFGDLEAVKAAIGPATAGILL
EEEEEECCCCCCEEEEEEECCCCHHHCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCEEE
EPIQGEGGVRVPPSGFLAALRALCDEHGLLLVLDEVQSGVGRTGKLFAHEWAGVTPDIMS
EEECCCCCEECCCHHHHHHHHHHHCCCCEEEEEEHHHCCCCCCCCEEEHHCCCCCHHHHH
VAKGIGGGFPMGACLATEEAAKGMTLGTHGSTYGGNPLAMAVGNAVLDKVLEPSFLEHVN
HHHHCCCCCCCHHHHHHHHHHCCCEECCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHH
QISLRFTQLLAGVKDRHPGVIAEVRGQGLLLGLRANVPAGDLVVALREEGLLAPGAGDNV
HHHHHHHHHHHCCCCCCCCEEEEECCCEEEEEEECCCCCCCEEEEEECCCEECCCCCCCH
VRLLPPLVVSEEEVKLAAEKIEAACRRIEDGLAAAPVKGAAE
HHHCCCHHCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure
MISPVLPTYARINLEFERGEGCWLVTTDGRRYLDFTAGIAVNVLGHANPYLAQALTEQAG
CCCCCCCCEEEEEEEEECCCEEEEEECCCCEEEEEECCEEEEEECCCCHHHHHHHHHHHH
KLWHTSNLFRIAGGERLAERLTQATFADTVFFTNSGAEALECAIKMARKYQYVSGHPERN
CEEECCCEEEECCHHHHHHHHHHHHHHHEEEEECCCHHHHHHHHHHHHHHHHHCCCCCCC
RLIAFEGAFHGRTLATIAAGGNAKYLEGFGPELPGFDHVPFGDLEAVKAAIGPATAGILL
EEEEEECCCCCCEEEEEEECCCCHHHCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCEEE
EPIQGEGGVRVPPSGFLAALRALCDEHGLLLVLDEVQSGVGRTGKLFAHEWAGVTPDIMS
EEECCCCCEECCCHHHHHHHHHHHCCCCEEEEEEHHHCCCCCCCCEEEHHCCCCCHHHHH
VAKGIGGGFPMGACLATEEAAKGMTLGTHGSTYGGNPLAMAVGNAVLDKVLEPSFLEHVN
HHHHCCCCCCCHHHHHHHHHHCCCEECCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHH
QISLRFTQLLAGVKDRHPGVIAEVRGQGLLLGLRANVPAGDLVVALREEGLLAPGAGDNV
HHHHHHHHHHHCCCCCCCCEEEEECCCEEEEEEECCCCCCCEEEEEECCCEECCCCCCCH
VRLLPPLVVSEEEVKLAAEKIEAACRRIEDGLAAAPVKGAAE
HHHCCCHHCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11756688 [H]