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The map label for this gene is argF [H]

Identifier: 158425651

GI number: 158425651

Start: 4597109

End: 4598038

Strand: Reverse

Name: argF [H]

Synonym: AZC_4027

Alternate gene names: 158425651

Gene position: 4598038-4597109 (Counterclockwise)

Preceding gene: 158425652

Following gene: 158425650

Centisome position: 85.63

GC content: 65.05

Gene sequence:

>930_bases
ATGAGCGGGAATGGTGTGCGTCACTTTCTGGATCTGACGGATCTGGAGGCAGTGGACCTGCGCGGGGTGCTGGAGCTCTC
CAAGCAGCTGAAGGCCAAGCGCAAGGCGGGAACCGAGGAGAAGCCGCTGGCGGGCAAGTCGCTCGCCATGGTCTTCGACA
AGCCCTCGACCCGCACGCGCGTGTCGTTCGATCTGGCCATGCGCCAGCTCGGCGGCGAGACCATCATGCTCACGGGCGCG
GAAATGCAGCTCGGGCGCGGCGAAAGCATCGCCGACACCGCCCGCGTGCTGTCGCGTTTCGTGGATGCGATCATGATCCG
CATCCTGAGCCATGAGGACCTGCTGGAACTGGCGAAATTCGCCACCGTGCCGGTCATCAACGGCCTCACCCGCGTGTCCC
ATCCCTGTCAGGTGATGGCCGATGTGCTCACCTTCGAGGAGCACAAGGGCAGCATCGAGGGGCGCAGCGTGGCCTGGACC
GGCGACGCCAACAATGTGCTCGCCTCGTGGGTTCACGCGGCGGCGCAATTTGACTTCACCATCAATGTCGCGACGCCCAA
GGAGCTGTCTCCGCGTCAGGCCCTGAAGGAGTTCGTCAAGCGCACGCAGGCCAAGGTGCGCTTCATGCGCGATCCGGAAG
AGGCGGTGGAAGGCGTCGATTGCGTCATCACCGACACCTGGGTCTCCATGGGCGACAAGGAGGCCGAGCGCCGTCACAAC
CTCTTGAAGCCCTATCAGGTGAACGCCAAGCTCATGGCGCGCGCCGCGCCCGACGCCATATTCATGCATTGCCTGCCCGC
CCATCGCGGCGAGGAGGTGACGGATGAGGTGATGGACGGCCCGCAGTCGGTGGTGTTCGACGAGGCGGAGAACCGTCTGC
ACGCCCAGAAGGGCATCCTCGCCTGGTGCCTGGAGAAGGCGAGCGCCTGA

Upstream 100 bases:

>100_bases
TCAGCGAGGAAGAAGTGAAGCTTGCGGCGGAAAAGATCGAGGCGGCTTGCCGGCGGATCGAGGACGGGCTTGCAGCCGCG
CCGGTGAAGGGGGCCGCCGA

Downstream 100 bases:

>100_bases
TCCCCTCGCTTGGCCGGCCCCGCATGGGGCCTGTAAGGCCGAGTGGACGGACGGGTGCAAAGAGCGCAATCCTTGCGGCC
CCGGTCCATGACCGGGGCCG

Product: ornithine carbamoyltransferase

Products: NA

Alternate protein names: OTCase [H]

Number of amino acids: Translated: 309; Mature: 308

Protein sequence:

>309_residues
MSGNGVRHFLDLTDLEAVDLRGVLELSKQLKAKRKAGTEEKPLAGKSLAMVFDKPSTRTRVSFDLAMRQLGGETIMLTGA
EMQLGRGESIADTARVLSRFVDAIMIRILSHEDLLELAKFATVPVINGLTRVSHPCQVMADVLTFEEHKGSIEGRSVAWT
GDANNVLASWVHAAAQFDFTINVATPKELSPRQALKEFVKRTQAKVRFMRDPEEAVEGVDCVITDTWVSMGDKEAERRHN
LLKPYQVNAKLMARAAPDAIFMHCLPAHRGEEVTDEVMDGPQSVVFDEAENRLHAQKGILAWCLEKASA

Sequences:

>Translated_309_residues
MSGNGVRHFLDLTDLEAVDLRGVLELSKQLKAKRKAGTEEKPLAGKSLAMVFDKPSTRTRVSFDLAMRQLGGETIMLTGA
EMQLGRGESIADTARVLSRFVDAIMIRILSHEDLLELAKFATVPVINGLTRVSHPCQVMADVLTFEEHKGSIEGRSVAWT
GDANNVLASWVHAAAQFDFTINVATPKELSPRQALKEFVKRTQAKVRFMRDPEEAVEGVDCVITDTWVSMGDKEAERRHN
LLKPYQVNAKLMARAAPDAIFMHCLPAHRGEEVTDEVMDGPQSVVFDEAENRLHAQKGILAWCLEKASA
>Mature_308_residues
SGNGVRHFLDLTDLEAVDLRGVLELSKQLKAKRKAGTEEKPLAGKSLAMVFDKPSTRTRVSFDLAMRQLGGETIMLTGAE
MQLGRGESIADTARVLSRFVDAIMIRILSHEDLLELAKFATVPVINGLTRVSHPCQVMADVLTFEEHKGSIEGRSVAWTG
DANNVLASWVHAAAQFDFTINVATPKELSPRQALKEFVKRTQAKVRFMRDPEEAVEGVDCVITDTWVSMGDKEAERRHNL
LKPYQVNAKLMARAAPDAIFMHCLPAHRGEEVTDEVMDGPQSVVFDEAENRLHAQKGILAWCLEKASA

Specific function: Arginine biosynthesis; sixth step. [C]

COG id: COG0078

COG function: function code E; Ornithine carbamoyltransferase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATCase/OTCase family [H]

Homologues:

Organism=Homo sapiens, GI38788445, Length=292, Percent_Identity=42.8082191780822, Blast_Score=233, Evalue=1e-61,
Organism=Homo sapiens, GI18105007, Length=274, Percent_Identity=28.4671532846715, Blast_Score=100, Evalue=2e-21,
Organism=Escherichia coli, GI1790703, Length=334, Percent_Identity=38.9221556886228, Blast_Score=223, Evalue=2e-59,
Organism=Escherichia coli, GI1786469, Length=322, Percent_Identity=38.5093167701863, Blast_Score=209, Evalue=2e-55,
Organism=Escherichia coli, GI2367364, Length=308, Percent_Identity=29.5454545454545, Blast_Score=99, Evalue=3e-22,
Organism=Caenorhabditis elegans, GI193204318, Length=328, Percent_Identity=27.1341463414634, Blast_Score=91, Evalue=6e-19,
Organism=Saccharomyces cerevisiae, GI6322373, Length=311, Percent_Identity=34.4051446945338, Blast_Score=187, Evalue=2e-48,
Organism=Saccharomyces cerevisiae, GI6322331, Length=308, Percent_Identity=26.6233766233766, Blast_Score=104, Evalue=2e-23,
Organism=Drosophila melanogaster, GI24642586, Length=309, Percent_Identity=27.831715210356, Blast_Score=112, Evalue=2e-25,

Paralogues:

None

Copy number: 140 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2066 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006132
- InterPro:   IPR006130
- InterPro:   IPR006131
- InterPro:   IPR002292 [H]

Pfam domain/function: PF00185 OTCace; PF02729 OTCace_N [H]

EC number: =2.1.3.3 [H]

Molecular weight: Translated: 34178; Mature: 34046

Theoretical pI: Translated: 6.43; Mature: 6.43

Prosite motif: PS00097 CARBAMOYLTRANSFERASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSGNGVRHFLDLTDLEAVDLRGVLELSKQLKAKRKAGTEEKPLAGKSLAMVFDKPSTRTR
CCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEECCCCCCHH
VSFDLAMRQLGGETIMLTGAEMQLGRGESIADTARVLSRFVDAIMIRILSHEDLLELAKF
HHHHHHHHHHCCCEEEEECCCEECCCCCCHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHH
ATVPVINGLTRVSHPCQVMADVLTFEEHKGSIEGRSVAWTGDANNVLASWVHAAAQFDFT
HHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCEEEEECCCHHHHHHHHHHHHHEEEE
INVATPKELSPRQALKEFVKRTQAKVRFMRDPEEAVEGVDCVITDTWVSMGDKEAERRHN
EEECCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHCCCEEEEEHHHHHCCCHHHHHHHC
LLKPYQVNAKLMARAAPDAIFMHCLPAHRGEEVTDEVMDGPQSVVFDEAENRLHAQKGIL
CCCCCCCCHHHHHHHCCHHHHHHHHCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
AWCLEKASA
HHHHHHHCC
>Mature Secondary Structure 
SGNGVRHFLDLTDLEAVDLRGVLELSKQLKAKRKAGTEEKPLAGKSLAMVFDKPSTRTR
CCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEECCCCCCHH
VSFDLAMRQLGGETIMLTGAEMQLGRGESIADTARVLSRFVDAIMIRILSHEDLLELAKF
HHHHHHHHHHCCCEEEEECCCEECCCCCCHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHH
ATVPVINGLTRVSHPCQVMADVLTFEEHKGSIEGRSVAWTGDANNVLASWVHAAAQFDFT
HHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCEEEEECCCHHHHHHHHHHHHHEEEE
INVATPKELSPRQALKEFVKRTQAKVRFMRDPEEAVEGVDCVITDTWVSMGDKEAERRHN
EEECCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHCCCEEEEEHHHHHCCCHHHHHHHC
LLKPYQVNAKLMARAAPDAIFMHCLPAHRGEEVTDEVMDGPQSVVFDEAENRLHAQKGIL
CCCCCCCCHHHHHHHCCHHHHHHHHCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
AWCLEKASA
HHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA