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The map label for this gene is sucC [H]

Identifier: 158425639

GI number: 158425639

Start: 4582611

End: 4583813

Strand: Reverse

Name: sucC [H]

Synonym: AZC_4015

Alternate gene names: 158425639

Gene position: 4583813-4582611 (Counterclockwise)

Preceding gene: 158425640

Following gene: 158425638

Centisome position: 85.36

GC content: 65.67

Gene sequence:

>1203_bases
ATGAATATCCATGAGTATCAGGCGAAGGCCCTGCTGAAGACCTACGGTGCGCCCGTGTCTCGCGGCGTGCCGGTCTTGGC
GGTGGGCGAGGCCGAGGCGGCCGCGCGTGAGCTGGGCGGCCCGCTCTGGGTCGTGAAGTCGCAGATCCATGCCGGCGGCC
GCGGCAAGGGCAAGTTCAAGGAGCCGGAAGCCGGCGACAAGGGCGGCGTGCGGCTGGCCCGGTCGGTGGAAGAGGTGAAG
ACCTTCGTCGAGCAGATGCTCGGCAACACGCTCGTGACCGTGCAGACCGGCCCGGCCGGCAAGCAGGTGAACCGCCTCTA
CATCGAGGAAGGTTCCGACATCGAGACCGAGTTCTACCTCTCGCTCCTCGTGGACCGCTCCACCTCGCGCGTCTCCTTCG
TGGTCTCCACCGAAGGCGGCATGGACATCGAGGAAGTGGCGCACTCCACCCCTGAGAAGATCGTCTCCTTCTCGGTGGAC
CCGGCCTCCGGCATCCAGGCTTTCCACGGCCGCAAGGTGGCCGATGCGCTCGGCCTCTCCGGCGACCTCGCCAAGCAGGC
GGGCAAGCTGACCGAGGTGCTCTACACCGCCTTCACCGACACCGACATGGCGATGCTGGAGATCAATCCGCTCATCGTCA
CCAAGGATGCCAAGCTGAAGGTGCTGGACGCCAAGGTGACGTTCGATTCCAACGCGCTGTTCCGCCATCCGGACCTGCTC
GCCCTGCGCGACGAGACGGAAGAGGACGCCAAGGAGATCGAAGCCTCCAAGTATGACCTCGCCTACATCGCGCTCGACGG
CACGATCGGCTGCATGGTGAACGGCGCGGGCCTCGCGATGGCGACCCTCGACATCATCAAGCTCTATGGCGAGAGCCCGG
CCAACTTCCTCGACGTGGGCGGCGGCGCCAGCGAGGAGAAGGTGACGGCGGCCTTCAAGATCATCACCTCGGACCCGAAC
GTGAAGGGCATCCTGGTGAACATCTTCGGCGGCATCATGAAGTGCGACGTGATCGCGCGCGGCGTGCTCGCCGCGGTGAC
CGCCGTCGGCCTCAAGGTTCCGCTGGTGGTGCGCCTCGAAGGCACCAACGTGGAGCAGGGCAAGCAGATCATCCGCGACA
GCGGCCTGAACGTGATCCCTGCCGATGACCTGGACGATGCGGCGCAGAAGATCGTCGCGGCCGTGAAGAAGGAAGCTGCG
TGA

Upstream 100 bases:

>100_bases
TTTTCGTGCCGGCGGGGGGACCCGGCGGCAATAGTCCAACCGGAGCGGATCGCCTTCGTCATGAGGGCGGGACGGTCCGA
AACTCTTGGGACGGAGCCCC

Downstream 100 bases:

>100_bases
TGTCCGTGCTTATTGACGCCAATACCAAGGTCATCACCCAGGGCTTCACGGGCAAGAACGGCACGTTCCACTCCGAGCAG
GCCATCGCCTACGGCACCAA

Product: succinyl-CoA synthetase subunit beta

Products: NA

Alternate protein names: Succinyl-CoA synthetase subunit beta; SCS-beta [H]

Number of amino acids: Translated: 400; Mature: 400

Protein sequence:

>400_residues
MNIHEYQAKALLKTYGAPVSRGVPVLAVGEAEAAARELGGPLWVVKSQIHAGGRGKGKFKEPEAGDKGGVRLARSVEEVK
TFVEQMLGNTLVTVQTGPAGKQVNRLYIEEGSDIETEFYLSLLVDRSTSRVSFVVSTEGGMDIEEVAHSTPEKIVSFSVD
PASGIQAFHGRKVADALGLSGDLAKQAGKLTEVLYTAFTDTDMAMLEINPLIVTKDAKLKVLDAKVTFDSNALFRHPDLL
ALRDETEEDAKEIEASKYDLAYIALDGTIGCMVNGAGLAMATLDIIKLYGESPANFLDVGGGASEEKVTAAFKIITSDPN
VKGILVNIFGGIMKCDVIARGVLAAVTAVGLKVPLVVRLEGTNVEQGKQIIRDSGLNVIPADDLDDAAQKIVAAVKKEAA

Sequences:

>Translated_400_residues
MNIHEYQAKALLKTYGAPVSRGVPVLAVGEAEAAARELGGPLWVVKSQIHAGGRGKGKFKEPEAGDKGGVRLARSVEEVK
TFVEQMLGNTLVTVQTGPAGKQVNRLYIEEGSDIETEFYLSLLVDRSTSRVSFVVSTEGGMDIEEVAHSTPEKIVSFSVD
PASGIQAFHGRKVADALGLSGDLAKQAGKLTEVLYTAFTDTDMAMLEINPLIVTKDAKLKVLDAKVTFDSNALFRHPDLL
ALRDETEEDAKEIEASKYDLAYIALDGTIGCMVNGAGLAMATLDIIKLYGESPANFLDVGGGASEEKVTAAFKIITSDPN
VKGILVNIFGGIMKCDVIARGVLAAVTAVGLKVPLVVRLEGTNVEQGKQIIRDSGLNVIPADDLDDAAQKIVAAVKKEAA
>Mature_400_residues
MNIHEYQAKALLKTYGAPVSRGVPVLAVGEAEAAARELGGPLWVVKSQIHAGGRGKGKFKEPEAGDKGGVRLARSVEEVK
TFVEQMLGNTLVTVQTGPAGKQVNRLYIEEGSDIETEFYLSLLVDRSTSRVSFVVSTEGGMDIEEVAHSTPEKIVSFSVD
PASGIQAFHGRKVADALGLSGDLAKQAGKLTEVLYTAFTDTDMAMLEINPLIVTKDAKLKVLDAKVTFDSNALFRHPDLL
ALRDETEEDAKEIEASKYDLAYIALDGTIGCMVNGAGLAMATLDIIKLYGESPANFLDVGGGASEEKVTAAFKIITSDPN
VKGILVNIFGGIMKCDVIARGVLAAVTAVGLKVPLVVRLEGTNVEQGKQIIRDSGLNVIPADDLDDAAQKIVAAVKKEAA

Specific function: Tricarboxylic acid cycle. [C]

COG id: COG0045

COG function: function code C; Succinyl-CoA synthetase, beta subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ATP-grasp domain [H]

Homologues:

Organism=Homo sapiens, GI11321583, Length=392, Percent_Identity=45.1530612244898, Blast_Score=345, Evalue=5e-95,
Organism=Homo sapiens, GI157779135, Length=386, Percent_Identity=46.8911917098446, Blast_Score=335, Evalue=3e-92,
Organism=Homo sapiens, GI294862256, Length=366, Percent_Identity=46.9945355191257, Blast_Score=316, Evalue=3e-86,
Organism=Escherichia coli, GI1786948, Length=396, Percent_Identity=52.5252525252525, Blast_Score=400, Evalue=1e-113,
Organism=Caenorhabditis elegans, GI17539378, Length=397, Percent_Identity=44.8362720403023, Blast_Score=338, Evalue=2e-93,
Organism=Caenorhabditis elegans, GI17567829, Length=394, Percent_Identity=45.1776649746193, Blast_Score=332, Evalue=2e-91,
Organism=Saccharomyces cerevisiae, GI6321683, Length=395, Percent_Identity=44.3037974683544, Blast_Score=339, Evalue=5e-94,
Organism=Drosophila melanogaster, GI21356231, Length=397, Percent_Identity=47.8589420654912, Blast_Score=351, Evalue=5e-97,
Organism=Drosophila melanogaster, GI161078106, Length=388, Percent_Identity=47.4226804123711, Blast_Score=342, Evalue=2e-94,
Organism=Drosophila melanogaster, GI24645208, Length=388, Percent_Identity=47.4226804123711, Blast_Score=342, Evalue=2e-94,
Organism=Drosophila melanogaster, GI281361397, Length=391, Percent_Identity=47.5703324808184, Blast_Score=340, Evalue=1e-93,
Organism=Drosophila melanogaster, GI281361395, Length=391, Percent_Identity=47.5703324808184, Blast_Score=340, Evalue=1e-93,

Paralogues:

None

Copy number: 340 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2361 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 3,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011761
- InterPro:   IPR013650
- InterPro:   IPR013815
- InterPro:   IPR013816
- InterPro:   IPR005811
- InterPro:   IPR017866
- InterPro:   IPR005809
- InterPro:   IPR016102 [H]

Pfam domain/function: PF08442 ATP-grasp_2; PF00549 Ligase_CoA [H]

EC number: =6.2.1.5 [H]

Molecular weight: Translated: 42398; Mature: 42398

Theoretical pI: Translated: 4.79; Mature: 4.79

Prosite motif: PS50975 ATP_GRASP ; PS01217 SUCCINYL_COA_LIG_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIHEYQAKALLKTYGAPVSRGVPVLAVGEAEAAARELGGPLWVVKSQIHAGGRGKGKFK
CCCHHHHHHHHHHHHCCCHHCCCCEEEECCHHHHHHHHCCCEEEEEHHHCCCCCCCCCCC
EPEAGDKGGVRLARSVEEVKTFVEQMLGNTLVTVQTGPAGKQVNRLYIEEGSDIETEFYL
CCCCCCCCCHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCCCEEEEEEECCCCCCHHEEE
SLLVDRSTSRVSFVVSTEGGMDIEEVAHSTPEKIVSFSVDPASGIQAFHGRKVADALGLS
EEEEECCCCEEEEEEECCCCCCHHHHHCCCCHHHEEEECCCHHHHHHHCCCHHHHHHCCC
GDLAKQAGKLTEVLYTAFTDTDMAMLEINPLIVTKDAKLKVLDAKVTFDSNALFRHPDLL
HHHHHHHHHHHHHHHHHHCCCCEEEEEECCEEEECCCEEEEEEEEEEECCCCEEECCCEE
ALRDETEEDAKEIEASKYDLAYIALDGTIGCMVNGAGLAMATLDIIKLYGESPANFLDVG
EECCCCHHHHHHHCCCCCEEEEEEECCCEEEEEECCCHHHHHHHHHHHHCCCCCCEEECC
GGASEEKVTAAFKIITSDPNVKGILVNIFGGIMKCDVIARGVLAAVTAVGLKVPLVVRLE
CCCCCCCEEEEEEEEECCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEE
GTNVEQGKQIIRDSGLNVIPADDLDDAAQKIVAAVKKEAA
CCCHHHHHHHHHHCCCEEECCCCHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNIHEYQAKALLKTYGAPVSRGVPVLAVGEAEAAARELGGPLWVVKSQIHAGGRGKGKFK
CCCHHHHHHHHHHHHCCCHHCCCCEEEECCHHHHHHHHCCCEEEEEHHHCCCCCCCCCCC
EPEAGDKGGVRLARSVEEVKTFVEQMLGNTLVTVQTGPAGKQVNRLYIEEGSDIETEFYL
CCCCCCCCCHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCCCEEEEEEECCCCCCHHEEE
SLLVDRSTSRVSFVVSTEGGMDIEEVAHSTPEKIVSFSVDPASGIQAFHGRKVADALGLS
EEEEECCCCEEEEEEECCCCCCHHHHHCCCCHHHEEEECCCHHHHHHHCCCHHHHHHCCC
GDLAKQAGKLTEVLYTAFTDTDMAMLEINPLIVTKDAKLKVLDAKVTFDSNALFRHPDLL
HHHHHHHHHHHHHHHHHHCCCCEEEEEECCEEEECCCEEEEEEEEEEECCCCEEECCCEE
ALRDETEEDAKEIEASKYDLAYIALDGTIGCMVNGAGLAMATLDIIKLYGESPANFLDVG
EECCCCHHHHHHHCCCCCEEEEEEECCCEEEEEECCCHHHHHHHHHHHHCCCCCCEEECC
GGASEEKVTAAFKIITSDPNVKGILVNIFGGIMKCDVIARGVLAAVTAVGLKVPLVVRLE
CCCCCCCEEEEEEEEECCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEE
GTNVEQGKQIIRDSGLNVIPADDLDDAAQKIVAAVKKEAA
CCCHHHHHHHHHHCCCEEECCCCHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA