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The map label for this gene is allB [H]

Identifier: 158425521

GI number: 158425521

Start: 4449014

End: 4450450

Strand: Reverse

Name: allB [H]

Synonym: AZC_3897

Alternate gene names: 158425521

Gene position: 4450450-4449014 (Counterclockwise)

Preceding gene: 158425522

Following gene: 158425520

Centisome position: 82.88

GC content: 67.99

Gene sequence:

>1437_bases
ATGAGCGAACCTGCGGATCTGGTCATCCACGGCGGTCGGATCGTCTCGCCGGAGACGGTCCTGGAGGCCTCCATTGCCGT
GCGCGGCGGCACCATCGTCGCGGTGGGCGCGGCGGACGCCATGCCGGAGGCGAAGGAGACCTTCGATGCTTCCGGCCTGC
ACATCCTGCCCGGTGCCATCGACGTGCACGTGCACTTCCGGGACCCCGGCTACACCCACAAGGAAGATTTCGAGAGCGGC
ACGGCCGCCGCGGCCTTCGGCGGCGTGACCACCGTCTTCGACATGCCAAACACCATCCCAACGGTGGCCGATGGCGAGAC
CCTGAGGGCCAAGCACGCCATTGCGGCGTCAAAGGCGCATGTGGACTACGGCCTCTATGCGGTGCTGGGCGAGGATACGA
TCGGGAAGGTGTCGGAGCTGATCGAGGCCGGAATCATCGGCTTCAAATGCTACATGGGTAACACCTTCGGCCGCATTCCC
TCGCCCTCCACCGGGGCGATGCTGGAGGCCTTCGAGGTGGTGGCGCCCACGGGCAAGCGCATCTCCCTCCATGCCGAGAC
CAATTCGGTGATGGAGCGCCGCCAGCAGCGCCTCACCGACAGCGGGCGTGCCGATCCGCTTGCCCATCTGGCCTCCCGTC
CCGCGGTGGTGGCGGTGGAGGCGGTGGCCCGCGCGGCGATCCTCGCCGAATGGACGGGCGCGCGCATCCACATCCTCCAC
ATCTCCTCCGCCGCCGAACTGCGGCCGCTGCGCGATGCCAAGGCGCGCGGTGTGGACATCACGGGCGAGACCTGCCCGCA
TTACATGATGTTGGGCGAAGCGGATTATGCCCGCTGCCGGGGCGTGATCCGGGTCAATCCGCCAGTGCGCGAGAGCGCCA
ATGACGCCCCCCTGTGGGCGGCCCTCATCGACGGCACCATCGACATGATCGCCACCGATCATGCGCCCCACACGCCGGAG
GAGAAGACCCGCGCCGACATCTGGGCCGTGGACTGCGGCTTCCCGGGCGTCGAGACCCAGATGCCGCTCATGCTGACCGA
AGTAGCGGCAGGCCGCTATTCCATCTGCGATTATGTGCGTTGGAGCGCGGTCAATCCGGCCAAGGTGTGGGGTCTCTATC
CCCGCAAGGGCGTGATTCAGCCCCGCGCCGATGCCGATTTCGCCTTCGTCGATCTCGACCACGCCTGGACGCTGCGCGAC
GCCGATCTTCAGTCGCGCTCGAAGATCTCTCCCTGGGACGGCAGGCCCGTGGTCGGGCTGCCACGCCACACCATGGTGCG
CGGCCGCTTCGTGATGAAGAACCGCGCGCTGGTGGCGGACACCAAGGGCCACGGCCGTTCCGTCCATGTCATCCAGCAGA
TGCCCGAGCCGCGCCCCCTCCACACGGACGAGACACTGGCCGCCGTCATCGCCGCCCGTCCGGAGGCGGCGGCATGA

Upstream 100 bases:

>100_bases
GCCAATGCCTGCCTGTTCCTCGCCAGCGACGTTTCCCGCCAGCTCACCGGCATCGACATGCCGGTCGATGGCGGCTGGGC
CATGCTCTGAGGAGGGCGAC

Downstream 100 bases:

>100_bases
ACGAGGATGCGCCCACCTTCGTCCAGCTTGAGGACGTGCGGCTCACGTATGGCCGCGGCGAGCGCATGGTGGAGGCCCTC
GGCACCACCAATCTCAAGAT

Product: allantoinase

Products: NA

Alternate protein names: Allantoin-utilizing enzyme [H]

Number of amino acids: Translated: 478; Mature: 477

Protein sequence:

>478_residues
MSEPADLVIHGGRIVSPETVLEASIAVRGGTIVAVGAADAMPEAKETFDASGLHILPGAIDVHVHFRDPGYTHKEDFESG
TAAAAFGGVTTVFDMPNTIPTVADGETLRAKHAIAASKAHVDYGLYAVLGEDTIGKVSELIEAGIIGFKCYMGNTFGRIP
SPSTGAMLEAFEVVAPTGKRISLHAETNSVMERRQQRLTDSGRADPLAHLASRPAVVAVEAVARAAILAEWTGARIHILH
ISSAAELRPLRDAKARGVDITGETCPHYMMLGEADYARCRGVIRVNPPVRESANDAPLWAALIDGTIDMIATDHAPHTPE
EKTRADIWAVDCGFPGVETQMPLMLTEVAAGRYSICDYVRWSAVNPAKVWGLYPRKGVIQPRADADFAFVDLDHAWTLRD
ADLQSRSKISPWDGRPVVGLPRHTMVRGRFVMKNRALVADTKGHGRSVHVIQQMPEPRPLHTDETLAAVIAARPEAAA

Sequences:

>Translated_478_residues
MSEPADLVIHGGRIVSPETVLEASIAVRGGTIVAVGAADAMPEAKETFDASGLHILPGAIDVHVHFRDPGYTHKEDFESG
TAAAAFGGVTTVFDMPNTIPTVADGETLRAKHAIAASKAHVDYGLYAVLGEDTIGKVSELIEAGIIGFKCYMGNTFGRIP
SPSTGAMLEAFEVVAPTGKRISLHAETNSVMERRQQRLTDSGRADPLAHLASRPAVVAVEAVARAAILAEWTGARIHILH
ISSAAELRPLRDAKARGVDITGETCPHYMMLGEADYARCRGVIRVNPPVRESANDAPLWAALIDGTIDMIATDHAPHTPE
EKTRADIWAVDCGFPGVETQMPLMLTEVAAGRYSICDYVRWSAVNPAKVWGLYPRKGVIQPRADADFAFVDLDHAWTLRD
ADLQSRSKISPWDGRPVVGLPRHTMVRGRFVMKNRALVADTKGHGRSVHVIQQMPEPRPLHTDETLAAVIAARPEAAA
>Mature_477_residues
SEPADLVIHGGRIVSPETVLEASIAVRGGTIVAVGAADAMPEAKETFDASGLHILPGAIDVHVHFRDPGYTHKEDFESGT
AAAAFGGVTTVFDMPNTIPTVADGETLRAKHAIAASKAHVDYGLYAVLGEDTIGKVSELIEAGIIGFKCYMGNTFGRIPS
PSTGAMLEAFEVVAPTGKRISLHAETNSVMERRQQRLTDSGRADPLAHLASRPAVVAVEAVARAAILAEWTGARIHILHI
SSAAELRPLRDAKARGVDITGETCPHYMMLGEADYARCRGVIRVNPPVRESANDAPLWAALIDGTIDMIATDHAPHTPEE
KTRADIWAVDCGFPGVETQMPLMLTEVAAGRYSICDYVRWSAVNPAKVWGLYPRKGVIQPRADADFAFVDLDHAWTLRDA
DLQSRSKISPWDGRPVVGLPRHTMVRGRFVMKNRALVADTKGHGRSVHVIQQMPEPRPLHTDETLAAVIAARPEAAA

Specific function: Catalyzes the conversion of allantoin (5- ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring [H]

COG id: COG0044

COG function: function code F; Dihydroorotase and related cyclic amidohydrolases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DHOase family. Allantoinase subfamily [H]

Homologues:

Organism=Homo sapiens, GI18105007, Length=417, Percent_Identity=31.89448441247, Blast_Score=184, Evalue=2e-46,
Organism=Homo sapiens, GI4503379, Length=458, Percent_Identity=26.8558951965066, Blast_Score=153, Evalue=3e-37,
Organism=Homo sapiens, GI4503051, Length=458, Percent_Identity=26.4192139737991, Blast_Score=147, Evalue=2e-35,
Organism=Homo sapiens, GI62422571, Length=458, Percent_Identity=26.4192139737991, Blast_Score=147, Evalue=2e-35,
Organism=Homo sapiens, GI190194363, Length=462, Percent_Identity=27.9220779220779, Blast_Score=147, Evalue=2e-35,
Organism=Homo sapiens, GI4503377, Length=460, Percent_Identity=27.3913043478261, Blast_Score=147, Evalue=3e-35,
Organism=Homo sapiens, GI19923821, Length=446, Percent_Identity=26.457399103139, Blast_Score=135, Evalue=1e-31,
Organism=Homo sapiens, GI4503375, Length=468, Percent_Identity=25.2136752136752, Blast_Score=123, Evalue=4e-28,
Organism=Escherichia coli, GI1786722, Length=433, Percent_Identity=32.1016166281755, Blast_Score=243, Evalue=1e-65,
Organism=Escherichia coli, GI87082175, Length=455, Percent_Identity=28.5714285714286, Blast_Score=194, Evalue=1e-50,
Organism=Caenorhabditis elegans, GI193204318, Length=418, Percent_Identity=31.1004784688995, Blast_Score=187, Evalue=7e-48,
Organism=Caenorhabditis elegans, GI71989490, Length=477, Percent_Identity=26.4150943396226, Blast_Score=130, Evalue=1e-30,
Organism=Caenorhabditis elegans, GI17539558, Length=464, Percent_Identity=26.2931034482759, Blast_Score=127, Evalue=1e-29,
Organism=Caenorhabditis elegans, GI86575075, Length=436, Percent_Identity=24.7706422018349, Blast_Score=101, Evalue=8e-22,
Organism=Saccharomyces cerevisiae, GI6322218, Length=453, Percent_Identity=30.242825607064, Blast_Score=191, Evalue=3e-49,
Organism=Drosophila melanogaster, GI24642586, Length=409, Percent_Identity=33.7408312958435, Blast_Score=199, Evalue=4e-51,
Organism=Drosophila melanogaster, GI221377917, Length=500, Percent_Identity=27.8, Blast_Score=149, Evalue=3e-36,
Organism=Drosophila melanogaster, GI17137462, Length=489, Percent_Identity=28.0163599182004, Blast_Score=149, Evalue=6e-36,
Organism=Drosophila melanogaster, GI18859883, Length=454, Percent_Identity=28.8546255506608, Blast_Score=140, Evalue=3e-33,
Organism=Drosophila melanogaster, GI24644287, Length=273, Percent_Identity=31.1355311355311, Blast_Score=102, Evalue=6e-22,
Organism=Drosophila melanogaster, GI24644289, Length=235, Percent_Identity=31.4893617021277, Blast_Score=95, Evalue=1e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017593
- InterPro:   IPR006680
- InterPro:   IPR004722
- InterPro:   IPR002195
- InterPro:   IPR011059 [H]

Pfam domain/function: PF01979 Amidohydro_1 [H]

EC number: =3.5.2.5 [H]

Molecular weight: Translated: 51427; Mature: 51296

Theoretical pI: Translated: 6.47; Mature: 6.47

Prosite motif: PS00482 DIHYDROOROTASE_1 ; PS00483 DIHYDROOROTASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEPADLVIHGGRIVSPETVLEASIAVRGGTIVAVGAADAMPEAKETFDASGLHILPGAI
CCCCCCEEEECCEEECHHHHHEEEEEEECCEEEEEECCCCCCCHHHHCCCCCCEEECCEE
DVHVHFRDPGYTHKEDFESGTAAAAFGGVTTVFDMPNTIPTVADGETLRAKHAIAASKAH
EEEEEECCCCCCCHHHCCCCCCHHHHCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHHCC
VDYGLYAVLGEDTIGKVSELIEAGIIGFKCYMGNTFGRIPSPSTGAMLEAFEVVAPTGKR
CCCCEEEEECCCHHHHHHHHHHHCCEEEEEEECCCCCCCCCCCCCHHHHHHHHCCCCCCE
ISLHAETNSVMERRQQRLTDSGRADPLAHLASRPAVVAVEAVARAAILAEWTGARIHILH
EEEEECHHHHHHHHHHHHCCCCCCCHHHHHHCCCCEEEHHHHHHHHHHEECCCCEEEEEE
ISSAAELRPLRDAKARGVDITGETCPHYMMLGEADYARCRGVIRVNPPVRESANDAPLWA
ECCCHHCCCCHHHHHCCEECCCCCCCCEEEECCCCHHHCCCEEEECCCCCCCCCCCCEEE
ALIDGTIDMIATDHAPHTPEEKTRADIWAVDCGFPGVETQMPLMLTEVAAGRYSICDYVR
EECCCCEEEEEECCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCEEHHCCCCHHHHHHHH
WSAVNPAKVWGLYPRKGVIQPRADADFAFVDLDHAWTLRDADLQSRSKISPWDGRPVVGL
HCCCCHHHHEECCCCCCCCCCCCCCCEEEEECCCEEEEECCCCCCCCCCCCCCCCCEECC
PRHTMVRGRFVMKNRALVADTKGHGRSVHVIQQMPEPRPLHTDETLAAVIAARPEAAA
CCCHHEECEEEEECCEEEEECCCCCCEEHHHHHCCCCCCCCCCHHHHHHHHCCCCCCC
>Mature Secondary Structure 
SEPADLVIHGGRIVSPETVLEASIAVRGGTIVAVGAADAMPEAKETFDASGLHILPGAI
CCCCCEEEECCEEECHHHHHEEEEEEECCEEEEEECCCCCCCHHHHCCCCCCEEECCEE
DVHVHFRDPGYTHKEDFESGTAAAAFGGVTTVFDMPNTIPTVADGETLRAKHAIAASKAH
EEEEEECCCCCCCHHHCCCCCCHHHHCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHHCC
VDYGLYAVLGEDTIGKVSELIEAGIIGFKCYMGNTFGRIPSPSTGAMLEAFEVVAPTGKR
CCCCEEEEECCCHHHHHHHHHHHCCEEEEEEECCCCCCCCCCCCCHHHHHHHHCCCCCCE
ISLHAETNSVMERRQQRLTDSGRADPLAHLASRPAVVAVEAVARAAILAEWTGARIHILH
EEEEECHHHHHHHHHHHHCCCCCCCHHHHHHCCCCEEEHHHHHHHHHHEECCCCEEEEEE
ISSAAELRPLRDAKARGVDITGETCPHYMMLGEADYARCRGVIRVNPPVRESANDAPLWA
ECCCHHCCCCHHHHHCCEECCCCCCCCEEEECCCCHHHCCCEEEECCCCCCCCCCCCEEE
ALIDGTIDMIATDHAPHTPEEKTRADIWAVDCGFPGVETQMPLMLTEVAAGRYSICDYVR
EECCCCEEEEEECCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCEEHHCCCCHHHHHHHH
WSAVNPAKVWGLYPRKGVIQPRADADFAFVDLDHAWTLRDADLQSRSKISPWDGRPVVGL
HCCCCHHHHEECCCCCCCCCCCCCCCEEEEECCCEEEEECCCCCCCCCCCCCCCCCEECC
PRHTMVRGRFVMKNRALVADTKGHGRSVHVIQQMPEPRPLHTDETLAAVIAARPEAAA
CCCHHEECEEEEECCEEEEECCCCCCEEHHHHHCCCCCCCCCCHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA