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The map label for this gene is yafV [C]

Identifier: 158425507

GI number: 158425507

Start: 4434100

End: 4435854

Strand: Reverse

Name: yafV [C]

Synonym: AZC_3883

Alternate gene names: 158425507

Gene position: 4435854-4434100 (Counterclockwise)

Preceding gene: 158425508

Following gene: 158425506

Centisome position: 82.61

GC content: 67.35

Gene sequence:

>1755_bases
ATGTCCGAGACCATCACCGTTGCCACCGTCCAGTTCGAGCCGACCCTGTTCGAGAAGGAGCGCAACATCACGCGCCTTCT
CGCCTTGTGCGAGCAGGCCGCGCGCGCGGGCGCAAAGCTCATCGTGACGCCCGAAATGGGTACCACCGGCTATTGCTGGT
TCGACCGTGCCGAGGTGGCCGGGCAGGTGGAGAGCGTGCCCGGACCCACCACCGAGCGCTTCGCCGCTCTGGCCCGCGAG
CACGGCTGCTGGATCGTCATCGGCATGCCGGAGGTCGATGCGGACGACATCTACTTCAACAGTGCCGTCCTTATCGGTCC
TGATGGCGTGGTGGGCACCCACCGCAAGAGCCATCCCTATATCTCCGAGCCCAAGTGGTCCGCCGCCGGCGATCTCGGCC
ATCAGGTGTTCGAGACGCCCATCGGCCGCATCGGCCTGCTGATCTGCATGGACATCCATTTCATCGAGACCGCGCGCCTC
ATGGCGGTGCAGGGCGCCGACGTCATCTGCCACATCTCCAACTGGCTGGCGGAGCGCACCCCCGCGCCTTACTGGATCAG
CCGCGCGTTCGAGAATGGCTGCTATGTGATCGAGGCCAATCGCTGGGGCCTGGAGCGCACGGTGCAATTCTCCGGCGGCA
GCTGCGTCATCGAGCCGGACGGCAGCATCGTGGCCGTGATCGACAGCGGTGATGGCTTTGCCCTGGCGCAGATGGACCTT
GCCAAGGCCCGCGCCCGAACCGTTTTGGGCGAGCCGGTCTTCACCCAGCGCCGGCCGGAACTCTATCGCGAGCTGCTCTC
GGACACCTTCAGCTGGAACCCGCGCGATTTCTTCACGCTCTATGGCCACCGCCCGCTGCCGCCGGGGCGCGCGTCGCGGG
TGGCCGTGGCGCAGTTCGCCCCTGGCGAGGGCATTGCGGACAATCTCTCCCGCATCTGCGCCTTCGCGGTGCAGGCGCGC
ACGGAGGAGGGGGCCGATCTCGTCGTCTTCCCGGAACTGGCGCTGAGCGGGCTGTCGGATCCGGCCGTCAGGGCGCTCTC
ATCCGACGACCCCGCTTTCATGCGCCTGCTGAACCTCTCTGCCCGGCTCGGTCTCCATATGGTGGTCGGCTTCGCGGAAC
GGGCGGCCGATGGTCTCTACAACAGCGCCGCACTCCTCGGGCCGGAGGGGCTTGTTGCCATCCATCGCAAGCTGCATCTG
AATGCCGCCGATCGCCCGTGGGCGACGCCGGGCGCGGACTGGACGGTGGCGGACACAAGCCTTGGCCGCATCGGCCTCCT
CATCGGCCACGATGCCACCTTCTGCGAGAGCGGGCGTATCCTGGCCCTGAGGGGCTGTGATCTCATCGCCTGCCCGGCCG
CCATCGCCGGGCGCTTCAGCTATGGGCACGGGGGCTCCCGCGTGGCCCAGAACTGGCCCATCCCGACGGGTGCCGATCCG
CACCATTGGCATCATTTCCGGGTGCGCGCGGGCGAGAACAACGTCTTCCTCGCGTTCGCCAACGTCCATGCGCCGGAGGC
GGGCTTCATGGGGCTGAGCGGCGTGTTCGGGCCGGATACCTTCGCCTTCCCTCGCTCAGAGGCACTGTTGCCAGAAGGCG
AGGGGCTGGCGGTGGCAATCATGGACACGAGCAATCTCGATACGCCCTATCCGACCAATGTGGTGCGCCGCAAAGACCTG
GTGGCGATGCGCTTGCCCCATCACTATCGGGACCTCGTGCGCGGCGCCAAGCGGCGCCACCCATCGGCCAGCTAA

Upstream 100 bases:

>100_bases
ACCTTCCTCGTCTGATCCGGCGCCTGTCGCACGCCCAAAACACGGCCGGCGGCGGGCGCGTCCCGCCGCTCATTCCAGTT
GATCCCTGAGGCGGGCCATC

Downstream 100 bases:

>100_bases
GGCGCAAGGATAATGCAGCGGCGGGAGGCTTCGGTCTCTCGTCTTGCTCTGGCGCGCGCGAAGGCGCGCGTTCGCTCGAA
CCCATCACGCGCCAAAACAC

Product: nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase

Products: NA

Alternate protein names: ORF2 [H]

Number of amino acids: Translated: 584; Mature: 583

Protein sequence:

>584_residues
MSETITVATVQFEPTLFEKERNITRLLALCEQAARAGAKLIVTPEMGTTGYCWFDRAEVAGQVESVPGPTTERFAALARE
HGCWIVIGMPEVDADDIYFNSAVLIGPDGVVGTHRKSHPYISEPKWSAAGDLGHQVFETPIGRIGLLICMDIHFIETARL
MAVQGADVICHISNWLAERTPAPYWISRAFENGCYVIEANRWGLERTVQFSGGSCVIEPDGSIVAVIDSGDGFALAQMDL
AKARARTVLGEPVFTQRRPELYRELLSDTFSWNPRDFFTLYGHRPLPPGRASRVAVAQFAPGEGIADNLSRICAFAVQAR
TEEGADLVVFPELALSGLSDPAVRALSSDDPAFMRLLNLSARLGLHMVVGFAERAADGLYNSAALLGPEGLVAIHRKLHL
NAADRPWATPGADWTVADTSLGRIGLLIGHDATFCESGRILALRGCDLIACPAAIAGRFSYGHGGSRVAQNWPIPTGADP
HHWHHFRVRAGENNVFLAFANVHAPEAGFMGLSGVFGPDTFAFPRSEALLPEGEGLAVAIMDTSNLDTPYPTNVVRRKDL
VAMRLPHHYRDLVRGAKRRHPSAS

Sequences:

>Translated_584_residues
MSETITVATVQFEPTLFEKERNITRLLALCEQAARAGAKLIVTPEMGTTGYCWFDRAEVAGQVESVPGPTTERFAALARE
HGCWIVIGMPEVDADDIYFNSAVLIGPDGVVGTHRKSHPYISEPKWSAAGDLGHQVFETPIGRIGLLICMDIHFIETARL
MAVQGADVICHISNWLAERTPAPYWISRAFENGCYVIEANRWGLERTVQFSGGSCVIEPDGSIVAVIDSGDGFALAQMDL
AKARARTVLGEPVFTQRRPELYRELLSDTFSWNPRDFFTLYGHRPLPPGRASRVAVAQFAPGEGIADNLSRICAFAVQAR
TEEGADLVVFPELALSGLSDPAVRALSSDDPAFMRLLNLSARLGLHMVVGFAERAADGLYNSAALLGPEGLVAIHRKLHL
NAADRPWATPGADWTVADTSLGRIGLLIGHDATFCESGRILALRGCDLIACPAAIAGRFSYGHGGSRVAQNWPIPTGADP
HHWHHFRVRAGENNVFLAFANVHAPEAGFMGLSGVFGPDTFAFPRSEALLPEGEGLAVAIMDTSNLDTPYPTNVVRRKDL
VAMRLPHHYRDLVRGAKRRHPSAS
>Mature_583_residues
SETITVATVQFEPTLFEKERNITRLLALCEQAARAGAKLIVTPEMGTTGYCWFDRAEVAGQVESVPGPTTERFAALAREH
GCWIVIGMPEVDADDIYFNSAVLIGPDGVVGTHRKSHPYISEPKWSAAGDLGHQVFETPIGRIGLLICMDIHFIETARLM
AVQGADVICHISNWLAERTPAPYWISRAFENGCYVIEANRWGLERTVQFSGGSCVIEPDGSIVAVIDSGDGFALAQMDLA
KARARTVLGEPVFTQRRPELYRELLSDTFSWNPRDFFTLYGHRPLPPGRASRVAVAQFAPGEGIADNLSRICAFAVQART
EEGADLVVFPELALSGLSDPAVRALSSDDPAFMRLLNLSARLGLHMVVGFAERAADGLYNSAALLGPEGLVAIHRKLHLN
AADRPWATPGADWTVADTSLGRIGLLIGHDATFCESGRILALRGCDLIACPAAIAGRFSYGHGGSRVAQNWPIPTGADPH
HWHHFRVRAGENNVFLAFANVHAPEAGFMGLSGVFGPDTFAFPRSEALLPEGEGLAVAIMDTSNLDTPYPTNVVRRKDLV
AMRLPHHYRDLVRGAKRRHPSAS

Specific function: Unknown

COG id: COG0388

COG function: function code R; Predicted amidohydrolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 CN hydrolase domain [H]

Homologues:

Organism=Homo sapiens, GI5031947, Length=283, Percent_Identity=32.5088339222615, Blast_Score=105, Evalue=2e-22,
Organism=Homo sapiens, GI297632348, Length=283, Percent_Identity=32.5088339222615, Blast_Score=104, Evalue=2e-22,
Organism=Homo sapiens, GI297632350, Length=283, Percent_Identity=32.5088339222615, Blast_Score=104, Evalue=2e-22,
Organism=Homo sapiens, GI9910460, Length=260, Percent_Identity=30.3846153846154, Blast_Score=102, Evalue=1e-21,
Organism=Homo sapiens, GI7706509, Length=248, Percent_Identity=29.8387096774194, Blast_Score=78, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17556280, Length=261, Percent_Identity=27.2030651340996, Blast_Score=85, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17533173, Length=251, Percent_Identity=31.8725099601594, Blast_Score=82, Evalue=6e-16,
Organism=Saccharomyces cerevisiae, GI6323383, Length=289, Percent_Identity=27.3356401384083, Blast_Score=77, Evalue=6e-15,
Organism=Drosophila melanogaster, GI21358471, Length=282, Percent_Identity=28.0141843971631, Blast_Score=82, Evalue=1e-15,
Organism=Drosophila melanogaster, GI17933642, Length=276, Percent_Identity=25, Blast_Score=76, Evalue=8e-14,
Organism=Drosophila melanogaster, GI21355835, Length=217, Percent_Identity=28.5714285714286, Blast_Score=70, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003010
- InterPro:   IPR001110 [H]

Pfam domain/function: PF00795 CN_hydrolase [H]

EC number: 3.5.-.- [C]

Molecular weight: Translated: 63444; Mature: 63313

Theoretical pI: Translated: 6.34; Mature: 6.34

Prosite motif: PS00485 A_DEAMINASE ; PS50263 CN_HYDROLASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSETITVATVQFEPTLFEKERNITRLLALCEQAARAGAKLIVTPEMGTTGYCWFDRAEVA
CCCEEEEEEEEECCCHHHHHCHHHHHHHHHHHHHHCCCEEEEECCCCCCEEEEECCHHHC
GQVESVPGPTTERFAALAREHGCWIVIGMPEVDADDIYFNSAVLIGPDGVVGTHRKSHPY
CHHHCCCCCCHHHHHHHHHCCCCEEEEECCCCCCCCEEECCEEEECCCCCCCCCCCCCCC
ISEPKWSAAGDLGHQVFETPIGRIGLLICMDIHFIETARLMAVQGADVICHISNWLAERT
CCCCCCCCCCHHHHHHHHCCHHHHEEEEEEEHHHHHHEEEEEECCCCEEEEEHHHHHHCC
PAPYWISRAFENGCYVIEANRWGLERTVQFSGGSCVIEPDGSIVAVIDSGDGFALAQMDL
CCCHHHHHHHCCCEEEEECCCCCCEEEEEECCCEEEECCCCCEEEEEECCCCEEEEHHHH
AKARARTVLGEPVFTQRRPELYRELLSDTFSWNPRDFFTLYGHRPLPPGRASRVAVAQFA
HHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCEEEEEEEC
PGEGIADNLSRICAFAVQARTEEGADLVVFPELALSGLSDPAVRALSSDDPAFMRLLNLS
CCCCHHHHHHHHHHHHHHHCCCCCCCEEEEHHHHHCCCCCHHHHHCCCCCHHHHHHHHHH
ARLGLHMVVGFAERAADGLYNSAALLGPEGLVAIHRKLHLNAADRPWATPGADWTVADTS
HHCCHHHHHHHHHHHHCCCCCCEEEECCCCCEEEEHEEECCCCCCCCCCCCCCEEEECCC
LGRIGLLIGHDATFCESGRILALRGCDLIACPAAIAGRFSYGHGGSRVAQNWPIPTGADP
CCEEEEEEECCCCEECCCCEEEEECCCEEECCHHHHCCCCCCCCCCCCCCCCCCCCCCCC
HHWHHFRVRAGENNVFLAFANVHAPEAGFMGLSGVFGPDTFAFPRSEALLPEGEGLAVAI
CCEEEEEEEECCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEE
MDTSNLDTPYPTNVVRRKDLVAMRLPHHYRDLVRGAKRRHPSAS
EECCCCCCCCCCHHHHHCCCEEECCCHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
SETITVATVQFEPTLFEKERNITRLLALCEQAARAGAKLIVTPEMGTTGYCWFDRAEVA
CCEEEEEEEEECCCHHHHHCHHHHHHHHHHHHHHCCCEEEEECCCCCCEEEEECCHHHC
GQVESVPGPTTERFAALAREHGCWIVIGMPEVDADDIYFNSAVLIGPDGVVGTHRKSHPY
CHHHCCCCCCHHHHHHHHHCCCCEEEEECCCCCCCCEEECCEEEECCCCCCCCCCCCCCC
ISEPKWSAAGDLGHQVFETPIGRIGLLICMDIHFIETARLMAVQGADVICHISNWLAERT
CCCCCCCCCCHHHHHHHHCCHHHHEEEEEEEHHHHHHEEEEEECCCCEEEEEHHHHHHCC
PAPYWISRAFENGCYVIEANRWGLERTVQFSGGSCVIEPDGSIVAVIDSGDGFALAQMDL
CCCHHHHHHHCCCEEEEECCCCCCEEEEEECCCEEEECCCCCEEEEEECCCCEEEEHHHH
AKARARTVLGEPVFTQRRPELYRELLSDTFSWNPRDFFTLYGHRPLPPGRASRVAVAQFA
HHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCEEEEEEEC
PGEGIADNLSRICAFAVQARTEEGADLVVFPELALSGLSDPAVRALSSDDPAFMRLLNLS
CCCCHHHHHHHHHHHHHHHCCCCCCCEEEEHHHHHCCCCCHHHHHCCCCCHHHHHHHHHH
ARLGLHMVVGFAERAADGLYNSAALLGPEGLVAIHRKLHLNAADRPWATPGADWTVADTS
HHCCHHHHHHHHHHHHCCCCCCEEEECCCCCEEEEHEEECCCCCCCCCCCCCCEEEECCC
LGRIGLLIGHDATFCESGRILALRGCDLIACPAAIAGRFSYGHGGSRVAQNWPIPTGADP
CCEEEEEEECCCCEECCCCEEEEECCCEEECCHHHHCCCCCCCCCCCCCCCCCCCCCCCC
HHWHHFRVRAGENNVFLAFANVHAPEAGFMGLSGVFGPDTFAFPRSEALLPEGEGLAVAI
CCEEEEEEEECCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEE
MDTSNLDTPYPTNVVRRKDLVAMRLPHHYRDLVRGAKRRHPSAS
EECCCCCCCCCCHHHHHCCCEEECCCHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8526497 [H]