Click here to switch to the map view.

The map label for this gene is sdhB [H]

Identifier: 158425370

GI number: 158425370

Start: 4298478

End: 4299263

Strand: Direct

Name: sdhB [H]

Synonym: AZC_3746

Alternate gene names: 158425370

Gene position: 4298478-4299263 (Clockwise)

Preceding gene: 158425369

Following gene: 158425372

Centisome position: 80.05

GC content: 63.87

Gene sequence:

>786_bases
ATGGCTGAGTTCACCCTCCCGAAGAATTCGCAGATCACAAAGGGCAAGACCTGGCCGAAGCCCCAGGCTGCCAAGAAGGT
CACCGAGTTCCGCGTCTATCGCTGGAACCCCGATGACGGGAAGAACCCGTCCATCGACACCTATTACGTGGACCGCGAAG
CCTGCGGCCCCATGGTTCTCGATGGTCTCATCTACATCAAGAACCACATCGATCCGACCCTGACCTTCCGCCGCTCCTGC
CGCGAGGGCGTGTGCGGGTCGTGCGCCATGAACATCGGCGGCACCAATACGCTGGCCTGCACCAAGGGCATGGACGAAGT
GCTGGTGAAGGGCTCGGTGAACATCTACCCGCTGCCGCACATGGAAGTGGTGAAGGACCTCGTTCCCGACCTCACCCGCT
TTTACGCGCAGCACGCCTCGATCGAGCCGTGGCTCCAGACCGACTCCGCCGCGCCCGAGAAGGAGTGGCGCCAGTCGAAG
GAAGACCGCGAGCGGCTGGATGGCCTCTATGAGTGCATCCTGTGCGCCTGCTGCTCCACCTCCTGCCCGAGCTACTGGTG
GAACGGCGACCGCTACCTCGGCCCGGCGGCCCTGCTCCAGGCCAACCGCTGGCTGAAGGACAGCCGCGACGAGCGCACCG
GCGCCCGCCTCGACAATCTGGAAGACCCCTTCCGGCTCTACCGCTGCCACACCATCATGAACTGCGCGCAGGCCTGCCCG
AAGGGTCTCAACCCCGCCAAGGCCATCGCCGAAATCAAGAAGATGATGGTGGAACGCCAGATCTGA

Upstream 100 bases:

>100_bases
CCAAGAAGCGCGTGTACTGAGCCCCGCGTGACACTATCGGGCCGGCCCAGCGGGGCCGGCTCTCTCGCACGACCGGCGCA
GCCGACGATTGGGACGCACC

Downstream 100 bases:

>100_bases
CGGCGTTTCTCCGCCGCCCTTTCGCAGAACGCGCGCCCCGGTGGCGCGCGTTTTGTTTTGAGGCGCTCGGATGCATCCAC
CGACACCCGGACAAAGCAAA

Product: succinate dehydrogenase/fumarate reductase iron-sulfur protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 261; Mature: 260

Protein sequence:

>261_residues
MAEFTLPKNSQITKGKTWPKPQAAKKVTEFRVYRWNPDDGKNPSIDTYYVDREACGPMVLDGLIYIKNHIDPTLTFRRSC
REGVCGSCAMNIGGTNTLACTKGMDEVLVKGSVNIYPLPHMEVVKDLVPDLTRFYAQHASIEPWLQTDSAAPEKEWRQSK
EDRERLDGLYECILCACCSTSCPSYWWNGDRYLGPAALLQANRWLKDSRDERTGARLDNLEDPFRLYRCHTIMNCAQACP
KGLNPAKAIAEIKKMMVERQI

Sequences:

>Translated_261_residues
MAEFTLPKNSQITKGKTWPKPQAAKKVTEFRVYRWNPDDGKNPSIDTYYVDREACGPMVLDGLIYIKNHIDPTLTFRRSC
REGVCGSCAMNIGGTNTLACTKGMDEVLVKGSVNIYPLPHMEVVKDLVPDLTRFYAQHASIEPWLQTDSAAPEKEWRQSK
EDRERLDGLYECILCACCSTSCPSYWWNGDRYLGPAALLQANRWLKDSRDERTGARLDNLEDPFRLYRCHTIMNCAQACP
KGLNPAKAIAEIKKMMVERQI
>Mature_260_residues
AEFTLPKNSQITKGKTWPKPQAAKKVTEFRVYRWNPDDGKNPSIDTYYVDREACGPMVLDGLIYIKNHIDPTLTFRRSCR
EGVCGSCAMNIGGTNTLACTKGMDEVLVKGSVNIYPLPHMEVVKDLVPDLTRFYAQHASIEPWLQTDSAAPEKEWRQSKE
DRERLDGLYECILCACCSTSCPSYWWNGDRYLGPAALLQANRWLKDSRDERTGARLDNLEDPFRLYRCHTIMNCAQACPK
GLNPAKAIAEIKKMMVERQI

Specific function: Two Distinct, Membrane-Bound, FAD-Containing Enzymes Are Responsible For The Catalysis Of Fumarate And Succinate Interconversion; The Fumarate Reductase Is Used In Anaerobic Growth, And The Succinate Dehydrogenase Is Used In Aerobic Growth. [C]

COG id: COG0479

COG function: function code C; Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 4Fe-4S ferredoxin-type domain [H]

Homologues:

Organism=Homo sapiens, GI115387094, Length=237, Percent_Identity=67.0886075949367, Blast_Score=336, Evalue=2e-92,
Organism=Escherichia coli, GI1786943, Length=235, Percent_Identity=51.9148936170213, Blast_Score=251, Evalue=4e-68,
Organism=Escherichia coli, GI1790596, Length=232, Percent_Identity=30.6034482758621, Blast_Score=118, Evalue=4e-28,
Organism=Caenorhabditis elegans, GI17533915, Length=239, Percent_Identity=60.2510460251046, Blast_Score=310, Evalue=4e-85,
Organism=Saccharomyces cerevisiae, GI6322987, Length=233, Percent_Identity=63.0901287553648, Blast_Score=303, Evalue=2e-83,
Organism=Drosophila melanogaster, GI17137106, Length=243, Percent_Identity=63.3744855967078, Blast_Score=337, Evalue=4e-93,
Organism=Drosophila melanogaster, GI24643156, Length=235, Percent_Identity=61.2765957446808, Blast_Score=306, Evalue=8e-84,

Paralogues:

None

Copy number: 480 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006058
- InterPro:   IPR017896
- InterPro:   IPR017900
- InterPro:   IPR012675
- InterPro:   IPR001041
- InterPro:   IPR012285
- InterPro:   IPR009051
- InterPro:   IPR004489 [H]

Pfam domain/function: NA

EC number: =1.3.99.1 [H]

Molecular weight: Translated: 29690; Mature: 29559

Theoretical pI: Translated: 7.95; Mature: 7.95

Prosite motif: PS00197 2FE2S_FER_1 ; PS00198 4FE4S_FERREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

5.0 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
8.0 %Cys+Met (Translated Protein)
5.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
7.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAEFTLPKNSQITKGKTWPKPQAAKKVTEFRVYRWNPDDGKNPSIDTYYVDREACGPMVL
CCCCCCCCCCCCCCCCCCCCCHHHHHHHHHEEEEECCCCCCCCCCCEEEECHHHCCHHHH
DGLIYIKNHIDPTLTFRRSCREGVCGSCAMNIGGTNTLACTKGMDEVLVKGSVNIYPLPH
HHHHHHHHCCCHHHHHHHHHHCCCCCHHEECCCCCCCEEECCCHHHHHHCCCCEEEECCH
MEVVKDLVPDLTRFYAQHASIEPWLQTDSAAPEKEWRQSKEDRERLDGLYECILCACCST
HHHHHHHHHHHHHHHHHHCCCCCHHCCCCCCCHHHHHHCHHHHHHHHHHHHHHHHHHHCC
SCPSYWWNGDRYLGPAALLQANRWLKDSRDERTGARLDNLEDPFRLYRCHTIMNCAQACP
CCCCCCCCCCCEECHHHHHHHHHHHHCCCCHHCCCHHCCCCCHHHHHHHHHHHHHHHHCC
KGLNPAKAIAEIKKMMVERQI
CCCCHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
AEFTLPKNSQITKGKTWPKPQAAKKVTEFRVYRWNPDDGKNPSIDTYYVDREACGPMVL
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHEEEEECCCCCCCCCCCEEEECHHHCCHHHH
DGLIYIKNHIDPTLTFRRSCREGVCGSCAMNIGGTNTLACTKGMDEVLVKGSVNIYPLPH
HHHHHHHHCCCHHHHHHHHHHCCCCCHHEECCCCCCCEEECCCHHHHHHCCCCEEEECCH
MEVVKDLVPDLTRFYAQHASIEPWLQTDSAAPEKEWRQSKEDRERLDGLYECILCACCST
HHHHHHHHHHHHHHHHHHCCCCCHHCCCCCCCHHHHHHCHHHHHHHHHHHHHHHHHHHCC
SCPSYWWNGDRYLGPAALLQANRWLKDSRDERTGARLDNLEDPFRLYRCHTIMNCAQACP
CCCCCCCCCCCEECHHHHHHHHHHHHCCCCHHCCCHHCCCCCHHHHHHHHHHHHHHHHCC
KGLNPAKAIAEIKKMMVERQI
CCCCHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA