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The map label for this gene is cysW [H]

Identifier: 158425358

GI number: 158425358

Start: 4286204

End: 4287070

Strand: Direct

Name: cysW [H]

Synonym: AZC_3734

Alternate gene names: 158425358

Gene position: 4286204-4287070 (Clockwise)

Preceding gene: 158425357

Following gene: 158425360

Centisome position: 79.82

GC content: 68.63

Gene sequence:

>867_bases
ATGTCGGACACCTCCACCCGCCGCCGCGTCGGCGACGGCCCGCTCGCCCGCCGCCTCATCATCGGCCTCGTGCTGCTGGT
TACGGTGCTCGTTCTGCTGGTGCCGCTCGCCTCCATCTTCACGGAAGCTTTCCAGCGCGGGGTACCCGCCTATTTCGCCG
CGCTGTCGCAGCCGGACACGCTGCACGCCATGGGGCTCACGGCCTTCACGGCACTGGTCTGCGTGCCCGTCAATGTGATC
TTCGGCATCGCCGCCGCCTGGACGGTGGCGAAGTTCACCTTTCCCGGCCGTGGCCTGCTGCTGGCGCTGATCGAGCTGCC
CTTTTCCATCTCGCCCATCGTGGCGGGCGTCGCCTATCTCTTCGTCTATGGCGCGCAGGGGCTGCTCGGGCCGTTTCTGG
AAGCCTACGACATCAAGATCATGTTCGCCGTGCCGGCGATCATCCTCGCCAGCCTGTTCGTCACCGCGCCGTTCGTCGCC
CGCGAAATCGTGCCGCTGATGATGGCGCAGGGGCGCGAGGAGGAAGAGGCGGCGGTGACGCTCGGCGCCTCCGGCTGGCG
CATCCTGCGCACCGTCACGCTGCCCAACGTGCGCTTCGCGTTGCTCTATGGCGCGGCGCTCTGCAACGCCCGAGTGATGG
GCGAGTTCGGCGCCGTCTCGGTGGTGTCCGGCAATATCCGGGGCCGCACCTCCACCCTGCCGCTCCAGATCGAGCTGCTC
TATCAGGACAGCCAGGTGGCCGGCGCTTTTGCCGCCGCCACCGTTCTGGCGGGCGTCGCCCTCGTCACGCTGGTCGCCAA
GCTCATCATCGAGCGCCTCGACGCCGAGCGCGAGCGGCTGAACGTGAAGCGGGGCGTCGGCCACTGA

Upstream 100 bases:

>100_bases
ATTGCCGCCACCATGCTCGGCCTCGCGTTTCTCCTGCTGCTGACGGTGAACGCCATTCAGGCCTGGCACCAGCGCCGCGC
GATCCGGGAGGACTGATCCC

Downstream 100 bases:

>100_bases
GCCCGCTCACGCGGTGATGGCCACCGGCAAGCCATAGCGGTCGCGCTCGGGCGGATCGGGAAAGACCAGCGCCGCCCCGC
GGGCGATGCGAGCCGCTGTC

Product: sulfate ABC transporter permease

Products: ADP; phosphate; S2O32- [Cytoplasm]; SO42- [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 288; Mature: 287

Protein sequence:

>288_residues
MSDTSTRRRVGDGPLARRLIIGLVLLVTVLVLLVPLASIFTEAFQRGVPAYFAALSQPDTLHAMGLTAFTALVCVPVNVI
FGIAAAWTVAKFTFPGRGLLLALIELPFSISPIVAGVAYLFVYGAQGLLGPFLEAYDIKIMFAVPAIILASLFVTAPFVA
REIVPLMMAQGREEEEAAVTLGASGWRILRTVTLPNVRFALLYGAALCNARVMGEFGAVSVVSGNIRGRTSTLPLQIELL
YQDSQVAGAFAAATVLAGVALVTLVAKLIIERLDAERERLNVKRGVGH

Sequences:

>Translated_288_residues
MSDTSTRRRVGDGPLARRLIIGLVLLVTVLVLLVPLASIFTEAFQRGVPAYFAALSQPDTLHAMGLTAFTALVCVPVNVI
FGIAAAWTVAKFTFPGRGLLLALIELPFSISPIVAGVAYLFVYGAQGLLGPFLEAYDIKIMFAVPAIILASLFVTAPFVA
REIVPLMMAQGREEEEAAVTLGASGWRILRTVTLPNVRFALLYGAALCNARVMGEFGAVSVVSGNIRGRTSTLPLQIELL
YQDSQVAGAFAAATVLAGVALVTLVAKLIIERLDAERERLNVKRGVGH
>Mature_287_residues
SDTSTRRRVGDGPLARRLIIGLVLLVTVLVLLVPLASIFTEAFQRGVPAYFAALSQPDTLHAMGLTAFTALVCVPVNVIF
GIAAAWTVAKFTFPGRGLLLALIELPFSISPIVAGVAYLFVYGAQGLLGPFLEAYDIKIMFAVPAIILASLFVTAPFVAR
EIVPLMMAQGREEEEAAVTLGASGWRILRTVTLPNVRFALLYGAALCNARVMGEFGAVSVVSGNIRGRTSTLPLQIELLY
QDSQVAGAFAAATVLAGVALVTLVAKLIIERLDAERERLNVKRGVGH

Specific function: Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG4208

COG function: function code P; ABC-type sulfate transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI87082099, Length=291, Percent_Identity=48.7972508591065, Blast_Score=296, Evalue=8e-82,
Organism=Escherichia coli, GI1788764, Length=212, Percent_Identity=36.3207547169811, Blast_Score=133, Evalue=1e-32,
Organism=Escherichia coli, GI1786980, Length=228, Percent_Identity=30.7017543859649, Blast_Score=80, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515
- InterPro:   IPR011866
- InterPro:   IPR005667 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 30664; Mature: 30533

Theoretical pI: Translated: 9.46; Mature: 9.46

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDTSTRRRVGDGPLARRLIIGLVLLVTVLVLLVPLASIFTEAFQRGVPAYFAALSQPDT
CCCCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCCH
LHAMGLTAFTALVCVPVNVIFGIAAAWTVAKFTFPGRGLLLALIELPFSISPIVAGVAYL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCHHHHHHHHHHH
FVYGAQGLLGPFLEAYDIKIMFAVPAIILASLFVTAPFVAREIVPLMMAQGREEEEAAVT
HHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHEEE
LGASGWRILRTVTLPNVRFALLYGAALCNARVMGEFGAVSVVSGNIRGRTSTLPLQIELL
ECCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCEEEEEE
YQDSQVAGAFAAATVLAGVALVTLVAKLIIERLDAERERLNVKRGVGH
EECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCC
>Mature Secondary Structure 
SDTSTRRRVGDGPLARRLIIGLVLLVTVLVLLVPLASIFTEAFQRGVPAYFAALSQPDT
CCCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCCH
LHAMGLTAFTALVCVPVNVIFGIAAAWTVAKFTFPGRGLLLALIELPFSISPIVAGVAYL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCHHHHHHHHHHH
FVYGAQGLLGPFLEAYDIKIMFAVPAIILASLFVTAPFVAREIVPLMMAQGREEEEAAVT
HHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHEEE
LGASGWRILRTVTLPNVRFALLYGAALCNARVMGEFGAVSVVSGNIRGRTSTLPLQIELL
ECCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCEEEEEE
YQDSQVAGAFAAATVLAGVALVTLVAKLIIERLDAERERLNVKRGVGH
EECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; S2O32- [Periplasm]; H2O; SO42- [Periplasm]; ATP [C]

Specific reaction: ATP + S2O32- [Periplasm] + H2O = ADP + phosphate + S2O32- [Cytoplasm] SO42- [Periplasm] + H2O + ATP = SO42- [Cytoplasm] + phosphate + ADP [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]