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The map label for this gene is cat1 [H]

Identifier: 158425352

GI number: 158425352

Start: 4278415

End: 4280397

Strand: Direct

Name: cat1 [H]

Synonym: AZC_3728

Alternate gene names: 158425352

Gene position: 4278415-4280397 (Clockwise)

Preceding gene: 158425349

Following gene: 158425356

Centisome position: 79.68

GC content: 63.69

Gene sequence:

>1983_bases
GTGATCAACGTGTTAAGACACGTTAAAATCATCGAATACCGAAATAGATGGCGCTTCCGGTCTGCACGATACGCGGTTTA
TATTTATCCCACCGCATATCCTTCGCGGGAAATGGCGAAGCTTAGCCGGCACTTTCGCCGATCGCCGCTCCGACAACGCG
AGCACAGACCTGTTCCAGCTTGGCCGTGCCACGGGAGCGCCACGAAGTGCACTTGGGGCACCGATCGAACCACTTGGTTC
GATGGCCGGAACGCCCCGACCTTCCCCAGAGATGCATGCCCCAAAGACGCGGGTTTTCAGCTCCGATACCGCCAAGGCAT
CCCATGGCCGAGCTTCAGCCATGCACCAAGCGCATACCAACGCGACCTTCGTGCAATTCCGAGGTCGCGGCCCTGCGACC
TATGGTGTTTCTCAAGTGCATATTCCTCAGGAAACGCCGAAAGAGACGCCATGACCGAACTTCCCGCCGCCGCCCATGAT
CGCATCCGCCTGTCCTCGCTGCTCGACAAGGTGGTCTCCGCCGAGGAGGCCGCCAGCCACATCAAGGACGGCATGATGGT
GGGCATGAGCGGCTTCACCCGCGCGGGGGAGGCCAAGGCCGTGCCCATGGCGCTCGCCGCCCGCGCCAAGACCGAGCCGT
TCAAGATCACCCTCGTCACCGGCGCCTCGCTCGGCAACGATCTCGACAAGCAGCTGGCGGAGGCACATGTCCTGGCCCGG
CGCCTGCCGTTCCAGTCGGACCCCGCCCTGCGCAAGGCCATCAATGCCGGCGAGGTGATGTTCATCGACCAGCATCTGTC
GGAAACCGTCGAGCACCTGCGCACCCACCAGCTCGGCCCCATCAACGTGGCGGTGGTGGAGGCGGTCGGCATCACGGCGC
AGGGCGGCATCATCCCCACCACGTCGGTGGGCAATTCCGCTTCCTTCGCCATCCTGGCGGAGAAGGTGATCGTCGAGATC
AACACCTCCCAGCCCATGGGGCTGGAGGGCCTGCACGACATCTATATCCCGACGCGCCGCCCCTTCCGCGAACCCATTCC
AGTGGTCGGTGCCGAGAGCCGGGTGGGCCTGCCCTTCATTCCGGTGCCGCCGGAGAAGATCGCGGCCATCGTCATCACCT
CGAAGCTCGATTCCGCCTCGAACGTGTTGCCGCCCGATGCGGAGACCGCCGCCATCGCCGGGCATCTCATGGAGTTCCTC
GGCCATGAGGTGAAGAAGGGCCGTCTCACCGAGCGCCTTCAGCCGCTTCAGGCCGGCATCGGCACCATTGCGAACGCGGT
GATGCATGGCTTCATCGAGAGCCCCTTCTACGACCTCACCATGTATTCCGAGGTTCTACAGGATTCGACCTTCGACCTGT
TCGATGCGGGCAAGCTCAACTTCGCCTCCGGCTCGTCCATCACCCTCTCGAAGCCCAAGTATGAGCAGGTGATGGCCGAC
ATCACCCGCTACAAGCCGCGCCTCATCCTGCGCCCGCAGGAGATTTCCAACCATCCGGAGATCATCCGCCGCCTTGGCAT
CATCGCCATCAACACGGCGCTGGAATTCGACATCTACGGCAACGTCAATTCCACCCACGTGGGCGGCACGCAGATGATGA
ACGGCATCGGCGGCTCGGGCGATTTTGCCCGCAACGGCTATCTGTCCGTGTTCGTCACCAAGTCCATCGCCAAGGACGGC
GCGCTGTCCTCCGTTGTACCCATGGTGAGCCACGTGGACCATACCGAGCATGACGTGGACATCGTGGTGACGGAAGTGGG
CCTTGCGGACCTGCGCGAACTCGCCCCGCGTGAACGCGCTCGCGTCATCATCGACAACTGCGTCCACCCGCTCTATCGCG
ACGCGCTCGACGACTATTTCCAGCGCGCCCTCGCCCGCGGCGGCCACACGCCCCACCTCATCGAGGAGGCCTTCTCCTGG
CACGTGCGGGCGCGGGAAACGGGGCGCATGCTGGCTCCGCCCCACCTCGCAGCGTCAGCCTGA

Upstream 100 bases:

>100_bases
TACCCCCGAGCCATTGGTCTACAGGAGGAGCCGCAGGATTCCTGTTGCACAATCGCCACATTGAACAGAAGAGAACCCAG
TACCACCAAGTCACCAAGGC

Downstream 100 bases:

>100_bases
GGCGCGTCACACCAGCGCCAGATCCTTCGGGGTGACATTGGCGAAGACGCGGCCGAGGCTGGCCGCGTCGAGGCCATAAA
GCTGGCGGATGAGACCGCCC

Product: acetyl-CoA hydrolase

Products: propionate; succinyl-CoA [C]

Alternate protein names: NA

Number of amino acids: Translated: 660; Mature: 660

Protein sequence:

>660_residues
MINVLRHVKIIEYRNRWRFRSARYAVYIYPTAYPSREMAKLSRHFRRSPLRQREHRPVPAWPCHGSATKCTWGTDRTTWF
DGRNAPTFPRDACPKDAGFQLRYRQGIPWPSFSHAPSAYQRDLRAIPRSRPCDLWCFSSAYSSGNAERDAMTELPAAAHD
RIRLSSLLDKVVSAEEAASHIKDGMMVGMSGFTRAGEAKAVPMALAARAKTEPFKITLVTGASLGNDLDKQLAEAHVLAR
RLPFQSDPALRKAINAGEVMFIDQHLSETVEHLRTHQLGPINVAVVEAVGITAQGGIIPTTSVGNSASFAILAEKVIVEI
NTSQPMGLEGLHDIYIPTRRPFREPIPVVGAESRVGLPFIPVPPEKIAAIVITSKLDSASNVLPPDAETAAIAGHLMEFL
GHEVKKGRLTERLQPLQAGIGTIANAVMHGFIESPFYDLTMYSEVLQDSTFDLFDAGKLNFASGSSITLSKPKYEQVMAD
ITRYKPRLILRPQEISNHPEIIRRLGIIAINTALEFDIYGNVNSTHVGGTQMMNGIGGSGDFARNGYLSVFVTKSIAKDG
ALSSVVPMVSHVDHTEHDVDIVVTEVGLADLRELAPRERARVIIDNCVHPLYRDALDDYFQRALARGGHTPHLIEEAFSW
HVRARETGRMLAPPHLAASA

Sequences:

>Translated_660_residues
MINVLRHVKIIEYRNRWRFRSARYAVYIYPTAYPSREMAKLSRHFRRSPLRQREHRPVPAWPCHGSATKCTWGTDRTTWF
DGRNAPTFPRDACPKDAGFQLRYRQGIPWPSFSHAPSAYQRDLRAIPRSRPCDLWCFSSAYSSGNAERDAMTELPAAAHD
RIRLSSLLDKVVSAEEAASHIKDGMMVGMSGFTRAGEAKAVPMALAARAKTEPFKITLVTGASLGNDLDKQLAEAHVLAR
RLPFQSDPALRKAINAGEVMFIDQHLSETVEHLRTHQLGPINVAVVEAVGITAQGGIIPTTSVGNSASFAILAEKVIVEI
NTSQPMGLEGLHDIYIPTRRPFREPIPVVGAESRVGLPFIPVPPEKIAAIVITSKLDSASNVLPPDAETAAIAGHLMEFL
GHEVKKGRLTERLQPLQAGIGTIANAVMHGFIESPFYDLTMYSEVLQDSTFDLFDAGKLNFASGSSITLSKPKYEQVMAD
ITRYKPRLILRPQEISNHPEIIRRLGIIAINTALEFDIYGNVNSTHVGGTQMMNGIGGSGDFARNGYLSVFVTKSIAKDG
ALSSVVPMVSHVDHTEHDVDIVVTEVGLADLRELAPRERARVIIDNCVHPLYRDALDDYFQRALARGGHTPHLIEEAFSW
HVRARETGRMLAPPHLAASA
>Mature_660_residues
MINVLRHVKIIEYRNRWRFRSARYAVYIYPTAYPSREMAKLSRHFRRSPLRQREHRPVPAWPCHGSATKCTWGTDRTTWF
DGRNAPTFPRDACPKDAGFQLRYRQGIPWPSFSHAPSAYQRDLRAIPRSRPCDLWCFSSAYSSGNAERDAMTELPAAAHD
RIRLSSLLDKVVSAEEAASHIKDGMMVGMSGFTRAGEAKAVPMALAARAKTEPFKITLVTGASLGNDLDKQLAEAHVLAR
RLPFQSDPALRKAINAGEVMFIDQHLSETVEHLRTHQLGPINVAVVEAVGITAQGGIIPTTSVGNSASFAILAEKVIVEI
NTSQPMGLEGLHDIYIPTRRPFREPIPVVGAESRVGLPFIPVPPEKIAAIVITSKLDSASNVLPPDAETAAIAGHLMEFL
GHEVKKGRLTERLQPLQAGIGTIANAVMHGFIESPFYDLTMYSEVLQDSTFDLFDAGKLNFASGSSITLSKPKYEQVMAD
ITRYKPRLILRPQEISNHPEIIRRLGIIAINTALEFDIYGNVNSTHVGGTQMMNGIGGSGDFARNGYLSVFVTKSIAKDG
ALSSVVPMVSHVDHTEHDVDIVVTEVGLADLRELAPRERARVIIDNCVHPLYRDALDDYFQRALARGGHTPHLIEEAFSW
HVRARETGRMLAPPHLAASA

Specific function: Forms succinyl-CoA from succinate and acetyl-CoA [H]

COG id: COG0427

COG function: function code C; Acetyl-CoA hydrolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acetyl-CoA hydrolase/transferase family [H]

Homologues:

Organism=Escherichia coli, GI1789287, Length=487, Percent_Identity=44.9691991786448, Blast_Score=411, Evalue=1e-116,
Organism=Caenorhabditis elegans, GI32563853, Length=225, Percent_Identity=28, Blast_Score=67, Evalue=4e-11,
Organism=Saccharomyces cerevisiae, GI6319456, Length=510, Percent_Identity=43.3333333333333, Blast_Score=401, Evalue=1e-112,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003702
- InterPro:   IPR006472
- InterPro:   IPR017821 [H]

Pfam domain/function: PF02550 AcetylCoA_hydro; PF04223 CitF [H]

EC number: NA

Molecular weight: Translated: 72856; Mature: 72856

Theoretical pI: Translated: 8.71; Mature: 8.71

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MINVLRHVKIIEYRNRWRFRSARYAVYIYPTAYPSREMAKLSRHFRRSPLRQREHRPVPA
CCCHHHHHHHHHHHCCCEECCCCEEEEEEECCCCCHHHHHHHHHHHHCHHHHHHCCCCCC
WPCHGSATKCTWGTDRTTWFDGRNAPTFPRDACPKDAGFQLRYRQGIPWPSFSHAPSAYQ
CCCCCCCCEEECCCCCCEEECCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCHHHH
RDLRAIPRSRPCDLWCFSSAYSSGNAERDAMTELPAAAHDRIRLSSLLDKVVSAEEAASH
HHHHHCCCCCCCCEEEEHHHHCCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHH
IKDGMMVGMSGFTRAGEAKAVPMALAARAKTEPFKITLVTGASLGNDLDKQLAEAHVLAR
HHCCEEECCCCCCCCCCCCCCHHHHHHHCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHH
RLPFQSDPALRKAINAGEVMFIDQHLSETVEHLRTHQLGPINVAVVEAVGITAQGGIIPT
HCCCCCCHHHHHHCCCCCEEEEHHHHHHHHHHHHHCCCCCCEEEEEEEECEEECCCEEEC
TSVGNSASFAILAEKVIVEINTSQPMGLEGLHDIYIPTRRPFREPIPVVGAESRVGLPFI
CCCCCCCHHHEEEEEEEEEECCCCCCCCCCCHHEECCCCCCCCCCCCCCCCCCCCCCCCC
PVPPEKIAAIVITSKLDSASNVLPPDAETAAIAGHLMEFLGHEVKKGRLTERLQPLQAGI
CCCHHHEEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHH
GTIANAVMHGFIESPFYDLTMYSEVLQDSTFDLFDAGKLNFASGSSITLSKPKYEQVMAD
HHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCEECCCCEEECCCCEEEECCCHHHHHHHH
ITRYKPRLILRPQEISNHPEIIRRLGIIAINTALEFDIYGNVNSTHVGGTQMMNGIGGSG
HHHCCCEEEECHHHHCCCHHHHHHHCEEEEEEEEEEEEECCCCCCCCCHHHHHHCCCCCC
DFARNGYLSVFVTKSIAKDGALSSVVPMVSHVDHTEHDVDIVVTEVGLADLRELAPRERA
CCCCCCEEEEEEEHHHHCCCCHHHHHHHHHHCCCCCCCCEEEEEECCHHHHHHHCCHHHH
RVIIDNCVHPLYRDALDDYFQRALARGGHTPHLIEEAFSWHVRARETGRMLAPPHLAASA
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHEECCCCCCCCCCCCCCCC
>Mature Secondary Structure
MINVLRHVKIIEYRNRWRFRSARYAVYIYPTAYPSREMAKLSRHFRRSPLRQREHRPVPA
CCCHHHHHHHHHHHCCCEECCCCEEEEEEECCCCCHHHHHHHHHHHHCHHHHHHCCCCCC
WPCHGSATKCTWGTDRTTWFDGRNAPTFPRDACPKDAGFQLRYRQGIPWPSFSHAPSAYQ
CCCCCCCCEEECCCCCCEEECCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCHHHH
RDLRAIPRSRPCDLWCFSSAYSSGNAERDAMTELPAAAHDRIRLSSLLDKVVSAEEAASH
HHHHHCCCCCCCCEEEEHHHHCCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHH
IKDGMMVGMSGFTRAGEAKAVPMALAARAKTEPFKITLVTGASLGNDLDKQLAEAHVLAR
HHCCEEECCCCCCCCCCCCCCHHHHHHHCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHH
RLPFQSDPALRKAINAGEVMFIDQHLSETVEHLRTHQLGPINVAVVEAVGITAQGGIIPT
HCCCCCCHHHHHHCCCCCEEEEHHHHHHHHHHHHHCCCCCCEEEEEEEECEEECCCEEEC
TSVGNSASFAILAEKVIVEINTSQPMGLEGLHDIYIPTRRPFREPIPVVGAESRVGLPFI
CCCCCCCHHHEEEEEEEEEECCCCCCCCCCCHHEECCCCCCCCCCCCCCCCCCCCCCCCC
PVPPEKIAAIVITSKLDSASNVLPPDAETAAIAGHLMEFLGHEVKKGRLTERLQPLQAGI
CCCHHHEEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHH
GTIANAVMHGFIESPFYDLTMYSEVLQDSTFDLFDAGKLNFASGSSITLSKPKYEQVMAD
HHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCEECCCCEEECCCCEEEECCCHHHHHHHH
ITRYKPRLILRPQEISNHPEIIRRLGIIAINTALEFDIYGNVNSTHVGGTQMMNGIGGSG
HHHCCCEEEECHHHHCCCHHHHHHHCEEEEEEEEEEEEECCCCCCCCCHHHHHHCCCCCC
DFARNGYLSVFVTKSIAKDGALSSVVPMVSHVDHTEHDVDIVVTEVGLADLRELAPRERA
CCCCCCEEEEEEEHHHHCCCCHHHHHHHHHHCCCCCCCCEEEEEECCHHHHHHHCCHHHH
RVIIDNCVHPLYRDALDDYFQRALARGGHTPHLIEEAFSWHVRARETGRMLAPPHLAASA
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHEECCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: propionyl-CoA; succinate [C]

Specific reaction: propionyl-CoA + succinate = propionate + succinyl-CoA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8550525 [H]