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The map label for this gene is yleA [C]

Identifier: 158425333

GI number: 158425333

Start: 4255260

End: 4256549

Strand: Reverse

Name: yleA [C]

Synonym: AZC_3709

Alternate gene names: 158425333

Gene position: 4256549-4255260 (Counterclockwise)

Preceding gene: 158425334

Following gene: 158425332

Centisome position: 79.27

GC content: 71.94

Gene sequence:

>1290_bases
ATGGGGCAGGCGGGCGCGCGGGAGACGGAAGGCGTCGAGGTCGTCACCTTCGGCTGCCGGCTGAACACGCTCGACGGCGC
CGAGATCCAGCGCGCCGCCACCGCCGCCGGCCTCACCCGCACCGTGATCGTCAATTCCTGCGCCGTCACGGCGGAAGCGG
TGCGCCAGGCCCGCCAGAGCATCCGCCGCCTCAAGCGGGCCGATCCGGCGCTGAAGGTCGTTGTCACCGGCTGCGCCGCC
CAGACCGAGCCCCAGACCTTCGCCACCATGCCGGAAGTGGACCGCGTGGTGGGGAACGGCGCCAAGGGCGCAGTTGAGAC
CTGGGCCGAGGCCCGCGCCGCCTTCGATTTCGGCGTCAGCGCCGAGGAAAAGGTGAAGGTGGACGACATCTTCGCCGTGC
GCGAGACCGCCCTCCACATGGTGGACGGCATGGACGGGCGCACCCGCGCCTTCGTGCAGGTGCAGAACGGCTGCGACCAC
CGCTGCACCTTCTGCATCATCCCCTATGGTCGGGGCGCCTCCCGCTCGGTGCCCATGGGCGACGTGGTGGCCCACATCCG
CGCGCTGGCCGAAGGCGGGCAGAAGGAAGTGGTGCTCACGGGCGTCGACCTCACCTCCTATGGTGCGGACCTGCCCGGCG
CGCCGACTCTCGGGCGGCTGGTGCGCGCCATTCTGCGGCAGGTGCCGGAGCTGGAGCGCCTGCGCCTCTCCTCCATCGAC
AGCGTGGAGGCGGATGCCGACCTCCTGCGCGCGCTGGCGGAAGAGGAGCGGCTGATGCCGCATCTGCATCTCTCGCTGCA
ATCGGGCGACGACATGATCCTGAAGCGCATGAAGCGCCGCCATTCGCGGGCGCAGGTGATCGCGCTCGTGGAAGAGATGC
GCCGCCTGCGGCCGGATCTCGTGCTGGGCGCGGACCTCATTGCCGGCTTTCCCACCGAGACGGAAGCCATGTTCCGCAAC
TCGCTCTCCATCGTGGACGCGTGCGGCCTGAGCTTCCTCCACGTCTTTCCCTTCTCCGCCCGCGCCGGCACGCCCGCCGC
GCGCATGCCGCCGGTGCCGGGCGACGTGGTGGATGCCCGCGCCCGCCGCCTGCGGGAGAAGGGCGAGGAGGCGCTGCGGC
GGCATCTGGCCGCCGAGATCGGCCGCCGCCATCCCGTGCTCGTGGAGCGCGGCGGCATCGGTCGCACCCCCTATTTCACG
CCGGTGCGCCTGCACCGGGCGGCGCAGCCCGGCGCCGTGATCGATCTGCGCATCGCCGGGCACGACGGCGCGCGTCTGGT
GGCCGCATGA

Upstream 100 bases:

>100_bases
ACTGGCGCGCCAGCGACGGCCACGTGCTGATGACCGGCCCGGTGGCGCTGGAATTCACCGGCACGCTCACCTCCGACATG
ATCACCGAGGCCGCCTGAGC

Downstream 100 bases:

>100_bases
GCGAGACCTCTCCCCCCGAAAAACCCGGCTTCTGGCGCCGCCTGACCTCCGGTCTCGCGCGCACGGCCACTTCCCTCACC
CAGGGGATCACGGACCTCGT

Product: MiaB-like tRNA modifying enzyme

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 429; Mature: 428

Protein sequence:

>429_residues
MGQAGARETEGVEVVTFGCRLNTLDGAEIQRAATAAGLTRTVIVNSCAVTAEAVRQARQSIRRLKRADPALKVVVTGCAA
QTEPQTFATMPEVDRVVGNGAKGAVETWAEARAAFDFGVSAEEKVKVDDIFAVRETALHMVDGMDGRTRAFVQVQNGCDH
RCTFCIIPYGRGASRSVPMGDVVAHIRALAEGGQKEVVLTGVDLTSYGADLPGAPTLGRLVRAILRQVPELERLRLSSID
SVEADADLLRALAEEERLMPHLHLSLQSGDDMILKRMKRRHSRAQVIALVEEMRRLRPDLVLGADLIAGFPTETEAMFRN
SLSIVDACGLSFLHVFPFSARAGTPAARMPPVPGDVVDARARRLREKGEEALRRHLAAEIGRRHPVLVERGGIGRTPYFT
PVRLHRAAQPGAVIDLRIAGHDGARLVAA

Sequences:

>Translated_429_residues
MGQAGARETEGVEVVTFGCRLNTLDGAEIQRAATAAGLTRTVIVNSCAVTAEAVRQARQSIRRLKRADPALKVVVTGCAA
QTEPQTFATMPEVDRVVGNGAKGAVETWAEARAAFDFGVSAEEKVKVDDIFAVRETALHMVDGMDGRTRAFVQVQNGCDH
RCTFCIIPYGRGASRSVPMGDVVAHIRALAEGGQKEVVLTGVDLTSYGADLPGAPTLGRLVRAILRQVPELERLRLSSID
SVEADADLLRALAEEERLMPHLHLSLQSGDDMILKRMKRRHSRAQVIALVEEMRRLRPDLVLGADLIAGFPTETEAMFRN
SLSIVDACGLSFLHVFPFSARAGTPAARMPPVPGDVVDARARRLREKGEEALRRHLAAEIGRRHPVLVERGGIGRTPYFT
PVRLHRAAQPGAVIDLRIAGHDGARLVAA
>Mature_428_residues
GQAGARETEGVEVVTFGCRLNTLDGAEIQRAATAAGLTRTVIVNSCAVTAEAVRQARQSIRRLKRADPALKVVVTGCAAQ
TEPQTFATMPEVDRVVGNGAKGAVETWAEARAAFDFGVSAEEKVKVDDIFAVRETALHMVDGMDGRTRAFVQVQNGCDHR
CTFCIIPYGRGASRSVPMGDVVAHIRALAEGGQKEVVLTGVDLTSYGADLPGAPTLGRLVRAILRQVPELERLRLSSIDS
VEADADLLRALAEEERLMPHLHLSLQSGDDMILKRMKRRHSRAQVIALVEEMRRLRPDLVLGADLIAGFPTETEAMFRNS
LSIVDACGLSFLHVFPFSARAGTPAARMPPVPGDVVDARARRLREKGEEALRRHLAAEIGRRHPVLVERGGIGRTPYFTP
VRLHRAAQPGAVIDLRIAGHDGARLVAA

Specific function: Unknown

COG id: COG0621

COG function: function code J; 2-methylthioadenine synthetase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 MTTase N-terminal domain [H]

Homologues:

Organism=Homo sapiens, GI93277076, Length=405, Percent_Identity=26.1728395061728, Blast_Score=126, Evalue=3e-29,
Organism=Homo sapiens, GI28872782, Length=411, Percent_Identity=24.330900243309, Blast_Score=114, Evalue=2e-25,
Organism=Homo sapiens, GI28872784, Length=411, Percent_Identity=24.330900243309, Blast_Score=114, Evalue=2e-25,
Organism=Escherichia coli, GI1786882, Length=415, Percent_Identity=28.433734939759, Blast_Score=149, Evalue=4e-37,
Organism=Escherichia coli, GI1787057, Length=404, Percent_Identity=27.970297029703, Blast_Score=135, Evalue=3e-33,
Organism=Caenorhabditis elegans, GI17553146, Length=437, Percent_Identity=27.2311212814645, Blast_Score=142, Evalue=4e-34,
Organism=Caenorhabditis elegans, GI71996771, Length=247, Percent_Identity=31.1740890688259, Blast_Score=108, Evalue=4e-24,
Organism=Drosophila melanogaster, GI21356207, Length=427, Percent_Identity=27.8688524590164, Blast_Score=148, Evalue=8e-36,
Organism=Drosophila melanogaster, GI19922432, Length=385, Percent_Identity=27.012987012987, Blast_Score=117, Evalue=1e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006638
- InterPro:   IPR005839
- InterPro:   IPR020612
- InterPro:   IPR013848
- InterPro:   IPR006467
- InterPro:   IPR007197 [H]

Pfam domain/function: PF04055 Radical_SAM; PF00919 UPF0004 [H]

EC number: NA

Molecular weight: Translated: 46396; Mature: 46265

Theoretical pI: Translated: 8.71; Mature: 8.71

Prosite motif: PS01278 UPF0004

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGQAGARETEGVEVVTFGCRLNTLDGAEIQRAATAAGLTRTVIVNSCAVTAEAVRQARQS
CCCCCCCCCCCEEEEEEEEEECCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHH
IRRLKRADPALKVVVTGCAAQTEPQTFATMPEVDRVVGNGAKGAVETWAEARAAFDFGVS
HHHHHHCCCCEEEEEECCCCCCCCCHHHCCCHHHHHHCCCCCHHHHHHHHHHHHHHCCCC
AEEKVKVDDIFAVRETALHMVDGMDGRTRAFVQVQNGCDHRCTFCIIPYGRGASRSVPMG
CCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCEEEEEEECCCCCCCCCCHH
DVVAHIRALAEGGQKEVVLTGVDLTSYGADLPGAPTLGRLVRAILRQVPELERLRLSSID
HHHHHHHHHHCCCCCEEEEEECCHHHCCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHCCC
SVEADADLLRALAEEERLMPHLHLSLQSGDDMILKRMKRRHSRAQVIALVEEMRRLRPDL
CCCCCHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
VLGADLIAGFPTETEAMFRNSLSIVDACGLSFLHVFPFSARAGTPAARMPPVPGDVVDAR
EECHHHHCCCCCHHHHHHHHCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHH
ARRLREKGEEALRRHLAAEIGRRHPVLVERGGIGRTPYFTPVRLHRAAQPGAVIDLRIAG
HHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCHHHHHHCCCCCCEEEEEEEC
HDGARLVAA
CCCCEEECC
>Mature Secondary Structure 
GQAGARETEGVEVVTFGCRLNTLDGAEIQRAATAAGLTRTVIVNSCAVTAEAVRQARQS
CCCCCCCCCCEEEEEEEEEECCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHH
IRRLKRADPALKVVVTGCAAQTEPQTFATMPEVDRVVGNGAKGAVETWAEARAAFDFGVS
HHHHHHCCCCEEEEEECCCCCCCCCHHHCCCHHHHHHCCCCCHHHHHHHHHHHHHHCCCC
AEEKVKVDDIFAVRETALHMVDGMDGRTRAFVQVQNGCDHRCTFCIIPYGRGASRSVPMG
CCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCEEEEEEECCCCCCCCCCHH
DVVAHIRALAEGGQKEVVLTGVDLTSYGADLPGAPTLGRLVRAILRQVPELERLRLSSID
HHHHHHHHHHCCCCCEEEEEECCHHHCCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHCCC
SVEADADLLRALAEEERLMPHLHLSLQSGDDMILKRMKRRHSRAQVIALVEEMRRLRPDL
CCCCCHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
VLGADLIAGFPTETEAMFRNSLSIVDACGLSFLHVFPFSARAGTPAARMPPVPGDVVDAR
EECHHHHCCCCCHHHHHHHHCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHH
ARRLREKGEEALRRHLAAEIGRRHPVLVERGGIGRTPYFTPVRLHRAAQPGAVIDLRIAG
HHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCHHHHHHCCCCCCEEEEEEEC
HDGARLVAA
CCCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9823893 [H]