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The map label for this gene is rsmB [H]

Identifier: 158425326

GI number: 158425326

Start: 4247141

End: 4248442

Strand: Direct

Name: rsmB [H]

Synonym: AZC_3702

Alternate gene names: 158425326

Gene position: 4247141-4248442 (Clockwise)

Preceding gene: 158425325

Following gene: 158425327

Centisome position: 79.09

GC content: 71.74

Gene sequence:

>1302_bases
GTGACCCCTTCCGCCCGCCTGTCCGCCGCCATCGACATCCTCGCCGATATCATCGCCCGCCGCCGCCCGGCCGGCGATGC
CATCAAGGACTGGGGGCTCTCGCACCGCTTCGCCGGCTCCGGCGACCGCGCCGCACTGTCGGGCCTCATCTTCGACGCCC
TGCGCCGCCGCGCCTCCTGCGCTCATGTGATGGGCTCGGAAGAGCCGCGCGCCCTGCTGCTCGGGATGCTGGCCACCGTG
CGCGGGCTGGATGTGGACGCCATCGCCAAGCTCTGCGACGGCGCCCGCTTCGCCCCTGCCCCGCTCTCCGAGGACGAGCG
CACCCGCCTCGCCAGCCCTAGTCTGGAAGGCGCCGCTCCCTGGGTGCGCGGCGACTATCCCCAGTGGCTGGACGGCGAAC
TGAAGGCCATGTTCGGCGAGGAGCGTGTGGCCGAGGCCGAAGCGCTGGCCGCTCGCGCGCCCGTGGACATGCGCGTCAAC
ACGCTGAAGGCCAAGCCAGAAGAGGCGCTGGCGGAACTCGCCCATCTTCACCCCGAACCCGGCCAGTGGTCGCCCCTGGC
CCTGCGCATTCCGCTGGGGGCGGACGGCAAGCAGCCCCCCATCACATCCGAGCCCGCCTTCGTGAAGGGCGGCGTCGAAG
TGCAGGACGAAGGCTCGCAGATCGCCGCCATCCTCGCCGCCCCCATGCCCGGCTCTCAGGTTCTGGACCTGTGCGCGGGC
GCCGGCGGCAAGACGCTGGAACTGGCCGCCCTCATGGACAACAAGGGCCAGCTCTACGCCCATGACAGCGATGTGCGCCG
CCTGAAGCCCATCCACGAGCGCCTCCAGCGGGCCGGCGTGCGCAACGTGCAGATCCGCGCGCCGCGCGGCACGGCGGACG
TGCTCTCCGACCTCGAAGGCCACATGGACCTCGTGCTGGTGGACGCCCCCTGCACCGGCACCGGCACCTGGCGGCGCAAC
CCCGACGCCAAGTGGCGCGTGCGCCCCGGCGCGCTCGCCGAGCGCACCGCCGAGCAGGCGAAGATCCTCGAACAGGCTGT
GCGCTATGTGAAGCCAGGCGGGCGGCTCGCTTATGTCACCTGCTCGCTGCTCAACTCCGAGAATGCGGGGCAGATTCGCG
CCCTGCTGGAAAAGCACCCGGACTTCTCGGTGGTGCCCTCCACCGAAGCCGTTCTGGCACTCGGCAGCCGGGGCCTCGCC
CTGCGCCAGGCCGCGCTGGACCTGCCCGAGGGCCTCATGCTGACGCCCCGCCGCACGGGCACGGACGGCTTCTTCATCAG
CGTCCTGAAACGCGCAGCCTGA

Upstream 100 bases:

>100_bases
AATACCTGCACATCATCGACGAGAAGCTCGGCGCCGCGCTCGACCATTTCACCGAACAGCTGCGCGCCGGCACCCTGACC
CTCCCGAACCGGATTCCCGC

Downstream 100 bases:

>100_bases
ACGGGCCGCGCTCCGACGGCGTGTGGCCGCGCGTGAATACGTGACCATATTGACACGTGACAAAATGGAAACCTATTCTG
AGGGCATGGATGCGGTCTTC

Product: RNA methyltransferase

Products: NA

Alternate protein names: rRNA (cytosine-C(5)-)-methyltransferase rsmB [H]

Number of amino acids: Translated: 433; Mature: 432

Protein sequence:

>433_residues
MTPSARLSAAIDILADIIARRRPAGDAIKDWGLSHRFAGSGDRAALSGLIFDALRRRASCAHVMGSEEPRALLLGMLATV
RGLDVDAIAKLCDGARFAPAPLSEDERTRLASPSLEGAAPWVRGDYPQWLDGELKAMFGEERVAEAEALAARAPVDMRVN
TLKAKPEEALAELAHLHPEPGQWSPLALRIPLGADGKQPPITSEPAFVKGGVEVQDEGSQIAAILAAPMPGSQVLDLCAG
AGGKTLELAALMDNKGQLYAHDSDVRRLKPIHERLQRAGVRNVQIRAPRGTADVLSDLEGHMDLVLVDAPCTGTGTWRRN
PDAKWRVRPGALAERTAEQAKILEQAVRYVKPGGRLAYVTCSLLNSENAGQIRALLEKHPDFSVVPSTEAVLALGSRGLA
LRQAALDLPEGLMLTPRRTGTDGFFISVLKRAA

Sequences:

>Translated_433_residues
MTPSARLSAAIDILADIIARRRPAGDAIKDWGLSHRFAGSGDRAALSGLIFDALRRRASCAHVMGSEEPRALLLGMLATV
RGLDVDAIAKLCDGARFAPAPLSEDERTRLASPSLEGAAPWVRGDYPQWLDGELKAMFGEERVAEAEALAARAPVDMRVN
TLKAKPEEALAELAHLHPEPGQWSPLALRIPLGADGKQPPITSEPAFVKGGVEVQDEGSQIAAILAAPMPGSQVLDLCAG
AGGKTLELAALMDNKGQLYAHDSDVRRLKPIHERLQRAGVRNVQIRAPRGTADVLSDLEGHMDLVLVDAPCTGTGTWRRN
PDAKWRVRPGALAERTAEQAKILEQAVRYVKPGGRLAYVTCSLLNSENAGQIRALLEKHPDFSVVPSTEAVLALGSRGLA
LRQAALDLPEGLMLTPRRTGTDGFFISVLKRAA
>Mature_432_residues
TPSARLSAAIDILADIIARRRPAGDAIKDWGLSHRFAGSGDRAALSGLIFDALRRRASCAHVMGSEEPRALLLGMLATVR
GLDVDAIAKLCDGARFAPAPLSEDERTRLASPSLEGAAPWVRGDYPQWLDGELKAMFGEERVAEAEALAARAPVDMRVNT
LKAKPEEALAELAHLHPEPGQWSPLALRIPLGADGKQPPITSEPAFVKGGVEVQDEGSQIAAILAAPMPGSQVLDLCAGA
GGKTLELAALMDNKGQLYAHDSDVRRLKPIHERLQRAGVRNVQIRAPRGTADVLSDLEGHMDLVLVDAPCTGTGTWRRNP
DAKWRVRPGALAERTAEQAKILEQAVRYVKPGGRLAYVTCSLLNSENAGQIRALLEKHPDFSVVPSTEAVLALGSRGLAL
RQAALDLPEGLMLTPRRTGTDGFFISVLKRAA

Specific function: Unknown

COG id: COG0144

COG function: function code J; tRNA and rRNA cytosine-C5-methylases

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. RsmB/NOP family [H]

Homologues:

Organism=Homo sapiens, GI76150625, Length=317, Percent_Identity=30.5993690851735, Blast_Score=113, Evalue=4e-25,
Organism=Homo sapiens, GI76150623, Length=317, Percent_Identity=30.5993690851735, Blast_Score=113, Evalue=4e-25,
Organism=Homo sapiens, GI270288816, Length=244, Percent_Identity=33.1967213114754, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI23199998, Length=243, Percent_Identity=32.9218106995885, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI270288818, Length=243, Percent_Identity=32.9218106995885, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI8922322, Length=244, Percent_Identity=33.1967213114754, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI32698918, Length=199, Percent_Identity=32.1608040201005, Blast_Score=99, Evalue=8e-21,
Organism=Homo sapiens, GI11545785, Length=159, Percent_Identity=31.4465408805031, Blast_Score=69, Evalue=1e-11,
Organism=Homo sapiens, GI39995082, Length=312, Percent_Identity=26.6025641025641, Blast_Score=67, Evalue=3e-11,
Organism=Homo sapiens, GI301336155, Length=185, Percent_Identity=29.1891891891892, Blast_Score=66, Evalue=6e-11,
Organism=Escherichia coli, GI2367212, Length=258, Percent_Identity=33.7209302325581, Blast_Score=125, Evalue=5e-30,
Organism=Escherichia coli, GI87081985, Length=282, Percent_Identity=29.0780141843972, Blast_Score=102, Evalue=4e-23,
Organism=Caenorhabditis elegans, GI17536757, Length=319, Percent_Identity=29.153605015674, Blast_Score=115, Evalue=6e-26,
Organism=Caenorhabditis elegans, GI71998419, Length=308, Percent_Identity=26.9480519480519, Blast_Score=84, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI115534021, Length=228, Percent_Identity=29.8245614035088, Blast_Score=82, Evalue=5e-16,
Organism=Caenorhabditis elegans, GI25143471, Length=184, Percent_Identity=32.6086956521739, Blast_Score=73, Evalue=3e-13,
Organism=Saccharomyces cerevisiae, GI6324268, Length=317, Percent_Identity=26.4984227129338, Blast_Score=101, Evalue=2e-22,
Organism=Saccharomyces cerevisiae, GI6319447, Length=270, Percent_Identity=25.9259259259259, Blast_Score=74, Evalue=3e-14,
Organism=Drosophila melanogaster, GI22024126, Length=295, Percent_Identity=29.4915254237288, Blast_Score=107, Evalue=1e-23,
Organism=Drosophila melanogaster, GI21356579, Length=279, Percent_Identity=27.9569892473118, Blast_Score=86, Evalue=6e-17,
Organism=Drosophila melanogaster, GI24668781, Length=166, Percent_Identity=29.5180722891566, Blast_Score=71, Evalue=1e-12,
Organism=Drosophila melanogaster, GI21356513, Length=166, Percent_Identity=29.5180722891566, Blast_Score=71, Evalue=1e-12,
Organism=Drosophila melanogaster, GI21355201, Length=191, Percent_Identity=29.3193717277487, Blast_Score=69, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001678
- InterPro:   IPR018314
- InterPro:   IPR006027
- InterPro:   IPR004573 [H]

Pfam domain/function: PF01189 Nol1_Nop2_Fmu; PF01029 NusB [H]

EC number: NA

Molecular weight: Translated: 46326; Mature: 46194

Theoretical pI: Translated: 7.57; Mature: 7.57

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTPSARLSAAIDILADIIARRRPAGDAIKDWGLSHRFAGSGDRAALSGLIFDALRRRASC
CCCCHHHHHHHHHHHHHHHHCCCCCCHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
AHVMGSEEPRALLLGMLATVRGLDVDAIAKLCDGARFAPAPLSEDERTRLASPSLEGAAP
HHHCCCCCHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCCCCCCHHHHHCCCCCCCCCC
WVRGDYPQWLDGELKAMFGEERVAEAEALAARAPVDMRVNTLKAKPEEALAELAHLHPEP
CCCCCCCCCCCCHHHHHHCHHHHHHHHHHHHCCCCCEEEHHCCCCHHHHHHHHHHCCCCC
GQWSPLALRIPLGADGKQPPITSEPAFVKGGVEVQDEGSQIAAILAAPMPGSQVLDLCAG
CCCCCEEEEEECCCCCCCCCCCCCCCEEECCEEEECCCCEEEEEEECCCCCHHHHHHHHC
AGGKTLELAALMDNKGQLYAHDSDVRRLKPIHERLQRAGVRNVQIRAPRGTADVLSDLEG
CCCCEEEEEEEECCCCCEEEECCHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHCC
HMDLVLVDAPCTGTGTWRRNPDAKWRVRPGALAERTAEQAKILEQAVRYVKPGGRLAYVT
CEEEEEEECCCCCCCCCCCCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEE
CSLLNSENAGQIRALLEKHPDFSVVPSTEAVLALGSRGLALRQAALDLPEGLMLTPRRTG
EEECCCCCHHHHHHHHHCCCCCEECCCCHHHHHHCCCCHHHHHHHHCCCCCCEECCCCCC
TDGFFISVLKRAA
CCHHHHHHHHHCC
>Mature Secondary Structure 
TPSARLSAAIDILADIIARRRPAGDAIKDWGLSHRFAGSGDRAALSGLIFDALRRRASC
CCCHHHHHHHHHHHHHHHHCCCCCCHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
AHVMGSEEPRALLLGMLATVRGLDVDAIAKLCDGARFAPAPLSEDERTRLASPSLEGAAP
HHHCCCCCHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCCCCCCHHHHHCCCCCCCCCC
WVRGDYPQWLDGELKAMFGEERVAEAEALAARAPVDMRVNTLKAKPEEALAELAHLHPEP
CCCCCCCCCCCCHHHHHHCHHHHHHHHHHHHCCCCCEEEHHCCCCHHHHHHHHHHCCCCC
GQWSPLALRIPLGADGKQPPITSEPAFVKGGVEVQDEGSQIAAILAAPMPGSQVLDLCAG
CCCCCEEEEEECCCCCCCCCCCCCCCEEECCEEEECCCCEEEEEEECCCCCHHHHHHHHC
AGGKTLELAALMDNKGQLYAHDSDVRRLKPIHERLQRAGVRNVQIRAPRGTADVLSDLEG
CCCCEEEEEEEECCCCCEEEECCHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHCC
HMDLVLVDAPCTGTGTWRRNPDAKWRVRPGALAERTAEQAKILEQAVRYVKPGGRLAYVT
CEEEEEEECCCCCCCCCCCCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEE
CSLLNSENAGQIRALLEKHPDFSVVPSTEAVLALGSRGLALRQAALDLPEGLMLTPRRTG
EEECCCCCHHHHHHHHHCCCCCEECCCCHHHHHHCCCCHHHHHHHHCCCCCCEECCCCCC
TDGFFISVLKRAA
CCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]